- 更多网络例句与胶质型的相关的网络例句 [注:此内容来源于网络,仅供参考]
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The main collagens in skin are type I and III. In this research, total collagens were separated from rat skin by enzymatic digest and acetum methods. The collagens were denatured at 60℃ and digested with trypsin. Characteristic peptides typical for collagen type I and III were identified with high performance liquid chromatography/mass spectrometry.
哺乳动物皮肤真皮中胶原蛋白含量约为70%,主要为是I型、III型胶原蛋白,本实验利用稀酸溶解和酶法提取了大鼠皮肤中的总胶原蛋白,将胶原蛋白粗提品在60℃变性后用胰蛋白酶进行降解,液相色谱/质谱联用法分析了两种胶原蛋白的特征多肽,利用特征多肽比较了不同生长期大鼠皮肤中I型和III型胶原蛋白相对含量。
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The positive expression of Slit2 located in the cytoplast on oligodendrocyte and astrocyte.The positive cells were found at 3d after spinal cord injury, reached peak on 7d after injury, declining after 14d. The change of Slit2 was correlative with the rehabilitation and regeneration of the axon on the forepart period.
免疫组织化学检测:Slit2蛋白定位于星型胶质细胞和少突胶质细胞的胞浆,呈棕黄色染色,于脊髓损伤后第3 d出现,阳性细胞逐渐增多,于脊髓损伤后第7 d,Slit2阳性表达的细胞数达到高峰并趋于稳定,伤后第14 d开始逐渐下降,呈一过性增高。
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Objective To explore whether the toxic effects on the primary cultured astroglia would be induced by different arsenicals.
目的 观察不同砷化物对原代培养星型胶质细胞的毒性作用。
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In the cytosol preparations, nimodipine inhibited the iNOS enzymatic activity induced by LPS +〓 in mouse astroglia cells with an 〓 value of 0.036±0.003mM and nNOS activity in mouse neurons with an 〓 value of 0.047±0.003mM, but did not affect the eNOS activity in bovine cerebral endothelial cells.
在体外培养细胞制备的匀浆液,尼莫地平抑制由LPS+〓诱导的星型胶质细胞的iNOS活性,〓为0.036±0.003mM,同时还抑制神经元的nNOS活性,IC50为0.047±0.003mM,但对牛脑微血管内皮细胞的eNOS活性无明显影响。
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Methods Samples of the infundibular septum from 22 patients with TOF and 8 patients without cardiovascular disease and collagen system disease as control were studied. Collagen was determined by biochemical methods, Pro α mRNA, Pro α mRNA levels were determined by dot blot hybridization.
用生化方法定量分析了22例法乐四联症患者和8例非心血管及胶原系统疾病尸检者的右室心肌间质中的胶原含量和Ⅰ、Ⅲ型胶原比值,以及用斑点杂交法测定法乐四联症患者右室心肌间质Ⅰ、Ⅲ型前胶原基因mRNA的表达。
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Bone marrow-derived mesenchymal stem cells are capable of chondrogenesis, making them a possible source of cells for injectable cartilage tissue engineering. There exist different ideas on the ability of mesenchymal stem cells's chondrogenesis in monolayer culture. Because of this, the effect of adult rabbit's bone marrow-derived mesenchymal stem cells chondrogenesis in monolayer culture was studied. The mesenchymal stem cells was isolated from adult rabbit's bone marrow and monolayer cultured. TGF-β1, Vit-C and Dexamethasone were used. Immunohistochemistry analyses and histological staining of H-E, Methylaniline blue and Alcian blue were performed to identify the expression of collagen type Ⅱ and cartilage associated matrix. The results showed that the induced cells expressed and produced collagen type Ⅱ and cartilage associated matrix. This suggests that the differentiation of adult rabbit's marrow-derived mesenchymal stem cells into chondrocyte in monolayer culture is feasible and may be induced by TGF-β1, Vit-C and Dexamethasone.
骨髓基质干细胞的软骨分化潜能使其可能成为可注射组织工程化软骨研究的种子细胞,为探讨体外培养的骨髓基质干细胞在平面诱导条件下软骨分化的可行性,我们进行下列实验:获取并体外平面培养成体兔骨髓基质干细胞,应用TGF-β〓、Vit-C和地塞米松对其软骨分化诱导,诱导后的骨髓基质干细胞行细胞爬片组织学和Ⅱ型胶原免疫组化,结果证实,诱导后骨髓基质干细胞可分泌Ⅱ型胶原,组织学染色可见类似于软骨细胞,由此证明体外培养的骨髓基质干细胞在平面诱导条件下可以软骨分化,其软骨诱导因子为TGF-β〓、Vit-C和地塞米松。
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Results: ApoD was observed positively expressed in type2 astrocytes and oligodendrocytes from O2A lineage, while it was not expressed in type1 astrocytes from T1A lineage. Accordingly, we can verify the phenomenon found in the study of T1A and T2A gene different expression profile that ApoD mRNA was highly expressed in T2A and lowly expressed in T1A. Conclusion: It can be concluded that lipid metabolism related genes such as ApoD play important roles in the generation and differentiation of O2A lineage, which closely correlate with internal mechanism of lipid metabolism in the brain and myelogenesis.[Key words]astrocyte(T1A, T2A); oligodendrocyte; O2A lineage; apolipoproteinApoD
我们已采用基因芯片技术在mRNA水平研究两型星形胶质细胞的基因表达谱差异,发现ApoD在2型星形胶质细胞中差异高表达,故本文拟用激光共聚焦双重免疫荧光标记技术进一步在蛋白质水平观察ApoD在体外分化成熟的两型星形胶质细胞以及少突胶质细胞中的表达情况,以期为我们深入研究ApoD等脂代谢相关基因在脑内脂质代谢和神经髓鞘发育机制中所起的作用提供有用的实验依据,依此探讨胶质细胞发生和分化的信号机制。
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However, no significant differences were shown between the cell cultures treated with pentavalent methylated arsenicals and control cultures in reduced rates of alamarBlue and morphological observation at the highest levels of exposure.
另一方面,暴露最高1 000 μmol/L 5价甲基砷和二甲基砷的星型胶质细胞的AlamarBlue还原力及细胞形态与对照组比较未见明显差异。
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In Part 1 of our research, BGSCs were sorted through immunomagnetic beads marking by CD133 and cultured in vitro, and character as a stem cell was identified by stem cell markers (CD133 and Nestin) and differentiated cell markers [ microtubule-associated protein 2(MAP2), glial acidic fibrillary protein and myelin basic protein] , ultrastructure observing with electron microscopeand engrafting to severe combined immunodeficiency mice for tumorigenesis test. The results were as following: Only a small subset of CD133+ glioma cells in glioma cell lines and fresh specimens from various pathologic grade could express stem cell markers CD133 and Nestin, view ultrastructure of a stem cell and be capacity of serial passage in culture. These CD133+ cells possese a marked capacity for multipotent differentiation and could differentiate into tumor cells expressing MAP2,β-TubulinⅢ, GFAP and MBP; When engrafted into SCID mice, they can generate and form tumors that phenotypically resembl the tumor from the patient.
在本课题中,在第一部分实验中采用以CD133为标志的免疫磁珠法从人脑胶质瘤组织和细胞株中分离脑胶质瘤干细胞并进行体外培养,通过免疫荧光技术检测干细胞标志物CD133、Nestin,诱导分化后检查分化细胞标志物MAP2、GFAP、MBP以及电镜超微结构观察和移植SCID鼠致瘤实验,对其干细胞特性加以鉴定,得到如下结果:不同病理分级的新鲜胶质瘤标本和胶质瘤细胞株中存在一小部分CD133+的胶质瘤细胞,能表达干细胞的标志物CD133和Nestin,符合干细胞的超微结构特点,体外培养能连续传代;具有多向分化潜能:诱导分化后能产生MAP2、β-TubulinⅢ、GFAP、MBP染色阳性的细胞;移植SCID鼠后能形成与亲本肿瘤表型一致的移植瘤。
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BHLH repressors suppress bHLH activators and promote maintenance of progenitors and generation of glial cells.
抑制型bHLH转录因子促进视网膜干细胞状态的维持和出生后视网膜胶质细胞的分化。
- 更多网络解释与胶质型的相关的网络解释 [注:此内容来源于网络,仅供参考]
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Pilocytic astrocytoma:毛细胞型星形细胞瘤
毛细胞型星形细胞瘤(pilocytic astrocytoma)多见于10岁左右儿童和青少年,起源于胶质细胞的前体细胞. 本文作者曾诊断1例成人毛细胞型星形细胞瘤患者,现报道如下. 1临床资料患者,男性,31岁. 4年前出现头部持续胀痛,伴有头晕、恶心,时有呕吐,无发热.
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FN:纤维连接蛋白
其典型病理特征是肾小球基底膜(GBM)增厚, ECM主要是纤维连 接蛋白(FN)、 层粘连蛋白(LN)和IV型胶原(ColⅣ)积聚增加所 致的系膜基质增多、系膜区扩张, 最后导致了弥漫性肾小球硬化, 故又称 糖尿病性肾小球硬化症.
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glia cell:神经胶质细胞
神经胶质细胞(glia cell)被称为大脑中的"支持细胞". 研究人员在10月出版的>上报告说,因为表达中出现的一种变异干扰了神经传递素的传输,这种细胞与小脑脊髓干运动失调症第七型(Spinocerebellar ataxia type 7,
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ln:层粘连蛋白
其典型病理特征是肾小球基底膜(GBM)增厚, ECM主要是纤维连 接蛋白(FN)、 层粘连蛋白(LN)和IV型胶原(ColⅣ)积聚增加所 致的系膜基质增多、系膜区扩张, 最后导致了弥漫性肾小球硬化, 故又称 糖尿病性肾小球硬化症.
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vitreous:玻璃体
1.玻璃体的结构特点和成分玻璃体(vitreous)是一种特殊的粘液性胶样组织,呈透明的凝胶状态,由H型胶原纤维网支架和交织在其中的透明质酸分子构成. 在玻璃体基部和视网膜前的皮质,胶原和透明质酸的浓度最大. 干扰两者及其相互作用的任何因素,
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Chordoid glioma of the third ventricle:第三脑室的脊索瘤样胶质瘤
Astroblastoma 星形母细胞瘤 9430 /3 | Chordoid glioma of the third ventricle 第三脑室的脊索瘤样胶质瘤 9444 /1 Ⅱ | Angiocentric glioma 血管中心型胶质瘤 9431 /1 Ⅰ
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lipocyte:脂细胞
贮脂细胞(lipocyte)是一种存在于肝窦周围的细胞,在正常肝脏中,贮脂细胞的主要功能是贮存及代谢视黄醇,在肝纤维化形成过程中,贮脂细胞是细胞外问质成分(除V型胶原外)的主要来源,不仅合成分泌胶原,还合成与分泌其他的非胶原性细胞外间质成分,
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microglia:小神经胶质
神经胶质细胞包括好几种不同的型态,其中有小神经胶质(microglia). 小神经胶质保护脑部不受感染,并去除废物和死亡的细胞. 但是,巨噬细胞在血液中感染爱滋病毒,并把爱滋病毒带入脑部,因此,神经胶质细胞也受到感染.
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Volvox:团藻(属)
(2)团藻属(Volvox)属于团藻目. 春夏两季常见生于淤积的浅水池沼中. 植物体是由数百至上万个衣藻型细胞组成的球形群体,衣藻型细胞排列在球体的表面,空心球体内充满胶质和水. 有的种有胞间连丝,逐步过渡到多细胞的个体.
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epidemic encephalitis B:乙型脑炎
(二)脑桥肿瘤(pontile tumor) 以胶质瘤多见,病情呈渐进性加重,随着肿瘤的发展可出现小脑压迫症状,晚期脑积水明显而表现恶心、呕吐等颅压增高症状. (三)流行性乙型脑炎(epidemic encephalitis b) 突然起病的发热、头痛、呕吐、脑膜刺激症状及血清补体试验阳性.