重要的新发现

基本解释 (translations)

breakthroughs

与重要的新发现相关的网络例句 [注：此内容来源于网络，仅供参考]

Among those hydrogenbonding residues, Tyr119, His227, Asn392 and Leu451 could form hydrogen bond with the benzofuran inhibitots and Tyrl07, Asn175, Thr211 and Asp412 were newly discovered hydrogen-bonding residues, which were highly conserved residues across the NMT family and would play an important role in the design of NMT inhibitots with novel chemical scaffold.

CaNMT活性位点发现有两个氧键作用区域，其中Tyrll9，His227，Asn392和Leu451是与已有抑制剂的氢键结合位点，Tyr107，Asn175，Thr211和Asp412是新发现的氢键结合位点，而且在NMT家族中高度稳定，它们对设计新结构类型的CaNMT抑制剂具有重要作用。

It has been pointed out that a major contribution made by the book is the find and research of the archives of Mathew Boulton,a businessman who was closely involved in the story of Paktong during the late eighteenth century.

该书的主要学术贡献在于发现了英国 18世纪后期著名工业家马修·波尔顿的档案资料并做了深入地研究，从而找到了一批重要的新史料，使白铜史上的一些疑难问题得以澄清。

The great potentials for exploration of litho-stratigraphic reservoirs do not appear until new methods and technologies have been applied and in-depth understandings have been gained. In recent two or three years, big discoveries have been made in Jilin oilfield, in which 80 percent of reserves are found in some areas of thin sand-shale interbedding of its delta front. There still exist petroleum potentials amounting to 6×10^8 t for exploration in this area, especially in southern Songliao basin where the litho-stratigraphic traps will be more important domains and deserve extra attention. Hence, geologically speaking, this study on the hydrocarbon accumulation of litho-stratigraphic reservoirs in Songliao basin is of vital significance to exploration of the southern Songliao basin.

但通过新方法、新技术的应用和地质认识的不断深入，岩性－地层油气藏展现出了较大的勘探潜力，吉林油田近2-3年来的大发现和新增储量的80％是在有一定面积的三角洲前缘薄互层中获得的，在这个领域中仍有6×10^8t的石油资源有待勘探，特别是松辽盆地南部地层－岩性圈闭是未来油气勘探的重要领域，具有进一步解剖研究和勘探价值，因此，对松辽盆地岩性－地层油气藏成藏规律进行研究，对于松辽盆地南部勘探有着十分重要的意义。

First,we have discovered stone artefacts in caves, which have similar features to that were broadly scattered in laterite terraces in Bose basin(0.8 Ma B.P),next study on deposits and fauna will be hopefully contributed to document paleoenvironmental background of early human;Second,early human fossils,Gigantopithecus and mammalian fossils unearthed in Mohui cave provide new evidence of early human origin; Third,after our scientific excavation in Fengshudao site in Bose basin, we have found five pieces of bi-face LCT with 10 tektites and nearly 100 stone artefacts form original laterite deposit.This important discovery is very answerable to international question about stratigraphic suspect of LCT; Fourth, abounding mammallian fossils with human fossils and remains from early Pleistocene to Holocene have been uncovered after systematically excavation in marginal cave of Bose basin.These discoveries are significant to the study on human evolution and establishment of sequence of Quarternary biological-stratigraphic in southern China.

首先，我们在百色盆地边缘洞穴堆积物中，发现与百色盆地内网纹红土阶地（0.8 Ma ）类型相似的石制品，通过对堆积物及其包含动物群的研究有望对解决早期人类生存环境背景作出贡献；其次，在么会洞发现了早更新世早期大约1.8 Ma 的人类化石、巨猿化石和丰富的哺乳动物化石，为解决早期人类起源提供了新的证据；再次，在百色盆地枫树岛旧石器时代遗址，通过科学发掘，从原生地层中发现五件与玻璃陨石共生的手斧，以及近百件其它类型的石制品，解决了目前国际学术界普遍关注的百色手斧的层位问题，为进一步确定百色旧石器的时代奠定了基础；另外，通过对百色盆地边缘洞穴的系统发掘，发现了自早更新世早期至全新世以来不同时代的大量哺乳动物化石，同时还发现中更新世晚期--晚更新世早期和全新世的人类化石和石制品，对研究人类演化、建立华南第四纪生物地层序列具有重要的科学意义。

To our knowledge, this was first study about AQPs expression in ovine adult lung and ovine fetal lung.

我们的新发现暗示AQPs参与了长妊娠期种属胎肺液体的产生与吸收，对胎肺的发育也有重要的影响。

Protein transduction of VP22, a unique biology phenomena with significant theoretical meanings and potential application value, was discovered in recent years.

蛋白转导是近年来生命科学领域的一项具有重要理论意义和潜在应用价值的新发现。

These compounds are of substantial interest both inviewpoints of theory and practical applications, mainlyunder the stimulus to achieve synthetic models either foractive sites of iron-sulfur proteins or for transitionmetal catalysts. This thesis describes the synthesis, structures andconformations of 51 new iron-sulfur cluster complexes,which have been characterized by elemental analysis andstandard spectroscopic methods. In addition, single-crystalX-ray diffraction analyses were performed for 4 representa-tive new compounds. Reactivities of μ-〓 with mono- and di- Grig-nard reagents derived intermediates toward various organicelectrophilic substrates were studied, along with complexa-tion of arynyl-containing iron-sulfur clusters by 〓Thus, several bridged, non-bridged, monomeric, dimeric,homonuclear, heteronuclear iron-sullfur and iron-sulfur co-balt-carbon cluster complexes were synthesized. A novelreaction and convenient route for the synthesis in highyield of tetranuclear iron complexes 〓 containing atetracoordinated sulfur atom was discovered, whereas aplausible mechanism based on experimental results was propo-sed for the formation of the new cluster type.

鉴于有机铁硫原子簇化学在基础理论发展和应用方面的重要意义，因此我们开展了这一课题的研究，并取得以下主要成果： 1、本文共合成了51个新有机铁硫及含钴碳簇基的有机铁硫原子簇配合物，除用元素分析，NMR，IR，MS法表征其结构和构象外，还用X-光衍射技术测得四个代表性配合物的单晶结构和构象； 2、我们业已发现炔基Grignard试剂同〓可形成一种&开环&与&闭环&中间物的平衡混合物，研究该平衡混合物同各种亲电试剂的反应； 3、研究发现了一种可高产率地形成〓含〓四配位硫挛合簇的新化学反应并对此反应提出了—种有趣的反应机理； 4、首次由1，4-二溴丁烷双Grignard试剂与〓制得一种新型铁硫簇双硫阴离子活性中间体，并进而研究了它的亲核反应性能； 5、找到了通过〓的光化学反应来合成簇合物〓-〓的一条有实用价值的新路线。

Several anti-tumor cell lines and carbonic anhydrase Ⅱ model were established. More than 10000 compounds and extracts from plants were screened using these models and about 10 compounds showed strong inhibitory activities. Two species of plants Inula helianthus-aquatica and Saussurea deltoidea were chosen to investigate chemical and bioactivity constituents based on the results of screening of extracts and fractions. 58 compounds were isolated and identified from these two plants, 6 compounds were found to be new and 14 compounds showed anti-tumor activities. We also studied the anti-tumor mechanism of the compound bigelovin isolated from Inula helianthus-aquatica. Bigelovin was found with apoptotic activity against cell line U266 by lowering the amount of important transcription factor E2F-1 which inhibits the cell cycle at G0/G1 stage. Docking study on 7 natural new phenolic inhibitors of CA Ⅱ and 3D-QSAR study on 61 sulfonamide inhibitors of CA Ⅱwere also investigated. The calculated results were in good correlation with experimental results.

基于以上两种重要疾病和研究组方向，本论文工作开展了多个肿瘤细胞株和碳酸酐酶Ⅱ靶标模型的建立和筛选工作，累计筛选1万多个/次样品，发现10余个活性较强化合物；从粗提取物筛选结果中选取两种抗肿瘤活性强的菊科植物水朝阳旋覆花(Inula helianthus-aquatica)和三角叶凤毛菊进行了系统化学和活性成分研究，分离鉴定了58个化合物，发现6个新化合物和14个抗肿瘤活性化合物；通过合作对水朝阳旋覆花中活性较强的bigelovin进行了抗肿瘤作用机制研究，发现它可能是通过降低G2期重要的转录因子E2F-1，致使细胞周期阻滞在G0/G1期，引起多发性骨髓瘤U266细胞凋亡；开展了7个新的天然酚类CAⅡ抑制剂的对接研究和61个合成的系列磺酰胺类CAⅡ抑制剂的3D-QSAR分析，结果表明计算与实验一致。

The senior author, YIN Wen\|Ying suggested a new consideration on the higher taxa systematic of the Class Protura at the 20th International Congress of Entomology at Firenze, Italy in 1996. Only a brief abstract of this suggestion was published in the Proceedings of the Congress.

1996年第 2 0届国际昆虫学大会上，尹文英根据多年研究的新发现提出了原尾纲Protura分为 3目 10科的新建议，仅刊登在该次会议的论文摘要中，至今尚未能详细阐述重新分群的重要特征和分析。

While if we are emphasizing,countryside teachs course of study of teachers training school property, take seriously from sociological, anthropologic the communal sex problem that waits for a perspective to discuss rustic teacher, so, the new form that we can discover to the rustic teacher transmission to knowledge, discovery, creation and society are affected, also make the connotation of rustic teacher more rich thereby, such ability reveals the at the country important sense of rustic teacher, ability makes much appearance of form of rustic teacher development colorful, the society that finish is ideal, enjoy life happiness.

假如我们在强调乡村教师专业性质的同时，重视从社会学、人类学等视角探索乡村教师的公共性新问题，那么，我们就会发现乡村教师对知识的传播、发现、创造和社会影响的新形式，从而也使乡村教师的内涵更加丰富，如此才能彰显乡村教师之于农村的重要意义，才能使乡村教师发展形式多姿多彩，完成社会理想，享受人生幸福。

与重要的新发现相关的网络解释 [注：此内容来源于网络，仅供参考]

aftertaste：余韵

写下你对啜吸风味(flavor),酸性的质地(acidity),余韵(aftertaste)与醇度(body)的描述. 试验下一杯而且试著比较这几杯的风味. 在每杯咖啡都冷却了之后,常常有可能发现新的啜吸风味(flavor). 因此分别在咖啡仍温时及冷却至室温后两种温度来测试是很重要的.

HARD DISKS：(硬盘)

此项发现不但让人们对基本物理有进一步的了解,对改良计算机数据储存用的硬盘(hard disks)的"记录头"(recording head),以及发展储聚能源的新设计、开发新一代的能源转换装置等工业应用上十分重要.

Emotions：情感

实际上这些新发现的文本不仅重新指明"情感"(emotions)是自我实现中的重要因素,而且有助于解决这一复杂难解的术语的意义,关于其意义的争论已持续了很长时间.

microbicide：杀微生物剂

而在母体中新发现的这种糖化合物可能是一种"杀微生物剂"(microbicide)兼有杀精和杀灭微生物作用,对预防HIV感染可能具有重要作用. 母乳中这种新发现的糖化合物被称作刘易斯X(Lewis X),是一类在唾液和血液中也能发现的糖.

nicotinamide：烟碱

最近还发现,在实验系统中许多能够延长生命的蛋白都是NAD依赖性的. NAD的合成前体一直认为只有烟酸(nicotinic acid)和烟碱(nicotinamide). 然而最近,一条新的代谢途径被发现;并且,这个途径还可能有重要的作用.

Pythagorean：毕达哥拉斯

保守秘密的规矩遮掩了同时代的毕达哥拉斯(Pythagorean)同行们的活动,数学对他们来说是重要的东西,而且它的新加入者为他们关于宇宙秩序的新发现保密(在等级制度中,了解了关于无秩序状态的更深秘密的人会受到失去理性的成员的威胁).

Vivian：周慧敏

网易娱乐10月8日讯(图文/CFP) 周慧敏(Vivian)昨日(10月7日)在香港以"粉红大使"身份出席香港癌症基金会的"粉红革命"活动,提醒妇女及早发现乳癌的重要,近日有报道称Vivian将复出拍许鞍华的新戏,戏中与吴君如有大胆同性恋戏份,

Whitehall：怀特霍尔

查理斯.纳皮尔爵士(SirCharlesNapier)在1843年侵占信德(Sind)时,已能够向居于怀特霍尔(Whitehall)的主人发送一个单词的电报信息--罪过(我犯罪了). 整个地球已经能够用精致而全面的地图绘制出来;没有任何具有重要意义的新发现的地区被遗漏.

Scaffolds：脚手架

更重要的是使用"锚"来帮助学生发现新学习的必要,从而树立学习目标的重要性. 也就是说教学应该帮助学生在完整的真实情境中确认学习目标. 教师预先教授一些知识是为了提供帮助学生继续前进的资源和"脚手架"(Scaffolds).

Leibniz：莱布尼茨

自牛顿GM 莱布尼茨(Leibniz)发现微积分后,数学发展到一个新阶段. 英国数学界由于坚持几何方法而进展缓慢;欧洲大陆数学家却继续在分析方法上不断探索而迅速发展,进入数学分析的开拓时期. 达朗贝尔是重要的开拓者之一,其成就仅次与欧拉,