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The acidity of the decoction of the aconite roots and honeysuckle is the weakest, whereas the aconitine is not restrained.
附子与金银花共煎液的酸性是本实验最低的,但中乌头碱未被抑制。
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Rat glioma cell C6 was infected by the deficiency recombinant retrovirus (named C6TK). The sensitivity of C6TK cells to GCV or ACV increased 450 or 10 times than that of C6 cells respectively. Rat C6 glioma model was successfully built, and SD rats inoculated intracerebrally C6TK cells had normal gliomas. The average survival periods of the rats were about 15 days. However, after treated with ACV, the growth of C6TK tumors obviously regressed, and the survival periods extended to 57.8±8.1 days, especially in rats injected with mixed PA317TK and C6 cells or in situ PA317TK cells, which the tumors nearly disappeared after ACV administration and the survival periods extended to over 120 or 71.4±36.1 days respectively, P<0.001.
结果:构建了带有HSV-tk基因的反转录病毒载体GINaTK,应用脂质体转移方法将GINaTK导入反转录病毒包装细胞PA317,成为产病毒细胞PA317TK,用带有HSV-tk基因的复制缺陷型反转录病毒感染C6细胞,命名为C6TK细胞,对GCV和ACV的敏感性分别高于亲本450倍和10倍;成功地建立了大鼠脑胶质瘤模型,并证实转染细胞C6TK的成瘤效应未改变,存活期约为15天;而经ACV治疗后,含有C6TK细胞的肿瘤生长明显被抑制,大鼠生存期延长为57.8±8.07天,尤其是采用PA317TK细胞混和治疗组和原位治疗组,肿瘤基本消失,大鼠生存期显著延长,混和治疗组存活120天以上,原位治疗组存活至71.4±36.1天。t检验,P值均小于0.001。
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Results: GINaTK retroviral vector containing HSV-tk was constructed and transduced into PA317 retrovirus packaging cell by lipofectin (named PA317TK). Rat glioma cell C6 was infected by the deficiency recombinant retrovirus (named C6TK). The sensitivity of C6TK cells to GCV or ACV increased 450 or 10 times than that of C6 cells respectively. Rat C6 glioma model was successfully built, and SD rats inoculated intracerebrally C6TK cells had normal gliomas. The average survival periods of the rats were about 15 days. However, after treated with ACV, the growth of C6TK tumors obviously regressed, and the survival periods extended to 57.8±8.1 days, especially in rats injected with mixed PA317TK and C6 cells or in situ PA317TK cells, which the tumors nearly disappeared after ACV administration and the survival periods extended to over 120 or 71.4±36.1 days respectively, P <0.001.
结果:构建了带有HSV-tk基因的反转录病毒载体GINaTK,应用脂质体转移方法将GINaTK导入反转录病毒包装细胞PA317,成为产病毒细胞PA317TK,用带有HSV-tk基因的复制缺陷型反转录病毒感染C6细胞,命名为C6TK细胞,对GCV和ACV的敏感性分别高于亲本450倍和10倍;成功地建立了大鼠脑胶质瘤模型,并证实转染细胞C6TK的成瘤效应未改变,存活期约为15天;而经ACV治疗后,含有C6TK细胞的肿瘤生长明显被抑制,大鼠生存期延长为57.8±8.07天,尤其是采用PA317TK细胞混和治疗组和原位治疗组,肿瘤基本消失,大鼠生存期显著延长,混和治疗组存活120天以上,原位治疗组存活至71.4±36.1天。t检验,P值均小于0.001。
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Estatic fears - chapter i edit by hide The feeble leafs decline, Enshrined in downing deep The mourn abandoned plains, Laid down in sombre sleep Misty shades engulf the sky Like past, worn memories The bird's song fills the whispering breeze With autumns melody The lunar pale grim shape At evening's sight renews It's silented wail relieves Repressed thoughts anew I hear the lonesome choir Of fortunes past my way Disdained in fiery weeps Throughout my every day These skies I hail and treasure thee, Most pleasant misery Not pittes thorn I shelter thine Mysterious harmony Draw on most pleasant night Shade my lorn exposed sight For my grief's when shadows told Shall be eased in mist enfold Why should the foolish's hope Thy unborn passioned cry Exhaust unheard Beneath this pleasent sky?
无力的叶子飘落铭记着深深地坠落忧伤放弃了平原躺在了昏暗的睡眠当中模糊地影子吞没了天空就像过去的,破损的记忆鸟儿的歌充斥着飒飒的的微风伴着秋天的旋律月亮苍白的可怕的形状夜晚的景象复始禁默的悲叹被释放被抑制的想法卷土重来我听见命运寂寞的唱诗班经过我的路线用热烈的悲叹蔑视着贯穿着我的每一天我所致敬的这些天空并且珍视的你最快乐的痛苦不是我所庇护的你的荆棘神秘的祥和遮住我所暴漏的孤独的景象当阴影诉说时的我的悲伤应该在模糊的拥抱下减轻为何那些愚蠢的要希望你的未出世尽情的哭泣精疲力尽无人倾听在这片愉快的天空下如果黄昏降临快乐还会远吗
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The group disposed by Acetylspiramycin doesn"t show parallel results; The strip gray scale of exotoxin A decreased gradually with the increasing dosages of Azithromycin and Roxithromycin, which doesn"t show in group disposed by Acetylspiramycin and group PAO-JP2; The strip gray scale of lasR, detected by RT-PCR, decreased gradually with the increasing dosages of Azithromycin, which doesnt show in group PAO-JP2.Conclusions: There were obvious differences between PAO1 and PAO-JP2 in biology characteristics in vitro.
本研究发现大环内酯类药物在生物被膜培养过程中分别处理PAO1、PAO-JP2,结果提示大环内酯类药物(14、15元环)通过对QS系统的影响可有效抑制铜绿假单胞菌生物被膜的形成;通过QS系统有效抑制铜绿假单胞菌的毒力因子的产生,16元环的大环内酯类药物乙酰螺旋霉未见上述结论;lasR基因的反转录结果提示阿奇霉素可在转录水平抑制QS系统发挥其作用。
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In these instances, growth is allowed to continue unhampered for a slightly longer time than is common, or it may be inhibited at a slightly earlier period.
在这些实例里,发展被允许继续下去而未受阻,稍微有点长的时间比是普通的,或者它可能被抑制在一个稍微有点早期的时期。
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Most patients receiving long-term acid suppression therapy for physician-diagnosed PUD in community practice settings are likely to have HP-negative, uninvestigated dyspepsia.
Allison医师及其同事表示,在检验及治疗曾罹患PUD病患的建议指导方针中,假设PUD可以被处理,并且成功的消灭HP可以排除未来治疗及用药的需求,大多数在社区医院经医师诊断为PUD,且接受长期酸抑制治疗的病患,常呈现HP阴性反应,且有未诊断出的消化不良症。
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Results Trastuaumab inhibited cell proliferation, colony formation, and decreased or eliminated the levels of two uncharacterized phospho-proteins ( molar weight about 90 000 and 40 000) in SKBR3 cells shedding high level of HER-2 ECD expression.
结果高HER-2 ECD水平的SKBR3细胞生长及克隆形成率明显被曲妥珠单抗抑制,在相对分子质量为90000和40000左右分别有1条未知磷酸化蛋白明显降低或基本消失,而细胞生长及克隆形成率未受影响的SKOV3细胞中此蛋白无明显变化。
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The binding free energy calculations by the following equation:〓 In first equation, the left parenthesis denotes the absolute free energies associated with complex system G〓 and unbound protein G〓, respectively, while the right parenthesis contains solvated inhibitor G〓 and solvent water G〓.
预测结合自由能的计算公式如下:〓ΔG〓是体系结合自由能,G〓是复合物的绝对自由能,G〓是未结合抑制剂的蛋白质绝对自由能,G〓被溶剂化的抑制剂绝对自由能,G〓溶剂水的绝对自由能。
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The 94-kDa GLase activity was Ca++ dependent, showed maximal activity in the pH 6-8, their activity was inhibited in the presence of 1,10-phenanthroline, and their proenzymes were cleaved and activated after incubation with organomercurial compounds and trypsin.
72kDa蛋白脢,出现於所有检体,包括未被感染的老鼠,94kDa蛋白脢只出现於广东住血线虫感染老鼠脑部。94kDa蛋白脢活性是一种钙离子依赖性,在pH值6-8时具最大活性,在 1,10-phenanthroline存在下,其活性受到抑制,此蛋白酵素元会被有机汞类及胰蛋白脢切断并活化。
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AMA:抗线粒体抗体
对单独使用UDCA反应不完全的患者可考虑联合运用免疫抑制药物如糖皮质激素、甲氨蝶呤及抗纤维化药物如秋水仙碱,但联合用药的有效性还未被证实. ⒉及时去大医院做"自身抗体"检查,若"抗线粒体抗体"( AMA)阳性或M2阳性时,即可确诊.
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lupine:羽扇豆
除此之外,在土豆(Pearce等,1991)、羽扇豆(lupine)(Radlowski等,1997)中已提取到系统素. 但是否在植物中广泛存在还不太清楚. 生理作用 植物被昆虫食害后,系统素从伤害处传遍未受伤害的部分,促进蛋白酶抑制剂基因的活化和转录,
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Unsubdued:未被抑制的
Generation 世代 | Unsubdued 未被抑制的 | Nuclear 核能的