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All groups were treated by infusing into stomach while the rat began to be induced the model. The normal group and hepatic fibrosis model group were treated with distilled water 10ml/kg everyday ;The colchicines treatment group were treated with 0.2mg/kg everyday ;the small middle and large dose of extract of Achillea millefolium L .treatment group were treated with extract of Achillea millefolium L .3ml/kg,6ml/kg,12ml/kg respectively everyday.
造模同时灌胃给药,空白对照组及肝纤维化模型组每日给予蒸馏水10ml/;阳性对照组每日给予秋水仙碱0.2 mg/;预防研究低、中、高剂量组分别给予蓍草提取物相当于生药3g/,6g/,12g/灌胃,1次/日。
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alcaptonuria; alkaptonuria:黑尿症;夺碱质尿症
夺碱质 alcapton;alkapton | 黑尿症;夺碱质尿症 alcaptonuria;alkaptonuria | 日本蓍草;羽衣草(日本)(蔷薇科) Alchemilla vulgaris L.;A.japonica Nakai et Hara;lady's mantle