查询词典 2-butene

Ten novel derivatives of 1-phenyl-5-[5-(substituted anilinocarbonylmethylthio)-4-phenyl-1,2,4- triazol-3-ylmethylthio]-tetrazole were synthesized rapidly in high yields by the reaction of N--2-chloryacetanilide (3) with 1-phenyl-5-(5-mercapto-4-phenyl-1,2,4-triazol-3-ylmethylthio)-tetrazo- le (2) under microwave irradiation and phase transfer catalysis conditions.

采用微波和相转移催化法通过1-苯基-5-(4-苯基-1，2，4-三唑-5-巯基-3-甲硫基)四唑(2)与2-氯乙酰芳胺(3)反应高效、快速地合成了10种尚未见文献报道的1-苯基-5-[5--4-苯基-1，2，4-三唑-3-甲硫基]四唑。其结构经IR，1HNMR，13CNMR和元素分析表征。生物活性实验结果表明，该类化合物在较低浓度下部分化合物对小麦芽有很好的促进作用

A compound of formula wherein R1 is hydrogen, halo or methoxy; R2 is hydrogen, halo, methyl, ethyl or methoxy; R3 is carboxy, tetrazolyl, or -CONHSO2R where R is methyl, ethyl, phenyl, 2,5-dimethylisoxazolyl or trifluoromethyl; T is -CH2- or -SO2-; and ring A is 3-chlorophenyl, 4-chlorophenyl, 3-trifluoromethylphenyl, 3,4-dichlorophenyl, 3,4-difluorophenyl, 3-fluoro-4-chlorophenyl, 3-chloro-4-fluorophenyl or 2,3-dichloropyrid-5-yl; or a pharmaceutically acceptable salt or prodrug thereof, as well as pharmaceutical compositions containing them are described and claimed.

本发明涉及一种式化合物，其中R 1 是氢原子、卤素或甲氧基；R 2 是氢原子、卤素、甲基、乙基或甲氧基；R 3 是羧基、四唑基或－CONHSO 2 R 4 ，其中R 4 是甲基、乙基、苯基、2，5－二甲基异∴唑基或三氟甲基；T是－CH 2 －或－SO 2 －；环A是3－氯苯基、4－氯苯基、3－三氟甲基苯基、3，4－二氯苯基、3，4－二氟苯基、3－氟－4－氯苯基、3－氯－4－氟苯基或2，3－二氯吡啶－5－基；或其药用允许的盐或前药，还包括所阐述和要求权利的含有它们的药用组合物。

Results Among 581 cases, 569 cases were cured, with the recovery rate of 97.4%; 12 cases died, with the death rate of 2.6%, and the main cause in 2 of the 12 deaths was related to injury of heart and large blood vessels, in 2 to thoracoabdominal injury, in 2 to acute respiratory distress syndrome, and in 6 to thorax injury complicated with severe craniocerebral injury.

结果 全组治愈569例，治愈率97.4%，死亡12例，死亡原因包括伤及心脏及大血管2例，胸腹联合伤2例，ARDS 2例，胸外伤合并重度颅脑损伤6例，死亡率2.6%。

The experimental results indicated that the yield of 2,6-DMN can reach above 38%, when the usage of dimethylnaphthalene was 2g, the temperature reached 18℃, the reaction time was 2.5h, the mole ratio of water-free aluminum trioxide to dimethylnaphthalene was 0.8, the mole ratio of transmethylation agent tetramethylbenzene to dimethylnaphthalene was 1.0, the usage of methane trichloride was 15mL.

结果表明，2-甲基萘(2-MN)使用量为2g时，反应温度为18℃、时间为2.5h、n：n（2-甲基萘）=0.8、n：n（2-甲基萘）=1.0、二氯甲烷用量为15mL时，2，6-DMN的收率可达38%。

Supplemented with 5% coconut milk or 0.2% tryptone in the medium markedly promoted the hypocotyl callus growth, while 0.2% yeast extract had no important effect. Supplemented with 10% coconut milk, 2% tryptone or 2% yeast extract all inhibited the hypocotyl callus growth.

添加5％椰子乳和0.2％胰蛋白胨显著地促进生长，添加0.2％酵母提取液则未表现出显著的促进作用，而10％椰子乳、2％胰蛋白胨和2％酵母提取液均抑制愈伤组织的生长。

Versicolor suited to grow and produce laccases at pH value 3.5-5.7, and unbuffered media were able to get good laccase productivity though buffered media could get higher laccase activity. Metal ions Cu(superscript 2+) and Mn(superscript 2+) in the culture could remarkably increase the activity of laccases. The optimal concentration of Cu(superscript 2+) was 0.008-0.08mmol/L, and the optimal concentration of Mn(superscript 2+) was about 0.01mmol/L, when the culture contained 0.1mmol/L 2,5-dimethoxyaniline.

结果发现该菌种适宜在pH值3.5~5.7环境下生长并合成漆酶，培养基中添加缓冲液可以获得更高的酶活，但不加则有较高的酶产率；铜和锰可以显著提高漆酶活力，当以0.1mmol/L 2，5-二甲基苯胺为诱导剂时，培养基中宜含0.008~0.08mmol/L Cu(上标 2+)，0.01mmol/L左右的Mn(上标 2+)。

The total area of urgent and permanent seismic refuges for evacuation is 441.82 hm^2 and 77.31 hm^2 respectively. The area of urban park and open land available for urgent and permanent seismic refuges for evacuation 300.85 hm^2 and 46.26 hm 2, respectively, and they are spatially unhomogeneous distributed.

12汶川大地震中长期避难人数为30.92万人，所需紧急、固定避震疏散场所总面积分别为441.82hm^2、77.31hm^2，所需紧急、固定避震疏散公园绿地面积分别为300.85hm^2、46.26hm^2。

A general novel synthetic method to Symmetrically or unsymmetrically 2,3,6,7- substituted thieno[2,3-d:5,4-d\']dipyrimidine-4,5(3H,6H)-diones and 2-substituted benzothieno[3,2-d] pyrimidin-4(3H)-dione by utilizing aza-Wittig reaction was proposed firstly. This synthetic method has the advantage of easily accessible starting material, mild condition and good yields.

具体研究内容如下：1、首次研究了应用aza-Wittig反应方法合成2，3，6，7-对称与不对称四取代噻吩并[2，3-d；5，4-d\']双嘧啶-4，5(3H，6H)-二酮以及2-取代苯并噻吩并[3，2-d]嘧啶-4(3H)-酮衍生物的通用新方法，该方法原料易得，条件温和，收率较高。

Finally: In 19 examples only 6 examples examine considered this sickness, misdiagnosing rate is 68.4%, misdiagnoses for the angina pectoris 5 examples, the acute cardiac arrest 2 examples, the acute abdominal pains 2 examples, the uropoiesis is the stone 2 examples, the nervous system disease 2 examples.

结果：19例中仅6例首诊考虑该病，误诊率为68.4%，误诊为心绞痛5例，急性心肌梗死2例，急腹症2例，泌尿系结石2例，神经系统疾病2例。

Philip.2:5 Let this mind be in you, which was also in Christ Jesus: Philip.2:6 Who, being in the form of God, thought it not robbery to be equal with God: Philip.2:7 But made himself of no reputation, and took upon him the form of a servant, and was made in the likeness of men: Philip.2:8 And being found in fashion as a man, he humbled himself, and became obedient unto death, even the death of the cross.

philip.2 ： 5让这个铭记在你意见，而这也是在基督耶稣： philip.2 ： 6人，在形式的上帝，认为这不是抢劫须等同与上帝： philip.2 ： 7 ，而是作出了自己不图虚名，并上台后，他将会成立一个工作人员，以及曾在相似的男子： philip.2 ： 8被发现在时装作为一个男人，他谦卑自己，并成为听话，以至于死，连死亡的十字架上。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐