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However, the use of topical corticosteroids has not been adequately studied.
然而，使用外用皮质肾上腺类脂醇的效果，却没有足够的研究证明。
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In the 188 patients with extensive bullous pemphigoid,topical corticosteroids were superior to oral prednisone (p=0.02), with one-year survival rate 76% vs. 58%, disease control at three weeks 99% vs. 91%, and severe complication rate 29% vs.
188位广泛性大水疱性类天疱疮患者中，外用皮质肾上腺类脂醇的效果优於口服prednisone（p＝0.02），二者的年生存率分别为76％及58％，三周疾病控制率分别为99％及91％，而严重并发症发生率则分别为29％及54％。
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Feb. 4, 2002 -- People with bullous pemphigoid no longer need to endure the potential side effects of oral corticosteroids, based on a French study reported in the Jan. 31 issue of The New England Journal of Medicine .
2002年2月4日──1月31日《The New England Journal of Medicine》杂志上发表的一篇法国的研究报道，患有大水疱性类天疱疮的患者，不必再忍受口服皮质肾上腺类脂醇所可能导致的副作用。
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In the 153 patients with moderatebullous pemphigoid, outcome was similar inthe groups receiving topical or oral steroids, but the total number of days of hospitalization and the number of severe complications were lower in patients treated topically.
153位中度大水疱性类天疱疮患者中，接受外用皮质肾上腺类脂醇与口服皮质肾上腺类脂醇治疗的两组，治疗效果类似。但在使用外用皮质肾上腺类脂醇的患者，总住院日以及严重并发症的数目都较低。
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"Topical corticosteroid therapy is effective forboth moderate and severe bullous pemphigoid and is superiorto oral corticosteroid therapy for extensive disease," write Pascal Joly, MD, PhD, from the University of Rouen in France, and colleagues."Topical corticosteroids should be considered the standard treatment for patients with extensive bullous pemphigoid."
外用皮质肾上腺类脂醇治疗对於中度及严重大水疱性类天疱疮都很有效，对於广泛性大水疱性类天疱疮，其效果优於口服皮质肾上腺类脂醇，」法国鲁昂大学的Pascal Joly医师，PhD及其同事写道：「应该考虑将外用皮质肾上腺类脂醇作为广泛性大水疱性类天疱疮治疗的黄金标准。
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In a randomized, multicenter trial, 341 patients with moderate or extensive bullous pemphigoid received large doses of high-potency topical corticosteroids -- either topical clobetasolpropionate cream (40 g per day) or oral prednisone (0.5 mg perkilogram of body weight per day for those with moderate diseaseand 1 mg/kg/day for those with extensive disease)-- applied over their entire body.
在此次追踪多中心的试验中，341位中度或广泛性大水疱性类天疱疮患者接受大剂量较强外用皮质肾上腺类脂醇全身治疗──使用外用clobetasol propionate乳剂（40g/日）或者口服prednisone（中度患者0.5mg/千克体重/日，重度患者1mg/千克体重/日）。
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Corticosterone test system：肾上腺酮检测系统
862.1195 肾上腺皮质类脂醇检测系统 C orticoids test system | 862.1200 肾上腺酮检测系统 Corticosterone test system | 862.1210 肌氨酸检测系统 Creatine test system
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Osteomalacia：骨软化(症)
⑴肾上腺皮质功能低下 即往6个月以内、2周以上接受类脂醇激素(steroidhormone)者,发生肾上腺皮质激素分泌减少,此类病人可因轻微的外科创伤而致休克. 骨疾患:患有骨疏松症(osteoporosis)、骨软化症(osteomalacia)、骨硬化症(osteoselerosis)以及颌骨病变者.