星形胶质细胞

基本解释 (translations)

astrocyte

与星形胶质细胞相关的网络例句 [注：此内容来源于网络，仅供参考]

Results The hind limb function of the injured rats recovered at different degrees, the most extent recovery occurred during the time site 1~2 week, recovery continued from 2 to 3 week and, BBB was up to 12 at the end of the third week, but there was no significance recovery during 3~4 week. the astrocyte caudal to the injury plane began hyperplasy and hypertrophy; astrocyte in which GFAP in expression was positive the gray matter increased obviously from 3 days to 14 days after hemisection. The expression of MBP is same as that of GFAP.

结果 伤后后肢均有不同程度的恢复，1~2周时恢复幅度最大，2~3周时后肢运动功能继续恢复，3周时BBB评分最高达12分，3~4周运动功能无显著性恢复，损伤后1 d损伤远端3~6 mm处GFAP阳性星形胶质细胞开始增生肥大，3~4 d灰质中星形胶质细胞明显增多，2周时达到高峰，损伤近端3~6 mm处少突胶质细胞的增生反应过程与星形胶质细胞相似。

The GFAP is a specific marker of astrocyte, its expression is more higher in the activity astrocyte, and finally the GFAP become the main composition of scar formations. The S -100 is a kind of acidity, dissolubilites, low molecular quantity and calcium hydronium conjugated protein, and it is mainly existed in neuroglial cell and schwann cell. It can promote the growth of axon, glial hyper-plasia and nerve divide and calcium's stability inside of cell, thus regulatin g the shape and metabolism of astrocyte . The quantity of S -100 protein and the degree of ischemia have direct proportion .

胶质纤维酸性蛋白是星形胶质细胞的特异性标记物，在活性星形胶质细胞中GFAP的表达相对更高，且最后GFAP成为胶质疤痕的主要成份。S-100蛋白是一种酸性、可溶性、低分子量的钙离子结合蛋白，主要存在于胶质细胞和雪旺细胞中，它可促进轴突生长、胶质增生、神经分化和细胞内钙的稳定，从而调节星形胶质细胞的形态和代谢。S-100蛋白与缺血的程度是成正比的。

Results (1)Astrocytes and oligodendrocytes in mixed culture appeared better growth and differentiation than the respectively purified neuroglial, especially for the oligodendrocytes.(2) There were many pseudopod process among the astrocytes, which appeared centripetal growth mode.(3) The passaged astrocytes kept good abilities of division and proliferation and completely fused after 1 week of growth, and the purity was over 95%.

结果 (1)混合培养的星形胶质细胞和少突胶质细胞生长分化状况均优于纯化后的生长，以少突胶质细胞表现更为明显；(2)星形胶质细胞呈向心性生长，细胞相邻的接触面有较多的伪足；(3)传代培养的星形胶质细胞保持较强的分裂增殖能力，可在1周左右生长至完全融合，其纯度可达95%以上。

Objective: To observe the quantitative and morphological changes of astrocytes in nucleus of solitary tract after vagus nerve stimulation.

目的：观察颈部迷走神经千刺激后孤束核内星形胶质细胞数量、形态的改变，同时在电镜水平观察星形胶质细胞与神经元之间突触形态、数量的变化，从胶质细胞的角度阐明VNS治疗神经精神疾病的重要机制。

Astroglia had an apprant change of cell cycle in epileptogenesis, which may be an important mechanism involing gliosis and even development of glial scar.

星形胶质细胞细胞周期的改变是引起星形胶质细胞过度增殖，产生胶质疤痕和形成癫痫的重要机制之一。

Methods The NGF, BDNF, and NT3 genes of rats were cloned, the eukaryote expression vectors were established, the three kind of recombinant vectors were used to transfect astrocytes, the positive cloned cells were cultured dilatedly after G418 sifting; using supernates of culture liquid of astrocytes modified by gene to culture PC12 or TrkB-PC12, the expression and its level of gene target cells aimed genes were measured by Western blotting or immunohistochemical method.

克隆大鼠NGF、BDNF和NT3基因，构建真核表达载体；3种重组载体分别转染星形胶质细胞，G418筛选后获得阳性克隆细胞进行扩大培养；取基因修饰星形胶质细胞培养液上清培养PC12细胞或TrkB-PC12细胞；用Western blotting杂交或免疫组织化学方法检测基因靶细胞目的基因的表达及其水平。

Methods HE and immunohistochemistry were used to observe the changes of glial fibrillary acidic protein and CD34 in the surrounding areas after cerebral infarction in human.

方法采用HE染色观察星形胶质细胞和微血管的变化，免疫组化技术检测胶质纤维酸性蛋白和CD34在星形胶质细胞和微血管的表达。

After cocultured with reactive astrocytes, olfactory ensheathing cells can promote the proliferation of reactive astrocytes,and reduce the astrocyte gliosis and expression of inhibitory cytokines.

嗅鞘细胞作用于活化后的星形胶质细胞以后，能够促进星形胶质细胞的分裂增殖，同时能够减少星形胶质细胞胶质化，降低抑制性细胞因子的表达。

Results: ApoD was observed positively expressed in type2 astrocytes and oligodendrocytes from O2A lineage, while it was not expressed in type1 astrocytes from T1A lineage. Accordingly, we can verify the phenomenon found in the study of T1A and T2A gene different expression profile that ApoD mRNA was highly expressed in T2A and lowly expressed in T1A. Conclusion: It can be concluded that lipid metabolism related genes such as ApoD play important roles in the generation and differentiation of O2A lineage, which closely correlate with internal mechanism of lipid metabolism in the brain and myelogenesis.［Key words］astrocyte(T1A, T2A); oligodendrocyte; O2A lineage; apolipoproteinApoD

我们已采用基因芯片技术在mRNA水平研究两型星形胶质细胞的基因表达谱差异，发现ApoD在2型星形胶质细胞中差异高表达，故本文拟用激光共聚焦双重免疫荧光标记技术进一步在蛋白质水平观察ApoD在体外分化成熟的两型星形胶质细胞以及少突胶质细胞中的表达情况，以期为我们深入研究ApoD等脂代谢相关基因在脑内脂质代谢和神经髓鞘发育机制中所起的作用提供有用的实验依据，依此探讨胶质细胞发生和分化的信号机制。

Kangdai Ⅰ has protective function to the damaged neurons and astrocytes: Main results:(1) It has direct protective function to the damaged neurons. It can increase the activity and survival rate, decrease the mortality and the transudation rate of LDH in cultured medium and the strong positive cell count of NOS expression of injured neurons.(2) It has also directly protective function to the damaged astrocytes. It can increase the activity and survival rate and protein content in conditioned medium.(3) It can strengthen the ability of BDNF, GDNF, bFGF, HSP and IL-6expression in damaged astrocytes.(4) It can also strengthen obviously the expressions of NSE, bFGF-receptor and bc1-2, lower the expression of bax and caspase-3.(5) It can indirectly protect and restore the damaged neurons by astrocytes. Because the effect of ACMK (ACM interfered by Kangdai Ⅰ) is stronger than ACM+K (ACM associated with Kangdai Ⅰ).

抗呆Ⅰ号对受损的神经元和星形胶质细胞均具有保护作用：主要表现为：(1)对受损神经元具有直接的保护作用，可提高受损神经元的活性和存活率，降低细胞培养液LDH的漏出率、细胞死亡率和NOS染色强阳性细胞的表达量；(2)对受损的星形胶质细胞也有直接的保护作用，可提高其活性、存活率以及培养液蛋白质的含量；(3)能增强受损星形胶质细胞分泌BDNF、GDNF、bFGF、HSP和IL-6的能力；(4)可明显增强受损神经元对NSE、bFGF的受体和bc1-2的表达，降低受损神经元对bax和caspase-3的表达；(5)抗呆Ⅰ号可通过星形胶质细胞间接地保护和修复受损的神经元，因为在多数实验组中经抗呆Ⅰ号作用的ACM的作用远大于ACM与抗呆Ⅰ号联合应用的作用，统计学上具有显著性差异。

与星形胶质细胞相关的网络解释 [注：此内容来源于网络，仅供参考]

astrocyte：星形胶质细胞

1.星形胶质细胞 星形胶质细胞(astrocyte)是胶质细胞中体积最大的一种,与少突胶质细胞合称为大胶质细胞(macroglia). 细胞呈星形,核圆形或卵圆形,较大,染色较浅. 星形胶质细胞可分两种:①纤维性星形胶质细胞(fibrous astrocyte),

protoplasmic astrocyte：原浆性星形胶质细胞

②原浆性星形胶质细胞(protoplasmic astrocyte),多分布在灰质,细胞的突起较短粗,分支较多,胞质内胶质丝较少. 星形胶质细胞的突起伸展充填在神经元胞体及其突起之间,起支持和分神经元的作用. 有些突起末端形成脚板(end feet),附在毛细血管壁上,

fibrous astrocyte：纤维性星形胶质细胞

根据胶质丝的含量以及胞突的形状可将星形胶质细胞分为两种:纤维性星形胶质细胞(fibrous astrocyte)多分布在脑脊髓的皮质,突起细长,分支较少,胞质中含大量胶质丝,又称蜘蛛细胞(spider cell);原浆性星形胶质细胞(protoplasmic astrocyte),

mixed astrocyte：混合型星形胶质细胞

mixed astigmatism 混合散光,混合性散光 | mixed astrocyte 混合型星形胶质细胞 | mixed avalanche 混合崩坍

Astrocyte Medium：(星形胶质细胞培养基)

Astrocyte Medium(星形胶质细胞培养基) | Human peridontal ligmant firbroblast cDNA(人齿根膜韧带纤维原细胞) | Human esophageal smooth muscle cell cDNA(人食管平滑肌细胞)

astrocytoma：星形胶质细胞瘤

胶质瘤(glioma)具有特异的不同于其它部位肿瘤的生物学特性:1.星形胶质细胞瘤(astrocytoma) 本瘤约占颅内肿瘤的30%,占神经胶质瘤的70%以上. 男性较多见. 最近研究表明该肿瘤中原癌基因sis有过度表达,erb-B1则有放大.

astroblast：成星形胶质细胞

成胶质细胞首先分化为各类胶质细胞的前体细胞,即成星形胶质细胞(astroblast)和成少突胶质细胞(oligodendroblast). 然后,成星形胶质细胞分化为原浆性和纤维性星形胶质细胞,成少突胶质细胞分化为少突胶质细胞. 最近有人在体外培养的研究中发现,

astroglia cell：星形胶质细胞

astrocytoma 星形细胞瘤 | astroglia cell 星形胶质细胞 | asymmetrical synapse 不对称型突触

fibrous astroglia cell：纤维性星形胶质细胞

fibrosis 纤维化 | fibrous astroglia cell 纤维性星形胶质细胞 | filium terminale 终丝(脊髓)

ganglioneuroma：节细胞神经瘤 神经节瘤 星形胶质细胞瘤

ganglioneurofibromaofmediastinum 纵隔节细胞性神经纤维瘤 | ganglioneuroma 节细胞神经瘤 神经节瘤 星形胶质细胞瘤 | gangliongeniculi 膝神经节