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Methods The total proteins of untreated and INH-treated mc^2 155 cells were separated by ampholyte pH gradient-based two-dimensional gel electrophoresis (2-DE). Tire differential expression proteins were analyzed by using image analysis software. Results Proteins of control group arid INH-treated group contained 159 and 221 protein spots, respectively.
观察不同浓度的异烟肼处理前后耻垢分枝杆菌生长曲线,确定药物处理SM细胞的最佳时间和浓度,并提取在最佳处理时间和浓度条件下的SM细胞总蛋白,采用载体两性电解质pH梯度双向凝胶电泳技术分离异烟肼处理前后耻垢分枝杆菌mc^2 155细胞的总蛋白质,用PDuest 7.3.1图像分析软件比较分析,以识别差异表达的蛋白质。
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A549 cells are more sensitive to CDDP-induced apoptosis(P.01) and less sensitive to THP andβ-Ele-induced apoptosis than A375p(P.01, P.05 respectively). Condensation and crack of nucleus and apoptotic bodies appeared in apoptotic cells of A549 and A375p cell lines in all treated groups and necrocytosis were to be seen in some groups. Fluorescence imaging experiments demonstrated that accumulation of iASPP in cytoplasm but little distribution in nucleus in all groups. untreated groups in two cell lines presented a bright-green colour,followed by CDDP-treated groups,and THP-treated groups is the darkest one in all groups.
免疫荧光显示,未加药物处理的A549和A375p细胞胞质染色均匀呈亮绿色,核区较暗;CDDP及β-Ele处理组细胞为暗绿色,其中可见皱缩的凋亡细胞;THP处理的细胞胞质荧光弱呈灰绿色,由于THP嵌入DNA自发红色荧光与二抗的绿色荧光中和,胞核被染成桔红色,结果提示药物处理后A549和A375p细胞中iASPP的表达有不同程度的下降。
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Methods Microsatellite instable-high colon cancer cell line HCT116, microsatellite stable colon cancer cell line HT29, as well as control MSS breast cancer cell lines were treated by NMD inhibition drug emetine and actinomycin D.
方法采用NMD抑制药物emetine联合actinomycinD,分别处理高度微卫星不稳定型大肠癌细胞株HCT116和微卫星稳定的大肠癌细胞株HT29,以及对照的MSS乳腺癌细胞株,以全基因组cDNA芯片检测经药物处理和不经药物处理的细胞株的mRNA表达变化。
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Based on the security,efficacy,cheapness and easy gain three disinfectant drugs(acids, degerming agents,surface active agents)were chosen to killing coccidial oocysts in chicken.
本试验按照安全、有效、经济、来源容易的原则,从对鸡球虫卵囊有一定抑杀作用的三类消毒药物(酸类、消毒剂类、表面活性剂类)中,筛选了 17组不同药物和浓度的搭配组合,设计了 3个试验:抑制鸡球虫新鲜卵囊孢子化试验;抑杀孢子化卵囊试验;新鲜卵囊和孢子化卵囊经药物处理后感染小鸡试验。
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The data shoewed that esculetin, resveratrol enhanced LPL expression up to about 1.2 ~3.5 fold compared with the control group. In addition to fibrates, however, no effect on LPL expression by curcumin was observed. We concluded that esculetin and resveratrol enhanced LPL expression on CHO-K1 cell. We hope that we can apply these drugs to mutant form LPL, furthermore apply theses drugs into clinical treatment.
利用药物处理有转染带有完整人类脂蛋白解脂酶启动子和脂蛋白解脂酶cDNA 序列(-1715 ~+1643)质体的CHO-K1细胞,从细胞培养液以及细胞溶解物中发现,除了curcumin之外所有药物都可以使得细胞培养液以及细胞溶解液内的脂蛋白解脂酶活性有1.2至3.5倍的上升,由此结果可知除了curcumin外,esculetin和白藜芦醇以及其他fibrate药物可降低三酸甘油脂血症。
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Among the 45 neurons generating phasic firing, 8 (17.78﹪) neurons could still be induced phasic firing after treatment with 1×10-2 μg/mL SVHRP and 37 (82.22﹪) neurons had no responses to the stimulation. The AP firing of neurons was dramatically different after treatment with SVHRP (P<0.01, n=45). Among the 7 repetitive firing neurons, all of them could only generate 1 or 0 AP instead of repetitive firing when SVHRP was applied. The number of APs was 14.57±1.00 and 0.57±0.20 before and after SVHRP treatment (P<0.01, n=7). The AP rheobase was (75.10±8.99) pA and (119.85± 12.73) pA before and after 1 × 10-4 μg/mL SVHRP application, respectively (P<0.01,n=8). The AP threshold was increased from (-41.17±2.15) mV to (-32.40±1.48) mV after 1×10-4 μg/mL SVHRP treatment (P<0.01,n=8). The peak amplitude of AP was (68.49±2.33) mV for the neurons before treatment with 1×10-4 μg/mL SVHRP and (54.71±0.81)mV after treatment (P<0.01, n=8). These results showed that SVHRP could decrease the AP firing frequency, increase the AP rheobase and threshold, but decrease the AP peak amplitude of hippocampal neurons.
在产生位相放电的45个细胞中,有8个细胞在SVHRP处理后仍可以诱发出位相放电(占17.78﹪);37个细胞在SVHRP处理后无法诱导出位相放电(占82.22﹪),SVHRP处理后动作电位的产生与处理前相比,有显著差异(P<0.01,n=45);在产生重复放电的7个细胞中,在1×10-2μg/mL SVHRP作用后均不能再次诱发出重复放电,而是产生一个动作电位或不再产生动作电位,药物处理前产生的动作电位个数为14.57±1.00,SVHRP处理后产生动作电位的个数为0.57±0.20,二者之间有显著性差异(P<0.01,n=7)。1×10-4 μg/mLSVHRP处理后,诱发动作电位产生的基强度由(75.10±8.99)pA增加到(119.85±12.73)pA(P<0.01,n=8);阈电位由(-41.17±2.15)mV升至(-32.40±1.48)mV(P<0.01,n=8);动作电位峰值由(68.49±2.33)mV下降至(54.71±0.81)mV(P<0.01,n=8)。
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Methods The net treated by BASF pesticide, the net treated by BASF pesticide after washing twenty times and the net treated by Fendona TM recommended by WHO were used in treated area, and common military nets were selected in the control areas. Aedes vexans, the dominant species in Beiwan, was collected by mosquito aspirators and released into nets. The first knockdown time, medium knockdown time and total knockdown time were recorded, and then compare the knockdown time of 4 kinds of mosquito-net.
研究中选用经BASF药物处理蚊帐、20次洗涤的BASF药物处理蚊帐、5 ml有效成分10%的奋斗呐处理的普通蚊帐,普通军用蚊帐作为对照,在野外环境中用吸蚊器采集当地优势蚊种刺扰伊蚊分别放入4种处理蚊帐中,观察4种处理蚊帐对当地蚊虫的首数击倒、半数击倒、全数击倒时间,最后比较分析4种处理蚊帐对当地主要蚊种的快速击倒效果。
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After forming the tooth week bag, usually carried on a medicine processing to the tooth week bag, can place to go into various medicine in the tooth week bag, such as iodine glycerin, compound prescribe iodine liquid or anti-virus medicine, make the tooth kept a higher medicine density inside the bag for week, exterminate a tooth various germ of bag attained to disinfect, eliminate inflammation and refrained from rash action for week of function.
形成了牙周袋后,通常对牙周袋进行药物处理,可在牙周袋内置入各种药物,如碘甘油、复方碘液或抗菌药物,使牙周袋内保持较高的药物浓度,消灭牙周袋的各种细菌,达到杀菌、消炎和收敛的作用。
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The relationship between MFs and MTs in the organization of PPB was investigated in garlic root tip cells subjected to treatment with cytochalasin D , latrunculin A and phalloidin .
用微丝特异性解聚药物(细胞松弛素CD和LAT A)以及微丝稳定药物处理大蒜根尖分生组织细胞的实验结果表明:微丝被破坏后,导致了早前期微管带宽度明显增加,Ph处理则对早前期微管带的宽度无影响。
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The levels of E2F1 proteins could return to normal at 2h and 16h in high MOI infected cells treated with large dosage of allitridin.⑤The effects of allitridin on regulating the transcription and expression of dhfr gene in HCMV infected cells: The higher transcription of dhfr gene of high MOI infected cells within 4-16h was partially or wholely antagonised by allitridin. The up-regulated dhfr mRNA levels of low MOI infected cells nearly returned to normal after allitridin treatment.
大蒜新素处理HCMV感染细胞对E2F蛋白表达的影响:大蒜新素处理低MOI和高MOI感染细胞可使病毒诱导上调的E2F蛋白表达水平下调,大剂量药物处理高MOI感染细胞2h和16h时E2F蛋白回复至正常细胞水平,其作用特点为:药物对高MOI感染细胞的拮抗作用优于对低MOI感染细胞的处理;大剂量药物作用优于中剂量药物;对病毒在感染早期(16h内)诱导效应的拮抗作用强于对病毒感染中期(24h)诱导效应的拮抗。
- 更多网络解释与药物处理相关的网络解释 [注:此内容来源于网络,仅供参考]
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dot:美国交通运输部
日本政府厚生劳动省 (MHLW) 食物及保健食品检 美国食品及药物管理局 (FDA) 药物出品注册认可 美国农业部 (USDA) 认可测试肉类及家禽制品内 美国交通运输部 (DOT) 处理危险物品登记品及药物管理局 (FDA) 所制定GMP (Good
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enantiomer:对映体
手性药物有的以消旋体(racemate)形式上市,有些以单一对映体(enantiomer)上市. 在临床应用中必然涉及到相互作用的问题. 由于没有认识到手性药物各对映体的药效学或药动学行为可能不同,所以以往相互作用的研究中常常将消旋体药物当作单一化合物来处理,
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medico:医师,医学生
medication 药物治疗,药物处理,医药 | medico 医师,医学生 | medicolegal 法医学的
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pharmacodynamics:药(物)效(应)动力学
药理学研究的主要对象是机体,属于广义的生命科学范畴,主要有三方面的研究内容:1.药物作用下机体细胞功能如何发生生理生化与分子生物学改变,称为"药物效应动力学"(Pharmacodynamics);2.药物本身在体内的过程,即机体如何对药物进行处理,
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homeopathic pharmacopoeia:顺势疗法药典
一个药物在美国药典(USP)和顺势疗法药典(Homeopathic Pharmacopoeia)中均有记载和承认,应该依照USP要求处理,但如量作为顺势疗法药物标签或出售者,则按照顺势疗法要求处理.
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racemate:消旋体
手性药物有的以消旋体(racemate)形式上市,有些以单一对映体(enantiomer)上市. 在临床应用中必然涉及到相互作用的问题. 由于没有认识到手性药物各对映体的药效学或药动学行为可能不同,所以以往相互作用的研究中常常将消旋体药物当作单一化合物来处理,
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SELF-MANAGEMENT PLAN:自我处理方法
- KNOWLEDGE OF THE DRUGS GIVEN 药物的认识 | - SELF-MANAGEMENT PLAN 自我处理方法 | - PREVENTION OF ATTACKS 避免哮喘病发作
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Pharmacologic preconditioning:药物预适应
缺氧预处理:hypoxic preconditioning | 药物预适应:pharmacologic preconditioning | 低氧预适应:Hypoxia preconditioning
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hypoxic preconditioning:缺氧预处理
缺血预适应:Preconditioning | 缺氧预处理:hypoxic preconditioning | 药物预适应:pharmacologic preconditioning
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wholesale dealer:批发商
"生鸦片"(raw opium)指任何种类未经处理以供吸食、吸服、服食或注射的鸦片,也指内有包裹生鸦片的叶或外皮,但不包括鸦片烟渣;"危险药物"(dangerous drug)指任何在附表1第I部中所指明的药物或物质;"批发商"(wholesale dealer)指经营出售危险药物,