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Among the above symptoms and signs, some of them like cyanosis of lips, purplish tongue, varicose sublingual vein, headache, blackish eyelids, tongue with ecchymosis, blackish complexion, squamous and dry skin, pain on the paralytic limbs, dermorrhagia are the conventional ones, the others like flaccidity of lower extremities, hemianesthesia, dispiritedness, dysphasia, distension of stomach and abdomen are found by us.
当然,其中主要是一些传统的血瘀证症状、体征,如唇色紫暗、舌质紫暗、舌脉曲张、睑下青黑、舌有瘀斑、面色晦暗、肌肤甲错、瘫肢疼痛不移、肌肤青紫/有瘀斑,但也有一些症状和体征是以往并不常作为判断血瘀证的,如下肢肌力减弱、偏身麻木、精神萎靡、言謇失语、脘腹胀满,为脑梗塞血瘀证的诊断增加了新的依据。
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Meanwhile, cyanosis of lips, purplish tongue, varicose sublingual vein, flaccidity of lower extremities, hemianesthesia, headache, blackish eyelids, dispiritedness, tongue with ecchymosis, dysphasia, blackish complexion, squamous and dry skin, pain on the paralytic limbs, dermorrhagia, and distension of stomach and abdomen are more influential symptoms and signs.
同时,在相关的临床症状和体征的多元线性逐步回归分析中发现,唇色紫暗、舌质紫暗、舌脉曲张、下肢肌力减弱、偏身麻木、头痛,睑下青黑、精神萎靡、舌有瘀斑、言謇失语、面色晦暗、肌肤甲错、瘫肢疼痛不移、肌肤青紫/有瘀斑及脘腹胀满对脑梗塞血瘀证诊断的影响较大;将单因素分析有显著性意义的症状、体征变量,代入贝叶斯逐步判别分析,结果发现唇色紫暗、舌脉曲张、爪甲紫暗、偏身麻木、舌质紫暗、言謇失语、睑下青黑、头痛、瘫肢温度降低、下肢肌力下降等对血瘀证的诊断能力较强,而且在随后的交互检验中也显示了较好的稳定性。
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There all is the hypodermic haemorrhage such as double lower limbs to choose Yu spot before cure, uric convention is different the change of degree. 1 · 2 diagnostic basises:? of Dong of Jue of Bei of in the company of has HSP medical history, have haemorrhage dot and Yu spot hypodermically, extend side to see more with double lower limbs, often distributing symmetrically again, size differs, show amaranth, press do not fade, prep above skin,...
治疗前均有双下肢等皮下出血点瘀斑,尿常规不同程度的改变。1·2诊断依据:①肾外表现:有HSP病史,皮下有出血点和瘀斑,以双下肢伸侧多见,常又对称分布,大小不等,呈紫红色,压之不褪色,高于皮肤,。。。
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Adverse events included mild to moderate transient erythema and pain, and mild pinpoint petechiae.
副作用有轻度到中度的短暂红斑、疼痛及轻度的瘀斑。
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Meanwhile, we discussed the founded background of ZIDIANKELI, and we treated the ITP according to the idea"the origin of the disease is the Qi-Deficiency, Blood Stasis run through the course of the disease" and make the principle of the treatmentstrengthening Qi and tonifying the deficiency, removing the blood stasis and producing the fresh blood. 3. Result 3. 1 Experimental Research 3. 1. 1 The effects of ITP model mice's general state and swimming time by the treatment of ZIDIANKELI After the fifth day of establishing the model, the model group appeared following symptoms: activity reduced, liking to gather together, piloerection, no sheen of the hair, swimming time reduction. To compare with the normal group, it is has statistical significance.
结果 3.1 实验研究 3.1.1 紫癜颗粒对ITP模型小鼠一般状况及游泳时间的影响模型组在注射APS48小时后,腹部、尾部出现轻重不等的瘀斑瘀点;造模后第5天小鼠即出现活动减少、拱背、竖毛、毛发不光洁,游泳时间显著缩短(P.05);紫癜颗粒对上述症状都有不同程度的改善作用,总体上以大剂量组效果最佳。
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There are more than 95% in the 34 patiens who have skin ecchymosis, petechia and epistaxis at different degrees. Females also suffere from menorrhagia. When their PT, APTT and FIB were norma and the possibility of DIC was excluded, 3 patients died of cerebral hemorrhage caused thrombocytopenia, accounting for 8.8% of the total death cases.
单纯血小板低引起出血与死亡的关系本组34例患者中95%的都有不同程度的皮肤瘀点,瘀斑、齿龈出血和鼻衄,女性患者可有月经过多,其中有3例患者在PT、APTT、FIB正常,排除DIC的情况下确诊为血小板低导致脑出血而死亡,占总死亡率的8.8%。
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AFP:甲胎蛋白
如肝区不适、疼痛、腹胀、食欲不振、恶心、呕吐、腹泻、发热、乏力、全身关节痛、鼻衄、牙龈出血、皮下瘀斑和越来越明显的消瘦等. 健康体检时常规检测"乙肝表面抗原"(澳抗)、"丙型肝炎病毒"(HCV)和"甲胎蛋白"(AFP),对早期发现肝炎病史和无症状的肝癌,有重要意义.
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lymphangiosarcoma:淋巴管肉瘤
8.淋巴管肉瘤(lymphangiosarcoma) 淋巴管肉瘤(lymphangiosarcoma)在小儿极为罕见,高度恶性,肿瘤呈现一个坚韧的肿块,如色青的瘀斑,高出皮面,相近的皮肤,皮下组织,肌肉有纤维化,肿瘤多发生于四肢,向近远端发展,对淋巴管肉瘤无有效治疗方案,
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Petechiae:瘀斑
智利的HPS有6例小于17岁的儿童,其中至少3例有瘀斑(petechiae),而所有成年病人均有显微血尿及管型,此与北美HPS病人无肾损及出血表现不同(与BCC及BAY病毒有关的少数病人伴有肾损症状).
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petechial:瘀点的, 瘀斑的 (形)
petechia 瘀斑; 瘀点 (名) | petechial 瘀点的, 瘀斑的 (形) | petechiate 有瘀点的, 有瘀斑的 (形)
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petechiate:有瘀点的, 有瘀斑的 (形)
petechial 瘀点的, 瘀斑的 (形) | petechiate 有瘀点的, 有瘀斑的 (形) | peter out 逐渐消失