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Blister beetle or mylabris, pungent in flavor and toxic in nature, has been used for more than 2000 years as traditional Chinese medicine in China.
斑蝥为芫青科昆虫,南方大斑蝥或黄黑小斑蝥的干燥虫体,味辛、热,有大毒,在我国已经应用两千多年。
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Cantharidin, an active ingredient of the blister beetle, is an effective therapeutic agent against cancers of the liver, breast, esophagus, lung and intestine, etc.
斑蝥的有效成分为斑蝥素,对肝癌、乳腺癌、食道癌、肺癌、贲门癌和肠癌治疗有效,但毒性较大。
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Methodological furan and reaction of Diels-Alder of course of Ma Lai anhydride are generated go armour goes element of hydrogenous Chinese blister beetle, reductive below palladium charcoal catalysis into go element of armour Chinese blister beetle, with replace aniline condensation to become nitrogen - phenyl goes acyl of armour Chinese blister beetle inferior the ramification of amine.
方法呋喃和马来酐经过Diels-Alder反应生成去甲去氢斑蝥素,在钯炭催化下还原成去甲斑蝥素,和取代苯胺缩合成氮-苯基去甲斑蝥酰亚胺的衍生物。
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Norcantharidin can be made by artificial synthesis; it still be more suitable application than cantharidin in clinical use.
为了减少其副作用,斑蝥素的衍生物,斑蝥酸钠、去甲基斑蝥素等相继被研发出来;研究发现去甲基斑蝥素抗癌效果比斑蝥素强而无泌尿道刺激之副作用,尤其去甲基斑蝥素易人工合成,故而更适合作为临床应用。
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Mylabris has good anti-tumor effect, the effective ingredient of which is cantharidi. Norcanthaddin is prepared by artificial synthesis on the base of cantharidin, reducing the side-effect of cantharidin as well as keeping the antitumor activity of it.
斑蝥具有良好的抗肿瘤作用,其抗癌的有效成分是斑蝥素,但斑蝥素的副作用较大,去甲斑蝥素是在斑蝥素基础上人工合成的化合物,降低了斑蝥素的副作用而保留了抗癌活性。
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Methods The total cantharidin obtained with acidolysis method and the free cantharidin obtained with direct extraction method were determined in eight species of Meloidae and the control species Huechys sanguinea (Homoptera: Cicadidae) by gas chromatography, and the content of the bound cantharidin in each species was calculated with the content difference between the total cantharidin and the free cantharidin. The relationship between the contents of the bound cantharidin and the contents of Ca and Mg elements in Meloidae were assessed.
利用气相色谱法测定了8种芫菁和作为对照的黑翅红蝉体内总斑蝥素和游离斑蝥素的含量,总斑蝥素含量是通过酸水解法测得的,游离斑蝥素含量是通过直接浸提法测得的,以总斑蝥素与游离斑蝥素含量之差作为结合斑蝥素含量;并比较了结合斑蝥素与钙、镁含量之间的相关性。
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The aims of the writers study is to observe the effects of its inducing apoptosis and influencing cell cycle by treating esophageal carcinoma cases with sodium cantharidate before operation.
本研究通过术前应用斑蝥酸钠注射液,旨在观察其诱导食管癌肿瘤细胞凋亡、对肿瘤细胞周期的影响,并初步探讨两者的关系;通过测定p53、bcl-2基因表达在应用斑蝥酸钠后的变化,初步探讨斑蝥酸钠治疗食管癌的分子机制;同时测定应用斑蝥酸钠后的免疫功能变化,以期对斑蝥酸钠对机体的影响做出较全面的评价。
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The contents of the total cantharidin were higher than the contents of the free cantharidin in Meloidae. The bound cantharidin may exist in the forms of magnesium cantharidate and calcium cantharidate.
芫菁体内总斑蝥素含量远高于游离斑蝥素的含量;结合斑蝥素可能是以斑蝥素酸钙和斑蝥素酸镁形式存在。
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Results The results showed that the total cantharidin contents in the samples of Meloidae were 1 to 9 times the free cantharidin contents. The total cantharidin contents were generally higher than 2.0% of dry body weight and the free cantharidin contents were all less than 1.7% of dry body weight in Mcloidac.
芫菁体内总斑蝥素的含量为游离斑蝥素含量的1-9倍,总斑蝥素的含量一般多于虫体干重的2.0%,而游离斑蝥素的含量均低于虫体干重的1.7%。
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The synergists ZB-1 and ZB-6 have both positive synergism to the efficiencies of cantaridin and demethylcantharidin.
助剂ZB-1和ZB-6对斑蝥素和去甲斑蝥素均有增效作用,当助剂最佳加入量为8%时,同浓度ZB-1对斑蝥素和去甲斑蝥素胃毒致死中浓度的增效倍数分别为3.47和3.28倍;同浓度ZB-6对斑蝥素和去甲斑蝥素增效倍数分别为3.52和1.97倍。
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cantharidin:斑蝥素
目的比较血清肌酸激酶同工酶(CK-MB)质量和活性在缺血性心脏疾病中的差异和应用.方法采用免疫化学发光法和免疫抑制法同步检测血清中CK-MB的质量和活性.结果在48例缺血性心脏疾病患者中发生急性心肌梗死(AMI)12例,其CK-MB质量的诊......斑蝥素(cantharidin)是由芫菁科Meloidae等昆虫产生的单萜类防御物质,
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cantharis:斑蝥 (名)
cantharides 干斑蝥粉, 干斑蝥 (名) | cantharis 斑蝥 (名) | canthus 眼睛的两端; 眦; 眼角 (名)
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carotenoid:胡萝卜素
诸如阿朴胡萝卜素(apocarotene)虾青素(astaxanthin)及斑蝥黄质(canthaxanth济南山鹏经贸有限公司供应;加丽素红(carophyll red)即天然红色素,天然色素是属于一种天然的生理性色素,这种天然色素包括胡萝卜素(carotene)以及之为"类胡萝卜素"(carotenoid)者,诸如阿朴胡萝卜
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mitten crab:中华绒蝥蟹
阳澄湖大闸蟹己在欧洲泛滥成灾 科学家一直以来一直相信,两种外来的好斗甲壳类动物--北美淡水蟹(signal crayfish)和中华绒蝥蟹(Mitten Crab)(也就是我们常说的阳澄湖大闸蟹),即将展开史诗般的大决战,争夺英国的水下统治权,
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mitten crab:大闸蟹
科学家认为英国范围内的两个外来天性好斗的甲壳类动物--北美淡水蟹(signal crayfish) 和中国大闸蟹(Mitten Crab)--学名中华绒蝥蟹,
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spanish fly:斑蝥
洋斑蝥(Spanish fly)俗称西班牙苍蝇丸,是西方使用已有千年历史的老牌催情药. 西班牙苍蝇不同于普通的苍蝇,严格地讲,它们并非产自西班牙,而是一种土生土长的欧洲水泡甲虫. 该甲虫体内含有一种腐蚀性的酸性物质,叫做斑蝥素(Cantharidin).
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cantharides:斑蝥
民间传闻很多"春药"方子,包括洋葱、大蒜、葡萄酒等,但是比较有"口碑"的是浑名"西班牙苍蝇"的斑蝥(cantharides)和产于中非洲的育亨宾(yohimbine)树皮;不幸的是,据说他们产生壮阳催情效果时,通常已是中毒剂量(Mayo Clin Pro 1992; 67(5):477)!
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Meloidae:芫菁科
鞘翅目(Coleoptera)芫菁科(Meloidae)甲虫,约2,500种,会分泌出一种刺激性物质,称「斑蝥素」(cantharidin),主要是从斑蝥属(Mylabris)和欧洲的西班牙芫菁(Lytta vesicatoria, 俗称西班牙苍蝇)收集而来.