- 更多网络例句与软骨与骨的相关的网络例句 [注:此内容来源于网络,仅供参考]
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Material and MethodsRA Rabbit Model group: 15 early RA rabbits of the same weight and variety Control group:10 normal rabbits of the same weight and varietyMethods of making RA rabbit model:elect 15 normal rabbits of the same weight and variety, dissolve Ovalbumin in 0.9% sodium chloride solution, to make the solution of 20mg/ml concengtration, blend the same quantity of complete Freund′s Adjuvant equably ,inject the mixed solution into endermic tissue of the rabbit′s scapular section, making the rabbits allergic, inject 1 ml of the mixed solution to one rabbit every time, inject 1 ml of the mixed solution in 5 different places of the rabbit′s scapular section, inject the rabbit one time every week,inject 3 weeks continuously,it turned out to be that the rabbits will be allergic, inject Ovalbumin blent with the 0.9% sodium chloride solution into the knee joint cavity of the rabbits in the fourth week, 5 mg Ovalbumin every knee joint cavity,two knees of every rabbit of the 15 rabbits are both injected,the arthrosis diameter and the exterior temperature of the knees will be added obviously in 24 hours,and they will drop gradually,at the time of the 14th or 21th day, the arthrosis diameter and the exterior temperature of the knees will get to the balance time,the incidence rate of RA is 100%.after the RA model succeeds,it is the early time of RA from the first week to the fourth week,after the fourth week,it is the late time of RA, the cartilage of the femoral condyle and the subchondral bone cortices will be changed unrecoverily.
资料与方法RA模型组:早期RA家兔模型15只,品种及体重接近。对照组:正常家兔10只,品种及体重接近。RA家兔模型制作方法:选取15只成年家兔,体重、品种接近,将卵蛋白溶解于生理盐水,配成浓度为20mg/ml的溶液,与等量完全弗氏佐剂混匀,注入家兔肩胛区皮下致敏,每只家兔每次注射1ml,于肩胛区5个不同区域注射,每周一次,连续注射3周而致敏,第4周向膝关节腔注射卵蛋白生理盐水溶液,每只关节腔注射5mg卵蛋白,15只家兔膝关节全部注射,24h内此关节直径和表面温度大幅度上升,以后缓慢下降,至14~21d达到平台期,发病率达100%。造模成功后第1~4周为早期改变,第4周以后出现不可逆的关节软骨及骨破坏。采用高频超声对RA模型组与对照组的膝关节髌上囊液体厚度、滑膜及股骨髁软骨厚度及软骨下骨皮质的回声情况进行对比观察。结果RA组模型组膝关节髌上囊积液及滑膜的厚度明显厚于对照组,其股骨髁软骨的厚度与对照组相比无明显差异,其软骨下骨皮质与对照组相比无明显改变。
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After 24 weeks,the operation area of group A was more smooth,and the surrounding normal cartilage naturally straight flush,transparent form new cartilage,subchondral bone formation in good condition;Group B restoration surgery the basic integrity of the cartilage tissue, center is not yet fully integrated,there was slight depression;CollagenⅡimmunohistochemistry of cartilage that was new brown area.Group C has no formation of articular cartilage.The growth and the intergration of subchondral bone of group A and B were better.
术后24周取材,见A组山羊手术区关节表面较为光滑,与周边正常软骨自然连续平齐,透明的新生软骨组织形成,软骨下骨形成完好;B组山羊手术区修复的软骨组织基本完整,中心部位仍未完全融合,有微小凹陷;Ⅱ型胶原免疫组化示新生软骨组织呈棕黄色。C组术区关节凹陷,无关节软骨组织形成。A组和B组,软骨下骨的生长及与周围组织的结合均较好,无植入物脱落现象的发生。
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After 12 weeks,the result showed the operation area of group A articular surface was smooth,with the surrounding normal cartilage naturally straight flush, transparent form new cartilage tissue;Group B restoration surgery the basic integrity of the cartilage tissue,but the center of many not fully integrated,there is slight depression,surface wear,good subchondral bone formation;control group, depression joint operation areas,non-articular cartilage formation,such as lack of bone joints.
术后12周取材,A组修复区可见部分软骨样组织,关节软骨无磨损,修复的软骨呈白色半透明外观,与周围正常关节软骨有连续性,可见一明显的凹陷,无明显软骨下骨外露;B组修复区也可见部分软骨样组织,关节软骨在修复区可见磨损,软骨呈白色不透明外观,软骨下骨形成较好;空白对照组术区关节凹陷,无关节软骨组织形成,关节下骨缺如。
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Then the cultivated chondrocytes were embedded in fibrin glue fused on spongy bone, covered with priosteal flap; the complex was used to repair the femoral trochlea osteochondral defect which size is 3mm × 4mm × 4mm made in rabbit knee joint.
在A组的每只兔子的一侧膝关节股骨滑车部人为造成3mm×4mm的骨软骨缺损,骨刀切除软骨下骨到髓腔渗血为止(厚约4mm),压迫后FG止血;取髂骨骨块,并尽可能保留松质骨,取下的骨块用PBS反复清洗,以除去血细胞,将松质骨填充在骨缺损处,松质骨面朝向关节腔,高度与周边软骨下骨齐平,把骨膜片生发层朝向关节腔,用无创伤缝合线缝合在周边的软骨或滑膜组织上;向EP管中加入1/2悬液体积的FG主体胶溶液并混匀,再与主体胶等体积的催化剂溶液一同注射入骨膜与骨块密闭的腔隙中;同理处理另一侧膝关节。B组处理与A组相比只是不加入软骨细胞;C组造成骨软骨缺损,FG覆盖创面后单纯用骨膜修复缺损。
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MRI of 36 cases with acute cartilage injury of knee confirmed by arthroscopy and arthrostomy were retrospectively analyzed, with emphasis on articular cartilage and subchondral lesion.
分析其中36例经关节镜或手术证实关节软骨损伤患者的膝关节MRI所见,着重观察关节软骨和软骨下骨的改变,并与关节镜和手术结果对照分析。
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Mri of 36 cases with acute cartilage injury of knee confirmed by arthroscopy and arthrostomy were retrospectively analyzed, with emphasis on articular cartilage and subchondral lesion.
分析其中36例经关节镜或手术证实为关节软骨损伤患者的膝关节mri所见,着重观察关节软骨和软骨下骨的改变,并与关节镜和手术结果对照分析。
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Results:(1) FSN can inhibit secondary joints swelling and multi-arthritis evidently, improve the whole condition of rats; at the same time, it can also lighten the synovial inflammation and hyperplasia of lesion joints distinctly, and prevent the joint cartilage and bone from destruction; the collective efficiency of FSN is better than TWP.(2) FSN can raise AA rats low LTT of spleen to normal nearly, remedy the disorder of Th / Ts and Thl / Th2 cells balance in peripheral blood, restrain exorbitant TNF- a ? IL-1 produced by PM O , thereof exert anti-inflammatory and immunoregulation effect.(3) Inside the lesion joints, FSN can depress abnormal hyper-expression of TNF- a mRNA and NF-kB in synovial tissues, as well as advance the expression of Caspase-3 (a proteolytic enzyme of apoptosis), reduce synovial immflamination and proliferation.(4) FSN can lower the expression of VEGF in synovial tissue,reduce neogenetic veins, so inhibit the growth of pannus tissue and the damage of cartilage and bone by that.(5) The above effect of FSN are in proportion to its dosage.Conclusions: FSN has inhibitory effects on symptom and condition of experimental RA, which is better than TWP as a whole.
结果:(1)FSN有明显的抗炎作用,可显著抑制AA大鼠足跖肿胀与多关节炎,改善大鼠的全身情况,同时明显减轻病变关节滑膜炎症与增生,防止关节软骨及骨质的破坏,其综合作用优于TWP;(2)FSN还能使AA大鼠低下的脾LTT恢复至接近正常,纠正外周血中T细胞亚群Th/Ts及Th1/Th2平衡紊乱,抑制大鼠PHφ过高的TNF-α、IL-1分泌,而发挥抗炎和免疫调节作用;(3)在病变关节局部,FSN能显著抑制AA大鼠滑膜细胞异常增高的TNF-αmRNA的表达,降低滑膜组织中NF-kB表达,并增加凋亡蛋白酶Caspase-3表达,从而抑制滑膜的炎症与增殖;(4)FSN还可下调滑膜组织中VEGF表达,减少血管新生,由此抑制血管翳的形成及其对软骨和软骨下骨的侵蚀;(5)FSN的上述作用皆呈现一定的量效依赖关系,高剂量组作用优于低剂量组。
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FSN can raise AA rats low LTT of spleen to normal nearly, remedy the disorder of Th/Ts and Th1/Th2 cells balance in peripheral blood, restrain exorbitant TNF-α、IL-1 produced by PMφ, thereof exert anti-inflammatory and immunoregulation effect.(3) Inside the lesion joints, FSN can depress abnormal hyper-expression of TNF-αmRNA and NF-kB in synovial tissues, as well as advance the expression of Caspase-3 (a proteolytic enzyme of apoptosis), reduce synovial immflammation and proliferation.(4) FSN can lower the expression of VEGF in synovial tissue, reduce neogenetic veins, so inhibit the growth of pannus tissue and the damage of cartilage and bone by that.(5) The above effect of FSN are in proportion to its dosage. Conclusions: FSN has inhibitory effects on symptom and condition of experimental RA, which is better than TWP as a whole.
结果:(1)FSN有明显的抗炎作用,可显著抑制AA大鼠足跖肿胀与多关节炎,改善大鼠的全身情况,同时明显减轻病变关节滑膜炎症与增生,防止关节软骨及骨质的破坏,其综合作用优于TWP;(2)FSN还能使AA大鼠低下的脾LTT恢复至接近正常,纠正外周血中T细胞亚群Th/Ts及Th1/Th2平衡紊乱,抑制大鼠PMφ过高的TNF-α、IL-1分泌,而发挥抗炎和免疫调节作用;(3)在病变关节局部,FSN能显著抑制AA大鼠滑膜细胞异常增高的TNF-αmRNA的表达,降低滑膜组织中NF-kB表达,并增加凋亡蛋白酶Caspase-3表达,从而抑制滑膜的炎症与增殖;(4)FSN还可下调滑膜组织中VEGF表达,减少血管新生,由此抑制血管翳的形成及其对软骨和软骨下骨的侵蚀;(5)FSN的上述作用皆呈现一定的量效依赖关系,高剂量组作用优于低剂量组。
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With this suspension suture technique, using the osteocartilaginous junction as a anchor provided the optimal position of the nasal tip and long-term nasal tip stability.
在闭合切口下,利用鼻背软骨与骨结合部的软骨作为固定锚着点的悬吊法上提鼻尖方法远期效果良好、稳定,操作简便、易行。
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Evaluate MRI representation:(1) segregation condition: transfixation band, segregation between cartilage and bone, segregation between bone and bone;(2) four stages of pathologic classification based on MRI signal character;(3) texture in weight bearing zone;(4) add Bone Marrow Edema score and joint effusion score as stasis index.
术前MRI评估:(1)股骨头内分离情况:贯穿带、软骨与骨分离,软骨下骨与骨分离;(2)股骨头内信号的病理分期;(3)冠状正中位的髋臼负重区下结构;(4)将股骨头骨髓水肿评分和关节积液评分相加记为关节的瘀积指数。
- 更多网络解释与软骨与骨的相关的网络解释 [注:此内容来源于网络,仅供参考]
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articular cartilage:关节软骨
1.关节软骨 关节软骨(articular cartilage)为关节表面的薄层透明软骨,表面光滑,附有滑液,可减小关节运动时的磨擦力. 关节软骨与一般的透明软骨有一定差异,表层的细胞较小,单个分布,深层的细胞较大,成行分布,近骨部的软骨基质钙化,
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articular cartilage:软骨
1.关节软骨 关节软骨(articular cartilage)为关节表面的薄层透明软骨,表面光滑,附有滑液,可减小关节运动时的磨擦力. 关节软骨与一般的透明软骨有一定差异,表层的细胞较小,单个分布,深层的细胞较大,成行分布,近骨部的软骨基质钙化,
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facial line:面线:连接鼻点和颏点的直线. 见height项下
cricoclavicular line 环(状软骨)锁(骨)线:从喉头环状软骨到腋前线向上投射与锁骨相交点的连线 | facial line 面线:连接鼻点和颏点的直线. 见height项下 | Farre's white line Farre白线:卵巢系膜附着于卵巢门的界线
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osteochondritis:骨软骨炎
儿童时期发生于骨骺或骨突部分的缺血性坏死又称骨软骨炎 (osteochondritis) . 股骨头骨骺缺血坏死( osteochondrosis of femoral head )又称 Legg-Perthes 病,是较常见的儿童骨软骨炎,发病与儿童期股骨头骨骺血供较单一有关,外伤是主要致病因素.
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quadrate:方骨
3.颅骨通过方骨(quadrate)与下颌连接,这种连接方式称自接型(autostylic). 初生颌(腭方软骨和麦氏软骨)趋于退化,由其外包的膜性硬骨(前颌骨、上颌骨和齿骨等)组成的次生颌,代为执行上、下颌的功能. 鲵螈类因颧骨(jugal)和方轭骨(quadratojugal)消失,
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Sesamoid cartilages:籽骨 在上方与下方外侧软骨之间靠外侧部分发现的小软骨
Scroll area 卷动区 下方外侧软骨外侧脚与上方外侧软骨之间联结处,可以反... | Sesamoid cartilages 籽骨 在上方与下方外侧软骨之间靠外侧部分发现的小软骨. | Supratip area 鼻尖上区域 刚好在鼻尖上方和鼻背下方之间...
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ceruminous gland:聹腺
外耳道的外侧段为软骨部,内侧段为骨部,表面覆以薄层皮肤,软骨部的皮肤内有大汗腺,称耵聍腺(ceruminous gland),腺体的分泌物称耵聍. 皮下组织很少,深部与软骨和骨紧密相贴. 鼓膜(tympanic membrane)为半透明的薄膜,分隔外耳道与中耳鼓室.
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cleithrum:匙骨
硬鳞鱼及肺鱼的软骨肩带开始有膜原骨,每侧至少有锁骨和匙骨(cleithrum)加入. 多鳍鱼的肩带显示出软骨原骨的比例减少,膜原骨的比例加大,计有锁骨、匙骨、上匙骨、后匙骨及后颞骨. 2.四足类:在最古的坚头类中,如始螈(Eogyrius)尚有后颞骨连于匙骨与头骨之间,
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epiphysial cartilage:骺软骨
骨干与骺相邻的部分称于骺端(metaphysis),幼年时保留一片软骨,称骺软骨(epiphysial cartilage),骺软骨细胞不断分裂繁殖和骨化,使骨不断加长. 成年后,既软骨骨化,骨干与骺融为一体,其间遗留一骺线(epiphysial line). 2.短骨(short bone)形似立方体,
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osteochondroma:骨软骨瘤
骨软骨瘤(osteochondroma)又称骨疣是最常见的良性肿瘤,可以单发或多发,也可与血管瘤同时存在,称Maffucci综合征. 孤立性骨软骨瘤多见于年龄较大的儿童;多发性骨软骨瘤或骨软骨瘤病,又称家族性子骺端续连症是一种遗传性疾病,属隐性遗传.