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Thirdly, The preparation of 3-aryl-5-substituted-ethenyl isoxazoles and l-isoxazolyl-2-isoxazolinyl substituted-ethenes was developed through 1, 3-dipolar cycloaddition of nitrile oxides,α-alkylation reaction and another 1, 3-dipolar cycloaddition of nitrile oxides based on polystyrene-supported propargyl selenide.

三、从聚苯乙烯负载的炔丙基硒醚出发,经过腈氧化物的1,3-偶极环加成反应、α-烷基化反应和腈氧化物的1,3-偶极环加成反应固相分别合成了3-芳基5-取代--乙烯基异噁唑和1—异噁唑—2—异噁唑啉取代的-乙烯。

Leaves 6–8 per ultimate branch; sheaths 6–9 cm, often white powdery; auricles inconspicuous; oral setae numerous, 2–3 mm; blade oblong-lanceolate or linear-lanceolate, 18–30 × 2–3.5 cm. Pseudospikelets fusiform, 2–3.5 cm, glabrous; prophyll ovate or ovate-lanceolate, 4–8 mm, thin, translucent, apex obtuse, keels 2, ciliate; bracts 1 to several, oblong to oblong-lanceolate, 7–22 mm, papery, many veined, apex obtuse to acute or mucronate; rachilla disarticulating.

每末级的分枝叶6-8;鞘6-9厘米,通常白色粉状;叶耳不明显;口头的刚毛多数,2-3毫米;叶片长圆状披针形披针形或线形, 18-30 * 2-3.5 纺锤形的厘米Pseudospikelets,2-3.5厘米,无毛;先出叶卵形或卵状披针形,4-8毫米,薄,半透明,先端钝,龙骨2,纤毛;苞片1到数个,长圆形到长圆状披针形,7-22毫米,纸质,很多脉,先端钝的到锐尖或短尖;小穗轴脱节。

Upon mild oxidation of Ⅸwith iodine in potassium iodide, a disulfide, which was characterized as 3,3'-dithiobis [2-(l-hydroxyethylidene)-3-imino propionitrile], was formed.

将IX用碘/碘化钾温和地氧化得到二硫化物(XIV,即3,3'-二硫-双2-(1-羟乙叉基)-3-亚胺基丙腈。

Inflorescence development was divided into four stages, the initiating expansion pseudobulb, initiating inflorescence (1-3 cm in flower stalk length), the initial-branching flower stalk, and full bloom inflorescence, respectively. The activity variations of mannan cleaving enzymes,-mannosidase (EC 3.2.1.25), endo--mannanase (EC 3.2.1.78), and the mannan synthesizing enzyme, GDP-mannose pyrophosphorylase (EC 2.7.7.13), were analyzed during different stages to better understand the role of mannan-metabolizing enzymes during inflorescence development of the Oncidium.

将花梗发育过程分为四个阶段,分别为假球茎刚膨大、刚抽梗(花梗长度约1-3公分)、花梗刚分叉以及花盛开,分析参与分解甘露聚醣之酵素-β-mannosidase(EC 3.2.1.25)及endo-β-mannanase(EC 3.2.1.78),与合成甘露聚醣之酵素-GDP-mannose pyrophosphorylase(EC 2.7.7.13),在不同阶段假球茎内的活性变化,了解在花梗发育过程中代谢甘露聚醣之相关酵素所扮演的角色。

Results Among 12 normal conjunctiva, there were 3 weakly positive, 3 positive and 6 negative; while among 15 pterygial specimens, there were 1 negative, 3 weakly positive, 7 positive and 5 strong positive.

结果 12例正常结膜中,6例为阴性,3例VEGF蛋白染色弱阳性,3例为阳性;15例翼状胬肉组织中,1例VEGF蛋白染色阴性,3例为弱阳性,7例为阳性,5例为强阳性。

Two novel pyrazolone derivatives 2-ethylamino-6H-5-(1-phenyl-3-methyl/phenyl-5-pyrazolone-4-ylene)-1,3,4-thiadiazine (PMCP-ETSC/DPCP-ETSC) containing NNS six-membered heterocycles were synthesized by the condensation reaction of 1-phenyl-3-methyl/phenyl-4-chloroacetyl-pyrazolone-5 with 4-ethyithiosemicarbazide. The title compounds were characterized by elemental analysis, IR, 1H NMR, 13C NMR and single-crystal X-ray diffraction.

利用1-苯基-3-甲基/苯基-4-氯乙酰基-吡唑啉酮-5与4-乙基氨基硫脲发生缩合反应,生成了2个新的双杂环化合物2-乙氨基-6H-5-(1-苯基-3-甲基/苯基-5-吡唑啉酮-4-基)-1,3,4-噻二嗪(PMCP-ETSC/DPCP-ETSC),并对其进行元素分析、红外光谱、核磁共振表征和晶体结构分析。

In order to search for the new pyrazolyl-heterocycles lead compounds, eight pyrazolyl- were synthesized from 3-ethyl-1-methyl- 4-substituted-5-pyrazolecarboxylic acid chloride and nitrogen heterocyclic rings such as 3-methyl-5-pyrazolone, 1H-3-ethyl-5-pyrazole ester, etc.

为了寻求新的含吡唑双杂环先导化合物,用 4 取代 1 甲基 3 乙基 5 吡唑甲酰氯与 3 甲基 5 吡唑酮、3 乙基 5 吡唑甲酸乙酯等含氮杂环反应得到了 8个新的含吡唑环的双杂环类化合物。

Culms forming large clumps, erect, 10–50(–120) cm tall, 3–35 mm in diam. Leaf sheaths mostly longer than internodes, smooth; leaf blades linear, flat or inrolled upward, 10–45 × 0.7–1.5 cm, smooth, apex fine, hard, upper blades usually patent; ligule 2–3 mm. Racemes racemosely arranged, 2–6(–12), 7–23 cm, stiff, erect or slightly spreading; spikelets closely overlapping; rachis terminating in a hard bristle up to 5 cm. Spikelets 12–21 mm, pubescent; lower glume 2/3–4/5 as long as spikelet, acute; upper glume lanceolate-oblong, as long as spikelet, acute; lemma lanceolate-oblong, ca. 1 cm, keel scaberulous, pubescent, entirely or in upper half; palea slightly longer than lemma.

形成的秆大丛生,直立,(-120)厘米高,多数叶鞘3-35毫米直径长于,平滑;叶片线形,公寓或向上, 10-45 * 0.7-1.5 厘米,平滑,先端细,硬,上面的叶片通常开展;安排的2-3毫米外消旋体总状分枝的叶舌,2-6(-12),7-23厘米,硬,直立或者稍开展;小穗接近重叠;轴终止在一难的硬毛可达5 厘米小穗12-21毫米,青春期;更低的颖片2/3-4/5倍于小穗,锐尖;上面颖片披针形长圆形,倍于小穗,锐尖;外稃披针形长圆形,约1厘米,微糙,青春期的龙骨,完全或者在上半部;稍微的内稃长于外稃。

Methods The CEA ScFv was radioiodinated (125I,131I) by iodogen solid labelling method.The uptake of radioactivity in tumor and normal tissues in 20 human rectocolonic tumor bearing nude mice was measured at 1,3,6 and 24 hour after peritoneal injection of 125 I-CEA ScFv and in 3 human rectocolonic tumor bearing nude mice imaging was carried out at 1,3,6 and 24 hour after peritoneal injection of 131 I-CEA ScFv.

采用Iodogen法制备125I-CEA ScFv和131I-CEA ScFv.20只荷人结直肠癌裸鼠,腹腔注射125I-CEA ScFv后1、3、6和24 h进行裸鼠的体内分布研究,对3只荷人结直肠癌裸鼠腹腔注射131I-CEA ScFv后1、3、6和24 h进行裸鼠的定位显像研究。

Results After culture and reinfusion in vivo, CD 3 cells, CD 3 CD 8 cells, CD 3, CD 56 cells, cultured cells were significantly elevated, mDC and pDC significantly increased after transfusion, liver function had improved compared with before treatment .

结果 培养结束以及回输体内后, CD 3细胞、CD 3 CD 8细胞、CD 3 CD 8细胞较培养前显著升高,mDC 和pDC 在回输后也明显增高,肝脏功能较治疗前有所好转。

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I didn't watch TV last night, because it .

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