- 更多网络例句与痛觉过敏的相关的网络例句 [注:此内容来源于网络,仅供参考]
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In this study we evaluated the effects of IV ketorolac on an experimental model of deep tissue hyperalgesia using IM capsaicin.
在这项研究中,我们评估了静注酮洛来克对肌注辣椒素导致深部组织痛觉过敏的试验模型的效应。
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It is evidenced that ectopic spontaneous activities in injured DRG are the signal source of spontaneous pain and hyperalgesia.
已有证据表明受损背根节神经元的异位自发放电是引起自发痛与痛觉过敏的信号来源。
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The concept of preemptive analgesia is to decrease the incidence of hyperalgesia and allodynia by reducing central sensitization.
预先镇痛是通过防止中枢敏感化来降低伤害性刺激引起的痛觉过敏和异常痛觉。
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Levels of NGF are increased in inflamed tissues, and this effect may contribute to the role of NGF in inflammatory hyperalgesia.
组织炎症时NGF与炎症过程中痛觉过敏的发生机制有关。
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METHODS: Ninety-two patients with diabetic neuropathy, postherpetic neuralgia, or postsurgical/posttraumatic neuropathic pain with allodynia, hyperalgesia, or pinprick hypesthesia were randomly assigned to receive one of four creams (placebo, 2% amitriptyline, 1% ketamine, or 2% amitriptyline-1% ketamine combined).
92名出现痛觉超敏、痛觉过敏或针刺感觉减退的糖尿病神经病变、疱疹感染后神经痛或手术后/外伤后神经性疼痛患者被随机分组,分别使用下列四种霜剂中的一种进行治疗:安慰剂、2%阿米替林、1%氯胺酮或2%阿米替林+1%氯胺酮联用。
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BACKGROUND: Chronic pain, including hyperalgesia and algesthesia paresthesia, is pathological phenomenons making the patients felt unendurable and lacking of clinical treatments.
背景:慢性痛包括痛觉过敏和痛觉感觉异常,是患者感到难以忍受和临床缺乏治疗手段的一种病理现象。
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Objectives A rat model sciatic nerve crush injury was reproduced in rat, and behavioral changes, pain threshold, thermal withdrawal latency and the changes in c-fos expression in cornu dorsale medullae spinalis were examined, and the relationship between peripheral nerve regeneration and hyperpathia was explored.
目的 建立大鼠坐骨神经挤压模型,观察其神经恢复过程中行为学、机械痛阈值、热缩足反射潜伏期以及脊髓背角c-fos表达(对c-fos表达产物:Fos蛋白阳性的神经元进行计数)的改变,探讨外周神经损伤再生与痛觉过敏的关系。
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In addition, IT injection of the -2 adrenoceptor antagonist, idazoxan (40 g/rat) 10 minbefore clonidine injection completely reversed clonidine'santi hyperalgesic and anti allodynic effects, as well as clonidine'ssuppressive effect on CCI-induced NR1 phosphorylation in thespinal cord dorsal horn.
另外,可乐定可以抑制 CCI 导致的脊髓背侧角 NR1磷酸化,但是在注射可乐定之前10min ,鞘内注射α-2受体拮抗剂咪唑克生(40 g/小鼠),可以完全逆转其对抗痛觉过敏的效果。
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The latedischarges decreased from 9.29 ± 0.97 to 6.71 ± 0.68 with the A-fiberconditioning stimulus increasing from 1 to 5 (n〓8, P〓0. 05).(7) The intervalbetween the conditioning stimulus and test stimulus (C-T interval) wasincreasing, the inhibition tended to plateau off. At shorter time intervalsthe inhibition became more effective. When C-T interval was limited in 50ms,the inhibitory effects was the strongest, here, the late discharges reducedfrom 12.57±1.21to 2.29±0.42 (n=11, P<0. 01).(8) Behavior research showedthat the rat model of snake venom exhibited neuropathic pain with heathyperalgesia, cold and mechanical allodynia, which corresponding to the acuteelectrophysiological findings.
此时轻刷WDR神经元的感受野不能引起其活动改变,但伤害性齿镊夹捏仍可引起WDR神经元放电增多;〓5〓晚成分放电的潜伏期缩短,即宁静期的时程变短,由给蛇毒前的118.83〓3.67ms降至50.72〓1.36ms〓n〓32,P〓0.01〓;〓6〓在正常动物,如果预先给予只激活A纤维的弱条件电刺激〓mA,100μs〓可抑制随后的伤害性检验刺激所诱发的WDR神经元的晚成分放电,当条件刺激个数从1增加至5时,每次伤害性检验刺激所诱发的晚成分放电数从9.29〓0.97个降至6.71〓0.68个〓n〓8,P〓0.05〓;〓7〓固定条件刺激数为1个,当条件刺激与检验刺激之间的间隔增大时,A纤维条件刺激对WDR神经元晚成分放电的抑制作用逐渐减弱,当条件刺激与检验刺激之间的间隔在50 ms以内时,抑制效应最为显著,此时,晚成分放电数由正常时的12.57〓1.21个降至2.29〓0.42个〓n〓11,P〓0.01〓;〓8〓与急性研究中的WDR神经元电活动的变化结果相匹配,利用蛇毒制备的大鼠模型在行为学上表现为热痛觉过敏、冷觉的痛性感觉异常及机械痛觉过敏等慢性痛症状。
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At the same time, most WDR neurons failedto respond to the light brush applied to the receptive fields, but they couldbe intensively excited by the noxious pinch.(5) The latency of the latedischarges was shortened from 118.83 ± 3.67ms to 50.72 ± 1.36ms (n〓32, P〓0. 01).(6) Preceding graded number of A〓fiber conditioning inputs (〓mA, 100 μs) delayed the C-activity evoked by the following nociceptive teststimulus activating both A- and C-fiber applied to the sciatic nerve. The latedischarges decreased from 9.29 ± 0.97 to 6.71 ± 0.68 with the A-fiberconditioning stimulus increasing from 1 to 5 (n〓8, P〓0. 05).(7) The intervalbetween the conditioning stimulus and test stimulus (C-T interval) wasincreasing, the inhibition tended to plateau off. At shorter time intervalsthe inhibition became more effective. When C-T interval was limited in 50ms,the inhibitory effects was the strongest, here, the late discharges reducedfrom 12.57±1.21to 2.29±0.42 (n=11, P<0. 01).(8) Behavior research showedthat the rat model of snake venom exhibited neuropathic pain with heathyperalgesia, cold and mechanical allodynia, which corresponding to the acuteelectrophysiological findings.
此时轻刷WDR神经元的感受野不能引起其活动改变,但伤害性齿镊夹捏仍可引起WDR神经元放电增多;〓5〓晚成分放电的潜伏期缩短,即宁静期的时程变短,由给蛇毒前的118.83〓3.67ms降至50.72〓1.36ms〓n〓32,P〓0.01〓;〓6〓在正常动物,如果预先给予只激活A纤维的弱条件电刺激〓mA,100μs〓可抑制随后的伤害性检验刺激所诱发的WDR神经元的晚成分放电,当条件刺激个数从1增加至5时,每次伤害性检验刺激所诱发的晚成分放电数从9.29〓0.97个降至6.71〓0.68个〓n〓8,P〓0.05〓;〓7〓固定条件刺激数为1个,当条件刺激与检验刺激之间的间隔增大时,A纤维条件刺激对WDR神经元晚成分放电的抑制作用逐渐减弱,当条件刺激与检验刺激之间的间隔在50 ms以内时,抑制效应最为显著,此时,晚成分放电数由正常时的12.57〓1.21个降至2.29〓0.42个〓n〓11,P〓0.01〓;〓8〓与急性研究中的WDR神经元电活动的变化结果相匹配,利用蛇毒制备的大鼠模型在行为学上表现为热痛觉过敏、冷觉的痛性感觉异常及机械痛觉过敏等慢性痛症状。
- 更多网络解释与痛觉过敏的相关的网络解释 [注:此内容来源于网络,仅供参考]
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gate:闸门
后索的上行纤维有侧支进入后角, 这些侧支可调节皮肤感觉(包括痛觉)的传人冲动.有人将后角视为"闸门" (gate),感觉传人冲动在此可发生突触前抑制或 突触前易化(后者是产生痛觉过敏的机制之一); 此闸门也受高位脑下行冲动的影响.
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hyperalgesia:痛觉过敏
值得指出的是闸门学说的实验基础是基于生理状态下脊髓痛觉信息传递机制的研究结果,对病理性"痛觉过敏"(Hyperalgesia)、"触诱发痛"(Allodynia)和自发痛(包括幻肢痛)的解释仍面临挑战,但无论如何,这个学说在推动痛觉研究中意义重大.
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hyperalgesia:痛觉过敏 (名)
hyperaesthesia 神经过敏症; 知觉过敏 (名) | hyperalgesia 痛觉过敏 (名) | hyperalgesic 痛觉过敏的 (形)
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hyperesthesia:感觉过敏
5.感觉过敏(Hyperesthesia)对刺激的敏感性增加,不包括特殊感觉. 感觉过敏主要指各种皮肤的感觉,包括非疼痛性触觉和温度觉以及痛觉;多用于对各种刺激的感觉阈值减低和对正常感觉的刺激反应增强. 感觉异常广义包括痛觉异常和痛觉过敏,
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algesia:痛觉
1.痛觉(algesia) 通常用大头针的针尖以均匀的力量轻刺病人皮肤,让病人立即陈述具体的感受. 为了避免主观或暗示作用,病人应闭目接受测试. 测试时注意两侧对称部位的比较,检查后记录感觉障碍的类型(正常、过敏、减退、消失)和范围.
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algesic,algetic:痛的
\\"痛觉过敏\\",\\"algesia\\" | \\"痛的\\",\\"algesic,algetic\\" | \\"痛觉计\\",\\"algesimeter,algesiometer\\"
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dysesthesia:感觉迟钝
3.感觉迟钝(Dysesthesia)一种自发性或诱发性的不愉快感觉;特殊的病人包括痛觉过敏和痛觉异常. 感觉迟钝总是不愉快的,而感觉异常则不一定不愉快,尽管愉快与不愉快的界限不是非常明显. 但应当区别感觉迟钝是自发性或诱发性.
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hyperalgesic:痛觉过敏的
hyperalgesia 痛觉过敏 | hyperalgesic 痛觉过敏的 | hyperaphia 触觉过敏
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hyperalgesic:痛觉过敏的 (形)
hyperalgesia 痛觉过敏 (名) | hyperalgesic 痛觉过敏的 (形) | hyperbaric 高压的 (形)
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hyperaesthesia:感觉过敏
3 2.3 感觉过敏(hyperaesthesia):表示对于引起正常疼痛的刺激反应性增高,即反应增高,阈值正常. 如这种高敏性是伤害性刺激引起的,则是痛觉过敏. 痛觉过敏和痛觉到错是触物感痛的特殊形式. 触物感痛(dysaesthesia):一种不愉快的异常感觉,