苯并咪唑

基本解释 (translations)

benzimidazole  ·  benziminazole

与苯并咪唑相关的网络例句 [注：此内容来源于网络，仅供参考]

But in the + moiety, the three benzimidazole rings shared the whole space equally, the dihedral angel among them is about 120°, just like three fan blades of an airscrew, the molecular structure appear gear-like shape.

X-射线单晶衍射测试、红外、紫外等方法确定了三(2-苯并咪唑亚甲基)胺的Fe和Co配合物的结构，由晶体结构发现金属配位情况不同、配合物在结构上存在着差异，Fe为八面体构型，而Co为三角双锥构型；其次，两配合物中的苯并咪唑环间夹角不同，配合物中包含N2和N4的两个苯并咪唑环间夹角仅为9.41(0.11)，几乎构成一个平面，呈蝴蝶形；后者Co三个苯并咪唑环几乎平分了整个空间，它们之间的夹角约为120，呈三扇叶螺旋桨式构型，为齿轮形。

Ophenyl phenol,ophenyl phenol sodium salt tetrahydrate,7ADCA,2ethyl phenyl hydrazine hydrochloride,2,3dihydrofuran,7ethyl3(2hydroxy ethyl)indole,methyl ester of etodolac; 1,8diethyl1,3,4,9tetrahydropyrano[3.4b] indole1acetic acid methyl ester,5chloro2methoxy benzoic acid,4(2aminoethyl)benzene sulfonamide,5cyano phthalide,phthalhydrazide,9thioxanthenone,n[(1,4benzodioxane2yl)carboxyl]piperazine HCL,2chloro4amino6,7dimethoxyquinazoline,2chloro benzimidazole,1(4fluorobenzyl)2chlorobenzimidazole,2methylthio4pyrimidone,5amino4imidazole carboxamide HCL,6chloro2hexanone,11oxo6.11hydrodibenzothiepin,6,11dihydrodibenzooxepin11one,10,11dihydrodibenzocyclohepten5one;dibenzosuberone,dibenzo cyclohepten5one;dibenzosuberenone,3,5dihydroxy benzoic acid,3,5dihydroxy benzyl alcohol,2mercapto benzimidazole,3,4dihydroxy benzaldehyde,3,4dihydroxy benzonitrile,2amino5chloro benzonitrile,2(4chlorophenoxy)ethyl chloride,2(4chloro phenoxy)tert,butane,ditrimethylol propane;DTMP,2,2bis(4hydroxyphenyl)butane; bisphenol B,1,1'bis(4hydroxyphenyl)cyclohexane;bisphenol Z,tetrabromobisphenolS,3,5ditertbutyl salicylic acid,3,4,5trihydroxy benzoic acid stearyl ester,1,2,4trimethoxybenzene.

华业公司产品：邻苯基苯酚，邻苯基苯酚钠盐，7氨基3去乙酰氧基头孢烷酸，邻乙基苯肼盐酸盐，2，3二氢呋喃，7乙基色氨醇，依托度酸甲酯，5氯2甲氧基苯甲酸，4(2氨乙基)苯磺酰胺，5氰基苯酞，双酮酞嗪，9噻吨酮，N〔(1，4苯并二恶烷2基)羰基〕哌嗪盐酸盐，2氯4氨基6，7一二甲氧基喹唑啉，2氯苯并咪唑，1(4氟苄基)2氯苯并咪唑，2甲硫基4嘧啶酮，5氨基咪唑4 甲酰胺盐酸盐，6氯2已酮，11氧6.11二氢苯并〔b.c〕虑平，11氧代6，11二氢二苯并氧杂卓，10，11二氢二苯并环庚烯5酮，二苯并环庚烯5酮，3，5二羟基苯甲酸，3，5二羟基苯甲醇，2巯基苯并咪唑，3，4二羟基苯甲醛，3，4二羟基苯腈，2氨基5氯苯腈，2(4氯苯氧基)1氯乙烷，2(4氯苯氧基)叔丁烷，双丙烷，2，2二(4羟基苯基)丁烷；双酚B，1，1'双(4羟基苯基)环己烷；双酚Z，2[3，5二溴4(2，3二溴丙氧基)]苯砜，3，5二叔丁基水杨酸，3，4，5三羟基苯甲酸十八烷基脂，1，2，4三甲基氧基苯。

The initial SAR studies indicated:(1) the presence of a linker of methene at the N-1 may be beneficial to anti-HIV activity, while longer chain could enhance toxicity;(2) substituted phenyl at the C-2 could reduce toxicity;(3) 6-substituted benzimidazoles generally showed higher anti-HIV activity than 5-substuted ones;(4) the presence of a halogenated benzyl ring at the N-l would enhance anti-HIV potency and decrease cytotoxicity.

初步构效分析提示：(1)苯并咪唑环1位侧链间隔基为亚甲基时活性最好，侧链延长，毒性增大；(2)苯并咪唑2位侧链无间隔基毒性相对较低；(3)苯并咪唑6位取代活性高于5位取代；(4)苯并咪唑1位芳环用卤素取代，毒性明显降低。

The initial SAR studies indica ted:(1)the presence of alinker of methene at the N-1may be beneficial to anti-HIV activity,while longer chain could enhance toxicity;(2)substituted phenyl at the C-2could reduce toxicity;(3)6-substituted benzimidazoles generally showed higher anti-HIV activity than 5-substuted ones;(4)the presence of ahalogenated benzyl ring at the N-l would enhance anti-HIV potency and decrease cytotoxicity.

初步构效分析提示：(1)苯并咪唑环1位侧链间隔基为亚甲基时活性最好，侧链延长，毒性增大；(2)苯并咪唑2位侧链无间隔基毒性相对较低；(3)苯并咪唑6位取代活性高于5位取代；(4)苯并咪唑1位芳环用卤素取代，毒性明显降低。

Three kinds of small molecular copper and zinc superoxide dismutase mimics were synthesized with N, N-bis (benzimidazol-2-ylmethyl) amine (N3), N, N-bis (benzimidazol-2-ylmethyl) methylamine(MN3) and N,N-bis (benzimidazol-2-ylmethyl) benzylamine(BN3) as ligands. The com-plexes were characterized by UV, IR and element analysis and the structures were proposed.

模拟铜一锌超氧化物歧化酶的活性中心，以二(2-苯并咪唑)丙烷为桥、二(2-苯并咪唑亚甲基)胺(N3)、二(2-苯并咪唑亚甲基)甲胺(MN3)及二(2-苯并咪唑亚甲基)苄胺(BN3)为配体合成了3种异双核的小分子模型化合物，并进行了紫外、红外表征及元素分析，推测了可能的结构。

An unreported compound 2-cyclopropylbenzimidazolium salt was obtained from 2-cyclopropyl benzimidazole and iodomethane.

以邻苯二胺和环丙基甲酸为原料，以多聚磷酸为催化剂，在微波辐射下合成了环丙基苯并咪唑，用碘甲烷季胺化得到未见文献报道的环丙基苯并咪唑盐，通过苯并咪唑盐与Grignard试剂加成后水解反应制备环丙基甲基酮。

To explore new synthetic methods, we set out a careful investigation of the reaction of benzimidazolium salt with many nucleophilic agents, including the active aromatic compounds and heteratom nucleophilic agents, and found that the quaternary C=N is not so active; when benzimidazolium salt is reacted with big nitrogen nucleophilic agent? phthalimide, it does not give the expected addition product, instead, produces N-alkyl phthalimide through alkyl-transfermation from benzimidazolium salt to phthalimide.

为了开发新的合成方法，研究了苯并咪唑盐与各种亲核试剂（活泼芳环与杂原子亲核试剂）的反应，发现苯并咪唑盐不与活泼芳环及杂原子亲核试剂发生2位加成反应；在与体积较大的位阻型N亲核试剂邻苯二甲酚亚胺反应时，未得到亲核试剂与极化的C＝N的加成产物，而是得到N烷基化的邻苯二甲酰亚胺，进一步研究表明，苯并咪唑盐将1（3）位N上的烷基转移给了邻苯二甲酰亚胺，并讨论了其反应机理和取代基，溶剂效应。

A convenient method to synthesize three kinds of novel 2-(2-hydroxyphenyl) benzimidazole in order to improve the solubilities of the fluorophores with substituent of carboxyl, ester and double-bond which are aimed for determining the sulphydryl group was reported.

合成了N-{3-(2-苯并咪唑基)-4-羟基苯基}马来酰亚胺酸， N-{3-(2-苯并咪唑基)-4-乙酸酯基苯基}和马来酰亚胺N-{3-(2-苯并咪唑基)-4-羟基苯基}马来酰亚胺，在基本荧光发射团上分别引入了羧酸基；酯基；双键活性基团。

Simultaneously we prepared benzimidazolines with two methods by the reducton of benzimidazolium salts with NaBH_4 and Grignard addition with benzimidazolium salts. Thus we provided a new biomimic synthetic method for 9 kind of tetrahydro-β-carboline starting from carboxylic aicd and halid. A convenient synthetic method for preparing tetrahydro-β-carboline was provided.

本文以1，3-二甲基苯并咪唑碘盐和2-取代的1，3-二甲基苯并咪唑碘盐为原料，采用了NaBH_4还原和Grignard试剂加成两种方法，制备了9种1，3-二甲基苯并咪唑烷和2-取代的1，3-二甲基苯并咪唑烷作为四氢叶酸辅酶一碳单元转移新模型，在酸性条件下，以色胺作为接受一碳转移的亲核试剂，完成9种四氢-β-咔啉类化合物的新合成方法研究。

Simultaneously we prepared benzimidazolines with two methods by the of reduction benzimidazolium salts with NaBH_4 and Grignard addition with benzimidazolium salts. Thus we provided a new biomimic synthetic method for 13 kind of tetrahydroisoquinoline starting from carboxylic aicd and halid, gave a new idea of the synthesis for new drugs.It can make many kind ofβ-carboline alkaloids which have bioactivity to antibacterium, antivirus and antitumor to start from 1,2,3,4-tetrahydro -β-carboline.

本文以1，3-二甲基苯并咪唑碘盐和2-取代的1，3-二甲基苯并咪唑碘盐为原料，采用了NaBH_4还原和Grignard试剂加成两种方法，制备了13种1，3-二甲基苯并咪唑烷和2-取代的1，3-二甲基苯并咪唑烷作为四氢叶酸辅酶一碳单元转移新模型，在酸性条件下，以2-(3，4-二甲氧基苯基)乙胺作为接收一碳转移的亲核试剂，完成了13种重要的四氢异喹啉类化合物的新合成方法研究。

与苯并咪唑相关的网络解释 [注：此内容来源于网络，仅供参考]

benzimidazole：苯并咪唑

主营产品及业务:三唑、咪唑系列:1,2,3-苯骈三氮唑(苯并三氮唑)、甲基苯骈三氮唑、甲基苯骈三氮唑钠盐、苯骈三氮唑钠(BTA-S)咪唑系列:咪唑(Imidazole)、2-甲基咪唑( 2-Methylimidazole)、2-乙基咪唑(2-Ethylimidazole)、苯并咪唑(Benzimidazole)、2-巯基苯并咪唑

benzimidazole：苯并咪唑,间(二)氮茚

benziloyl | 二苯乙醇酰基 | benzimidazole | 苯并咪唑,间(二)氮茚 | benzimide | 苯甲亚胺

5-Nitro benzimidazole：5-硝基苯并咪唑

5-氰吲哚 5-cyanoindole | 5-硝基苯并咪唑 5-Nitro benzimidazole | 5-硝基间苯二甲酸 5-Nitroisophthalic acid

1-Ethyl-2-Mercapto benzimidazole：1-乙基-2 巯基苯噻唑

9,10-二溴蒽 9,10- dibromo anthracene | 1-乙基-2巯基苯噻唑 1-Ethyl-2-Mercapto benzimidazole | 5-硝基苯并咪唑 5-Nitro benzimidazole

benzoglyoxaline; benzimidazole：苯并咪唑

邻苯二甲醇 benzoglycol | 苯并咪唑 benzoglyoxaline; benzimidazole | 双(二苯甲)醚 benzohydro ether; benzohydryl ether

metal-containing benzimidazole complex：苯并咪唑金属配合物

双金属氰化物络合物催化剂:double metal cyanide complex | 苯并咪唑金属配合物:metal-containing benzimidazole complex | 铝:Manganese

Laser photocoagulation to fix the eye and a high doseof benzimidazole to kill the worms：激光光凝治疗眼球 大剂量的苯并咪唑杀虫

They attack his eyeand the muscles surrounding it,making... | Laser photocoagulation to fix the eye and a high doseof benzimidazole to kill the worms.|激光光凝治疗眼球 大剂量的苯并咪唑杀虫 | Wait a min...

benzofuran; coumarone：苯并呋喃;熏草咔;熏草质;香豆咔;香豆质

苯并呋喃;熏草咔;熏草质;香豆咔;香豆质 benzofuran; coumarone | 邻苯二甲醇 benzoglycol | 苯并咪唑 benzoglyoxaline; benzimidazole

benzodiazine：苯并二嗪,酞嗪

benzimidazole 苯并咪唑 | benzodiazine 苯并二嗪,酞嗪 | benzoin 苯偶姻,安息香

benzodiazine：苯并二

benzimidazole 苯并咪唑 | benzodiazine 苯并二 , | benzoin 苯偶姻,安息香