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Odoquinazolin-4(3H)-one,7-methyl-4(3H)-quinazolinone,7-bromoquinazolin-4(3H)-one were synthesized by using anthranilic acid、2-amino-5-nitrobenzoic acid、2-amino-4-nitrobenzoic acid,6-nitro--4(3H)-quinazoline-one、o-amino-terephthalic acid, 2-amino-4-hydroxy benzoic acid、2-amino-5-bromo-benzoic acid、2-amino-5-iodine acid,1、4-butynediol、L-glutamine、isatin anhydride、formamide as starting materials and utilizing microwave-assisted synthetic approach.
本文利用微波辅助合成的方法,以邻氨基苯甲酸、2-氨基-5-硝基苯甲酸、2-氨基-4-硝基苯甲酸、邻氨基对苯二甲酸、2-氨基-4-羟基苯甲酸、2-氨基-5-溴苯甲酸、2-氨基-5-碘苯甲酸、5-甲基-2-氨基苯甲酸等为原料与甲酰胺反应,以及以1,4-丁炔二醇、L-谷氨酰胺与靛红酸酐反应,共合成了13个喹唑啉酮衍生。。。
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Besides, the derivatives were synthesized successfully by the similar acid binding agent system, such as tris(4-nitrophenyl) thiophosphate, tris(4-toluene)thiophosphate. The derivative of maleic anhydride was synthesized by the simple method, and its yield was above 90%.
采用类似的缚酸剂体系成功地合成了硫代磷酸三(4-硝基苯)酯、硫代磷酸三(4-甲基苯)酯,并用简单的方法合成了硫代磷酸三(4-氨基苯)酯的马来酸酐衍生物——硫代磷酸三(4-马来酸氨基苯)酯,产率达90%以上。
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Furthermore, through molecular structural design, we have also synthesized stable dual functional diphenylether polymer intermediates of ABB' types possessing ortho-dicarboxylic at one aromatic ring and diamine groups at another beginning from Xylenol and 1-Chloro-3,4-dinitrobenzene as the raw materials.
中文摘要本研究应用自氧化法与氢化法两反应,成功而有劾地制备出芳香族含酸酐及二胺基之官能基单体,并进一步经由分子结构设计,从3,4-二甲苯酚及1-氯-3,4-二硝基苯为原料,转化合成出安定性高带有羧基与双胺基双官能基之堑新ABB'型二苯醚中间体,并成功地应用此中间体从事自聚合反应,而合成分歧状聚醚亚醯胺高分子。
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The para-/ortho- product isomer ratio is 6.2 for the nitration of chlorobenzene at 18℃ for 8h with n/n(NH4NO3)=5. The para-/ortho- product isomer ratio is 14.0 for the nitration of bromobenzene at 0℃ for 8h with n/n(NH4NO3)=5. The pars-product, p-nitrobromobenzene, from the nitration of bromobenzene in [HSO4] under 0℃ precipitates with 98% purity, which facilitates the separation of the pure isomert.
其中氯苯在18℃下反应8h,三氟乙酸酐/硝酸铵为4时产物的对邻比达到6.2,而溴苯在0℃下反应8h,TFAA/硝酸铵为5时产物的对邻比可达到14.0,并且生成的对硝基溴苯可以从反应液中析出,得到对硝基溴苯含量为98%的产物。
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The optimum reaction conditions were: at present of acetic anhydride, a stoichiometric quantity of nitric acid, at room temperature for 40 minutes. Nitration of chlorobenzene gave a,50% yield of mononitro compounds, and an ortho-para isomer ratio 0.20 in product distribution of chlorobenzene mononitration.
结果表明:硅钨酸催化性能较好,催化剂载体以纳米二氧化硅最好,反应条件中醋酸酐用量是主要影响因素;SiW_(12)O_(40)~(4-)/纳米SiO_2催化剂具有强对位选择性:在醋酸酐存在下,氯苯与等当量的硝酸室温下反应40分钟,氯苯一硝化产物中邻/对硝基氯苯异构体的质量比达0.2,产率可达50%。
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Papain was modified using different anhydrides. The average ratio of modified-NH2 was tested by a trinitrobenzenesulfonic acid method. The native and modified papain samples were purified by dialysis and their structures were characterized by UV and IR.
用不同酸酐对木瓜蛋白酶进行化学修饰,以三硝基苯磺酸法测定修饰酶的平均氨基修饰度,对修饰前后的木瓜蛋白酶分别纯化并通过UV-vis和IR对其结构进行了表征。
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nitric anhydride:硝酸酐; 五氧化二氮
Nitrex A.G. of Zurich;苏黎世氮肥出口有限公司;; | nitric anhydride;硝酸酐; 五氧化二氮;; | nitric oxide catalysis;氧化氮催化作用;;
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nitrous anhydride:亚硝酸酐,亚硝酐
nitrous acid ester 亚硝酸酯 | nitrous anhydride 亚硝酸酐,亚硝酐 | nitrous compound 亚硝酸化合物
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Nitrex A.G. of Zurich:苏黎世氮肥出口有限公司
Nitrazepam;硝西泮;硝基安定;; | Nitrex A.G. of Zurich;苏黎世氮肥出口有限公司;; | nitric anhydride;硝酸酐; 五氧化二氮;;