羟氨基

基本解释 (translations)

amidoxyl  ·  hydroxamino

与羟氨基相关的网络例句 [注：此内容来源于网络，仅供参考]

Based on the mechanism of coupling reaction,the reaction of melt metallocene-based Poly(Ethylene-α-Octene) initiated by dicumyl peroxide was studied at elevated temperature in oscillatory shear flow field.

以苯胺、环氧丙烷为原料制备了N，N 二(2 羟丙基)苯胺，然后NHPPA与对硝基苯胺通过重氮偶合反应制备了一种具有推拉电子结构的偶氮化合物4 硝基 4′ N，N 二(2 羟丙基)氨基偶氮苯。

The charomatographic conditions of separation and direct dermination of benzophenone-4(MS40), salizyle acid sodium, salol, benzophenone-3(M40), octyl dimethyl PABA(6007), butyl methoxy dibenzoyl methane(1789), octyl methoxyl cinnamate and octyl salicylate(587) from u-Bondapak C18 Column were studied with methanol-water-THF as elution. A HPLC method for these compounds was founded.

研究了用甲醇-四氢呋喃-水作为流动相，从C18柱上分离和测定羟苯甲酮-5-磺酸(MS40)、水杨酸钠、水杨酸苯酯、羟苯甲酮(M40)、对-二甲酸氨基苯甲酸-2-乙基己酯(6007)、4-叔丁基-4-甲氧基二苯甲酸甲烷(1789)、对-甲氧基肉桂酸-2-乙基己酯、水氧酸-2-乙基己酯(587)等8种紫外线吸收剂的色谱条件，建立了用HPLC测定上述物质的方法。

METHODS 5-amino-1-hydroxyethyl pyrazole-4-carboylic acid was synthesized through condensation of ethyl cyanoacetate and triethyl orthoformate followed by one-pot methodology of cyclization,hydolysis.

方法原甲酸三乙酯与氰乙酸乙酯缩合，然后和羟乙基肼经环合、水解等一锅法合成5-氨基吡唑-4-甲酸，然后在亚硫酸钠存在条件下加热脱羧得到5-氨基-1-羟乙基吡唑。

When pumped with 800 nm laser irradiation, 2 {4 [2 (4 dimethylamino phenyl vinyl] phenyl} ethylamino ethanol and 2 {4 [2 (4 diethylamino phenyl vinyl] phenyl} ethylamino ethanol show strong two photon induced blue fluorescence at 436 and 440 nm respectively, while DMANHAS and 4 nitro benzoic acid 2 {4 [2 (4 diethylamino phenyl vinyl] phenyl} ethylamino ethyl ester exhibit no fluorescence.

在800 nm的飞秒脉冲激光激发下，反式-4-(N-羟乙基-N'-乙基氨基)-4'-二苯乙烯和反式-4-(N-羟乙基-N'-乙基氨基)-4'-二苯乙烯均发出较强的蓝紫色上转换荧光，荧光峰分别位于436和440 nm，而DMANHAS和反式-4-[N-(乙氧基羰基-4-硝基苯基)-N'-乙基氨基]-4'-二苯乙烯没有荧光。

Methods: According to the mechanism of cough reflex, the c-fibres's role in the respiratory system, and the principle of isosterism. Here, a peripheral antitussive LD was regarded as a lead compound. Amino functional groups, as substituents at the 1-hydroxy group of the racemate of LD, were introduced into the structure of the molecule. These novel compounds were confirmed by 1H-NMR, MS spectrum. Their antitussive activities were studied on mice in sequential method. The EDT50, the stimulating time that caused cough by NH3 on half of mice, were measured. Then could caculated the ratio R between the EDT50 of the treated groups and control group.

根据咳嗽反射的机制及C-纤维在呼吸系统的作用，以外周镇咳药左羟丙哌嗪为先导化合物，依据电子等排原理，在其结构中引入氨基以取代羟丙哌嗪分子中1位的羟基，设计一系列未见报道的化合物（01-15）；并采用了一条适宜的路线进行合成，通过1H-NMR、MS确证结构；采用&序贯法&实验进行新化合物的镇咳活性研究，动物模型采用氨水引咳小鼠，获得引致半数小鼠咳嗽的氨水刺激时间（EDT50）及给药组EDT50与对照组的比值R。

Three part of research works had been carried out in the dissertation. The first part: a kind of multidentate amine modified silica gel was synthesized through the following steps:(1) introduce the amino groups onto the surface of silica-gel by the treatment of surface silanol groups withγ-aminopropyl trimethoxy silane;(2) michael addition of excess trihydroxymethyl propyl triacrylate to amino groups on the silica gel surface;(3) amidation of the unreacted double bonds of TMPTA on the surface of TMPTA modified silica gel with diethylenetriamine;(4) the multidentate amine modified silica gel was finally obtained by the reaction of amino groups on the surface of DETA modified silica gel with double bond of butyl acrylate.

本论文进行了三部分研究工作，第一部分：通过多步反应对硅胶进行改性合成了一种多齿胺改性硅胶配体，合成过程如下：1通过γ-氨丙基三甲氧基硅烷与硅胶表面的硅羟基反应，使硅胶表面带有氨基；2利用硅胶表面氨基与过量的三羟甲基丙烷三丙烯酸酯发生Michael加成反应；3利用二乙烯三胺与TMPTA改性硅胶表面未反应的双键发生反应使硅胶表面氨基化；4最后用丙烯酸正丁酯与DETA改性硅胶表面氨基充分反应成功合多齿胺改性硅胶配体。

Objective To establish the determination method of cefadroxil in healthy volunteers plasma. Methods Plasma protein was precipitated by perchloric acid (10%), and paraaminobenzoic acid was used as internal standard.

目的 建立用内标法测定人血浆中头孢羟氨苄浓度的HPLC-UV方法方法用10％高氯酸直接沉淀血浆蛋白，以对氨基苯甲酸内标，测定血浆中头孢羟氨苄的浓度。

On the basis of these principles and requirements,in this paper,a new modifier has been synthesized from pyromellitic dianhydride and thiosemicarbazide by the nucleophilic addition of anhydride,the cyclization of acyl thiosemicarbazide in alkaline solution,and the N-hydroxymethylation of the triazole-thione.

本文根据这一思路，以均苯四甲酸二酐和氨基硫脲为起始原料，通过酸酐的亲核加成反应、酰氨基硫脲的碱性环化反应、三唑硫酮环的N-羟甲基化反应合成出了一种新的N-羟甲基三唑硫酮酸改性剂。

N-(2-hydroxyethyl)-glucamine was dehydrogenated to 6-(2-droxyethyl) amino-6-deoxy-a-L-sorbofiuanose the key intermediate of miglitol by the resting cells of Gluconobater oxydans Gouv2007 through aeration. 6-(2-Droxyethyl) amino-6-deoxy-a-L-sorbofiuanose was hydrogenated catalyticlly to miglitol. In the transformation of N-(2-hydroxyethyl)-glucamine to miglitol, the transformation rate was 77.3%.

氧化葡萄糖酸杆菌Gouv2007的静息细胞在通气下氧化N-羟乙基葡糖胺脱氢生成米格列醇的前体物质6-脱氧－6-羟乙基氨基－α-L-呋喃山梨糖，再催化加氢生成米格列醇，对从N-羟乙基葡糖胺生成米格列醇的底物转化率为77.3%。

The effects and mechanism of GABAergic neurons, NOergic neurons, opioid peptide and cyclic adenosine monophosphate in the nucleus reticularis thalami on sleep-wakefulness cycle of rats and the effects and mechanism of the 5-HTergic nerve fibers project from the nucleus raphes dorsalis to RT on sleep-wakefulness cycle of rats were investigated with the methods of brain stereotaxic, nucleus spile, microinjection and polysomngraphy.1. The effects of GABAergic neurons in RT on sleep-wakefulness cycle of rats1.1 Microinjection of 3-mercaptopropionic acid (3-MP, a kind of glutamate decarboxylase inhibitor) into RT. On the day of microinjection, sleep only decreased a litter. On the second day, sleep marked decreased and wakefulness marked increased. On the third and fourth day, sleep and wakefulness stages resumed to normal.1.2 Microinjection of gamma-amino butyric acid (GABA 1.0μg) into RT enhanced sleep and reduced wakefulness compared with control; while microinjection of L-glutamate (L-Glu, 0.2μg) decreased sleep and increased wakefulness; microinjection of bicuculline (BIC, 1.0μg), a GABAA receptor antagonist, enhanced wakefulness and reduced sleep; microinjection of baclofen (BAC, 1.0μg), GABAB receptor agonist, had the same effects as GABA.2. The effects of NOergic neurons in RT on sleep-wakefulness cycle of rats2.1 Microinjection of L-arginine (L-Arg, 0.5μg) into RT decreased sleep compared with control, but there were on statistaical difference between L-Arg group and control; while microinjection of sodium nitroprusside (SNP, 0.2μg), a NO donor into RT, sleep marked decreased and wakefulness marked increased. Microinjection of nitric oxide synthase inhibitor, N-nitro-L-arginine (L-NNA, 2.0μg) into RT enhanced sleep and reduced wakefulness.2.2 After simultaneous microinjection of L-NNA (2.0μg) and SNP (0.2μg) into RT, SNP abolished the sleep-promoting effect of L-NNA compared with L-NNA group; after simultaneous microinjection of L-NNA (2.0μg) and L-Arg(0.5μg) into RT, we found that L-NNA could not blocked the wakefulness-promoting effect of L-Arg.3. The effects of opioid peptide in RT on sleep-wakefulness cycle of rats3.1 Microinjection of morphine sulfate (MOR, 1.0μg) into RT increased wakefulness and decreased sleep compared with control; while microinjection of naloxone hydrochloride (NAL, 1.0μg), the antagonist of opiate receptors, into RT, enhanced sleep and reduced wakefulness.3.2 After simultaneous microinjection of MOR (1.0μg) and NAL (1.0μg) into RT, the wakefulness-promoting effect of MOR and the sleep-promoting effect of NAL were not observed compared with control.4. The effects of cAMP in RT on sleep-wakefulness cycle of rats Microinjection of cAMP (1.0μg) into RT increased sleep and decreased wakefulness compared with control; microinjection of methylene blue (MB,1.0μg) into RT enhanced sleep and reduced wakefulness compared with control.5. The effects of the 5-HTergic nerve fibers project from DRN to RT on sleep-wakefulness cycle of rats5.1 When L-Glu (0.2μg) was microinjected into DRN and normal sodium (NS,1.0μg) was microinjected into bilateral RT. We found that sleep was decreased and wakefulness was increased compared with control; when L-Glu (0.2μg) was microinjected into DRN and methysergide (MS,1.0μg), a non-selective 5-HT antagonist, was microinjected into bilateral RT, We found that sleep was enhanced and wakefulness was reduced compared with L-Glu group.5.2 When p-chlorophenylalanine (PCPA, 10μg) was microinjected into DRN and NS (1.0μg) was microinjected into bilateral RT, We found that sleep was increased and wakefulness was decreased compared with control; microinjection of 5-hydroxytryptaphan (5-HTP, 1.0μg), which can convert to 5-HT by the enzyme tryptophane hydroxylase and enhance 5-HT into bilateral RT, could block the effect of microinjection of PCPA into DRN on sleep-wakefulness cycle.

本研究采用脑立体定位、核团插管、微量注射、多导睡眠描记等方法，研究丘脑网状核(nucleus reticularis thalami，RT)中γ-氨基丁酸(gamma-amino butyric acid ，GABA)能神经元、一氧化氮(nitrogen monoxidum，NO)能神经元、阿片肽类神经递质、环一磷酸腺苷(cyclic adenosine monophosphate，cAMP)及中缝背核(nucleus raphes dorsalis，DRN)至RT的5-羟色胺(5-hydroxytryptamine，5-HT)能神经纤维投射对大鼠睡眠-觉醒周期的影响及其作用机制。1 RT内GABA能神经元对大鼠睡眠-觉醒周期的影响1.1大鼠RT内微量注射GABA合成关键酶抑制剂3-巯基丙酸(3-MP，5μg)，注射当天睡眠时间略有减少，第二日睡眠时间显著减少，觉醒时间明显增多，第三、四日睡眠和觉醒时间逐渐恢复至正常。1.2大鼠RT内微量注射GABA受体激动剂GABA( 1.0μg)后，与生理盐水组比较，睡眠时间增加，觉醒时间减少；而RT内微量注射L-谷氨酸(glutamic acid， L-Glu， 0.2μg)后，睡眠时间减少，觉醒时间增加；RT内微量注射GABAA受体阻断剂荷包牡丹碱(bicuculline，BIC，1.0μg)后，睡眠时间减少，觉醒时间增加；RT内微量注射GABAB受体激动剂氯苯氨丁酸(baclofen，BAC，1.0μg)后，产生了与GABA相似的促睡眠效果。2 RT内NO能神经元对大鼠睡眠-觉醒周期的影响2.1大鼠RT内微量注射NO的前体L-精氨酸(L-Arg，0.5μg)后，与生理盐水组对比，睡眠时间略有减少，但无显著性意义；而RT内微量注射NO的供体硝普钠(Sodium Nitroprusside，SNP，0.2μg)后可明显增加觉醒时间，缩短睡眠时间；微量注射一氧化氮合酶抑制剂L-硝基精氨酸(L-arginine，L-NNA，2.0μg)后，引起睡眠时间增多，觉醒时间减少。2.2大鼠RT内同时微量注射L-NNA(2.0μg)和SNP(0.2μg)后与L-NNA组比较发现SNP逆转了L-NNA的促睡眠作用；RT内同时微量注射L-NNA(2.0μg)和L-Arg(0.5μg)后，与L-NNA(2.0μg)组比较发现L-Arg可以增加觉醒而缩短睡眠，其促觉醒作用未能被NOS的抑制剂L-NNA所逆转。3 RT内阿片肽对大鼠睡眠-觉醒周期的影响3.1大鼠RT内微量注射硫酸吗啡(morphine sulfate，MOR，1.0μg)后与生理盐水组对比，睡眠时间减少而觉醒时间增加； RT内微量注射阿片肽受体拮抗剂盐酸纳洛酮(naloxone hydrochloride，NAL，1.0μg)后与生理盐水组比较，睡眠时间增加而觉醒时间减少。3.2大鼠RT内同时微量注射MOR(1.0μg)和NAL(1.0μg)后，与生理盐水组对比，原有的MOR促觉醒效果和NAL的促睡眠效果都没有表现。4 RT内环一磷酸腺苷信使对大鼠睡眠-觉醒周期的影响大鼠RT内微量注射cAMP(1.0μg)后与NS(1.0μg)组比较，睡眠时间增多而觉醒时间减少；RT内微量注射亚甲蓝(methylene blue，MB，1.0μg)后，与NS组比较，睡眠时间增多而觉醒时间减少。5中缝背核投射到丘脑网状核的5-羟色胺能神经纤维对大鼠睡眠-觉醒周期的影响5.1大鼠DRN内微量注射L-Glu(0.2μg)，同时在双侧RT内微量注射NS (1.0μg)后，与对照组(DRN和双侧RT注射NS， 0.2μg)比较，睡眠时间减少，觉醒时间增多；大鼠DRN内微量注射L-Glu(0.2μg)，同时在双侧RT内微量注射二甲基麦角新碱(methysergide， MS， 1.0μg )后，与对照组(DRN注射L-Glu 0.2μg，双侧RT注射NS 1.0μg)比较，睡眠时间增多，觉醒时间减少。5.2大鼠DRN内微量注射对氯苯丙氨酸(p-chlorophenylalanine，PCPA，10μg)，同时在双侧RT内微量注射NS (1.0μg)后，与对照组(DRN和双侧RT注射NS， 1.0μg)比较，睡眠时间增多，觉醒时间减少；大鼠DRN内微量注射PCPA(10μg)，产生睡眠增多效应后，在双侧RT内微量注射5-羟色胺酸(5-hydroxytryptaphan ， 5-HTP， 1.0μg )后，与对照组(DRN注射PCPA 10μg，双侧RT注射NS 1.0μg)比较，睡眠时间减少，觉醒时间增多。

与羟氨基相关的网络解释 [注：此内容来源于网络，仅供参考]

Deg：二羟乙基甘氨酸

氨基羧酸代表品种是乙二胺四乙酸(EDTA)、氮川三乙酸(NTA)、二乙基三胺五乙酸(DTPA);羟氨基羧酸中有羟乙二胺四乙酸(HEDTA)和二羟乙基甘氨酸(DEG);羟基羧酸中有葡萄酸、柠檬酸、酒石酸、草酸等.

hydroxylamine hydrochloride：盐酸羟胺

化合物如赖氨酸、苯胺、谷氨酰胺(glutamine),盐酸羟胺(hydroxylamine hydrochloride)、对氨基苯甲酸、氨基乙酸和其它官能基团如羰基清除剂,可阻止醛类与明胶的反应从而抑制交联.

overdose：超剂量

由该器械所获得的测定结果可用于醋氨酚超剂量(overdose)的诊断和治疗. (a) 标识. 氨基羟丁基卡那霉素A检测系统是预期用于测定血清和血浆中氨基羟丁基卡那霉素A(一种氨基糖苷类(aminoglycoside)抗生素药物)的器械.

Phenylalanine：苯氨基丙酸

关于 苯酮尿症 的百科小常识...苯酮尿症(phenylketonuria) 简称PKU 此疾病为一种罕见的遗传性疾病 起因为苯氨基丙酸(phenylalanine)这种氨基酸无法被完全代谢所导致;缺乏丙酮酸羟化酶 苯丙氨酸只能靠转氨生成苯丙酮酸 病人尿中排出大量苯丙酮酸.

Spermine tetrahydrochloride：二氨基联精胺盐酸盐

113348-540 3-脱氧腺苷 3 - deoxyadenosine | 306-67-2 二氨基联精胺盐酸盐 Spermine tetrahydrochloride | 7365-45-9 4-羟乙基哌嗪乙磺酸 4 - hydroxyethyl piperazine ethanesulfonic acid

acyl methyl taurine：(酰基)甲基氨基乙磺酸

acyl isethionic salt 乙酰基羟乙磺酸盐 | acyl methyl taurine (酰基)甲基氨基乙磺酸 | adamantane 金刚烷

amidoxime：偕胺肟 偕胺肟

amidoxalyl氨基草酰 | amidoxime偕胺肟 偕胺肟 | amidoxyl羟氨基

amidoxyl：羟氨基

amidoxime偕胺肟 偕胺肟 | amidoxyl羟氨基 | amidozoi磺胺甲异噻唑

hydroxamino：羟氨基

hydroxamicacid用羟肟酸 | hydroxamino羟氨基 | hydroxcyprogesteronecaproate羟孕酮己酸酯

acyl isethionic salt：乙酰基羟乙磺酸盐

acyl 酰(基) | acyl isethionic salt 乙酰基羟乙磺酸盐 | acyl methyl taurine (酰基)甲基氨基乙磺酸