- 更多网络例句与白蛋白化合物相关的网络例句 [注:此内容来源于网络,仅供参考]
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Based on the previous literatures, the following major innovation works were carried out in this dissertation:(1) The derivatization reaction conditions of ephedrine and pseudoephedrine with sensitive derivation reagent in aqueous system were studied and two new methods were developed for the assay of them by microemulsion electrokinetic chromatography and micellar electrokinetic chromatography with LIF detection. The sensitivity and analysis times were greatly improved compared with the previous reports;(2) A new method of CZE with indirect LIF detection was developed for the simultaneous determination of six coumarin compounds (esculin, esculetin, isofraxidin, genistein, naringin and sophoricoside) with fluorescein as the probe. The proposed method enlarges the application range of LIF detector, and provides new approach for the analysis of certain compounds difficult to derivatize;(3) Based on the above research, an MEKC with indirect LIF detection method for the simultaneous determination of adenine and guanine in DNA extracts from fungus, maize and soybean was established;(4) A new method for the investigation of the complexes formed between human serum albumin and ampicillin sodium under the simulated physiology conditions using laser light scattering technique was developed.
该论文在综述前人工作的基础上,开展了如下未见文献报道的创新性的研究工作:(1)使用灵敏的衍生试剂对麻黄碱和伪麻黄碱在水体系中的衍生反应条件进行了系统研究,建立了微乳电动色谱-激光诱导荧光检测法和胶束电动色谱—激光诱导荧光检测法测定麻黄碱和伪麻黄碱的灵敏分析新方法,与以前的报道相比,灵敏度和分析时间均有很大改善;(2)使用荧光素钠作为背景荧光试剂,建立了同时分析测定六种黄酮类化合物(秦皮甲素、秦皮乙素、异秦皮定、染料木素、柚皮苷和槐角苷)的毛细管区带电泳—间接激光诱导荧光检测新方法,扩大了激光诱导荧光检测的应用范围,对难衍生化合物的分离分析提供了一种新思路和新途径;(3)以荧光素钠作为背景荧光试剂,建立了一种用于同时测定食品提取DNA中的腺嘌呤和鸟嘌呤含量的胶束电动色谱—间接激光诱导荧光检测新方法;(4)用动态和静态激光散射法研究了模拟生理条件下人血清白蛋白与氨比西林钠盐相互作用所形成的复合物,为药物分子与蛋白质的相互作用、药代动力学等的研究提供了一种新思路。
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Using progesterone and bovine serum albumin as model compounds respectively, fluorescent labeled small molecule hapten and large molecule antigen were prepared.
1以孕酮和牛血清白蛋白为模型化合物,制备了小分子半抗原和大分子抗原的荧光标记物,研究了标记物的抗原活性和光谱性质,结果表明标记物是有效的毛细管电泳免疫分析试剂;制备了抗体F〓片段,研究了其抗体活性,结果表明F〓片段比整个抗体更适合作为毛细管电泳的免疫分析试剂。
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This thesis deals with the investigation on the chemical constituents of Dioscorea Opposite Thunb and studys the interactions between 5,7-dihydroxy-4′-methoxy flavanone,-epicatechin and bovine serum albumin using fluorescence, electrochemical method ,UV absorption and NMR spectroscopy. The main contents are as follows: Chapter 1: Study of the chemical constituents in Dioscorea opposita Thunb 1. Two methods were used to methylate the fatty acid in Dioscorea opposita Thunb.
本文在前人的工作基础上对我省道地药材-怀山药饮片中的化学成分进行了系统的研究;同时利用核磁共振方法、电化学分析法、荧光光谱法、紫外光谱法分别研究了两种天然酚性化合物5,7-二羟基-4′-甲氧基二氢黄酮,(--表儿茶素与牛血清白蛋白之间的相互作用,主要内容如下:一。
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According to the fluorescence measurement results from mixed solution, the association constant estimated for thioridazine hydrochloride-BSA binding and the number of the binding site with Scatchard analysis were 1.2×104 L/mol and 0.98, respectively.
将盐酸硫利达嗪与牛血清白蛋白以不同比例混合并在37 ℃下培养,以流动注射透析采样技术从混合液中分离出游离盐酸硫利达嗪,在线氧化为强荧光化合物后测定其浓度;应用Scrathard方程分析所测数据,求得盐酸硫利达嗪和牛血清白蛋白的结合常数为1.2×104 L/mol,结合位点数为0.98;根据热力学参数推断,盐酸硫利达嗪与牛血清白蛋白之间以疏水作用力为主;进一步基于荧光猝灭现象和Fster非辐射能量转移理论,得到盐酸硫利达嗪小分子与牛血清白蛋白之间的能量转移效率( E =0.497)和结合距离( r 0=3.27 nm)。
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A series of study methods which can not research in this field begin to exert important affection. On the basis of the previous research, the following major innovative work was carried out in this dissertation.(1) Several methods including fluorescence spectra, CD and FT-IR specta methods were used to study the interaction of isoquinoline alkaloid、isoflavones and Rhein with serum albumin, and the results from every method was in good agreement;(2) The binding constants、the numbers of binding site、the binding region and the interaction force involving in the interaction of drugs and serum albumin were confirmed by Scatchard equation and Vant Hoff equation.
基于研究生物大分子与小分子相互作用具有极其重要的意义,本博士论文在前人工作的基础上,主要进行了以下几方面的创新性研究:(1)利用荧光光谱法、圆二色谱法、红外光谱法以及分子模拟等多种方法相结合研究了异喹啉类生物碱,异黄酮类化合物以及大黄酸与人血清白蛋白的相互作用,获得了准确一致的信息;(2)根据Scatchard方程和Vant Hoff方程详细研究计算了异喹啉类生物碱以及大黄酸与蛋白质结合机理包括结合常数、结合位点数、结合区域、结合力。
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The interaction of tributyltin, the main components of antifouling paint of ships, and its degradation products of monobutyltin and dibutyltin with human serum albumin was investigated by ultraviolet, fluorescence and circle dichromism spectra. The influences of the concentration, acidity, organic solvent such as ethanol and ionic strength on the interaction of butyltin compounds and HSA molecule were examined to find that the interaction of butyltin compounds and HSA was dual.
通过紫外、荧光和CD光谱,研究了船体防污漆中主要防污成分——三丁基锡化合物及其降解产物——一丁基锡和二丁基锡与人血清白蛋白相互作用的方式与程度,考察了浓度、酸度、有机溶剂和离子强度等因素对相互作用的影响。
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Rutin has many physiological activities. It can maintain the resistance of the blood vessel, reduce their osmoses and brittleness, promote proliferation of the cells and prevent the blood cells from agglutination.
因此,小分子化合物与牛血清白蛋白(Bovine serum albumin,BSA)和人血清白蛋白(Human serum albumin,HSA)相互作用的研究已经成为了化学生物学中重要的研究课题。
- 更多网络解释与白蛋白化合物相关的网络解释 [注:此内容来源于网络,仅供参考]
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albumin glue:蛋白胶
albumin globulin ratio 白蛋白 球蛋白比 | albumin glue 蛋白胶 | albuminate 白蛋白化合物
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albuminate:白蛋白化合物
albumin glue 蛋白胶 | albuminate 白蛋白化合物 | albuminoid 硬朊
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albuminoid:硬朊
albuminate 白蛋白化合物 | albuminoid 硬朊 | alchemy 炼金术
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conjugate:缀合物
结果表明,高良姜素、山萘酚、槲皮素等三种黄酮化合物能够使牛血清白蛋白的荧光猝灭,各化合物与BSA自发地发生了结合,形成了新的加合物(Adduct)或缀合物(Conjugate).
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gliadin:醇溶蛋白
小麦中所含之蛋白质可分为麦谷蛋白(Glutenin)、醇溶蛋白(Gliadin)、酸溶蛋白(Mesonin)、白蛋白(Albumin)、球蛋白(Globulin)等五种. 碳水化合物为一种有机物之复合体,包括碳、氢、氧三原素,其中氢与氧原子比为2比1,
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albuminiferous:产蛋白的
albuminate 白蛋白化合物;变性白蛋白(曾用名:骗) | albuminiferous 产蛋白的 | albuminimetry 蛋白定量法
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albuminimeter; albuminometer:白蛋白计
"白蛋白化合物","albuminate" | "白蛋白计","albuminimeter; albuminometer" | "白蛋白解(作用)","albuminolysis"
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fat-soluble compound:脂溶性化合物
fat-soluble bilirubin-albumin complex ==> 脂溶性胆红素白蛋白复合物 | fat-soluble compound ==> 脂溶性化合物 | fat-soluble vitamin ==> 脂溶性维生素