形成纤维性组织

基本解释 (translations)

fibrose

与形成纤维性组织相关的网络例句 [注：此内容来源于网络，仅供参考]

To investigate the expression of cyclooxygenase-2(COX-2) in carcinogenesis lesions of oral submucous fibrosis, and the effects of arecoline on the expression of COX-2 in cultured human oral keratinocytes.

目的 探讨环氧合酶－2(COX-2)在口腔黏膜下纤维性变癌变组织中的表达，观察槟榔碱对人口腔角质形成细胞COX-2表达的影响。

All 7 cases were characterized by deposition of dystrophic or psammatous calcifications accompanied with chronic inflammatory cells infiltration in the stroma. In some cases, there was formation of germinal centers.

特徵性形态学表现为在胶原化的纤维组织间可见散在的钙化灶或砂砾小体，间质内伴有多少不等的淋巴细胞和浆细胞浸润灶，部分病例中可见生发中心形成。

ResultsMacroscopic examination showed no excrescence,thrombus formation,arm fractures and corrosion.The devices were covered with collagen fibrosis and discrete endocardial cells,apparent inflammatory infiltration in the devices and around the devices 1 month after implantation.The implants were nearly endothelialized,while the inflammatory reaction relieved gradually,with myocardial cells ingrowth at the edges of the device 3 months after implantation.The devices were completely covered with endocardium and fibrous tissue.Moreover,endothelial cells could be found on the smooth microscrew adaptor.The inflammatory reaction diminished with a few chronic inflammatory cells existing.Neovascularization and lymphatic vessels ingrowth could be observed 6 months after implantation.

结果所有封堵装置表面均没有发现赘生物、血栓形成、支架发生断裂及被腐蚀；术后1个月，封堵装置表面被胶原纤维和散在内皮细胞所覆盖，大量炎症细胞浸润，封堵装置边缘有小灶性炎症细胞浸润；术后3个月，封堵装置表面几乎被内皮细胞所覆盖，炎症细胞较1个月时明显减少，封堵装置内见纤维化，封堵装置边缘心肌细胞浸入；术后6个月，封堵装置表面完全被心内膜和纤维组织所覆盖，伞尖表面光滑并有内皮细胞上爬，炎症反应明显消散，但仍有少量慢性炎症细胞存在，装置内有新生的血管、淋巴管长入。

The stable clones are further identified by RT-PCR and Western blot; 6 MTT assay is used to investigate the effect of ZNRD1 on the cell growth of cells (AGS, SGC7901, MKN28, NIH3T3, GES-1); 7 Soft agar assay is used to investigate the effect of ZNRD1 on the clonality of cells (AGS, MKN28); 8 Nude mice assay is used to investigate the effect of ZNRD1 on the cell growth of gastric cancer cells (AGS, MKN28); 9 Flow cytometry is used to investigate the effect of ZNRD1 on the cell cycle distribution of cells (AGS, MKN28, NIH3T3, GES-1); 10 Flow cytometry is used to investigate the effect of ZNRD1 on the cell apoptosis of cells (AGS, MKN28, NIH3T3); 11 MTT assay is used to investigate the effect of ZNRD1 on the drug sensitivity of cancer cells (SGC7901, SGC7901/VCR, HL-60, HL-60/VCR) in vitro; 12 SRCA is used to investigate the effect of ZNRD1 on the drug sensitivity of gastric cancer cells (SGC7901, SGC7901/VCR) in vivo; 13 Flow cytometry is used to investigate the effect of ZNRD1 on adriamycin accumulation of cancer cells (SGC7901, SGC7901/VCR, HL-60, HL-60/VCR); 14 Transmission electron microscope is used to investigate the effect of ZNRD1 on the sensitivity of SGC7901 cells towards drug-induced apoptosis; 15 Flow cytometry and DNA ladder assay are used to investigate the effect of ZNRD1 on the sensitivity of cells (SGC7901, SGC7901/VCR, HL-60/VCR) towards drug-induced apoptosis; 16 Microarray is used to investigate the profiling of ZNRD1-responsive genes in gastric cancer cells (AGS, MKN28, SGC7901, SGC7901/VCR); 17 RT-PCR and Western blot are used to identify the results of microarray; 18 Reporter gene assay is used to investigate the effect of ZNRD1 on the transcriptional activity of cyclin D1; 19 Reporter gene assay is used to investigate the effect of ZNRD1 on the transcriptional activity of MDR1; 20 Kinase assay is used to investigate the effect of ZNRD1 on the activity of cyclin E-CDK2 kinase; 21 The antisensenucleic acids of p21 is used to inhibit the expression of p21, and flow cytometry is used to investigate the effect of p21 on ZNRD1-induced cell cycle arrest in gastric cancer cells; 22 The antisensenucleic acids of p27 is used to inhibit the expression of p27, and flow cytometry is used to investigate the effect of p27 on ZNRD1-induced cell cycle arrest in gastric cancer cells; 23 Liposome is used to up-regulate the expression of Skp2, and flow cytometry is used to investigate the effect of Skp2 on ZNRD1-induced cell cycle arrest in gastric cancer cells; 24 Western blot is used to investigate the effect of ZNRD1 on the stability of Skp2 and p27 in gastric cancer cells; 25 MVD assay is used to investigate the effect of ZNRD1 on the angiopoietic activity of gastric cancer cells; 26 ELISA is used to investigate the effect of ZNRD1 on the expression of VEGF165 in gastric cancer cells; 27 The roles of DARPP-32 in MDR of gastric cancer cells are investigated using gene transfection, MTT assay, SRCA, flow cytometry and DNA ladder assay.

应用杂交瘤技术制备ZNRD1的首个单克隆抗体；2）利用RT-PCR、Western blot和免疫组化检测ZNRD1在胃癌组织、胃炎组织、正常胃上皮组织、胃癌细胞和正常胃组织上皮细胞中的表达；3）构建ZNRD1的小干扰RNA载体，并测序鉴定；4）利用脂质体将ZNRD1的真核表达载体及其空载体转染胃癌细胞（AGS、SGC7901、MKN28）和小鼠成纤维细胞（NIH3T3），G418筛选后进行鉴定；5）利用脂质体将ZNRD1的小干扰RNA载体及其空载体转染药敏胃癌细胞（SGC7901）、正常胃组织上皮细胞（GES-1）、对长春新碱耐药的胃癌细胞（SGC7901/VCR）、药敏白血病细胞（HL-60）、对长春新碱耐药的白血病细胞（HL-60/VCR），G418筛选后进行鉴定；6）利用MTT实验检测ZNRD1高/低表达对细胞（AGS、SGC7901、MKN28、NIH3T3、GES-1）生长的影响；7）通过软琼脂克隆形成实验检测上调ZNRD1对AGS、MKN28细胞克隆形成能力的影响；8）通过裸鼠成瘤实验检测上调ZNRD1对AGS、MKN28细胞体内成瘤性的影响；9）通过流式细胞仪分析ZNRD1高/低表达对细胞（AGS、MKN28、NIH3T3、GES-1）的细胞周期的影响；10）通过流式细胞仪分析上调ZNRD1对细胞（AGS、MKN28、NIH3T3）的凋亡的影响；11）通过MTT实验检测ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR、HL-60、HL-60/VCR）体外药物敏感性的影响；12）通过肾包膜下移植法检测ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR）体内药物敏感性的影响；13）通过流式细胞仪分析ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR、HL-60、HL-60/VCR）内阿霉素蓄积和泵出的影响；14）通过透射电镜检测上调ZNRD1对SGC7901细胞凋亡敏感性的影响；15）通过流式细胞仪和DNA梯度试验检测ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR、HL-60）凋亡敏感性的影响；16）通过基因芯片检测ZNRD1高/低表达对胃癌细胞内基因表达谱的影响；17）利用RT-PCR、Western blot对基因芯片的结果进行鉴定；18）利用报告基因实验检测ZNRD1对cyclin D1的启动子活性的调节作用；19）利用报告基因实验检测ZNRD1高/低表达对MDR1的启动子活性的调节作用；20）利用激酶试验检测ZNRD1对cyclin E-CDK2 激酶活力的影响；21）利用反义核酸技术抑制p21的表达；通过流式细胞仪检测抑制p21对ZNRD1介导的细胞周期阻滞的影响；22）利用反义核酸技术抑制p27的表达；通过流式细胞仪检测抑制p27对ZNRD1介导的细胞周期阻滞的影响；23）利用脂质体转染法上调Skp2的表达；通过流式细胞仪检测上调Skp2对ZNRD1介导的细胞周期阻滞的影响；24）利用Western blot检测ZNRD1对p27和Skp2的蛋白稳定性的影响；25）利用微血管密度实验检测ZNRD1对AGS、MKN28细胞裸鼠移植瘤微血管形成的影响；26）利用ELISA检测ZNRD1对AGS、MKN28细胞培养上清和移植瘤匀浆中VEGF165含量的影响；27）利用脂质体转染法、MTT实验、肾包膜下移植法、流式细胞仪和DNA梯度试验检测新耐药相关分子DARPP-32对细胞（SGC7901、SGC7901/VCR、对阿霉素耐药的胃癌细胞SGC7901/ADR）多药耐药表型的影响；利用脂质体转染法和MTT实验检测下调ZNRD1对DARPP-32介导的胃癌多药耐药的调控作用。

The inflammation reaction hyperplactic stage and lymphatic nodular stage are of nonspecific morphological changes and should be diagnosed with the help of positive tuberculin test and obvious increase of adenosine deaninase ; tuberculous nodular stage has a great number of epithelioid cells,and Langhans cells, caseous necrosis stage is characterized by a great deal of necrotic tissue and debris,a small number of fragmented epithelioid cells, and mainly by antiacid bacteria fibrinous hyperplastic stage is featured by a few fibrous tissue, cells and mucous oweing to hardness to get puncture, neans tuberculous restoration,and scar formation.

结核初期-炎性增殖期60例，占5.5%；结核早期-淋巴结节期130例，占11.9%；结核中期-结核性结节期有590例，占54.1%；结核晚期-干酪样脓样坏死期有280例，占25.7%；结核恢复期-纤维素增殖期30例，占2.8%。炎性增殖反应期非特异性形态学变化，需要结合结核抗体阳性和腺苷酸脱氨酶明显增高有助于诊断，结核结节期主要可有较多类上皮样细胞及郎罕氏细胞；而干酪样脓样坏死主要见大量坏死组织及碎屑、少数残碎不全类上皮样细胞，此期主要能查到抗酸菌为特点；纤维增殖期，抽出物难取，仅见少数纤维组织、纤维细胞和黏液间质为其特征，提示结核恢复、瘢痕形成所致。

Microscopically, this bile duct in a case of sclerosing cholangitis is surrounded by marked collagenous connective tissue deposition.

显微镜下可见硬化性胆管炎的胆管被大量的纤维组织包绕而形成了胆管阻塞。

What was observed under a light microscope included: tumor cells were mulberry and micropapillary shaped or were of glandule tubular arrangement; there was obvious interspace between cancer nest and neighboring areas; micropapillary was empty of fiber blood vessel axes, with micropapillae floating freely in spongy spaces and separated by fibrous septa.

光镜下特征性表现为肿瘤细胞呈桑椹状、微乳头状或小腺管样排列，癌巢与周围间质形成明显的空隙，微乳头缺乏纤维血管轴心，每个微乳头细胞团和周边的纤维组织均存在无细胞的间隙样结构；瘤细胞CerbB-2、CgA和EMA。

Swyer-James syndrome is considered to be a post-infectious form of bronchiolitis obliterans, pathologically defined by the presence of submucosal and peribronchiolar fibrosis with destruction and obliterative scarring of the small airways.

Swyer-James综合征被认为是闭塞性细支气管炎感染后形成的，病理表现为出现黏膜下及支气管周围纤维化并有小气道破坏和疤痕组织，SJS是一类有不同临床表现的综合征，这些表现主要与囊状支气管扩张是否出现有关。

与形成纤维性组织相关的网络解释 [注：此内容来源于网络，仅供参考]

contraction：挛缩

挛缩(contraction):挛缩是大的伤口内组织丢失的过程. 而且正常组织内迁移减少. 从成纤维细胞转变的肌纤维细胞,具有平滑肌细胞及成纤维细胞两种的特性. 其表现为形成粘结(由于有肌动球蛋白)并挛缩,肌纤维中发现有收缩性的蛋白.

exfoliation：剥落

相较於在蜕膜形成纤维性的疤痕,胎盘部位的愈合是一种剥落(exfoliation)的过程. 胎盘部位是在成长的子宫内膜组织之下,来自於此部位的边缘及基底层中子宫内膜腺体的基底. 此梗塞的表面组织随后会变得坏死并脱落. 剥落是复旧中最重要的部分之一.

granulation tissue：肉芽组织

肉芽组织(granulation tissue)乃由旺盛增生的毛细血管及纤维结缔组织和各种炎性细胞组成,肉眼表现为鲜红色,颗粒状,柔软湿润,形似鲜嫩的肉芽故名. 镜下可见大量由内皮细胞增生形成的实性细胞索及扩张的毛细血管,向创面垂直生长,并以小动脉为轴心,

inflammation：发炎

由纤维结缔组织以及肉芽组织所构成,水瘤开始时,因为压力而损害到骨上方软组织的循环,假如压力持续,局部性的缺血发展,就导致细胞坏死以及水肿,因为周围的组织也被涉及,所以液体无法被吸收,发炎(Inflammation)变剧烈时,一个纤维性囊形成,

suberin：木栓质

病原菌侵染和伤害都能诱导木栓质(suberin)在细胞壁微原纤维间积累,木栓化常伴随植物细胞重新分裂和保护组织形成,以替代已受到损害的角质层和栓化层周皮等原有的透性屏障.

collagenic fiber：胶原纤维

即管平衡听泡形成后其四周的间质组织 (mesenchymal tissue) 即变成听囊迷路,其与膜性迷路之间形成外淋巴间隙(perilymphatic space) 并蜗部分的外淋巴间隙分成二个部分,即鼓阶(scala tympani)及前庭成,其中间的胶原纤维(collagenic fiber)则为第一第二鳃弓的

desmoid tumor：韧带状瘤

<正> 本病又称韧带状瘤(desmoid tumor)或侵袭性纤维瘤病(aggressive fibromatosis),是介于良恶性之间的纤维性肿瘤. 其特点为纤维组织的增生并形成瘤样病变,增生的纤维组织较为成熟,与纤维瘤相似,但无包膜. 病变源自肌筋膜,常呈浸润性生长,

granulomatous inflammation：肉芽肿性炎

亦可合并存在.四,增生性炎 (一)一般性增生性炎:基本病理变化 增生:成纤维细胞,小血管,实质细胞 以单核淋巴细胞为主的慢性炎细胞浸润,组织坏死和组织修复同时存在 (二)肉芽肿性炎(granulomatous inflammation) :以肉芽肿形成为其特点,

pannus：关节翳

B )同一关节上,形式关节翳( Pannus )软骨受破坏,并且严重发炎C )发炎渐渐减退而形成纤维性关节黏连 (fibrous ankylosis )D )最后转变成骨质关节黏连( bony ankylosis )有不少名词形容骨骼组织上的疼痛,

Bandaging：(绷带)

局部性的缺血发展,就导致细胞坏死以及水肿,因为周围的组织也被涉及,所以液体无法被吸收,发炎(Inflammation)变剧烈时,一个纤维性囊形成,与周围区域区隔.6.传统疗法是抽取液体(Aspiration),然后绑绷带(Bandaging)的方法,可以尝试看看,