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We investigated constituent of triterpenoid saponins ofAlbizzia, two new compounds together with two known compounds were isolated from Albizzia julibrissin Durazz. by using column chromatography (macroreticular resin, silica gel, Sephadex gel, reverse phase silica gel),preparative HPLC methods et al.On the basis of spectroscopic analysis, including IR,ESI-MS,~1H-NMR,~(13)C-NMR,HMBC,HMQC,~1H-~1HCOSY and chemical methods, the structure of two new compounds were identified as 3 - O -[β-D-xylopyranosyl(1→2)-β-D-fucopyranosyl (1→6)-β- D -2- deoxy - 2 - acetoamidoglucopyranosyl] -21-O-[(6S)-2- trans- 2,6-dimethyl - 6 - O-β- D - quinovopyranosyl -2,7- octadienoyl] - acacic acid- 28 - O-β-D-glucopyranosyl(1→3)[α-L-arabinofuranosyl(1→4)]-α-L-rhamnopyranosyl(1→2)-β-D-glucopyranoside acacic acid 3- O -β- D- glucopyranosy(1→3)-β- D- fucopyranosl(1→6) [β-D- xylopyranosyl (1→2)]-β-D-glucopyranoside ;two known compounds were acacic acid lactone 3- O -β-D- xylopyranosyl-(1→2)-β-D-fucopyranosl (1→6)- 2-deoxy -2 -acetoamido -β-D- glucopyranoside ; acacic acid lactone 3- O-β-D-xylopyranosyl(1→2)-α-L- arabinopyranosl (1→6)- 2- deoxy - 2- acetoamido -β-D-glucopyranoside . The study lays chemical foundation and chemical reference substance for enhancing quality standard of Albizzia julibrissin Durazz.
本研究论文在综述国内外对合欢属Albizzia三萜皂苷化学成分和药理作用研究进展的基础上,利用传统植化分离手段和现代分离技术,包括大孔树脂、硅胶、葡聚糖凝胶、反相硅胶等柱色谱,制备高效液相色谱法等技术从中药合欢皮中分离得到了4个化合物,其中,2个新化合物和2个己知化合物,并进一步通过现代分析技术IR,ESI-MS,~1H-NMR,~(13C-NMR,HMBC,HMQC,~1H-~1HCOSY等和化学方法鉴定了2个新化合物的结构分别是:3-O-[β-D-吡喃木糖基(1→2)-β-D-吡喃夫糖基(1→6)-β-D-2-去氧-2-乙酰氨基吡喃葡萄糖基]-21-O-[(6S)-2-反式-2,6-二甲基-6-O-β-D-吡喃鸡纳糖基-2,7-辛二烯酸基]-金合欢酸-28-O-α-L-呋喃阿拉伯糖基(1→4)[β-D-吡喃葡萄糖基(1→3)]-α-L-吡喃鼠李糖基(1→2)-β-D-吡喃葡萄糖苷,金合欢酸3-O-β-D-吡喃葡萄糖基(1→3)-β-D-吡喃夫糖基(1→6)[β-D-吡喃木糖基(1→2)]-β-D-吡喃葡萄糖苷;2个已知化合物结构分别是:金和欢酸内酯3-O-β-D-吡喃木糖基(1→2)-β-D-吡喃夫糖基(1→6)-β-D-2-去氧-2-乙酰氨基吡喃葡萄糖苷,金和欢酸内酯3-O-β-D-吡喃木糖基(1→2)-α-L-吡喃阿拉伯糖基(1→6)-β-D-2-去氧-2-乙酰氨基吡喃葡萄糖苷。
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It can be concluded that (1) forosamine on 17-carbon can be easily lost, but difficult for rhamnose sugar;(2) spinosad concentration decreased when irradiation time increased, degrading rate was up to about 70% for irradiating 484 min, and 11 degradates were produced. These degradates were products of the oxidation, reduction, and hydrolytic reactions.
结果表明,多杀菌素17碳上的福乐糖胺容易失去,三氧甲基鼠李糖很稳定;多杀菌素浓度随紫外光照射时间的增加而降低,在照射484 min后,降解率达到70%左右,形成11种降解产物,这些降解产物是多杀菌素A或D经氧化、还原及水解等反应形成。
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Objective To develop a rapid approach of refractive index detection with high performance liquid chromatography for the determination of rhamnose, fructose, glucose, surose and maltose in Lycium barbarum L.
目的 建立同时测定枸杞中鼠李糖、果糖、葡萄糖三种单糖和蔗糖、麦芽糖两种低聚糖含量的高效液相色谱-示差折光检测方法。
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Result:Eight compounds were elucidated as β amyrin palmitate, taraxastery acetate, luteolin 7 O α L rhamanopyranosyl (1→2)β D glucopyranoside,luteolin 7 O β D glucopyranoside, triacontanic acid,β sitosterol, stigmasterol and stigmast 7 en 3β ol.
结果 :从全草中分离得到 5个化合物,β香树脂醇棕榈酸酯,蒲公英醇乙酸酯,木樨草素 7 O α L 鼠李糖基(1→ 2 )β D 葡萄糖苷,木樨草素 7 O β D 葡萄糖苷,三十碳酸;1个混合物,β谷甾醇、豆甾醇、豆甾 7 烯 3β醇。
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Compound 9 is glycosylated in the presence of TMSOTf with rhamose-derived trichloroacetimidates to provide target trisaccharide Saponin 1, oleanolic acid 3-yl-2,4-di-O-a-L-rhamnopyranosyl -p-D-glucopyranosideCoumpond 18 is prepared with oleanic acid and Bromide 11 through phase-thansfer catalysis glycosylation manner.
三糖皂苷Saponin 1是以葡萄糖齐墩果酸皂苷为起始原料,用BBTZ(1-苯甲酰苯并噻唑)选择性保护葡萄糖3′,6′-羟基得到化合物9,然后以化合物9为糖基受体,进行一步糖苷化可以在化合物9的2′,4′-羟基上同时引入两分子鼠李糖,最后脱掉所有的保护基得到目标化合物Saponin1。
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The common building block of them was synthesized by firstly glycosylation of an appropriately protected glucose with diosgenin, then introduction of a rhamnosyl residue to the 2-OH at Glu, finally freeing the 4-OH at Glu by selectively benzoylation of 6-OH.
我们先将适当保护的葡萄糖接在薯蓣甙元上,然后选择性地保护葡萄糖的 3 位羟基,在 2 位上引入一个鼠李糖,接下来选择性地保护葡萄糖的 6 位羟基,得到了上面三个皂甙的共同合成子。
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The common building block of them was synthesized by firstly glycosylationof an appropriately protected glucose with diosgenin, then introduction of a rhamnosyl residue to the 2-OH at Glu, finally freeing the 4-OH at Glu by selectively benzoylation of 6-OH.
我们先将适当保护的葡萄糖接在薯蓣甙元上,然后选择性地保护葡萄糖的3位羟基,在2位上引入一个鼠李糖,接下来选择性地保护葡萄糖的6位羟基,得到了上面三个皂甙的共同合成子。
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Two oligosaccharides, a hexasaccharide fragment of group E Streptococcus polysaccharide and a tetrasaccharide repeating unit of E. coli O7: K98: H6, consisting of α-(1→2)-and α-(1→3)-linked rhamnose backbones were synthesized in a regio-and-stereoselective manner.
以三氯乙酰亚胺酯为供体,不保护或部分保护的糖为受体,成功地合成了以α-(1→2)-和-α(1→3)-交替连接的鼠李糖为主链的GroupE Streptococcus六糖和E.coli O7:K98:H6四糖。
- 更多网络解释与鼠李三糖相关的网络解释 [注:此内容来源于网络,仅供参考]
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algin:褐藻胶
三种主要多糖,褐藻胶(algin) 、褐藻糖胶(fucoidan) 和海带淀粉(laminaran)的总含量大于20%. 褐藻糖胶是由鼠李糖、岩藻糖、木糖、甘露糖、半乳糖、葡萄糖、葡萄糖醛酸、硫酸根基蛋白质构成的复合物.
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Rha rhamnose:鼠李糖
吡啶Py pyridine | 鼠李糖Rha rhamnose | 三乙胺Ser triethyl amine
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gentianose:龙胆三糖
蔗糖(sucrose) 葡萄糖,果糖 甘蔗、甜菜乳糖(lactose) 葡萄糖,半乳糖 牛奶龙胆三糖(gentianose) 果糖,2分子葡萄糖 龙胆属某些种棉子糖(raffinose) 半乳糖,葡萄糖,果糖 棉籽甘露三糖(manneotriose) 葡萄糖,2分子半乳糖 木蜜鼠李三糖(rhamninose) 乳糖,
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rhamninose:鼠李三糖
海藻糖(trehalose) 葡萄糖,果糖鼠李三糖(rhamninose) 果糖,2分子葡萄糖水苏糖(stachyose) 果糖,葡萄糖,2分子半乳糖 水苏属某些植物3. 多聚糖类(polysaccharides) 简称多糖. 由10个以上单糖分子缩合而成. 通常由几百到几千个单糖基组成.
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rhamnitol:鼠李糖醇
rhamninose鼠李三糖 | rhamnitol鼠李糖醇 | rhamnogalactoside鼠李半乳糖苷