- 更多网络例句与酰化相关的网络例句 [注:此内容来源于网络,仅供参考]
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Study on the Crystallization Process of Labeled GL-7-ACA Acylase CA130 Complex 7β-bromoacetyl amino cephalosporanic acid (BA-7-ACA), an analog of glutaryl-7-amino cephalosporanic acid (GL-7-ACA), can inhibit and specifically alkylate GL-7-ACA acylase (CA130) from Pseudomonas sp. 130, forming a carbon-carbon bond between BA-7-ACA and the C-2 on indole ring of Trp-β4 residue of CA130.Here we reported that BA-7-ACA labeled CA130 (BA-C130) could self-catalyze the hydrolysis of BA-7-ACA during crystallization process. The hydrolysis was confirmed to be a reaction analogous to the one of GL-7-ACA by comparative MALDI-TOF (matrix-assisted laser desorption/ionization-time of flight) spectrometry analysis.
二、GL-7-AcA酰化酶CA130标记复合物的结晶过程研究溴乙酰氨基头孢烷酸(7β-bromoacetyl amino cephalosporanic acid,BA-7-ACA)作为戊二酰-7-氨基头孢烷酸(GL-7-ACA)的类似物,不仅能够抑制GL-7-ACA酰化酶CA130的活力,而且能通过在BA-7-ACA和CA130的β亚基第四位色氨酸吲哚环二位碳原子之间形成碳-碳共价键而将CA130特异的烷基化。
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Two kinds of water-soluble biomimetic chitosan derivatives with a phosphoramide linkage between glucosamine and choline were prepared through Atherton-Todd reaction under the mild conditions, including zwitterionic phosphorylcholine bound chitosan and acetyl-phosphorylcholine bound chitosan with positive charge. The interaction between chitosan derivatives and calf thymus DNA were inversigated by UV alsorption spectra and circular dichroism spectra.
采用Antherton-Todd反应制备了两种水溶性的磷酰化壳聚糖仿生衍生物:两性的N-磷酸胆碱磷酰化壳聚糖和带正电荷的N-乙基磷酸胆碱磷酰化壳聚糖,并用紫外吸收光谱和圆二色光谱研究了两种胆碱磷酰化壳聚糖衍生物与小牛胸腺DNA的相互作用。
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Methods Starting from 2-chloro-4-nitrophenol and 2- pyridine hydrochlorid, 3-chloro-4-(pyridin-2-ylmethoxy) aniline was obtained via etherization and reduction. The obtained aniline coupled with N-(4-chloro-3-cyano-7-ethoxyquinolin-6-yl) acetamide to give 4-[3-chloro-4-(2-pyridylmethoxy) phenylamino]-3-cyano-7-ethoxy-6-N-acetylaminoquinoline. And then it was deacetylated, followed by reacting with4- but-2-enoyl chloride to yield the target compound neratinib.
以2-氯-4-硝基苯酚和2-氯甲基吡啶为起始原料,经醚化、硝基还原得到3-氯-4-(吡啶-2-甲氧基)苯胺,3-氯-4-(吡啶-2-甲氧基)苯胺与3-氰基-6-乙酰氨基-7-乙氧基-4-氯喹啉反应得到3-氰基-6-乙酰氨基-4-[3-氯-4-(吡啶-2-甲氧基)苯氨基]-7-乙氧基喹啉,3-氰基-6-乙酰氨基-4-[3-氯-4-(吡啶-2-甲氧基)苯氨基]-7-乙氧基喹啉去乙酰保护基后,与-4-二甲氨基-2-丁烯酰氯经酰化反应得到ner-atinib。
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Except heptanoyl chitin, four of them,i.e.acetyl chitin,propionyl chitin,butyryl chitin and hexanoyl chitin,had high degree of substitution(from 1.5 to 2.0)and exhibited lyotropic liquid crystalline behavior and cholesteric phase.
文摘:四种羧酰化甲壳素即乙酰化、丙酰化、丁酰化和己酰化甲壳素在二氯乙酸溶液中均呈现胆甾型溶致液晶相。
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The effect of N-phosphoamino acids on plant cells'membrane permeability was investigated by osmotic method. It was found that in all N-phosphoamino acids, only some phosphoryl polar amino acids such as DIPPSer, DIPPThr, DIPPHis, DIPPAsp, DIPPGlu, DIPPAsn and free serine, threonine could increase the water permeability in plant cell membrane. For example, after 20min. treatment by 1. 5mM DIPPSer, the deplasmolysis time of onion cells was shortened 50%.
三、通过透性实验研究了N-磷酰化氨基酸对洋葱、豌豆等植物细胞膜水透性及溶质透性的影响,发现在所有的N-磷酰化氨基酸及自由氨基酸中,仅有部分N-磷酰极性氨基酸和自由的丝、苏氨酸对植物细胞膜上水透性有增强作用,如1.5mM N-磷酰化丝氨酸可使洋葱细胞质壁复原时间缩短一半以上。
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The main results and conclusions are as followings.1, The histone deacetylase inhibitors were used to feed the larve of the fly, and then the polytene chromosomes were observed under the microscope.
得到的主要结果和结论如下: 1,通过用去乙酰化酶抑制剂处理果蝇幼虫,观察果蝇多线染色体在热休克基因处的形态变化,发现去乙酰化酶抑制剂介导的乙酰化水平的升高可引起染色体结构的显著变化,推测乙酰化修饰不仅影响分子间的相互作用而且还可以影响染色体的高级结构。
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The yield reached 67.0% The medicinal and pesticidal activities of a part of the compounds have been measured .
在进行氨基酰化时,论文克服了该类嘧啶环上4位氨基在常规条件下不与芳香类和带有强吸电子基如三氯乙酰基酰化试剂发生反应的困难,通过采用在强碱性条件下进行酰化,得以成功。
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Methyl 6-acylnaphthalene from 2-methylnaphthalene was synthesized via acylation using acetic anhydride and propionyl chloride as the acylating agents with catalyst aluminum trichloride in homogeneous liquid phase system.
为制备重要的化合物2-甲基6-酰基萘,提高酰化产物的收率和纯度,以2-甲基萘为原料,分别研究了乙酸酐和丙酰氯为酰化剂时的酰化反应,对酰化反应的产物进行了GC、FT-IR和GC-MS表征;对酰化反应的影响因素进行了研究。
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Three methodsconventional direct acylation,acylation by phase transfer catalyst(PTC,and ionexchange-acylation were selected for the purpose of acetylating κ-carrageenan with 30kDa molecular weight.
选择常规直接酰化、相转移催化酰化和离子交换-酰化共3种方法对3万中等分子量的κ-卡拉胶进行了乙酰化反应。
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The kinetics of reconstitution of apoacylase with either 〓 or 〓 and the inactivation of the 〓 reconstituted enzyme by 1, 10-phenanthroline has been studied by following the substrate reaction continuously in presence of the metal ion or OP respectively. Although the native 〓-containing and the 〓-reconstituted enzymes have closely similar Michaelis constants and maximal velocities, the kinetics for both the inactivation by OP and the reconstitution of the apoenzyme with the metal ions differs considerably.
虽然钴重组的氨基酰化酶与天然含锌的氨基酰化酶在催化活性上比较相近,但两种酶在去金属失活动力学机制以及去金属失活的氨基酰化酶与两种金属离子重组复活的动力学过程均存在较大的差异,说明锌在氨基酰化酶中的作用比较复杂,并不能完全由钴替代。
- 更多网络解释与酰化相关的网络解释 [注:此内容来源于网络,仅供参考]
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acetylation value:乙酰化值
acetylating agent | 乙酰化剂 | acetylation value | 乙酰(化)值 | acetylation | 乙酰化作用
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acylate:酰化;酰化产物
actuator 驱动器;执行机构;激励器 | acylate 酰化;酰化产物 | acylation 酰化作用
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acylate:酰化产物
acylase酰基转移酶,酰酶 | acylate酰化产物 | acylated酰化了的
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acetylated monoglyceride:乙酰化甘油单[酸]酯,乙酰化单[酸]甘油酯
乙酰化磷酸双淀粉 acetylated distarch phosphate | 乙酰化甘油单[酸]酯,乙酰化单[酸]甘油酯 acetylated monoglyceride | 乙酰化 acetylation
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succinyl oxide:琥珀酰化氧,琥珀酰酐
succinyl CoA synthetase 琥珀酰CoA合成酶 | succinyl oxide 琥珀酰化氧,琥珀酰酐 | succinylcholine 琥珀酰胆碱,丁二酰胆硷
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acetylate:乙酰化,乙酰化产物
acetylvanilloyl乙酰基香草酰 | acetylate乙酰化,乙酰化产物 | acetylation乙酰化作用
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acetylate:乙酰化;乙酰化物
acetyl-glucosamine 乙酰氨基葡萄糖 | acetylate 乙酰化;乙酰化物 | acetylated fat 乙酰(化)脂肪
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acylation:酰化(作用)
酰化理论认为肺毛细血管壁通透性增强与光气的酰化作用(acylation)有密切关系. 光气为酰卤类化合物,活性基团是羰基(O=C),化学性质非常活泼,它与肺组织蛋白中的氨基、巯基、羟基等重要功能基团发生酰化反应,引起肺酶系统的广泛抑制,
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acetylated staple:乙酰化短纤维
acetylated phenolic fibre 乙酰化酚醛纤维 | acetylated staple 乙酰化短纤维 | acetylating viscose rayon 乙酰化粘胶人造丝
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acetylating viscose rayon:乙酰化粘胶人造丝
acetylated staple 乙酰化短纤维 | acetylating viscose rayon 乙酰化粘胶人造丝 | acetylator 乙酰化器