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Hydrolyzed collagen which has a protein concentration of around 90-95% and its hydrolyzed structure has a very high absorbing power.
水溶性胶原蛋白具有蛋白质浓度约90-95%,其水溶性的结构有很强的吸收能力。
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We coupled the IgG of monoclonal antibody N34 specific to UK and the Fab of monoclonal antibody SZ-51 specific to the membrane protein GMP-140 of activated platelet. The bispecific antibody (N34 SZ-51) is able to bind UK and plasma-clot simutaneously. It enhanced plasma clot lysis 5 fold by HUK whereas it enhanced plasma clot lysis 38 times by LUK. UK in association with the bispecific antibody didn't decrease the concentration of fibrinogen in the assay supernatants.
利用抗体介导使纤溶酶原激活剂定向到血栓表面,可大大提高其纤溶作用,我们用双功能团试剂将抗尿激酶的单克隆抗体N34的IgG和抗活化血小板膜蛋白GMP-l40的单抗SZ-5l的Fab片段通过二硫键共价偶联,合成的双专一性抗体(N34-SZ-51)既具有血栓亲和性也具有尿激酶亲和性,从而增加了尿激酶对血栓的专一性,使高分子量尿激酶溶栓率提高了5倍,使低分子量尿激酶溶栓率提高了38倍之多,且不影响血浆中纤维蛋白原的含量。
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Carboxypeptidase inhibitor from potato , a special inhibitor of TAFIa, was used to test effect of heparin and hirudin on activation of TAFI.
对尿激酶诱导的纤溶,水蛭素比肝素有更好的间接促纤溶作用,其原因主要是水蛭素能有效抑制再次血凝的发生,减少了尿激酶和纤溶酶原的短暂性耗竭。
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Staphylokinase is a 136-amino acid protein,secreted by certain strains of lysogenesis Staphylococci with thrombolytic potential.
葡激酶是由溶原性葡萄球菌分泌的一种具有潜在溶栓功能的含有136个氨基酸的蛋白质。
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The results indicated that the recA gene showed a remarkable physiological function in the λ lysogenic bacteria. It could induce the λ prophage to enter the lysis cycle from lysogenic state.
结果表明recA基因在溶原菌中表现出明显的生理功能,能使λ原噬菌体从溶原状态进入裂解循环。
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According to one conserved sequences of phage GIL01 from Bacillus thuringiensis,a pair of primers was designed.With overnight cultivations of 35 B.t standard strains and one fermentative strain MZ1 as templates,PCR results showed that 16 strains,which may be lysogenic strains,produced the product with the size about 750 bp as anticipated.
根据苏云金杆菌(Bacillus thuringiensis, B.t)溶原性噬菌体GIL01(GenBank Accession Number: AJ536703)的同源序列设计一对引物,用35株B.t标准菌株和生产菌株MZ1(血清型H3a3b)的过夜培养物作模板,结果有16株菌株包括MZ1能扩增出大小约为750 bp的预期产物,推测这16株菌为溶原菌。
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Among them strain MZ1 had been confirmed a lysogenic strain by indicator strain ZK1 after producing phage plaques induced by Mitomycin C.Two templates of overnight cultivation and its DNA from strain MZ1 were then amplified in the same time with five pairs of primers designed from the same phage,and the same products were obtained,suggesting that strain MZ1 was also confirmed a lysogenic strain by PCR method.
MZ1菌株的过夜培养液与指示菌ZK1(血清型H25)混匀并在双层琼脂上培养12 h后出现了滴度为2×107 pfu的噬菌斑,从而证明生产菌株MZ1确为溶原菌;又以GIL01同源性较高的其它四个基因设计引物,分别以MZ1的培养物及其溶原性噬菌体基因组为模板进行PCR扩增,结果两者得到几乎一致的带型,进一步证明了生产菌株MZ1为溶原菌,说明利用PCR法检测鉴定苏云金杆菌的溶原性是可行的。
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In this research, liposoluble chlorogenic laurate was synthesized by the acylation with lauroy chloride in the existence of alkali catalyst in non-water phase, and yellowish CGL powders with a yield of 81.24% were obtained under the optimal synthesis conditions determined via single-factor tests and orthogonal experiments, that is, carrying out the acylation at 35℃ for 8h with a n:n: n ratio of 1:1:1.5 and with dimethylformamide as the solvating agent and the thinner.
文中对绿原酸进行了改性,即在碱性催化剂催化的条件下使其与月桂酰氯进行非水相的酯化反应,得到了脂溶性的绿原酸月桂酸酯。经过单因素及正交试验,确定了最佳合成条件为:以N,N-二甲基甲酰胺作为溶解、稀释剂,绿原酸/月桂酰氯/三乙胺的摩尔比为1:1:1.5,温度控制在35℃,反应时间8h。
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Increase of PAI-1 level in blood results in reduction of plasmin generation and predisposes to the formation of fibrin thrombus.
当血中PAI-1异常增高时,纤维蛋白溶酶原激活子对纤维蛋白溶酶原的激活作用减弱,因而没有足够量的纤维蛋白溶酶产生,结果纤维蛋白在血管中积聚而形成血栓。
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The enzyme not only directly degraded fibrin clot, but also had the ability of converting pladminogen to plasmin.
该酶既具有纤溶酶作用,又具有激活纤溶酶原的作用。
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Plasminogen Activator:纤溶酶原激活物
的过程称为纤维蛋白溶解,简称纤溶.※ 纤维蛋白溶解系统 纤维蛋白溶解过程 血液生理 纤维蛋白溶解系统: 纤维蛋白溶解系统 纤维蛋白溶解酶原 (plasminogen) ) 纤维蛋白溶解酶 (plasmin) ) 纤溶酶原激活物 (plasminogen activator) ) 纤溶酶原抑制物 (plasminogen inhibitor) ) 由肝,
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Lysogenic bacterium:溶原性细菌
整合在细菌基因组中的噬菌体基因组称为前噬菌体(prophage),带有前噬菌体基因组的细菌称为溶原性细菌(lysogenic bacterium). 前噬菌体偶尔可自发地或在某些理化和生物因素的诱导下脱离宿主菌基因组而进入溶菌周期,产生成熟噬菌体,导致细菌裂解.
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thermoinducible lysogen:热诱导溶原性细菌
thermoduric 耐热的 nàirède | thermoinducible lysogen 热诱导溶原性细菌 | thiamine pyrophosphate 硫胺焦磷酸 liúànjiāolínsuān
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Lysogenic phage:溶原性噬菌体
二是噬菌体感染易感细菌后,其基因与宿主菌染色体整合,多数情况下,不产生子代噬菌体,不引起细菌裂解,但噬菌体DNA能随细菌DNA复制,并随细菌的分裂而传代,称为温和噬菌体(temperate phage)或溶原性噬菌体(lysogenic phage).
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vampire bat:吸血蝠
从南美吸血蝠(vampire bat)唾液中分离出的纤溶酶原激活物(DSPA-al)与纤维蛋白结合后对纤溶酶原的催化活性增加45000倍,比t-PA的作用要强得多. 犬、大鼠、兔和猿猴等动物的实验已证实DSPA-al对纤维蛋白有高度的特异性,不引起纤维蛋白原降解.
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lysogenesis:溶源现象
lysogen 溶源体,溶源菌 | lysogenesis 溶源现象 | lysogenic immunity 溶源性免疫[原噬菌体阻碍另一同类噬菌体基因组的建立]
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Lysogenic conversion:溶原性转换
4.溶原性转换(lysogenic conversion) 是侵入细菌的噬菌体DNA与细菌的染色体发生重组,导致细菌的基因型的改变,获得新的性状. 1.细菌耐药性的概念 细菌耐药性分为固有耐药(intrinsic resistance)和获得性耐药(acquired resistance),
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lysogenic immunity:溶源性免疫[原噬菌体阻碍另一同类噬菌体基因组的建立]
lysogenesis 溶源现象 | lysogenic immunity 溶源性免疫[原噬菌体阻碍另一同类噬菌体基因组的建立] | lysogenization 溶源化
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mycoplasma:支原体
支原体(Mycoplasma)是一类独特微生物,起人类肺炎的支原体主要有支原体属的肺炎支原体和尿素原体属的溶尿素原体,前者引起成人和儿童肺炎.是急性呼吸道感染特别是儿童肺炎常见病因之一,全年各月均有散在病例发生,季节性不明显,
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Prophage:原噬菌体
86、原噬菌体(prophage):某些温和噬菌体侵染细菌后,其DNA整合到宿主细菌染色体中. 处于整合状态的噬菌体DNA称为~~. 87、溶原性细菌:含有原噬菌体的细胞,也称溶原体. 88、转化(transformation):指细菌细胞(或其他生物)将周围的供体DNA,