- 更多网络例句与高槟榔碱相关的网络例句 [注:此内容来源于网络,仅供参考]
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Methods Wistar rats were fed with highfructose diet for 12 weeks to induce Type 2 diabetes meilitus. Forty Wistar rats were randomly divided into 5 groups: a control group; a diabetic group; and a low (1 mg/kg), medium (5 mg/kg), or high (10 mg/kg) dose of arecoline groups.
采用高果糖饲料饲养Wistar大鼠12周制备2型糖尿病大鼠模型,40只实验动物随机分为5组:对照组、模型组、模型+1 mg/kg槟榔碱组、模型+5 mg/kg槟榔碱组、模型+10 mg/kg槟榔碱组。
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Results(1) Insulin secretion and mRNA levels of PDX1 were significantly decreased in rats with Type 2 diabetes meilitus compared with the control group.(2) Compared with the diabetic group, insulin secretion and mRNA levels of PDX1 were significantly increased in the medium and high dose of arecoline groups.
结果:(1)高糖作用引起Wistar大鼠胰腺β细胞PDX1 及胰岛素mRNA 的表达水平显著下降(P<0.01);(2)1 mg/kg和5 mg/kg槟榔碱处理能显著上调高糖喂养Wistar大鼠胰腺β细胞PDX1与胰岛素mRNA表达水平(P<0.05,P<0.01)。