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Objective To investigate the clinical features, causes of blindness and diagnosis of Vogt Koyanagi Harada syndrome Methods The data of 157 patients with VKH syndrome were reviewed and analyzed Patients were carefully examined with slit lamp, ophthalmoscope, three mirror lens, fundus fluorescein angiography, indocyanine green angiography and HLA typing Results Headache was noted in 73 5% of these patients Simultaneous involvement of both eyes occurred in 80 8% of these patients Chroiditis,papilledema and edema of the retina adjacent to the optic nerve were noted in 100% of these patients in the posterior uveitis stage, whereas recurrent granulomatous anterior uveitis (98 4%),"sunset glow" fundus (95 8%) and Dalen Fuchs nodules (71 2%) were the common ocular findings in the recurrent anterior uveitis stage The common causes of blindness were papillitis, exudative retinal detachment and complicated cataract in the posterior uveitis stage, anterior uveal involvement stage and its recurrent stage Poliosis (36 3%) and alopecia (35 0%) were the most common extraocular findings Early irregular patches of fluorescence, followed by localized hyperfluorescent spots were the typical findings of FFA Dilation of choroidal vessels and leakage of ICG from the choroidal vessels were the common ICGA findings The prevalence of HLA DR4 and HLA DRw53 in patients (54 9% and 71 8% respectively) was significantly higher than that in controls (14 7% and 38 2% respectively) Conclusions VKH syndrome is characterized by chroiditis, papillitis or neuroretinitis in the posterior uveitis stage, followed by a generalized uveitis with a typical recurrent granulomatous anterior uveitis Extraocular findings and relevant examinations including FFA, ICGA and HLA typing are helpful to the diagnosis of VKH syndrome
目的探讨Vogt-Koyanagi-Harada综合征患者的临床特征、盲目原因及诊断等有关问题。方法对在1996年1月至2000年12月间就诊资料完整的157例VKH综合征患者进行回顾性分析,并对裂隙灯、眼底镜、三面镜、荧光素眼底血管造影(fundus fluorescein angiography,FFA)、吲哚青绿血管造影(indocyanine green angiography,ICGA)及人类白细胞抗原分型等检查结果进行分析。结果 VKH综合征最常见的前驱症状为头痛(102例,73.5%),双眼同时患病118例(80.8%);后葡萄膜炎期眼部主要表现为脉络膜炎、视乳头及附近视网膜水肿(100.0%);前葡萄膜炎反复发作期眼部表现为复发性肉芽肿性前葡萄膜炎(128例,98.4%)、晚霞状眼底改变(95.8%)及Dalen-Fuchs结节(71.2%);后葡萄膜炎期、前葡萄膜受累期及前葡萄膜炎反复发作期导致盲目的主要原因分别为视乳头炎、视网膜脱离及并发性白内障;毛发变白(36.3%)及脱发(35.0%)是最常见的眼外表现;炎症活动期FFA典型表现为斑驳状高荧光,ICGA发现脉络膜血管扩张、通透性增高等改变;VKH综合征患者HLA-DR4及HLA-DRw53的阳性率(54.9%及71.8%)显著高于正常对照组(14.7%及38.2%)。结论 VKH综合征患者在后葡萄膜炎期眼部典型表现为双侧脉络膜炎、视乳头炎或神经视网膜炎,随后出现以反复发作的肉芽肿性前葡萄膜炎为特征的全葡萄膜炎。眼外症状及相关的辅助检查包括FFA、ICGA 及HLA分型等有助于VKH综合征的诊断。
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nodular dermal vasculitis in lower extremities are often seen clinically in middle-age women, and are evoked by many causes. Some laboratory examinations have abnormal outcomes and we think these are related with autoimmune reactions of nodular dermal vasculitis. We can make diagnosis with clinical character of erythema and nodose lesions in lower extremities, laboratory examinations and histopathology inspection. Antibiotics, non- Steroid anti-inflammatory drugs, anti-tubercle drugs and corticosteroids are effective drugs.
结节型皮肤血管炎多发于中年女性;结节型皮肤血管炎病因复杂,可能是由于细菌、真菌、病毒、结核、药物等所引起,也可为某些全身性疾病的皮肤表现;实验室指标异常改变可能与疾病免疫反应有关;结节型皮肤血管炎诊断以双下肢红斑结节性损害的临床特点,结合实验室及组织病理学检查可确诊分型;结节型皮肤血管炎针对病因选用抗生素、非甾体抗炎药、抗结核药、皮质类固醇激素等治疗有效。
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Abstract] Objective To explore the diagnostic value of MSCT angiography on the polyarteritis nodosa.
目的 探讨多层螺旋CT血管成像诊断腹腔结节性多动脉炎(polyarteritis nodosa,PAN)的应用价值。
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Abstract] Objective To explore the diagnostic value of MSCT angiography on the polyarteritis nodosa.Methods The MSCT data of 16 sases with PAN were retrospectively analysed.
目的 探讨层螺旋CT血管成像诊断腹腔结节性多动脉炎(polyarteritis nodosa,PAN)的应用价值方法回顾性分析16例PAN的MSCTA表现。
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Objective To explore the diagnostic value of MSCT angiography on the polyarteritis nodosa. Methods The MSCT data of 16 sases with PAN were retrospectively analysed.
目的 探讨多层螺旋何血管成像诊断腹腔结节性多动脉炎(polyarteritis nodosa, PAN)的应用价值,方法回顾性分析16例PAN的MSCTA表现。
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Systemic vasculitis vascular inflammation is the main pathological changes in a class of inflammatory diseases, including aortoarteritis, giant cell arteritis, and polyarteritis nodosa arteritis, Wegener's meat, such as swollen teeth.
系统性血管炎是以血管炎症反应为主要病理改变的一类炎性疾病,包括大动脉炎、巨细胞动脉炎、结节性多动脉炎、韦格氏肉牙肿等。
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Orchiectomy for testicular torsion showed acute vasculitis consistent with polyarteritis nodosa.
随后患者因睾丸扭转急诊行单侧睾丸切除术,术后病理检查见同结节性多动脉炎病理类型相一致的急性血管炎。
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Numerous case reports featuring its off-label use suggest the drug could be helpful in treating hidradenitis suppurativa, pyoderma gangrenosum, Sweet's syndrome, cutaneous sarcoidosis, pemphigus, systemic vasculitides, multicentric reticulohistiocytosis and stomatitis.
许多以非常规用药为特色的病例报告指出,该药物有助于治疗化脓性汗腺炎、坏疽性脓皮病、Sweet综合征、表皮结节病、天疱疮、系统性血管炎、多中心网状组织细胞增多症和口腔炎。
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Results:One hundred and twenty one cases (2.5%) with disease of cervical artery were found among them. Eightynine cases with intima-media thickening and 32 casas with plaque formation were diagnosed. Its coincidence was up to 100%. Detection rate of thyroid disease lesion was up to 9.2% in 428 cases of 4655 cases health screening. More nodoles goiter were found and next to thyroid cyst,thyroid adenomas,hyperthyroidism,thyrditis and thyroid cancer.
结果: 4 655例中,经超声筛查颈部血管病变121例,检出率为2.5%,其中单纯颈、椎动脉内膜-中层厚度增厚89例,合并粥样硬化斑块32例,诊断符合率为100%;筛查甲状腺疾病428例,检出率为9.2%,发病以结节性甲状腺肿居多,其次为甲状腺囊肿、甲状腺腺瘤、甲状腺功能亢进、甲状腺炎、甲状腺癌等,诊断符合率为82%。
- 更多网络解释与结节性血管炎相关的网络解释 [注:此内容来源于网络,仅供参考]
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fibrinoid degeneration:纤维蛋白样变性
⑸ 纤维蛋白样变性:纤维蛋白样变性(fibrinoid degeneration)是指纤维蛋白渗透入通常伴有变性改变的胶原组织或沉积于受损的血管壁及周围,使其呈现有折光的嗜伊红均质的外观,见于红斑狼疮、结节性多动脉炎等.
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nodular episcleritis:结节性巩膜外层炎
phlyctenular pannus 泡性血管翳 | nodular episcleritis 结节性巩膜外层炎 | episcleritis periodica fugax 一过性周期性巩膜外层炎
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erythema nodosum:结节性红斑
结节性红斑(erythema nodosum)是以皮肤血管炎和脂膜炎为病理基础,以下肢疼痛性结节为临床特点的一种皮肤病,可见于任何年龄,但好发于中青年女性,春秋季多见.
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polyarteritis nodosa:结节*多动脉炎
摘要:结节多动脉炎(polyarteritis nodosa)是一种累及中、小动脉全层的炎症和坏死性血管炎,随受累动脉的部位不同,临床表现多样,可仅局限于皮肤(皮肤型),也可波及多个器官或系统(系统型),以肾脏,心脏,神经及皮肤受累最常见.
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Test for polyarteritis nodosa:查结节性多动脉炎
You and big love,biopsy of blood vessel from around the heart.|你和博爱 活检心脏周围的血管 | Test for polyarteritis nodosa.|查结节性多动脉炎 | You...|你嘛...
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venule:小静脉
可出现血管麻痹性扩张,静脉瘀血,其通透性增加,血浆渗人组织间隙而引起水...(1)结节性多动脉炎(经典的结节性动脉炎):中动脉的及小动脉的坏死炎症,不伴有肾小球肾炎或微小动脉(arteriole)、毛细血管(capillary)或微小静脉(venule)炎症.
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hyphema:前房积血
如果血管破裂,红细胞外溢,即产生前房积血(hyphema). 4.虹膜纹理不清:虹膜炎时,虹膜血管扩张随之水肿浸润,色泽变暗,虹膜表面纹理不清,在肉芽肿性虹膜睫状体炎时,可望见虹膜结节,有深层和浅层两种. 深层者位于瞳孔缘呈半透明小灰色团者称koeppew结节,
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phlyctenular pannus:泡性血管翳
trachomatous pannus 沙眼性血管翳 | phlyctenular pannus 泡性血管翳 | nodular episcleritis 结节性巩膜外层炎
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periarteritis:动脉周围炎
主要累及小动脉和中等大小动脉,也可累及毛细血管和静脉. 此病在文献中也被称为动脉周围炎(periarteritis)或多血管炎(polyangiitis). 结节性多动脉炎过去是全身性血管炎的总称,随着人们认识的加深,目前已将其视为一种独特的临床类型,
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perichondritis:软骨膜炎
此病在文献中曾被称为多发性软骨炎(polychondritis)、软骨膜炎(perichondritis). 结节性多动脉炎(polyarteritis nodosa)是一种以坏死性血管炎为特征的累及多系统、多器官的少见的疾病. 主要累及小动脉和中等大小动脉,也可累及毛细血管和静脉.