- 更多网络例句与苯核相关的网络例句 [注:此内容来源于网络,仅供参考]
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And because the structure of benzene nucleus as rigid and flexible alternating permutation of the hydrocarbon chain in order to facilitate the physical properties of polyacrylamidewith pingment.
又因其布局为刚性的苯核和柔性的烃链瓜代摆列,催促涂膜的物理板滞本能机能增不弱。
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During the manufacturing of the critical intermediate cephalosporin nucleus --7-amino-3-chloro-cephalosporanic acid diphenylmethyl ester hydrochloride salt, first the feasibility of the one-pot synthetic route of open loop, closed loop and ozonization when chlorine is passed over is qualified by experiments. Then the critical factors that will influence this reaction are studied as follows: the mol ratio of triphenyl phosphite and Diphenylmethyl 3-hydroxy-7-phenylacetaminoceph-3-em-4-carboxylate-l-oxide is four to one; the quantity of the stablizer should be at least more than two to one. The temperature of the system must be 25℃ when chlorine is passed over so that the hydrochloride can be precipitated to obtain cephalosporin nucleus of cefaclor--7-amino-3-chloro-cephalosporanic acid diphenylmethyl ester hydrochloride salt.
在制备关键中间体头孢母核7-氨基-3-氯头孢烷酸二苯甲酯盐酸盐时,先通过实验验证把开环、闭环、臭氧化三步在通入氯气时并为一锅煮的合成路线的可行性之外,又研究了影响该反应的几个重要因素:亚磷酸三苯酯与3-羟基-7-头孢烷-5-亚砜-2-甲酸二苯甲酯的摩尔比为4:1;稳定剂2-甲基-2-丁烯的用量至少大于2:1,通入氯化氢气体时体系温度在25℃时盐酸盐则能够顺利析出,获得头孢克洛的头孢母核—7-氨基-3-氯头孢烷酸二苯甲酯盐酸盐。
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Some research and analysis on the reaction of 2,4-difluoronitrobenzene and nucleophilic reagent alcohol sodium (methyl alcohol ,ethyl alcohol, propyl alcohol, n-butyl alcohol, t-butyl alcohol, et hl) and the reaction choice of opposite -F in different solvent and conditions have done in this paper.
论文以2,4-二氟硝基苯为主要原料,研究了其与亲核试剂醇钠(甲醇、乙醇、丙醇、正丁醇、叔丁醇等)在不同溶剂中的反应情况,讨论了在几种代表性的溶剂——醇、四氢呋喃、苯、N,N-二甲基甲酰胺中亲核取代反应的情况,研究了温度、反应时间、亲核试剂、溶剂等条件对亲核取代反应的影响。
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The DSC results showed that calcium carbonate,sodium benzoate and terephthalic acid were the nucleating agents of polypropylene with high thermal stability of the nucleating effect,while the thermal stability of nucleating effect of pimelic acid,suberic acid,azelaic acid,and the two component nucleating agents suberic acid/calcium carbonate and azelaic acid/calcium carbonate were poor.
研究了碳酸钙、苯甲酸钠、对苯二甲酸和脂肪二元酸:庚二酸、辛二酸、壬二酸及其与碳酸钙组成的双组分成核剂对聚丙烯结晶成核效果的热稳定性。结果表明,高熔点物质碳酸钙、对苯二甲酸、苯甲酸钠的成核效果的热稳定性高,而脂肪二元酸的成核热稳定性低。庚二酸与碳酸钙组成的双组分成核剂的成核热稳定性高,但辛二酸、壬二酸与碳酸钙组成的双组分成核剂的成核热稳定性没有得到改善。
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To explore new synthetic methods, we set out a careful investigation of the reaction of benzimidazolium salt with many nucleophilic agents, including the active aromatic compounds and heteratom nucleophilic agents, and found that the quaternary C=N is not so active; when benzimidazolium salt is reacted with big nitrogen nucleophilic agent? phthalimide, it does not give the expected addition product, instead, produces N-alkyl phthalimide through alkyl-transfermation from benzimidazolium salt to phthalimide.
为了开发新的合成方法,研究了苯并咪唑盐与各种亲核试剂(活泼芳环与杂原子亲核试剂)的反应,发现苯并咪唑盐不与活泼芳环及杂原子亲核试剂发生2位加成反应;在与体积较大的位阻型N亲核试剂邻苯二甲酚亚胺反应时,未得到亲核试剂与极化的C=N的加成产物,而是得到N烷基化的邻苯二甲酰亚胺,进一步研究表明,苯并咪唑盐将1(3)位N上的烷基转移给了邻苯二甲酰亚胺,并讨论了其反应机理和取代基,溶剂效应。
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They were two new compounds, [cyclo(Pro-Val-Phe-Phe-Pro-Val-Phe-Ser-Leu),7],[2-N-(1-methoxycarbonylethyl)guanosine, 10], and eight known compounds,(p-hydroxybenzoic acid, 1),(methyl succinate, 2),(russulaceramide, 3),(phenylalanine, 4),(guanine, 5),(β-carboline, 6),(uridine, 8), and (adenosine, 9). All the compounds were isolated from Amanita exitialis for the first time.
分别为:对羟基苯甲酸(p-hydroxybenzoic acid,1)、丁二酸二甲酯(methyl succinate,2)、神经酰胺(russulaceramide,3)、苯丙氨酸(phenylalanine,4)、鸟嘌呤核苷(guanine,5)、β-咔啉(β-carboline,6)、环(脯氨酸-缬氨酸-苯丙氨酸-苯丙氨酸-脯氨酸-缬氨酸-苯丙氨酸-丝氨酸-亮氨酸) [cyclo(Pro-Val-Phe-Phe-Pro-Val-Phe-Ser-Leu),7]、尿嘧啶核苷(uridine,8)、腺嘌呤核苷(adenosine,9)、2-N-(1-甲氧羰基乙基)鸟苷[2-N-(1-Methoxycarbonylethyl)guanosine, 10]。10个化合物均为首次从致命鹅膏中分离得到,其中化合物7和10为新化合物。
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Results:(1) The rats produced amphetamine CPP after treated with 2 mgkg^(-1) amphetamine for 4 days. Ketamine and low, middle, high dose rhynchophylline all could eliminate the CPP effect, and the effect of rhychophylline was increased in a dose-dependent manner. Rhychophylline itself could not induce CPP in normal rats.(2) When compared with normal rats, the NR2B expression in nucleus accubens and amygdaloid of the model rats was obviously increased. Ketamine and middle, high dose rhynchophylline could decrease NR2B expression induced by amphetamine, while low dose rhynchophylline did not affect NR2B expression. Rhynchophylline had no effect on RN2B expression in normal rats.
结果:(1)建立了苯丙胺(2mgkg^(-1),连续4d)诱导的位置偏爱模型,氯胺酮及钩藤碱低、中、高剂量均可消除苯丙胺诱导的位置偏爱效应,随钩藤碱剂量增加其效应加强,且本身无精神依赖性;(2)苯丙胺模型组大鼠伏核和杏仁核NR2B蛋白表达增加,氯胺酮及钩藤碱中、高剂量抑制NR2B表达,低剂量及本身对NR2B表达无影响。
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There are three different nucleophilic reagent respectively reaction with m-dinitrobenzene ramification at distint alkaline term:With the nitrobenzene 、 m-nirtobenzenesulfone sodium salt 、 2.4-dinitro chlorobenzene 、 m-dinitrobenzene for bottom thing, benzyl cyanide、 benzyl chloride、 benzyl chloropyridine、is a nucleophilic reagent reaction for under the different term proceeds a series reaction. At the same time ,discuss about the impact factor to nucleophilicity such as the number of attract electron group、 ability of attract electron and the nucleophilic substitution reaction part.
设计了三类不同的亲核试剂分别与活化芳环在不同的碱性条件下发生反应:以苄基氰、苄基氯化吡啶为亲核试剂,以硝基苯、间二硝基苯、间硝基苯磺酸钠、2,4-二硝基苄基氯为底物进行亲核取代反应;并且对亲核试剂的体积效应、溶剂效应对亲核性影响,底物上吸电子基团的数目、吸电子能力对亲电性的影响,以及亲核取代反应的发生部位受哪些因素影响进行探讨。
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The effects and mechanism of GABAergic neurons, NOergic neurons, opioid peptide and cyclic adenosine monophosphate in the nucleus reticularis thalami on sleep-wakefulness cycle of rats and the effects and mechanism of the 5-HTergic nerve fibers project from the nucleus raphes dorsalis to RT on sleep-wakefulness cycle of rats were investigated with the methods of brain stereotaxic, nucleus spile, microinjection and polysomngraphy.1. The effects of GABAergic neurons in RT on sleep-wakefulness cycle of rats1.1 Microinjection of 3-mercaptopropionic acid (3-MP, a kind of glutamate decarboxylase inhibitor) into RT. On the day of microinjection, sleep only decreased a litter. On the second day, sleep marked decreased and wakefulness marked increased. On the third and fourth day, sleep and wakefulness stages resumed to normal.1.2 Microinjection of gamma-amino butyric acid (GABA 1.0μg) into RT enhanced sleep and reduced wakefulness compared with control; while microinjection of L-glutamate (L-Glu, 0.2μg) decreased sleep and increased wakefulness; microinjection of bicuculline (BIC, 1.0μg), a GABAA receptor antagonist, enhanced wakefulness and reduced sleep; microinjection of baclofen (BAC, 1.0μg), GABAB receptor agonist, had the same effects as GABA.2. The effects of NOergic neurons in RT on sleep-wakefulness cycle of rats2.1 Microinjection of L-arginine (L-Arg, 0.5μg) into RT decreased sleep compared with control, but there were on statistaical difference between L-Arg group and control; while microinjection of sodium nitroprusside (SNP, 0.2μg), a NO donor into RT, sleep marked decreased and wakefulness marked increased. Microinjection of nitric oxide synthase inhibitor, N-nitro-L-arginine (L-NNA, 2.0μg) into RT enhanced sleep and reduced wakefulness.2.2 After simultaneous microinjection of L-NNA (2.0μg) and SNP (0.2μg) into RT, SNP abolished the sleep-promoting effect of L-NNA compared with L-NNA group; after simultaneous microinjection of L-NNA (2.0μg) and L-Arg(0.5μg) into RT, we found that L-NNA could not blocked the wakefulness-promoting effect of L-Arg.3. The effects of opioid peptide in RT on sleep-wakefulness cycle of rats3.1 Microinjection of morphine sulfate (MOR, 1.0μg) into RT increased wakefulness and decreased sleep compared with control; while microinjection of naloxone hydrochloride (NAL, 1.0μg), the antagonist of opiate receptors, into RT, enhanced sleep and reduced wakefulness.3.2 After simultaneous microinjection of MOR (1.0μg) and NAL (1.0μg) into RT, the wakefulness-promoting effect of MOR and the sleep-promoting effect of NAL were not observed compared with control.4. The effects of cAMP in RT on sleep-wakefulness cycle of rats Microinjection of cAMP (1.0μg) into RT increased sleep and decreased wakefulness compared with control; microinjection of methylene blue (MB,1.0μg) into RT enhanced sleep and reduced wakefulness compared with control.5. The effects of the 5-HTergic nerve fibers project from DRN to RT on sleep-wakefulness cycle of rats5.1 When L-Glu (0.2μg) was microinjected into DRN and normal sodium (NS,1.0μg) was microinjected into bilateral RT. We found that sleep was decreased and wakefulness was increased compared with control; when L-Glu (0.2μg) was microinjected into DRN and methysergide (MS,1.0μg), a non-selective 5-HT antagonist, was microinjected into bilateral RT, We found that sleep was enhanced and wakefulness was reduced compared with L-Glu group.5.2 When p-chlorophenylalanine (PCPA, 10μg) was microinjected into DRN and NS (1.0μg) was microinjected into bilateral RT, We found that sleep was increased and wakefulness was decreased compared with control; microinjection of 5-hydroxytryptaphan (5-HTP, 1.0μg), which can convert to 5-HT by the enzyme tryptophane hydroxylase and enhance 5-HT into bilateral RT, could block the effect of microinjection of PCPA into DRN on sleep-wakefulness cycle.
本研究采用脑立体定位、核团插管、微量注射、多导睡眠描记等方法,研究丘脑网状核(nucleus reticularis thalami,RT)中γ-氨基丁酸(gamma-amino butyric acid ,GABA)能神经元、一氧化氮(nitrogen monoxidum,NO)能神经元、阿片肽类神经递质、环一磷酸腺苷(cyclic adenosine monophosphate,cAMP)及中缝背核(nucleus raphes dorsalis,DRN)至RT的5-羟色胺(5-hydroxytryptamine,5-HT)能神经纤维投射对大鼠睡眠-觉醒周期的影响及其作用机制。1 RT内GABA能神经元对大鼠睡眠-觉醒周期的影响1.1大鼠RT内微量注射GABA合成关键酶抑制剂3-巯基丙酸(3-MP,5μg),注射当天睡眠时间略有减少,第二日睡眠时间显著减少,觉醒时间明显增多,第三、四日睡眠和觉醒时间逐渐恢复至正常。1.2大鼠RT内微量注射GABA受体激动剂GABA( 1.0μg)后,与生理盐水组比较,睡眠时间增加,觉醒时间减少;而RT内微量注射L-谷氨酸(glutamic acid, L-Glu, 0.2μg)后,睡眠时间减少,觉醒时间增加;RT内微量注射GABAA受体阻断剂荷包牡丹碱(bicuculline,BIC,1.0μg)后,睡眠时间减少,觉醒时间增加;RT内微量注射GABAB受体激动剂氯苯氨丁酸(baclofen,BAC,1.0μg)后,产生了与GABA相似的促睡眠效果。2 RT内NO能神经元对大鼠睡眠-觉醒周期的影响2.1大鼠RT内微量注射NO的前体L-精氨酸(L-Arg,0.5μg)后,与生理盐水组对比,睡眠时间略有减少,但无显著性意义;而RT内微量注射NO的供体硝普钠(Sodium Nitroprusside,SNP,0.2μg)后可明显增加觉醒时间,缩短睡眠时间;微量注射一氧化氮合酶抑制剂L-硝基精氨酸(L-arginine,L-NNA,2.0μg)后,引起睡眠时间增多,觉醒时间减少。2.2大鼠RT内同时微量注射L-NNA(2.0μg)和SNP(0.2μg)后与L-NNA组比较发现SNP逆转了L-NNA的促睡眠作用;RT内同时微量注射L-NNA(2.0μg)和L-Arg(0.5μg)后,与L-NNA(2.0μg)组比较发现L-Arg可以增加觉醒而缩短睡眠,其促觉醒作用未能被NOS的抑制剂L-NNA所逆转。3 RT内阿片肽对大鼠睡眠-觉醒周期的影响3.1大鼠RT内微量注射硫酸吗啡(morphine sulfate,MOR,1.0μg)后与生理盐水组对比,睡眠时间减少而觉醒时间增加; RT内微量注射阿片肽受体拮抗剂盐酸纳洛酮(naloxone hydrochloride,NAL,1.0μg)后与生理盐水组比较,睡眠时间增加而觉醒时间减少。3.2大鼠RT内同时微量注射MOR(1.0μg)和NAL(1.0μg)后,与生理盐水组对比,原有的MOR促觉醒效果和NAL的促睡眠效果都没有表现。4 RT内环一磷酸腺苷信使对大鼠睡眠-觉醒周期的影响大鼠RT内微量注射cAMP(1.0μg)后与NS(1.0μg)组比较,睡眠时间增多而觉醒时间减少;RT内微量注射亚甲蓝(methylene blue,MB,1.0μg)后,与NS组比较,睡眠时间增多而觉醒时间减少。5中缝背核投射到丘脑网状核的5-羟色胺能神经纤维对大鼠睡眠-觉醒周期的影响5.1大鼠DRN内微量注射L-Glu(0.2μg),同时在双侧RT内微量注射NS (1.0μg)后,与对照组(DRN和双侧RT注射NS, 0.2μg)比较,睡眠时间减少,觉醒时间增多;大鼠DRN内微量注射L-Glu(0.2μg),同时在双侧RT内微量注射二甲基麦角新碱(methysergide, MS, 1.0μg )后,与对照组(DRN注射L-Glu 0.2μg,双侧RT注射NS 1.0μg)比较,睡眠时间增多,觉醒时间减少。5.2大鼠DRN内微量注射对氯苯丙氨酸(p-chlorophenylalanine,PCPA,10μg),同时在双侧RT内微量注射NS (1.0μg)后,与对照组(DRN和双侧RT注射NS, 1.0μg)比较,睡眠时间增多,觉醒时间减少;大鼠DRN内微量注射PCPA(10μg),产生睡眠增多效应后,在双侧RT内微量注射5-羟色胺酸(5-hydroxytryptaphan , 5-HTP, 1.0μg )后,与对照组(DRN注射PCPA 10μg,双侧RT注射NS 1.0μg)比较,睡眠时间减少,觉醒时间增多。
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With the nitrobenzene、 m-chloronitrobenzene、 m-nirtobenzenesulfone sodium salt for bottom thing, Grinard agent is a nucleophilic reagent reaction for under the different term proceeds a series reaction.
以苄基氯化镁为亲核试剂,以硝基苯、间硝基氯苯、间硝基苯磺酸钠为底物进行亲核取代反应,探讨与芳环相连的吸电子基团的数目及吸电子性,对亲核取代反应的影响。
- 更多网络解释与苯核相关的网络解释 [注:此内容来源于网络,仅供参考]
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coumarin:香豆素
香豆素(Coumarin)是具有苯骈α-吡喃酮母核的一类天然化合物的总称,广泛存在于植物界中,以伞形科和芸香科植物中最为常见.其往往以游离状态或与糖结合成苷的形式存在于植物的花、茎、叶、果实等部位中.香豆素有多方面的生理活性:对植物有双重生理活性,
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Micronucleus Assay:(微核测定)
Microarray Analysis(微阵列分析) | Micronucleus Assay(微核测定) | Microtox(氨苯磺胺)
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phenanthrene nucleus:菲核
phenacyl halide 苯甲酰甲基卤 | phenanthrene nucleus 菲核 | phenanthrene ring 菲环
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polyethylene terephthalate:聚对苯二甲酸乙二醇酯
2009年9月,德国PolyIC GmbH & Co.KG公司通过这项技巧,将聚对苯二甲酸乙二醇酯(polyethylene terephthalate)作为基板,开发出一个20位的内存. 并行处理技巧已经以双核和四核个人电脑处理器以及用于嵌进利用的多核异质处理器的情势存在. 不过,
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ribose phenylhydrazone:核糖苯腙
核糖 ribose | 核糖苯腙 ribose phenylhydrazone | 核酮糖 ribulose
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triphenylmethane;rosaniline:三苯甲烷
三苯乙烯 triphenylethylene | 三苯甲烷 triphenylmethane;rosaniline | 核苷三磷酸吡啶;三磷酸吡啶核苷酸;辅酶 II triphosphopyridine uncleotide;TPN;Co.II;NADP
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phenacyl halide:苯甲酰甲基卤
phenacyl ester 苯乙酮酯 | phenacyl halide 苯甲酰甲基卤 | phenanthrene nucleus 菲核
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nucleating agent:成核剂
4.13.1 成核剂(Nucleating agent)有些无机粉未在发泡中可使泡棉结构更为细致. (a) 电子照射 ( Electron Bean Irradiation ) ﹔多氯联苯(PCB)类﹔多氯化奈类﹔有机锡化合物(三丁基锡类或三苯基锡类)﹔石棉﹔偶氮化合物﹔铅和铅化合物﹔汞和汞化合物﹔六价铬及其化合物等其它有害环境物质.
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benzene nucleus:苯核
benzene hydrocarbon 苯系烃 | benzene nucleus 苯核 | benzene ring 苯环
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eucaryotic cells:真核细胞
ethidium bromide 溴乙非啶,溴化二氨乙苯啡啶 | eucaryotic cells真核细胞 | Exergonic放能的