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Results Seven known compounds: ocotillol (1), ursolic acid (2), betulin (3), lupeol (4), 1β-hydroxy-lupeol (5),β-sitosterol (6) and sitosterol-4-en-3-one (7) were isolated.
结果 分离得到7个化合物,分别鉴定为:20S,24R-环氧达玛烷-3β,25-二醇(ocotillol, 1)、熊果酸(2)、白桦脂醇(3)、羽扇豆醇(4)、1β-羟基羽扇豆醇(5)、β-谷甾醇(6)、谷甾-4-烯-3-酮(7)。
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Objective To investigate the effects and mechanism of betulin on rats with alcoholic liver disease.
目的:观察白桦脂醇对大鼠酒精性肝损伤的保护作用及其机制。
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Objective To study the antioxidant effects of betulin on alcoholic liver disease in rats.
目的 观察白桦脂醇对大鼠酒精性肝损伤的抗氧化作用。
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It is significant to study the pharmaceutical activities of betulin ,betulinic acid andtheir derivatives and to confirm the relationship between th...
研究白桦脂醇、白桦脂酸及其衍生物的药理活性,确定结构与活性间的关系,对筛选出更为经济、有效的药物成分具有重要意义。
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They are obtained from avariety of botanical sources and betulinic acid can be easily prepared from the more plentifulprecursor betulin in a simple two-step process.
它们可以从丰富的植物资源中获得,白桦脂酸也可由更丰富的前体白桦脂醇经简单的两步制得。
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Betulin has obviously protective effects on alcoholic liver injury in rats.The mechanism may be the induced decrease of lipid peroxide.
白桦脂醇能抑制酒精诱导脂质过氧化反应对肝组织的损伤,对酒精性肝损伤有明显的保护作用。
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Methods Rats were randomly divided into six groups: normal group,alcoholic liver disease model group,betulin low-dose group,betulin middle-dose group,betulin high-dose group and positive control group.
将SD大鼠随机分为6组,正常组和酒精性肝病模型组、白桦脂醇低、中、高剂量组和阳性药物对照组。
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The hepatic injuries of rats in the highdose betulin group were recovered obviously.
高剂量白桦脂醇还能明显改善由酒精引起的肝组织脂肪样变和坏死。
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Betulin,betulinic acid and many of theirderivatives exhibit great promise as bioactive agents for the treatment of HIV infection andcancer.
白桦脂醇、白桦脂酸及其衍生物作为生物制剂在 HIV 和癌症治疗方面表现出了巨大的潜能。
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High-dose of betulin has obviously protective effects on alcoholic liver injury in rats,the mechanisms probably contribute to reducing lipid peroxide and reducing fatty sediment in liver.
高剂量白桦脂醇对酒精性肝损伤有明显的保护作用,其作用机制可能为抗氧化、清除自由基代谢产物,抑制脂质过氧化反应;调节血脂、减少脂肪在肝脏的沉积。
- 更多网络解释与白桦脂醇相关的网络解释 [注:此内容来源于网络,仅供参考]
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Betulin:白桦脂醇
根含延胡索酸(fumaric acid),白桦脂醇(betulin),D-甘油酸(D-glyceric acid)和聚β-羟基丁酸(poly-β-hydroxybutyric acid). (责任编辑:admin)
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Betulin:桦木脑
左旋水苏碱 Betonicine | 桦木脑 Betulin | 白桦脂醇 Betulin
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Betulin:桦木脑 桦木醇 白桦脂醇
betulenol | 三甲基亚甲基双环十一碳烯醇 | betulin | 桦木脑 桦木醇 白桦脂醇 | betuloside | 桦木糖苷 白桦苷
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Betulin diacetate:桦木脑二乙酸
白桦脂醇 Betulin | 桦木脑二乙酸 Betulin diacetate | 桦木酸 Betulinic acid
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Betulinic acid:白桦脂酸
前者包括白桦 脂酸(betulinic acid),白桦脂醇等;后者包括oleanonic acid, maslinic acid等. 到目前为止,从酸枣仁中分离的皂甙有9种,主要有酸枣仁 皂甙(jujuboside) A、B等,属于达玛甾烷型, 是由酸枣仁皂甙元(jujubogenin)所衍生的皂甙.
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Crocin I:番红花素
Tangeretin 桔皮素 98% | Crocin I 番红花素 98% | Betulin 白桦脂醇 98%