查询词典 3-D

Methods Starting from 2-chloro-4-nitrophenol and 2- pyridine hydrochlorid, 3-chloro-4-(pyridin-2-ylmethoxy) aniline was obtained via etherization and reduction. The obtained aniline coupled with N-(4-chloro-3-cyano-7-ethoxyquinolin-6-yl) acetamide to give 4-[3-chloro-4-(2-pyridylmethoxy) phenylamino]-3-cyano-7-ethoxy-6-N-acetylaminoquinoline. And then it was deacetylated, followed by reacting with4- but-2-enoyl chloride to yield the target compound neratinib.

以2-氯－4-硝基苯酚和2-氯甲基吡啶为起始原料，经醚化、硝基还原得到3-氯－4-（吡啶－2-甲氧基）苯胺，3-氯－4-（吡啶－2-甲氧基）苯胺与3-氰基－6-乙酰氨基－7-乙氧基－4-氯喹啉反应得到3-氰基－6-乙酰氨基－4-［3-氯－4-（吡啶－2-甲氧基）苯氨基］－7-乙氧基喹啉，3-氰基－6-乙酰氨基－4-［3-氯－4-（吡啶－2-甲氧基）苯氨基］－7-乙氧基喹啉去乙酰保护基后，与-4-二甲氨基－2-丁烯酰氯经酰化反应得到ner-atinib。

At Er~(3+) doping concentration range 0.1-1.5 mol%, Er~(3+) first arrived at ~4F_(7/2) energy level by excited state absorption, then rapidly relaxed to ~2H_(11/2) and ~4S_(3/2) energy levels, the population of which increased, the remarkable upconversion green emission was obtained when Er~(3+) directly went back to ground state by radiative transition.

Er~(3+)浓度在0.1-1.5 mol％时，Er~(3+)通过激发态吸收跃迁到~4F_(7／2)能级，后迅速无辐射弛豫到~2H_(11／2)、~4S_(3／2)能级，~2H_(11／2)和~4S_(3／2)能级上Er~(3+)的布居数增多，Er~(3+)直接辐射跃迁回基态，上转换发射以绿光为主。

Contrast-enhanced Ultrasound(1) Renal occupied lesions: the contrast-enhanced imaging feature of renal cell carcinomas are multiformity. It was different in time of start-enhancing and start- expurgation and intensio.3 cases revealed wash-in contemporarily and 6 cases revealed wash- in quickly in time of start-enh ancing.In time of start-expurgating, 3 cases showed wash-out quickly, 3cases revealed wash-out contemporarily,3 cases showed wash-out slowly,6 cases revealed a higher contrast enhancement and 3 cases revealed a even contrast enhancement in enhancing intension; 4 cases with renal cyst s,outline had more clear and inside had no contrast media washing in and enhancing;3cases with renal angiomyolipomas washed in slowly,washed out slowly and equal or low enhanced ; 2cases with renal columnar hypertrophy were no outline appearance and the same enhancement and ech o as the nomal rena tissue.

超声造影诊断结果：(1)肾占位性病变：9例肾透明细胞癌，其超声造影表现多种多样，造影后肾脏恶性病灶造影开始增强的时间、开始廓清的时间及增强强度不等，在开始增强的时间方面，与正常肾皮质同时灌注增强的有3例，表现为快进的有6例，在开始廓清的时间方面，快退3例，同退3例，慢退3例，在增强的强度方面，6例病灶表现为高增强，3例为等增强表现；4例肾囊性病灶，超声造影轮廓较二维超声清晰，但内部始终未见增强；3例肾血管平滑肌脂肪瘤表现为慢进慢退，回声呈等、低增强表现；2例肾柱肥大超声造影无明显包块轮廓出现，造影增强的动态变化时间、强度与正常肾组织一致。

GC/MS analysis on the leaf oil indicated that the main components with a relative content of ≥3% were alloocimene (43.22%),α-pinene (13.63%),γ-terpinene (5.49%),-3, 7-dimethyl-, 2, 6-octadien-1-ol (3.58%),β-fenchyl alcohol (4.58%), and 2-amino-3, 5-dicyano-6-(4-methoxyphenoxy)-pyridine (3.67%).

用GC/MS联用方法，对巨尾桉挥发油进行鉴定，相对百分含量在3%以上的化合物有：α-蒎烯(13.63%)、别罗勒烯(43.22%)、γ-萜品烯(5.49%)、3，7-二甲基－2，6-辛二烯醇(3.58%)、β-小茴香醇(4.58%)和2-氨基－3，5-二氰基-6-（4-甲氧基苯氧基）－吡啶(3.67%)。

Further proceed intersection analysis and focus on children studies. The result indicates that experimental diagnosis based on RT-PCR, is homogeneity and the relation between norovirus and the symptoms of acute gastroenteritis is significant (OR, 2.7;95%CI, 2.2-3.2). Equally, the surveillance studies (OR, 2.5;95%CI, 2.1-3.0), outbreak studies(OR,4.7; 95%CI, 3.2-7.1), hospital-based studies(OR, 2.8; 95%CI, 2.0-4.1), and community-based studies(OR, 2.0; 95%CI, 1.2-3.3) have the same result as the former.

进一步将研究对象为孩童的文献进行交叉分层分析，结果发现，以孩童为研究对象的文献中，实验室诊断以基因体RNA为侦测标的的研究，其效果量具有同质性，且诺罗病毒与急性肠胃炎症状的相关性在此分层是显著的（OR=2.7，95%CI： 2.2-3.2），资料来源为监测性研究（OR=2.5，95%CI： 2.1-3.0）或疫情爆发研究（OR=4.7，95%CI： 3.2-7.1）以及研究场所为医院（OR=2.8，95%CI： 2.0-4.1）及社区（OR=2.0，95%CI： 1.2-3.3）的研究亦有相同结果。

Results Tuberculosis lymph gland inflammation coverd highest rate:546 cases (36%) in tuberculosis node was 252 cases (46.2%),lymphonode period was 184 cases (33.7%),early tuberculosis lymphagland inflammation was 233 cases (44.7%).Metastasis cancer followed it:430 cases (28.3%) in which undivided cancer was 156 cases (32.3%),glandular cancer 132 cases (30.7%),epithelial cancer 114 cases (26.3%), chronic lymph glandular inflammation was 352 cases,Non-Hodgkin's lymph-tumor 98 cases (6.5%) in which B lymphocyte type covered 70 cases (71.4%),T lymphocyte covered 17 cases (17.3%),NK cells type covered 11 cases (11.3%) tumor were sacrce.

结果 结核性淋巴腺炎发病率最高，有546例(36.0%)，结核结节期为主，252例(46.2%)，淋巴结节期184例(33.7%)，其中早期结核性淋巴腺炎233例(44.7%)，转移癌次之有430例(28.3%)，其中以未分化癌为主，156例(32.3%)，腺癌132例(30.7%)，鳞癌114例(26.3%)，而慢性淋巴腺炎352例，占第三位，非霍奇金淋巴瘤98例(6.5%)，以B淋巴细胞型为主70例(71.4%)，T淋巴细胞型17例(17.3%)，NK细胞型11例(11.3%)，其中肿瘤较少见。

Results Tuberculosis lymph gland inflammation coverd highest rate:546 cases (36%) in which tuberculosis node was 252 cases (46.2%),lymphonode period was 184 cases (33.7%),early tuberculosis lymphagland inflammation was 233 cases (44.7%).Metastasis cancer followed it:430 cases (28.3%) in which undivided cancer was 156 cases (32.3%),glandular cancer 132 cases (30.7%),epithelial cancer 114 cases (26.3%), chronic lymph glandular inflammation was 352 cases,Non-Hodgkin's lymph-tumor 98 cases (6.5%) in which B lymphocyte type covered 70 cases (71.4%),T lymphocyte covered 17 cases (17.3%),NK cells type covered 11 cases (11.3%) tumor were sacrce.

结果 结核性淋巴腺炎发病率最高，有546例(36.0%)，结核结节期为主，252例(46.2%)，淋巴结节期184例(33.7%)，其中早期结核性淋巴腺炎233例(44.7%)，转移癌次之有430例(28.3%)，其中以未分化癌为主，156例(32.3%)，腺癌132例(30.7%)，鳞癌114例(26.3%)，而慢性淋巴腺炎352例，占第三位，非霍奇金淋巴瘤98例(6.5%)，以B淋巴细胞型为主70例(71.4%)，T淋巴细胞型17例(17.3%)，NK细胞型11例(11.3%)，其中肿瘤较少见。

N-Methyl-3,3-dimethyl spiroindoline-2,3'[3H] naphthaline [2,1-b] [1,4] oxazine was synthesized by 1,3,3-trimethyl-2-methylene indoline and 1-nitroso-2-naphthol, its UV and IR spectra and elemental analysis were carried out, and the photochromism and main influencing factors such as temperature, solvent and pH were studied.

以1，3，3-三甲基－2-亚甲基吲哚啉和1-亚硝基－2-萘酚为原料合成了N-甲基－3，3-二甲基螺吲哚啉-2，3'[3H]萘并[2，1-b][1，4]恶嗪，对其进行了紫外和红外光谱以及元素分析，并对其光致变色性质以及主要影响因素温度、溶剂和pH进行了研究。

RESULTS: Melatonin significantly reduced the anxiety scores from 5, 3.5-6 to 3, 2-3 after premedication and to 3, 2-3.5 during surgery (P = 0.04 and P = 0.005 compared with the placebo group, respectively).

结果：褪黑素显著降低焦虑评分。给药前中位数及四分位数间距为5， 3.5-6。给药后中位数及四分位数间距为3， 2-3，术中为3， 2-3.5(P=0.04并且和分别和对照组相比 P=0.005)。

The invention provides the flux-cored wire for welding the duplex stainless steel, 17 percent to 24 percent flux-cored powder is filled into stainless steel belt. The invention is characterized in that the mass percent of the components of the flux-cored is as follows: 35 percent to 40 percent of chromium powder, 11 percent to 15 percent of molybdenum powder, 2 percent to 4 percent of nickel powder, 3 percent to 5 percent of manganese powder, 1 percent to 5 percent of magnesia chrome, 1 percent to 3 percent of ferrosilicon, 4 percent to 9 percent of rock crystal, 2 percent to 6 percent of feldspar, 21 percent to 30 percent of rutile, 0.5 percent to 4 percent of Al2O3, 0 percent to 5 percent of zircon, 0.5 percent to 3 percent of Bi2O3, and 0.5 percent to 3 percent of manganese nitride.

一种用于焊接双相不锈钢的药芯焊丝，将药芯粉末以17～24％填充在不锈钢带内，其特征在于，所述的药芯质量百分比成分如下：35～40％的金属铬粉，11～15％的金属钼粉，2～4％的金属镍粉，3～5％的金属锰粉，1～5％的铝镁合金，1～3％的硅铁，4～9％的石英，2～6％的长石，21～30％的金红石，0.5～4％的Al 2 O 3 ，0～5％的锆英石，0.5～3％的Bi 2 O 3 ，0.5～3％的氮化锰。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失