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A multinational team coordinated by Tom Misteli at the National Cancer Institute of the National Institutes of Health in Bethesda, Md., has found that, in mice with a disease resembling Emery-Dreifuss muscular dystrophy, lamin A or C protein defects interfere with the way cell nuclei normally localize in skeletal-muscle fibers at the point where each fiber receives signals from a nerve cell.

由美国国立卫生研究院所属的国家癌症研究院的研究者Tom Misteli所领导的多国合作的研究团队在对 Emery-Dreifuss muscular dystrophy Emery-Dreifuss进行性肌营养不良实验鼠的研究中,发现了这些实验鼠的不正常的lamin A 或 C 蛋白,干扰了骨骼肌细胞核在骨骼肌细胞中的正确位置,而这一位置正是肌肉细胞从神经细胞处接受刺激信号的地方。

The results show that the deformation feature during creep produced in the primary stage is that a great deal of $\langle a\rangle$ dislocation is activated on basal and non--basal planes, and $\langle a+c\rangle$ dislocation slips on pyramidal planes.

结果表明,蠕变初期的变形特征是:大量形变产生的 a 位错在合金的基面和非基面滑移, a +c位错在锥面滑移。

On curing, the -NCH〓OH groups of PNMA film would condense with each other to form a network of PNMA in which the PA molecular long chains were be"tightened"in bundles, or be confined in the meshes of the networks. 2. During the developing process of the low-temperature curable, non-formaldehyde PA latices, the monomers were chosen based on the organic/inorganic ratios, and the co-polymerization reactivity ratios. The effects of crosslinking monomer A and B were also compared.

从物质的有机性/无机性值,以及多元单体发生共聚的条件出发,通过比较交联单体A与B的性能,发现采用交联单体A的胶乳的性能良好,确定了一个由软、硬及交联单体A等多种单体组成的混合体系在阴/非离子组成的复合乳化体系中进行乳液聚合制备所要求的低温无甲醛PA胶乳的配方。

Leucamide A, a bioactive cyclic heptapeptide containing a unique mixed 4,2-bisheterocycle tandem pair consisting of a methyloxazole and thiazole subunit was first isolated from Australian marine sponge Leucetta microraphis.

Leucamide A是从澳大利亚海绵Leucetta microraphis中分离而得到的一种天然环肽化合物,由氨基酸及氨基酸衍生物组成:L—亮氨酸,噁唑,L-丙氨酸,甲基噁唑,噻唑,L—缬氨酸和L-脯氨酸。

Black Summer Days is a Taiwanese rock band loved by many in the indie scene. This time they have worked with Lithoglyph Inc. and produced what they called a "band app" so that you can learn their latest activities on your iPhone or iPod Touch. Also featured are four latest clips of their performance:"Tell Her Your Lie","Problem Child","Sure Distance" and "Y.A."

Black Summer Days 2005 年在台北成军,是四位全心全意将自己奉献给音乐的摇滚男儿所组成的乐团,BSD 这次透过 iPhone 平台,推出全新行动 EP -「Y.A」,包含四首全新录制的单曲-〈对他说谎〉、〈Problem Child〉、〈安全距离〉与〈Y.A〉,让您透过您的 iPhone,经历一场属於自由精神的摇滚洗礼!

Figure 3. A, Transabdominal scan of the right adnexa shows a complex mass surrounded by pelvic structures containing several round areas of loculated fluid that vary in size and are separated by a thickened band or adhesion, simulating a tubo-ovarian abscess or complex. B, Transabdominal cross-sectional scan shows the 2 loculated fluid areas posterior to the uterus separated by a thickened adhesion band.

图3 A,右侧附件区经腹部扫描显示被盆腔结构环绕的混合性肿块,其内有数个圆形的局限性积液,其大小不等,被增厚的束带或粘连分隔,象是一个输卵管-卵巢脓肿或复合体。B,经腹部横切面扫描显示子宫后方的2个局限性积液区,被一增厚的粘连束带所分隔。

Figure 3. A, Transabdominal scan of the right adnexa shows a complex mass surrounded by pelic structures containing seeral round areas of loculated fluid that ary in size and are separated by a thickened band or adhesion, simulating a tubo-oarian abscess or complex. B, Transabdominal cross-sectional scan shows the 2 loculated fluid areas posterior to the uterus separated by a thickened adhesion band.

图3 A,右侧附件区经腹部扫描显示被盆腔结构环绕的混合性肿块,其内有数个圆形的局限性积液,其大小不等,被增厚的束带或粘连分隔,象是一个输卵管-卵巢脓肿或复合体。B,经腹部横切面扫描显示子宫后方的2个局限性积液区,被一增厚的粘连束带所分隔。

The patients in the group A were given with mifepristone 10 mg once daily and nemestran 5 mg twice a week by mouth for 3 months,while the patients in the group B with mifepristone and placebo in the same dose and way as group A.The dimension of uterus and myoma was monitored respectively by B-mode ultrasound before and after treatment,the levels of estrogen,progesterone and hemoglobin as well as liver and renal functions were all measured at the same time.The side effects of drugs were assessed.Results:The results showed that the menoschesis occurred,and the distend and pain of hypogastric region and anemia were redressed in all patients during the treatment.

将绝经前有症状的子宫肌瘤患者100例随机分成两组,A组50例为小剂量米非司酮联合内美通组,每天口服米非司酮10 mg,同时口服内美通5 mg,每周2次,连服3个月。B组50例为米非司酮组,每天口服米非司酮及安慰剂,剂量与服药方法同A组;治疗前后B超测量子宫体积、肌瘤体积;检测用药前后雌、孕激素、血红蛋白和肝肾功能,观察服药后的不良反应。

They all contain 13 protein coding gene,2 rRNA gene,22 tRNA gene and 1 D-Loop.The base composition for the four nucleotides is A-32.0%,C-27.6%,G-14.7%,T-25.8%,And it is A-32.5%,C-26.9%,G-14.1%,T-26.5%for Yellow-throated Marten.But there are some definite differences in base composition,the using of Initiation codon and Stop codon,and the mode of repeat sequences in control region.The codon usages of Manes have bias,and the ttiird locations of codon of protein-coding genes have the higher frequency in using A and C.There may be some relativity with the content of A and C in D-loop,namely,it has relation with the mode of repeat sequences.The complete mitochondrial genome of the Sable and Yellow-throated Marten were submitted to GenBank,and the accession number are FJ429093 and FJ719367 respectively.3、The complete mitochondrial genome of 6 other species of Mustelidae from GenBank and some sequences of D-loop from the 6 species were aligned.

分析紫貂大兴安岭亚种、长白山亚种、阿尔泰亚种和北欧亚种间的基因流及进化历史得知:大兴安岭种群与新疆种群和长白山种群间的基因流水平最高(Nm=0.1260和0.1427),新疆与长白山种群间最低Nm=0.0053紫貂种群在进化过程中可能发生过种群膨胀,经历过种群增长过程。2、对紫貂和黄喉貂的线粒体全基因组结构进行分析发现:全长分别为16 523bp和16549bp,均包含13个蛋白质编码基因、2个rRNA基因、22个tRNA基因和1个非编码序列区(D-Loop区,紫貂全序列中碱基组成为A-32.0%,C-27.6%,G-14.7%,T-25.8%,黄喉貂为A-32.5%,C-26.9%,G-14.1%,T-26.5%;基因排列顺序与日本貂和貂熊的一致,但碱基组成、起始密码子和终止密码子的使用及控制区中串联重复序列模式等均存在一定差异。

Moreover, the actual allele frequency of most varieties deviates far from Hardy-Weinberg equilibrium. All PPB、na 、I、h、Gi and Fst have proved to be the references to elucidate that ISSR is a most powerful tool to analyze genetic diversity, compared with the RAPD marker and the allozyme marker is less strong ordinally. We could divided the 70 samples into A, B, C, D and E five groups using three methods according to genetic distance clustering. There is a bit displacement for few varieties in different clustering maps, but the most are similar to morphological analysis despite that there is still a great difference among cultivars in the same one group. The above results imply that the three methods have the different sensitivity and resolution in genetic distance analysis of close varieties. The Mantel test indicates that the results from the three kinds of markers have the significant correlation, which demonstrates that the number of the used three kinds of markers is enough to exactly detect the diversity of all 70 samples to ideal extent. And these methods can be used to evaluate the diversity of the whole group using the miscellaneous samples instead of the individual sample, of the Gerbera jamesonii are mainly from tissue culture plants. In conclusion, the above study results provide a reference for the application of three kinds of molecular markers to molecular marker-assisted breeding of flower. 2. The genetic diversity among the eight introduced cut-flower varieties of Ranunculus asiatica was analyzed by the ISSR markers. Based on the genetic clustering tree, all the colorful flower varieties are clustered into one group, and the white flower varieties into another group. Moreover, among the former group the yellow flower varieties are clustered into one sub-group, and the reddish flower varieties, such as rose color, pink, nacarat, are clusetered into another sub-group.

由三种分子标记的分析结果可以看出,等位基因平均值、观察杂合度、Fis值、Fit值皆较高,表明非洲菊等位基因较丰富,杂合基因偏多,且绝大部份品种的实际等位基因频率在品种内偏离了Hardy-Weinberg equilibrium;PP8、na、Ⅰ、h、Gi及Fst皆表明,ISSR检测遗传多样性的能力最强,其次是RAPD,等位酶最低;根据遗传距离进行聚类,三种方法都把70个品种分成A、B、C、D、E五个大组,每一组中除少数品种发生位移外,大部份品种分类结果相似,且与形态分析结果有相似性,但在每一组中,品种间的聚类差别较大,表明这三种方法在近距离品种间检测遗传变异时灵敏度及分辨力不同;Mantel检测表明,三种标记的分析结果有显著相关性,表明所用的三种分子方法的标记数量已经可以相对无偏地检测到70个品种间遗传变异;非洲菊为组培苗,三种标记的检测结果皆表明,混合样品可以作为个体样品的代表,对整个居群的遗传多样性进行评价;这些研究结果可为三种分子标记方法在花卉分子辅助育种中的进一步应用提供借鉴。

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However, as the name(read-only memory)implies, CD disks cannot be written onorchanged in any way.

然而,正如其名字所指出的那样,CD盘不能写,也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口,替代木托盘,免薰蒸,符合欧盟、北美各国对出口货物包装材料的法令要求;喷涂钢托盘适用于重载上货架之用,托盘表面根据需要制作成平板状、波纹状及间隔形式,满足不同的使用要求。

A single payment file can be uploaded from an ERP system to effect all pan-China RMB payments and overseas payments in all currencies.

付款指令文件可从您的 ERP 系统上传到我们的电子银行系统来只是国内及对海外各种币种付款。