查询词典 3-D

Results Same conservative sites and key catalytic sites existed among SjLDH and LDHs from other species. Similarity of SjLDH compared to CsLDH, TvLDH and HsLDH was 75%, 17%, 58%-60% respectively. Phylogenetic analysis demonstrated that the evolution relation between SjLDH and DmLDH was closer than the relation between SjLDH and CeLDH, the relationship between SjLDH and HsLDH-B,-C was closer than HsLDH-A. Three trans-membrane regions were found, the region of 98aa-106aa in three hydrophilia regions located outside of membrane was inferred as the major antigen epitope. This antigen epitope had significant difference with LDHs from protozoon （ Pf ., Tg ., Tv .） and had 1-3 amino acid residue difference with MmLDH, HsLDH-A,-B,-C, and was the same with CsLDH. One of the key catalytic residues and substrate binding loop were located in this region. Tertiary structure demonstrated that 98aa-106aa was on the surface of the protein and formed a substrate binding loop, other two key catalytic sites were at the position near the loop.

结果 SjLDH与其他物种的同源序列含相同的保守位点及催化活性位点，与华支睾吸虫LDH同源性最高为75％，与阴道毛滴虫LDH同源性最低为17%，与人LDH（HsLDH-A，-B，-C）的同源性为58%~60％； SjLDH与果蝇的进化距离较秀丽隐杆线虫为近，3种人LDH中与HsLDH-B、-C的进化距离较HsLDH-A为近；该蛋白具有3个跨膜区域，3个高亲水性区域，主要的线性表位98aa~106aa位于膜外，与原虫LDH相同区域差异显著，而与其他LDH有1~3个氨基酸的差异，关键催化位点之一及底物丙酮酸结合区域位于该区域，蛋白质同源模建分析表明该区域位于蛋白表面形成环状结构，3个关键催化位点位于该区域或在其附近。

Spikelets oblong, 7–9 mm, florets separated by short rachilla internode not more than 0.6 mm; glumes lanceolate, apex acute; lower glume 4–6 mm, upper glume equal to spikelet, punctiform scabrid; lemmas oblong-lanceolate, 7–9 mm, sparsely pubescent in lower 1/3 or glabrous, scabrid in upper 1/3; awn of lower lemma 1–2 cm, arising from lower 1/3 of lemma back; awn of upper lemma 1–2 mm, arising above middle or near apex.

小穗长圆形，7-9毫米，小花以短分开小穗轴不超过0.6毫米；颖片披针形，先端锐尖；更低的颖片4-6毫米，等于小穗，点状粗糙的上面颖片；长圆状披针形的外稃，7-9毫米，疏生短柔毛在下部1/3的或无毛，在上面1/3粗糙；更低的外稃的芒1-2厘米，生于更低的1/3的外稃背面；上面外稃的芒1-2毫米，出现在中部以上或者近先端。

The mechanism of the interaction between bovine serum albumin and pyrano [4,3-b] pyran derivative, 2-amino-7-methyl-4-(4-nitrophenyl)-5-oxo-4,5-dihydropyrano [4,3-b] pyran-3-carbonitrile, was studied by means of fluorescence spectroscopy under physiological conditions.

用荧光光谱法分析了在生理条件下一种吡喃并[4，3-b]吡喃衍生物-2-氨基-7-甲基-4-(4-硝基苯)-5-氧代-4H，5H-吡喃并[4，3-b]吡喃-3-腈与牛血清白蛋白的作用机制。

On a ZORBAX Stable Bound (2.150 mm, 1.8 m), the rutin、quercitrin、quercitrin-3-O-giucoside and quercitrin-3-O-galactose could be separated completely with 0.05 mol/L potassium dihydrogen phosphate and methanol as mobile phase (40:60,V/V) at a flow rate of 0.3 ml/min and detected with a photodiode array detector .

在色谱柱为ZORBAX Stable Bound (2.150 mm， 1.8 m)，流动相为0.05 mol/L的磷酸二氢钾缓冲溶液-甲醇(40：60，V/V)，流速为0.3 ml/min，在检测波长为360 nm的色谱条件下，芦丁、槲皮素、槲皮素-3-O-葡萄糖苷和槲皮素-3-O-半乳糖苷分离效果好，方法灵敏度高，重现性好，用于测定雪莲果叶中的上述几种黄酮芦丁型黄酮，效果满意。

Synthesis of target compounds namely: to vanillic acid as the starting material with methanol under reflux conditions for 4 - hydroxy -3 - p-methyl, then ether, and nitration, reduction, cyclization reaction 6 - methoxy -7 - benzyloxy-quinazoline -4 - one, and then by the chloride in place of aniline, benzyloxy-off, such as etherification reaction of the target compounds; target compounds with the second and third occurrence of substitution reactions of amines by the TM1, that is, 4 - amino-benzene -6 - methoxy -7 - [2 - hydroxy -3 -(N, N-diethyl amino) oxy c] quinazoline; with ether occurred Ornidazole reaction of TM2, namely, 4 - amino-benzene -6 - methoxy -7 - [2 - hydroxy -3 -(2 - methyl -5 - nitroimidazole) C oxy] quinazoline.

本论文以嘌呤类似物喹唑啉为母核，分别在其4位和7位引入结构多样的取代苯氨基和柔性侧链，设计了一系列4-取代苯胺基-6-甲氧基-7-(2-羟基取代丙氧基)喹唑啉类化合物。目标化合物的合成即：以香草酸为起始原料，与甲醇回流条件下得到4-羟基-3-甲氧基苯甲酸甲酯，然后经过醚化、硝化、还原、环合反应得到6-甲氧基-7-苄氧基喹唑啉-4-酮，然后再经氯化、取代苯胺、脱苄氧基、醚化等反应得到目标化合物；目标化合物与二乙胺发生胺取代反应得到了TM1，即4-苯氨基-6-甲氧基-7-[2-羟基-3-丙氧基]喹唑啉；通过与奥硝唑发生醚化反应得到TM2，即4-苯氨基-6-甲氧基-7-[2-羟基-3-(2-甲基-5-硝基咪唑)丙氧基]喹唑啉。

Patch 3.3.3 introduced a couple of new mounts and I think it's time for a recap!

3.3.3 补丁推出了一系列新的坐骑，我想我们应该重新回顾下！

Result:Among total of 80 cases with non-visualized kidney in IVP,renal parenchyma of 37 cases were non-visualized under ~(99m)Tc-DTPA renography,GFR was 0 ml/min,32 cases carried out nephrectomy;Renal parenchyma of the rest 43 cases were visualized under ~(99m)Tc-DTPA renography,GFR were(20.03±9.64) ml/L,among them 9 cases were carried out nephrectomy, 34 cases received kidney-sparing operation;The 34 cases(divided into 4 groups according to range of GFR) recheck ~(99m)Tc-DTPA renography 2 months later after the operation,Preoperative GFR within(1～10) ml/min,GFR were(4.25±2.99) ml/min,postoperative GFR were(4.00±2.94) ml/min,t=0.522,P＞0.05,indicated no significant change of GFR after the operation; Preoperative GFR within(11～20) ml/min、(21～30) ml/min、(31～40) ml/min groups, preoperative GFR were(15.38±2.63) ml/min、(24.83±2.92) ml/min、(34.25±2.75) ml/min, postoperative GFR were(17.77±3.79) ml/min、(29.42±3.90) ml/min、(40.25±3.50) ml/min respectively,paired t-test,P＜0.05,indicated that 2 months\' postoperative GFR increased significantly,the function of kidneys recovered in some degree.

结果：在80例IVP不显影患肾中，37例患肾在~(99m)Tc-DTPAI肾动态显像上肾实质不显影，GFR为0 ml/min，其中32例行患肾切除；43例患肾在~(99m)Tc-DTPA肾动态显像上肾实质显影，GFR为(20.03±9.64)ml/L，其中9例行患肾切除，34例行保留肾手术；34例保留患肾手术者(根据术前GFR在不同值范围分为4组)在术后2个月返院复查~(9m)Tc-DTPA肾动态显像，GFR值在(1～10)ml/min组(5例)，术前GFR为(4.25±2.99)ml/min，术后2月GFR为(4.00±2.94)ml/min，t=0.522，P＞0.05，表明术后GFR无明显变化；术前GFR在(11～20)ml/min(13例)、(21～30)ml/min(12例)、(31～40)ml/min组(4例)，术前GFR分别为(15.38±2.63)ml/min、(24.83±2.92)ml/min、(34.25±2.75)ml/min，术后2月复查GFR分别为(17.77±3.79)ml/min、(29.42±3.90)ml/min、(40.25±3.50)ml/min，经配对t检验，P＜0.05，有统计学意义，术后2月GFR较术前增高，肾功能有不同程度的恢复。

Types of wine（ from left to right:3 types of Chardonnay,3 types of Riesling,3 types of Cabernet Sauvignon,No.1~9

9款的全家福（从左到右：3款霞多丽，3款雷司令，3款赤霞珠，编号为1~9

So it's a 3 by 3 matrix, 3 equations and unknowns, and what's our right hand side?

因此，它是一个3行3列的矩阵，3个方程三个未知数，我们的右侧是什么呢？

And Homo Sapien fetal brain cDNA Library was used to screen PRL-3-interacting proteins. 3. Identification and bioinformatical analysis of CDH22, a candidate PRL-3-interacting protein Interaction between PRL-3 and CDH22, a candidate PRL-3- interacting protein was identified by GST-pull down assay, co-immunoprecipitation assay and co-localization analysis in vivo and in vitro.

PRL-3相互作用蛋白的鉴定及其功能的生物信息学分析运用基于蛋白质水平的谷胱甘肽-S-转移酶融合蛋白沉淀、免疫共沉淀和共定位分析等技术对酵母双杂交系统初步筛选的结果进行体内和体外的验证。

What would he tell Judith and the children?

他将怎样告诉朱迪丝和孩子们呢？

I this is at that time, the opinion with peacockish true girl is full of in a heart.

这就是当时的我，一个心中布满虚荣的女孩子真实的想法。