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Methods: Mononuclear cells were obtained from human peripheral blood by the method of Ficoll-Hypaque density gradient centrifugation.
目的：观察白藜芦醇对人外周血单核/巨噬细胞CC型趋化因子受体5(CCR5)表达的调节作用。
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Results: Resveratrol significantly ihibited growth and proliferation of SW480 cells in time and dose dependent manner.Resveratrol perturbed cell cycle,and arrested SW480 cells in S-phase accompanied with reducing G2-phase cells.The ultrastructural change of the SW480 cells treated with resveratrol were as following:the number of microvilli on the surface ofplasm membrance decreased and the nucleolar margination was frequent in nucleus.
结果：白藜芦醇能抑制SW480细胞的生长增殖，并呈时间浓度依赖性；白藜芦醇能影响SW480细胞的细胞周期分布，使细胞周期阻滞于S期，G1期细胞减少；经白藜芦醇处理的SW480细胞可出现细胞超微结构的改变：可见染色体边聚，细胞表面突起减少，胞质内空泡化等凋亡形态的变化。
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As noted above,membrane-stabilizers unexpectedly improved the heart function andprevented ER stress both in vivo and in cultured cells.We know that the membranestability depends on the sodium homeostasis in fact.To investigate whether ER stress isassociated with sodium channel action,which determins the membrane stability,wepretreated H9c2(2-1) cells with veratridine,a sodium channel activator.
上面的研究发现膜稳定剂在体内体外均抑制了内质网应激，并改善了心脏功能，而膜稳定作用实际上是维持细胞钠离子稳态的结果，为了研究内质网应激反应与钠离子活动的关系，我们用一种钠通道激活剂藜芦定刺激H9c2(2-1)细胞，30分钟时GRP78表达增加；24小时时PERK磷酸化和CHOP蛋白表达显著增加，说明钠离子通道过度激活诱发了内质网应激反应。
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Veratrum aldehyde synthesis of many drugs intermediates, methyl aldehyde method for raw materials in Champlain, after dimethyl sulfate methylation available to 20% sodium hydroxide as the solvent, 10-11 in the PH value of the under the conditions of synthesis; microwave irradiation is the use of microwave radiation heating to replace the traditional approach to synthesis of a product of methylation reactions, this method does not require solvents, and less by-products, but still need to use 15% sodium hydroxide to adjust pH.
藜芦醛是许多药物合成的中间体，甲基化法以香兰醛为原料，经过硫酸二甲酯甲基化可得，以20%氢氧化钠为溶剂，在PH值为10-11的条件下合成；微波辐射法是利用微波辐射代替传统加热方式进行甲基化反应合成产物，这种方法不需要溶剂，并且副产物少，但仍需要用15%氢氧化钠来调节酸碱度。
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The results of the rule of law with ordinary methylation by formaldehyde Veratryl three groups the average weight of 2.5609g, the average yield was 91.31%, the melting point of the three groups were 42.4 ~ 44.8 ℃, 41.5 ~ 45.2 ℃, 41.7 ~ 44.3 ℃, from the results of we can see that the three groups of the melt from the melting point greater than that which the product of the by-product of the detection of the melting point have a certain impact; and the legal system with microwave radiation by an average of Veratrum aldehyde quality 1.4016g, the average yield was 93.23 %, melting point of the three groups were 41.8 ~ 43.2 ℃, 41.3 ~ 42.6 ℃, 41.6 ~ 43.5 ℃, melting away from the three groups as compared with ordinary methods of measuring the melt-out from the small.
结果 用普通甲基化法制出来的三组藜芦醛平均质量为2.5609g，平均产率为91.31％，三组的熔点分别为42.4～44.8℃，41.5～45.2℃，41.7～44.3℃，从结果可以看出，三组熔点的熔距都比较大，证明产物当中的副产物对熔点的检测有一定的影响；而用微波辐射法制出来的藜芦醛平均质量为1.4016g，平均产率为93.23％，三组熔点分别为41.8～43.2℃，41.3～42.6℃，41.6～43.5℃，三组熔距较普通方法测出来的熔距小。
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Objective: To investigate the effect of resveratrol on Chemotactic Factors of Monocyte,the Plaque Stabilization of atheromatosis and the effect of antioxidation and the relationship with CD40 Pathway. And to probe the molecular mechanism for resveratrol of action on anti-atherosclerosis .
目的：研究白藜芦醇对单核细胞趋化相关分子的影响、抗氧化、稳定粥样斑块的作用及其与CD40途径的关系，探讨白藜芦醇抗动脉粥样硬化分子作用机制。
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Methods The method of methylation and microwave synthesis method of microwave radiation Veratryl aldehydes, synthesis of these two methods compare the yield of the product and the fundamental nature, analyzing the advantages and disadvantages of both methods.
采用甲基化的方法和微波微波辐射的方法合成藜芦醛，比较这两种方法合成产物的产率及基本性质，分析两种方法的优劣。
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Dimethyl carbonate was used as the methylating reagent, o-vanillin as the material and K2CO3 as the catalyzer to synthesize oV. The effect of material ratio, reaction time, reaction temperature and catalyzer dosage on its synthesis reaction was investigated.
方法］采用碳酸二甲酯作为甲基化试剂，以邻位香兰素为原料，无水碳酸钾为催化剂，合成邻藜芦醛，研究物料配比、反应时间、反应温度和催化剂量对反应的影响。
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Through the pig serum-induced rat model of liver fibrosis was observed in rat liver tissue morphology Resveratrol Liver tissue of the impact of HA,LN,C-Ⅳ,PⅢNP and the impact of HyP.
通过对猪血清诱导的肝纤维化大鼠模型，观察白藜芦醇大鼠肝组织形态学的影响及肝组织HA、LN、C-Ⅳ、PⅢNP及HyP的影响。
- 更多网络解释与藜芦化相关的网络解释 [注：此内容来源于网络，仅供参考]
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veratric：[化]藜芦酸的
hardening furnace 硬化炉 淬火炉 | veratric [化]藜芦酸的 | reference video synchronization 基准视频同步