髓鞘发生

基本解释 (translations)

myelogenesis  ·  myelogeny

与髓鞘发生相关的网络例句 [注：此内容来源于网络，仅供参考]

An infectious viral disease occurring in dogs, characterized by loss of appetite, a catarrhal discharge from the eyes and nose, vomiting, fever, lethargy, partial paralysis caused by destruction of myelinated nerve tissue, and sometimes death.

犬热病发生在狗身上的一种传染性病毒引起的疾病，主要特征是：无食物欲，眼鼻处有黏液，呕吐，发烧，昏睡，由于有髓鞘的神经组织受到损害而部分麻痹，有时会导致死亡

Objective To report two patients with demyelinating encephalopathy after having peppery spicy chafing dish,and study the possible mechanism of it.

目的 报告2例食用麻辣火锅后发生的脱髓鞘脑病，并探讨其可能发病机制。

The authors stress that they cannot prove whether antibodies against MOG and MBP have demyelinating capacity or whether they represent an epiphenomenon of myelin destruction.

作者强调，他们不能证明抗MOG和抗MBP抗体是否具有使髓鞘脱失的能力，或它们是否表示髓鞘受到破坏的现象，作者表示，抗MOG和抗MBP抗体的分析对于临床上出现分离症状的患者而言，是迅速、低廉，和精确的早期临床预测法，可以预测多重硬化症的发展，而这项研究结果对于咨询和推测发生第一次髓鞘脱失之患者是否患有多重硬化症，是相当重要的。

Neural cell adhesion molecule L1, discovered in the 80s, is one of the matters that can promote nerve regeneration. It can mediate the interaction of cell-to-cell and cell-to-matrix, take great efforts on neurite outgrowth and fasciculation, migration of neural cells, formation of the myelin, structure of neural trace, transmembrane signal transduction, inhibiting apoptosis of neural cells, even on immune system and formation of the tumor. Li is discovered on the mouse's Cerebellar membrane primarily. Thereafter, it also is found in post- mitotic neurons, pre- and non-myelinating Schwann cells and so on.

神经细胞粘附分子L1（L1）是80年代发现的具有促进神经再生作用的物质，它能介导神经细胞与神经细胞之间的粘附，在神经轴突的生长、聚集，神经细胞的转移，纤维髓鞘的形成，神经通路的构建及信号的转导，抑制神经细胞的凋亡甚至在免疫系统、肿瘤的发生等方面均具有非常重要的作用。L1最初是从小鼠的小脑膜中发现，后来发现在有丝分裂后的神经元，髓鞘形成前及非形成髓鞘的雪旺细胞等组织中同样存在。

We observed highly significant changes of fiber orientations at regions that correspond to the superior longitudinal fasciculus during the first 5 years.

我们发现在出生后的开始5年，上纵束相关纤维束的区域定向发生明显改变。这个结果说明上纵束的轴突和髓鞘发育很慢，而这个区域被认为和语言功能相关。

Histomorphologic changes of myelin sheath might contribute to the development of anxiety symptom in morphine-dependent rats suffered from withdrawal.

结论杏仁核中髓鞘结构的改变可能是吗啡依赖戒断后焦虑发生的病理学基础之一。

OLIG2 is a transcription factor which could regulate the transcription of many oligodendrocyte/myelination related genes, and its expression level also was down-regulated in schizophrenia subjects. Therefore, OLIG2 is mostly like to be a risk gene of schizophrenia.

OLIG2是一个能够调控下游许多与少突触细胞/髓鞘发生相关的基因表达的转录因子，且OLIG2的表达水平在精神分裂症患者体内也明显下降，因此，OLIG2极有可能是精神分裂症的致病基因。

Short-term enriched environment has positive effects on the white matter and myelinated fibers in the white matter in 24-month male rats.

提示短期丰富生存环境可能促使老年雄性大鼠白质内已经发生脱髓鞘改变的有髓神经纤维出现髓鞘再生。

At midgestation, cortical axonal tracts in the emerging white matter were PSA-NCAM+, but they were not yet myelinated, based on the lack of myelin basic protein immunoreaction.

妊娠中期发生的皮质轴突束是PSA-NCAM+的，但是还没有髓鞘，因为缺乏髓磷脂碱性蛋白的免疫反应。

While the tissue spaces surrounding a few blood vessels wasAl and Fg positive,no Al or Fg positive cells were observed.In antemortem injurygroup,diffuse subarachnoid hemorrhage,cerebral edema,swelling or pyknotic neu-rons could be observed.The axons showed irregular swelling and disconnection at1～3h,marked swelling and disconnection at 6h,and retraction ball at 15h whichwas more remarkable at 24h after injury.The space between myelin sheaths andaxons was increased at 3～6h after injury.Tortuous and wavelike myelin sheathswhich adhered on axons incompletely,or even peeled off could be found from 15hto 24h after injury.Perinuclear lysis of Nissl bodies began at 24h after injury.Thenumber of GFAP positive cells in cerebrum and brain-stem increased significantlyfollowed by decrease,and then increased again,but the time courses of the changesin different areas of brain were not same.Al and Fg positive neural cells,mainlysurrounded blood vessels,with diffuse or peripherally distributed positive matter incytoplasm could be observed at 0.5h after injury.The number of Al or Fg positivecells and the intensity of immunoreaction increased with the time of injury.The areaof SYN positivity in medulla oblongata and pons decreased notably 3～6h afterinjury,then return to normal levels and continued to 24h after injury.

生前损伤组，可见广泛蛛网膜下腔出血，脑组织水肿，神经细胞肿胀，晚期神经元固缩；伤后1～3h见部分神经轴突不规则增粗、断裂，伤后6h断端膨大，伤后15h可见收缩球，至伤后24h更为明显；伤后3～6h可见部分神经髓鞘与轴突之间的间隙增宽，伤后15h髓鞘明显曲折，不完全附着在轴突两侧，甚至剥脱，持续到伤后24h；核周尼氏体减少在伤后24h才开始出现；同一部位的GFAP阳性细胞数目随损伤时间发生改变，先增多（最早在伤后0.5h），达到高峰后减少，其后又有增多趋势，但不同部位的GFAP阳性细胞数目增减的时间过程不尽相同，同时，大脑中的GFAP阳性细胞数目也有改变；伤后0.5h，可在脑干组织中见到Al和Fg阳性神经细胞，主要位于血管周围，阳性物在胞浆中呈弥散性分布，但部分细胞的阳性物仅分布于靠近胞膜的胞浆中而呈环状，随损伤时间延长，阳性细胞数目增多，反应强度增加；伤后3～6h，延髓及桥脑中的SYN阳性物面积减少，其后恢复到正常水平，并持续到伤后24h。

与髓鞘发生相关的网络解释 [注：此内容来源于网络，仅供参考]

extensor muscle：伸肌

铅会引起周边神经麻痹、运动神经元病变,因在神经细胞内铅或毒性代谢物聚积会引起节段性脱髓鞘(segmental demyelination)导致手脚酸麻、肌肉无力、感觉异常、神经传导速率减低等症状. 铅中毒最易影响伸肌(extensor muscle),严重时造成垂腕、垂足、甚至脑病变而致死. 于婴幼儿之中枢神经受影响会导致"铅脑症"发生.

myelin figure：髓鞘样结构

当然,如损伤或水肿严重,则亦可发生继发性形态改变如出现肿浆膨出、微绒毛变短甚至消失、细胞膜基底变平乃至细胞膜破裂等. 在某些较严重的损伤时还可出现细胞膜的螺旋状或同心圆层状卷曲,形成典型的髓鞘样结构(myelin figure)

saltatory conduction：跳跃式传导

构成髓鞘主要成分的脂质是不导电或不允许带电离子通过的,而局部电流也只能发生在相邻的郎飞结之间,其外电路要通过髓鞘外面的组织液,这就使动作电位的传导表现为跨过每一段髓鞘而在相邻的郎飞结处相继出现,这称为兴奋的跳跃式传导(saltatory conduction).

medullar primordium：髓质原基

髓磷脂myelin | 髓质原基medullar primordium | 髓鞘发生myelinogenesis

myelinogenesis：髓鞘发生

髓质原基medullar primordium | 髓鞘发生myelinogenesis | 髓鞘形成myelination

myelogenesis：髓鞘发生

myelofibrosis 骨髓纤维变性 骨髓纤维化 骨髓纤维化症 | myelogenesis 髓鞘发生 | myelogenicosteopathy 骨髓性骨病

ss myelogenetic law：费莱西希髓鞘发生定律

flaw 缺点 | ss myelogenetic law 费莱西希髓鞘发生定律 | flesh 人性

Flechsigs myelogenetic law：弗莱希西希髓鞘发生定律

Flechsigs field 髓鞘生成区 | Flechsigs myelogenetic law 弗莱希西希髓鞘发生定律 | flexing 屈曲

Flechsig's myelogenetic law：弗莱希西希髓鞘发生定律

Flechsig's fasciculus 前固有束 Flechsig's field 髓鞘生成区 | Flechsig's myelogenetic law 弗莱希西希髓鞘发生定律 | flexing 屈曲

Flechsig's myelogenetic law：费莱西希髓鞘发生定律

flaw 缺点 | Flechsig?s myelogenetic law 费莱西希髓鞘发生定律 | flesh 人性