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In a second experiment (n = 7), 100 nM DEX was administered posthypoxia. In a third experiment (n = 7 each group), an 2 antagonist, yohimbine was given with and without 100 nM DEX prehypoxia administration.

第一个试验，在缺氧状态前给予0、10、100nM 的右旋美托咪定（每组 n=7），第二个试验（ n=7），缺氧后给予100nM 右旋美托咪定，第三个试验（ n=7）， 100nM 右旋美托咪定联合或不联合育亨宾（一种α2受体拮抗剂）在缺氧后给予。

The acute toxicities of 2-chloro-4-nitroaniline, 4-chloro-3-nitroaniline, 2-chloro-5-nitroaniline, 2, 4-dichloroaniline, 3, 4-dichloroaniline, 2, 5-dichloroaniline, 2, 3-dichloroaniline to zebra fish were conducted in lab. 48h LC〓 values were 11. 18, 4. 62, 9. 23, 9. 55, 7. 07, 6. 68, 0.62mg/L respectively, and 96h LC〓 values were 6. 99, 2. 58, 8. 63, 7. 79, 6. 08, 5. 23, 0.49mg/L respectively.

1研究了2-氯-4-硝基苯胺、4-氯-3-硝基苯胺、2-氯-5-硝基苯胺、2，4-二氯苯胺、3，4-二氯苯胺、2，5-二氯苯胺、2，3-二氯苯胺对斑马鱼的急性毒性，经计算48h LC〓分别为11.18、4.62、9.23、9.55、7.07、6.68、0.62mg/L，96h LC〓分别为6.99、2.58、8.63、7.79、6.08、5.23、0.49mg/L，这7种化合物均属于高毒物质。

Of the 8 cases, 2 cases showed blood Tb-Ab positive, 1 case was positive to antiacid bacillus of sputum, the rest cases with negative TBAb. 3 patients with 2 showed organs infection, 6 patients passed the tissue biopsy diagnose, body temperature of 6 cases fall to normal after 3-7 days of antituberculotic treatment, mild liver dysfunction appeared in 2 patients, hyperuricemia occurred in 7 patients, in addition, 1 patient developed reject reaction. Among all the cases, 7 cases healed, 1 died of pulmonary fungal infection.

其中2例血Tb-Ab，1例腹水结核抗体阳性，1例痰抗酸杆菌阳性，其余结核抗体阴性，3例患者表现为2个脏器感染，6例通过病理组织活检诊断，6例发热者在抗结核治疗3~7d体温降至正常，2例患者在治疗过程中出现轻度肝功能异常，7例出现高尿酸血症，1例出现移植肾排斥反应。8例患者7例痊愈，1例肺结核患者死于肺部真菌感染。6例发热者在抗结核治疗3~7d体温降至正常。

The synthesis of 4,5,7-trichloroquinoline makes use of ethyl orthoformate, cyanoacetic ester and 3,5-dichloroaniline as the raw materials. The synthesis is completed by four steps: condensation, cyclization, hydrolyzation and chlorination. Several conditions concerned in the process are studied, the whole yield of 4,5,7-trichloroquinoline is about 53%, and the purity of it is about 96%. All the products are testified by IR, NMR and HPLC.

介绍了以3，5-二氯苯胺、原甲酸三乙酯和氰乙酸乙酯为原料，经过缩合、成环、水解和氯代4步反应制备4，5，7-三氯喹啉的方法，对相关的试验条件进行了考察，通过红外光谱、核磁共振谱和液相色谱对4，5，7-三氯喹啉的结构和纯度进行表征和测定，试验结果为4，5，7-三氯喹啉的纯度大于96%，总收率达到53%。

Results The indications for surgery were urinary retention with a large prostate in 78 patients (66.7%),cystolithiasis in 25(21.4%),prostatic bleeding in 9(7.7%), hernia in 7(6.0%) and bladder diverticulum in 5(4.3%).

结果 开放手术的指征中，大体积前列腺引起尿潴留和严重排尿困难者78例，合并膀胱结石25例，前列腺出血9例，腹股沟疝7例，膀胱憩室5例。

The endocellular Fura-2 increased to 2.39,3.14,and 3.24 fold respectively by addition of AA,bullatacin and atemoyacin-A and the accumulation of Dox in MCF-7/ADR cells was similar to that of Fura-2,increased to 2.98,4.10 and 4.24 fold respectively by AA,bullatacin,and atemoyacin-A while no in MCF-7 cells.

细胞内阿霉素的积累与Fura-2 相似，加入AA，bullatacin和atemoyacin-A均分别增加 MCF-7/ADR 细胞内 ADR 的积累至2.98，4.10和4.24倍，而未见显著增加敏感株内 ADR 的积累。bullatacin和atemoyacin-A均能诱导MCF-7与MCF-7/ADR细胞的凋亡，且相同浓度下，两细胞株的凋亡百分数无显著差异。

Combined with available data, it is comidered that the sourcerock of biotite--leptynite might be intermediate-acid volcanic material of ca.2.7 Ga, and that of migmatized leptite and quartzite might come from granitic crust older than 3.0 Ga. The iron formation was formed on the continental crust base at about 2.7 Ga, and was immediately metamorphosed for the first time.

结合已有的研究资料可以认为，黑云变粒岩的原岩来自2.7 Ga左右的中酸性火山物质，浅粒岩和石英岩的原岩来自3.0 Ga以上的花岗质地壳物质；含铁建造形成于陆壳基底之上，形成时间约2.7 Ga，并于2.5—2.7 Ga之间发生首次变质作用。

Objective: To observe the expression of bone morphogenic protein-7 (BMP-7) in the kidney of rats with unilateral ureteral obstruction, and to explore the relationship between BMP-7 and renal tubulointerstitial lesion.

目的：观察单侧输尿管梗阻大鼠模型中骨形态发生蛋白7（BMP-7）在肾组织中的表达部位，动态变化及其与肾小管间质损害的关系。

Results indicate that the number of bacteria grown in media LB, CSEA and WSA was 14.84×10^7, 10.27×10^7 and 6.91×10^7 CFU per gram dry soil, respectively, after 192 h of incubation. The diversity index of soil bacteria was the highest in WSA, while the lowest in LB. Certain similarity was discovered in bacteria community between the three media, i. e. the Jaccard index was 57.69% between LB and CSEA, 53.13% between LB and WSA and 66.67% between CSEA and WSA. Phylogenetic analysis suggests that the dominant bacterial groups in the soil belong to β-Proteobacteria,γ-Proteobacteria and Actinobacteria. The sequence of 16S rDNA of some OTUs was found to have high homology with Burkholderiaceae bacterium, Rhodococcus and Mycobacterium, so it is presumed that the cells of these bacteria can secrete Resuscitation-Promoting Factors, which may effectively improve culturability of soil microorganisms.

结果表明，LB、CSEA、WSA培养基192h后每g干土获得的细菌数量分别为14.84×10^7、10.27×10^7和6.91×10^7CFU，但微生物多样性指数以WSA为最高，LB多样性指数最低；三种培养基培养的细菌菌群有一定的相似性，LB和CSEA培养基间的Jaccard指数为57.69%，LB和WSA培养基之间为53.13%，而CSEA和WSA培养基的相似性指数达66.67%；16SrDNA测序结果表明，所获得的土壤细菌优势种群在分类方面主要属于γ-和β-变形杆菌以及放线菌亚门，其中某些OTUs中的16SrDNA序列与Burkholderiaceae bacterium、Rhodococcus和Mycobacterium属具有较高的同源性，推测其细胞能够分泌复苏促进因子，有效地提高土壤细菌的可培养性。

Methods Six weeks old male Fischer 344 rats (F344) were used as donors, and six weeks old male F344alb as recipients. All F344alb were divided into 4 groups: group Ⅰ(n=10) was untreated; group Ⅱ(n=10) was treated with CCl4 but no γ-irradiation and transplantation; group Ⅲ(n=10) was transplanted with 1×10^7 BMCs after γ-irradiation, but without CCl4 treatment; group Ⅳ(n=10) was transplanted with 1×10^7 BMCs after γ-irradiation, with CCl4 treatment. The BMCs prepared from the donors were infused via the penial veins of recipients immediately after whole body γ-irradiation (7.5Gy) and CCl4 treatment: 4 weeks after BMCs transplantation, CCl4 were injected into peritoneal cavity twice a week for 4 weeks.

雄性F344大鼠为供体，而雄性F344alb为受体，分为4组：组Ⅰ(n=10)为正常对照组，不接受肝损处理，无全身射线照射和阴茎静脉骨髓细胞移植；组Ⅱ(n=10)为肝损无移植组，只接受肝损处理，无全身射线照射和阴茎静脉骨髓细胞移植；组Ⅲ(n=10)为正常移植组，全身射线照射后阴茎静脉移植骨髓细胞1×10^7；组Ⅳ(n=10)为肝损移植组，接受CCl4注射肝损，全身射线照射后阴茎静脉骨髓细胞移植1×10^7BMCs，其中，γ-照射剂量为7.5Gy，F344大鼠的BMCs经受体的阴茎静脉注入。

It seems likely that Kraft will return with a better offer.

看起来卡夫要重新考虑一个更好的出价了。

But he'd rather burn off my feelers and watch me squirm.

可他却放任那个家伙对我为所欲为！