激动药

基本解释 (translations)

excitomotory

与激动药相关的网络例句 [注：此内容来源于网络，仅供参考]

Some animals were vomiting and getting excited when administered the large dosage and medium dosage injection. The blood sugar elevated, the thoracic gland coefficient lowered, the hepatic cells were cloudily swollen in the animals of large dosage group.

高、中剂量组部分大鼠给药时出现呕吐、易激动；高剂量组大鼠血糖升高、胸腺系数下降、肝细胞有轻中度浊肿。

The affected chicks acquired the morphine conditioned place preference more quickly, and maintained it much longer. Experiment 3 showed that during E5-8, injecting delta receptor antagonist naltrindole reversed the learning and memory impairment caused by morphine while delta receptor agonist DPDPE impaired learning and partial memory function. On the other hand, mu opioid receptors had little effect. As for E17-20, given naloxonazine can reverse the increases of susceptibility to morphine, and the mu receptor agonist DAGO cause the increases of susceptibility to morphine. Delta receptors have no effect.

研究结果发现：经过对鸡胚发育不同时间段的吗啡给药，胚胎期发育E5-8阶段给予吗啡的小鸡学习记忆受损最为严重，表现为学习和记忆功能的严重下降；而E17-20时段吗啡给药的小鸡更容易获得吗啡CPP且保持时间更长。E5-8阶段给予delta受体拮抗剂natrindole能够翻转吗啡对学习和记忆的损害作用，并且给予delta受体激动剂DPDPE也损害学习和部分记忆功能，mu受体作用不大。E17-20阶段拮抗mu受体能够抑制成瘾易感性的增加，激动mu受体可以增加小鸡的成瘾易感性，delta受体没有明显作用。

Effective analgesic product has been isolated from Najanaja and it could be the important substitute of morphia because of its higheranalgesic activity and non-addiction.

利用 CHO-μ受体细胞筛选阿片受体激动剂是从中发现新的镇痛剂和戒毒药的便捷方法。

Master the pharmacological action, clinical application and major adverse reaction of pilocarpine and of neostigmine（anti-cholinesterase）.

掌握M 胆碱受体激动药毛果芸香碱、抗胆碱酯酶药新斯的明的作用、应用及主要不良反应。

McGill University - A psychopharmacology study has found that a new class of antidepressant drugs known as serotonin4 (5-HT4) receptor agonists may take effect four to seven times faster than traditional selective serotonin reuptake inhibitors.

麦吉尔大学-精神药理学研究发现，一类新的抗抑郁药称为s erotonin4（ 5 - h t4）受体激动剂可能生效6时5 6倍，速度比传统的选择性血清素再吸收抑制剂的。

Bicyclic compounds containing a phenyl or pyridyl ring fused to a cycloalkyl or heterocyclic ring, to which is attached a 5-membered heterocyclic ring, including pharmaceutically acceptable salts and prodrugs thereof, are agonists of G-protein coupled receptor 40 (GPR40) and are useful as therapeutic compounds, particularly in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.

本发明涉及含有连接在5元杂环上的稠合至环烷基或者杂环的苯基或者吡啶基环的二环化合物，包括其药学上可接受的盐和前药，它们是G蛋白偶联受体40(GPR40)激动剂并且可以用作治疗性化合物，特别是在2型糖尿病和与这些疾病相关的症状中用作治疗性化合物，这些症状包括肥胖病和脂质疾病，比如混合或者糖尿病型血脂异常症、血脂质过多、高胆甾醇血和高甘油三酯血症。

Methods:The self-made potassium chloride monopha- sic action potential recording electrodes(KCI-MAP elec- trodes)were pluged into the canine left anterior ventricu- lar wall,where isoprenalinewas administered through the KCI-MAP electrodes to mimic the increase of local sympathetic nervous tension,monophasic action potentialof the three layers(endocardium,mid-myoeardium and epicardium)at left anterior ventricular wall were re- corded simultaneously before and after Iso been administered.

方法经自制跨室壁氯化钾单相动作电位记录电极(KC1-MAP电极)于左心室前壁局部给予异丙肾上腺素模拟局部交感神经张力增加，记录给药前后三层心肌的单向动作电位，分析动作电位时程、图形特征和跨室壁复极离散度的变化，观察VT的诱发情况和VT发作时室壁激动顺序。

与激动药相关的网络解释 [注：此内容来源于网络，仅供参考]

partial agonist：部分激动药

还有一类药物称为部分激动药(partial agonist)和R结合的亲和力不小,但内在活性有限,α00%,量效曲线高度(Emax)较低. 与激动药同时存在时,当其浓度尚未达到Emax时,其效应与激动药协同,超过此限时则因与激动药竞争R而呈拮抗关系,

partial agonist：部分激动药[剂]

布朗三角图形法|Brown triangle method | 部分激动药[剂]|partial agonist | 部分拮抗药[剂]|partial antagonist

full agonist：完全激动药

可分为完全激动药(full agonist)和部分激动药(partial agonist). (2)拮抗药:能与受体结合,具有较强亲和力而无内在活性(α=0)的药物称为拮抗药. 它们本身不产生作用,但因占据受体而拮抗激动药的效应. 分为竞争性拮抗药和非竞争性拮抗药.

full agonist：完全激动药[剂]

完全蛋白质|complete protein | 完全激动药[剂]|full agonist | 完全培养基|complete medium, CM

adrenergic agonist：肾上腺素能激动药

肾上腺皮质激素类|adrenocortical hormones | 肾上腺素能激动药|adrenergic agonist | 肾上腺素能受体拮抗药|adrenoreceptor antagonist

adrenergic agonist：腎上腺素能激動藥 肾上腺素激动药

adrenergic 腎上腺素能藥 拟肾上腺素药 | adrenergic agonist 腎上腺素能激動藥 肾上腺素激动药 | adrenergic;adrenomimetics 擬腎上腺素劑 拟肾上腺素药

excitomotor：运动功能促进药 兴奋运动的 激动药

excitometabolic促代谢的 | excitomotor运动功能促进药 兴奋运动的 激动药 | excitomotorarea兴奋运动区

excitomotory：兴奋运动的 激动药

excitomotorcenter兴奋运动中枢 | excitomotory兴奋运动的 激动药 | excitomuscular兴奋肌肉的

adrenoceptor agonists：肾上腺素受体激动药

肾上腺素受体激动药(adrenoceptor agonists)是一类能与肾上腺素受体结合并激动该受体,产生与肾上腺素能递质(去甲肾上腺素)作用相似的药物. 肾上腺素受体激动药的基本化学结构为β-苯乙胺,其中肾上腺素、去甲肾上腺素、异丙肾上腺素、多巴胺和多巴酚丁胺的化学结构含有儿茶酚,

cholinoceptor agonists：胆碱受体激动药

胆碱受体激动药(cholinoceptor agonists)可激动胆碱受体. 产生与乙酰胆碱类似的作用. 乙酰胆碱是中枢和外周神经系统的内源性神经递质,其主要释放部位在神经突触和神经效应器接头部位,主要作用为激动毒蕈碱型胆碱受体(M胆碱受体)和烟碱型胆碱受体(N胆碱受体). 前者医'学教育网搜集整理主要分布于副交感神经 ...