- 更多网络例句与微粒体相关的网络例句 [注:此内容来源于网络,仅供参考]
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On the other hand, the hepatic microsomal aminopyrine demethylase activity was obviously inhibited 2 hours after administration of the same dose of SY-801 and SY-640, while the content of hepatic cytochrome P-450 was not affected.
体外实验表明,SY-801和SY-640对正常小鼠、3-甲基胆蒽(3-MC)处理小鼠及苯巴比妥处理小鼠小鼠肝微粒体氨基比林脱甲基酶活性都具有明显的抑制作用,其中对3-MC处理小鼠肝微粒体氨基比林脱甲基酶活性抑制作用最显著。
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The above results suggests that the hydrolase and FMO in microsomes are involved in the formation of M1 and M2 respectively.
黄素单氧化酶的特异性抑制剂甲巯咪唑可以显著地抑制M2的形成,但对M1的形成无明显的抑制作用,且M1在肝微粒体中的形成为NADPH非依赖性,上述结果提示参与M1和M2代谢的酶分别为肝微粒体中的水解酶和黄素单氧化酶。
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The weight and protein content of the microsomes from different evolutionary animal and tissue cells were first determined, and the weight of microsome varies obviously and the protein content of microsome in unit is almost the same.
本文还首次系统比较了不同组织细胞和不同进化程度动物细胞的微粒体获得率及蛋白含量,得到了不同细胞微粒体获得率明显不同、单位重量微粒体蛋白含量却基本相同的结果,表明不同细胞ER含量不同,而单位ER内蛋白含量基本相同。
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Methods: Liver microsome was preparated from normal rat and human liver, which was to he treated with a series of concentrations of CsA or coadministration with Flu or MP. The activities of CYP3A in the microsomes were detected by using erythromycin as substrate.
製备大鼠和人肝微粒体,用不同浓度的CsA作用、加或不加MP、Flu,以红霉素为底物,经过NADPH系统孵育后,利用分光光度法测定人和大鼠肝微粒体的红霉素N-脱甲基酶活性。
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We employed HPLC to measure the metabolites of caffeine in the whole blood and calculated the ratio be between the metabolite and caffeine, which was used as index to evaluate the effect of Qingkailing injection on rat CYP1A2 activity in vivo ; We also detected the CYP1A2 and CYP2D6 activity in microsomal reconstituted system by analysis of phenacetin metabolism and dextromethorphan metabolism with HPLC.
通过HPLC法测定全血中咖啡因的代谢率,观测清开灵注射液对大鼠CYP1A2活性的影响;通过HPLC法测定大鼠肝微粒体重组系统非那西丁的代谢比率,确定清开灵注射液对大鼠肝微粒体CYP1A2亚型的作用;测定大鼠肝微粒体重组系统右美沙芬的代谢比率,确定清开灵注射液对大鼠肝微粒体CYP2D6亚型的作用。
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In addition, the dose-response experiment of hepatic EROD in porgy induced by 0# disel oil WAF was studied to dsicuss the possibility to use it as a biomarker for monitoring environmental pollution.
另外,也初步开展了黄鳍鲷肝微粒体EROD的剂量—效应研究,探讨了这种鱼肝微粒体EROD酶作为污染监测指标的可能性。
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Furthermore, taurine-treated microsomes showed a higher incorporation of radiolabled oleoyl-CoA into diacylglycerol, phosphatidylethanolamine, sphingomyelin and lysophosphatidylcholine lipid fraction in comparison with the control microsomes.
牛磺酸可改变微粒体膜脂质成分(如降低游离胆固醇、磷脂酰丝氨酸和鞘磷酸,升高磷脂酰乙醇胺和磷脂酸的浓度)和膜磷脂脂肪酸成份,并降低微粒体膜脂质的流动性。
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Methods Beagle dog liver microsomes were prepared by using ultracentrifuge method. After incubating 0.4 μmolL^(-1) MN9202 with 1 gL^(-1) microsomes for 30 min at 37℃, the reaction was terminated by adding 0.5 mL alkalization. The RP-HPLC was used to determine the drug in the incubation mixture.
差速离心法制备Beagle犬肝微粒体酶,0.4μmolL^(-1)的MN9202与1.0gL^(-1)的肝微粒体酶在37℃水浴中孵育30min,加入0.5mL碱化液终止反应,然后采用RP-HPLC法测定孵育液中MN9202原形药物的浓度。
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At concentration of 2% PEG8000, 30% microsomal protein containing 10% of total P450 was precipitated. At concentration of 5% PEG8000, 55% microsomal protein containing 20% of total P450 was precipitated. At concentration of 8% PEG8000, 78% microsomal protein containing 30% of total P450 was precipitated. At concentration of 11% PEG8000, 85% microsomal protein containing 70% of total P450 was precipitated.
当PEG的浓度为2%时,约30%的微粒体蛋白和10%的P450被沉淀;PEG为5%时,约55%的微粒体蛋白和20%的P450被沉淀;PEG为8%时,约78%的微粒体蛋白和30%的P450被沉淀;PEG为11%时,约85%的微粒体蛋白和70%的P450被沉淀。
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The technique of liver CYP450 enzymes was applied to the in vitro study of drug metabolism In the first part of this article, the metabolism of nimodipine in human liver microsomes was studied and in the second of part of this article the metabolism of clivorine in female rat, guinea pig, human liver microsomes as well as the mechanism of metabolism-induced toxicity were investigated.
运用肝微粒体技术进行药物的体外代谢研究。本论文第一部分运用肝微粒体技术研究了尼莫地平在人肝微粒体内的代谢及其代谢的酶动力学,第二部分研究了肝毒性生物碱Clivorine在大鼠、豚鼠和人肝微粒体内的代谢及其代谢致毒机理。
- 更多网络解释与微粒体相关的网络解释 [注:此内容来源于网络,仅供参考]
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microsome:微粒体
╬※ 微粒体(microsome)是在细胞匀浆和超速离心过程中,由破碎的内质网形成的近似球形的囊泡结构,含有内质网与核糖体两种成分,它仍然具有蛋白质合成蛋白糖基化、脂类合成等功能.
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microsome:微粒體(原漿微粒) 微粒体
microscopical identification 顯微鑒別 显微鉴别法 | microsome 微粒體(原漿微粒) 微粒体 | microsphere 微球 微球
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pancreatic microsome:胰微粒体
pancreatic juice 胰液 | pancreatic microsome 胰微粒体 | pancreatic ribonuclease 胰液核糖核酸酶
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hepatic microsome:肝微粒体
肝脏肿瘤:Hepatic neoplasm | 肝微粒体:hepatic microsome | 肝损伤:acute hepatic injury
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microsome fraction:微粒体部分
microsome activation method 微粒体活化法 | microsome fraction 微粒体部分 | microsound scope 小型测振仪
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microsomal enzyme:微粒体酶
microscopical preparation 显微镜制片 | microsomal enzyme 微粒体酶 | microsome 微粒体
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microsomal enzyme:微粒体酶类
microsequencing 微量测序 | microsomal enzyme 微粒体酶类 | microsome 微粒体
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microsomal enzyme:微粒体 類
microsequencing 微量測序 | microsomal enzyme 微粒体 類 | microsome 微粒体
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microsomal antibody:微粒体抗体
microsome 微粒体 | microsomal antibody 微粒体抗体 | microsecond 微秒
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microsomal enzymes:微粒体酶类
microsequencing 微量测序 | microsomal enzymes 微粒体酶类 | microsome 微粒体