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Progress in dissymmetric Gemini surfactants;2. A series of dissymmetric Gemini surfactants with the structure ofC_(12H_(25)CH_(3_(2)N~CH_(2_(4)N~CH_(3_(2)C_mH_(2m+1),denoted as C_(12)-4-C_m(m is 14,16,18),have been synthesized with N,N-dimethylalkylamine and 1,4-dibromobutane as the initial reagents.

以N,N-二甲基脂肪胺和1,4-二溴丁烷为原料,合成了一系列具有不同疏水链的不对称Gemini表面活性剂C12H25(CH3)2N+(CH2)4N+(CH3)2CmH2m+1(C12-4-Cm,m=12,14,16,18),并通过1H NMR、MS和元素分析等方法鉴定其结构。

We investigated the effects of specificPDE-3 inhibitors (olprinone, milrinone, and amrinone) on contractedhuman gastroepiploic arteries ( n = 70), internal mammary arteries( n = 72), and radial arteries ( n = 70) harvested from a totalof 134 patients, all of whom were undergoing coronary arterybypass surgery.

我们在总共134例行冠脉搭桥手术患者身上采集了人胃网膜动脉( n = 70)、乳内动脉( n = 72)和挠动脉( n = 70),并探讨了特异性 PDE -3抑制剂(奥普力农、米力农和氨力农)对这些血管收缩的影响。

This invention pertains to compounds of Formula I, their N-oxides and suitable salts wherein A is O or S; G is a 5- or 6-membered heteroaromatic ring or a 5- or 6-membered nonaromatic heterocyclic ring optionally including one or two ring members selected from the group consisting of C, SO or S2, each ring optionally substituted with from one to four R; each J is independently a phenyl ring, a 5- or 6-membered heteroaromatic ring or an aromatic 8-, 9- or 10-membered fused carbobicyclic or heterobicyclic ring system, wherein each ring or ring system is optionally substituted with from one to four R; and R, R, R, R and n are as defined in the disclosure.

本发明涉及式I的化合物、其N-氧化物和适当盐,其中A是O或S;G是任选地包含一个或两个独立选自C、SO或S 2 的环成员的5-或6-员杂芳环或5-或6-员非芳族杂环,各环任选地被1-4个R 2 取代;各J独立地是苯环,5-或6-员杂芳环或芳族8-,9-或10-员稠合的碳二环或杂二环系,其中各环或环系任选地被1-4个R 3 取代;R 1 ,R 2 ,R 3 ,R 4 和n如说明书中定义。

One hundred and thirty male Wistar rats were randomly divided into sham scald group (n=10), thermal injury group (n=60, 40 ml/kg normal saline was infused peritoneally 6 hours postburn), and Xuebijing treatment group (n=60, 4 ml/kg Xuebijing injection was injected twice a day in addition to delayed resuscitation).

采用大鼠30%总体表面积Ⅲ度烫伤模型。130只雄性Wistar大鼠按随机数字表法分为假伤组(n=10)、烫伤组(n=60,伤后6 h腹腔内注射40 ml/kg生理盐水)和血必净组(n=60,血必净注射液4 ml/kg,每日2次)。

To explore new synthetic methods, we set out a careful investigation of the reaction of benzimidazolium salt with many nucleophilic agents, including the active aromatic compounds and heteratom nucleophilic agents, and found that the quaternary C=N is not so active; when benzimidazolium salt is reacted with big nitrogen nucleophilic agent? phthalimide, it does not give the expected addition product, instead, produces N-alkyl phthalimide through alkyl-transfermation from benzimidazolium salt to phthalimide.

为了开发新的合成方法,研究了苯并咪唑盐与各种亲核试剂(活泼芳环与杂原子亲核试剂)的反应,发现苯并咪唑盐不与活泼芳环及杂原子亲核试剂发生2位加成反应;在与体积较大的位阻型N亲核试剂邻苯二甲酚亚胺反应时,未得到亲核试剂与极化的C=N的加成产物,而是得到N烷基化的邻苯二甲酰亚胺,进一步研究表明,苯并咪唑盐将1(3)位N上的烷基转移给了邻苯二甲酰亚胺,并讨论了其反应机理和取代基,溶剂效应。

With diluted anaerobically pretreated wastewater from a pig farm and Spirodela oligorrhiza, TN, NH(superscript + subscript 4)-N and NO(superscript – subscript x)-N removal pathways in shallow-water duckweed-based wastewater treatment systems were studied in summer and winter.

以稀释的猪场厌氧污水为供试水样,少根紫萍为供试生物材料,对夏、冬2季浅水体浮萍污水净化系统TN、NH(上标+下标 4)-N和NO-N(NO(上标–下标 2)-N与NO(上标–下标 3)-N之和)的去除途径进行了试验研究。

With diluted anaerobically pretreated wastewater from a pig farm and Spirodela oligorrhiza,TN,NH~+_4-N and NO~-_x-N removal pathways in shallow-water duckweed-based wastewater treatment systems were studied in summer and winter.

以稀释的猪场厌氧污水为供试水样,少根紫萍为供试生物材料,对夏、冬2季浅水体浮萍污水净化系统TN、NH4+-N和NOx--N(NO2--N与NO3--N之和)的去除途径进行了试验研究。

In this paper,by the matrix method,a necessary and sufficient condition for two n-dimensional synclastic simplexes to be able embedded in the n-dimensional Euclidean space is obtained,as well as for two group finite point sets.

该文利用矩阵的方法,获得了两个同向的n维单形同时等距嵌入E~n维欧氏空间的一个充分必要条件是:对于预给(n+1)~2个距离,满足一组具有行列式形式的不等式组det,由此可以得到两组等数量的有限点集合到E~n维欧氏空间中等长嵌入的一个充分必要条件。

N - Fmoc - L - B - homoglutamine and N - Fmoc - L - B - homoasparagine have been prepared by anidt - eistert synthesis from commercially available N - Fmoc - L - a - glutamine and Na - Fmoc - Nr - trityl - L -asparagine.

描述了应用Arndt-Eistert反应合成两种含酰胺基的N-Fmoc-L-β-氨基酸的方法,讨论了在Wolff重排过程中,N-Fmoc-L-α-谷氨酰胺重氮甲基酮和N-Fmoc-L-α-天冬酰胺重氮甲基酮的各自特点及反应过程中生成的副产物。

A one-step method for the synthesis of aromatic indolizine derivatives byintramolecular 1,5-dipolar cyclization reaction of 2-(2-arylethenyl)pyridinium N-ylidesin the presence of an oxidant has been studied for the first time. In the presence ofelectron-deficient olefins, however, 2-(2-phenylethenyl)pyridinium N-ylides underwent1,3-dipolar cycloadditions and then aromatized in situ by TPCD to produce indolizinederivatives, indicating 1,3-dipolar cycloaddition proceed more readily than 1 ,5-dipolarcyclization in these conditions. Pyridinium disubstituted N-ylides, readily obtainedfrom corresponding pridinium and β-chlorovinyl ketone, underwent thermalintramolecular 1,5-dipolar cyclization to give indolizine derivatives easily.Indolizinecarbaldehyde derivatives were synthesized starting from 2-pyridinecarbaldehyde in four-steps involving 1,3-dipolar cycloaddition reaction.

本文首次研究了2-(2-芳基乙烯基)吡啶N-叶立德在氧化剂存在下的分子内1,5-偶极环化反应,采用一锅法合成了中氮茚衍生物;研究了这些N-叶立德的1,5-偶极环化和1,3-偶极环加成反应的选择性,发现当有缺电子烯烃存在时,优先进行1,3-偶极环加成反应,而不再发生分子内1,5-偶极环化反应;由β-氯乙烯酮方便地得到了烯丙基N-叶立德,他们在加热时进行分子内1,5-偶极环化反应而得到中氮茚衍生物;由2-吡啶甲醛为起始原料,通过1,3-偶极环加成反应等四步反应,得到了重要的中氮茚甲醛衍生物,这些反应都具有条件温和和操作简便的特点,是合成中氮茚衍生物的新方法。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.

聚光:照片上是建在西班牙桑路卡拉马尤城的一座新型PS20塔式太阳能电站。被称为&日光反射装置&的镜子将太阳光反射到主塔,然后用聚集的热量产生蒸汽进而通过涡轮机转化为电力