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To further study the chemical constitutes of lipophilic active parts, we prepared Alc95% and Alc50% according to original literature. 20 compounds were isolated by using macroporous resin, silica gel, polyamide, Sephadex LH-20, Rp-18, preparative TLC and preparative HPLC chromato-graphy. The structures of them were elucidated by means of physical and chemical properties, modern spectroscopic analysis techniques—UV、IR、 EI/MS、ESI/MS、〓H-NMR、〓C-NMR、DEPT、HMQC、HMBC. They are nine anthraquinones: chrysophanol (95-1), physcion (95-2), emodin (95-5), aloemodin (95-7), rhein (50-1), sennoside A or B (50-6),ω-hydroxylemodin (95-10), chrysophanol-8-0-β-D-glucoside (95-12), aloemodin-ω-0-β-D-glucoside (95-13); three phenanthaquinones: tanshinone ⅡA (95-3), cryptotanshinone (95-6), tanshinone Ⅰ(95-4); one isoflavone: 7, 3'-dihydroxyl-5' methoxyisoflavone (95-14) and protocaechuic aldehyde (95-9), protocaechuic acid (95-11), astragaloside Ⅳ(50-4), amygdalin (50-5), 2, 3, 5, 4'-tetrahydroxylstilbene-2-0-β-D-glucoside (50-3),-catechin (50-2), cinnamic acid (95-8). Among them, 3'-dihydroxyl-5' methoxyisoflavone (95-14) is a new compound.
经过溶剂萃取、大孔吸附树脂富集、Sephadex LH-20精制、制备TLC及Semi-pre HPLC等手段从中分离了20个化合物,利用理化性质和波谱技术(UV、IR、EI/MS、ESI/MS、〓H-NMR、〓C-NMR、DEPT、HMQC、HMBC)相结合鉴定了它们的结构,分别为9种蒽醌类化合物:大黄酚,大黄素甲醚,大黄素,芦荟大黄素,大黄酸,番泻苷A或B,ω-羟基大黄素(ω-hydroxylemodin),大黄酚-8-0-β-D-葡萄糖苷(chrysophanol-8-0-β-D-glucoside),芦荟大黄素-ω-0-β-D-葡萄糖苷(aloemodin-ω-0-β-D-glucoside);3种菲醌类化合物:丹参酮ⅡA(tanshinoneⅡA),隐丹参酮,丹参酮Ⅰ(tanshinone Ⅰ);1种异黄酮:7,3'-二羟基-5'-甲氧基异黄酮(7,3'-dihydroxy-5' methoxyisofla-vone)以及原儿茶醛,原儿茶酸,黄芪甲苷(astragaloside Ⅳ),苦杏仁苷,2,3,5,4'-四羟基二苯乙烯-2-0-β-D-葡萄糖苷(2,3,5,4'-tetrahydroxylstilbene-2-O-β-D-g1ucoside),Z—儿茶素,桂皮酸。
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My company's main products: Rhynchophylline Gouteng silymarin (ethanol extract And no residual acetone) silymarin (water-soluble) silybin resveratrol daidzein emodin Suanzaoren extract of soy isoflavones curcumin, artesunate - Song Shupi extract, Hypericum perforatum extract, wild chrysanthemum extract, camptothecin, hawthorn extract, ursolic acid, corn required to extract, Maidong extract, garlic extract, ginsenosides, Chinese wolfberry extract - And asked Jing extract, green tea extract, the extract of small BAI Ju, Kushen extract, valerian extract, Salicylaldehyde glycosides, podophyllotoxin, Monascus Abulimiti of admission, puerarin extract, extract of astragalus, bitter melon extract Of, the thorn Tribulus terrestris extract, the extract of Ginkgo biloba leaves, Zhishi extract, Icariin, grape seed extract, Salvia extract yam extract, blueberry extract, the extract of Andrographolide, white Liu admission of Piti , Filed on Schisandra, Gynostemma extract, the extract of Angelica, Trifolium pratense extract, the extract of Rhodiola, soil Fritillaria saponins, Huang Chunju extract, and Cimicifuga extract, Hypericum perforatum Extract, Polygonum cuspidatum glycosides, genistein, reserpine, synephrine, sinomenine, Ciwujia glycosides, yam saponin, puerarin, peeling hormones, Kawa Ti of admission, lutein, lycopene, pumpkin seeds extract, licorice extract, nettle extract, the extract baicalin, Osthol, Asarum, saw Mr Brown extract, water Zaojiao extract, rutin extract, purple cabbage extract , Motherwort extract, Yanhusuo extract, hops extract, the extract of Magnolia officinalis, Cyclovirobuxine wood extract, Ban Langen extract, ginger extract, dandelion extract, senna extract, aloe extract , Dangshen extract, the extract of honeysuckle, quercetin, etc.
我公司主营产品:钩藤 Gouteng ·水飞蓟素·水飞蓟素·水飞蓟宾·白藜芦醇·大豆甙元·大黄素·大豆异黄酮·酸枣仁提取物·姜黄素,青蒿素松树皮提取物,连翘提取物,野菊花提取物,喜树碱,山楂提取物,熊果酸,玉米须提取物,麦冬提取物,大蒜提取物,人参总皂甙,枸杞提取物,问荆提取物,绿茶提取物,小白菊提取物,苦参提取物,缬草提取物,水杨甙,鬼臼毒素,红曲米提取物,葛根提取物,黄芪提取物,苦瓜提取物,刺蒺藜提取物,银杏叶提取物,枳实提取物,淫羊藿甙,葡萄籽提取物,丹参提取物,山药提取物,越橘提取物,穿心莲提取物,白柳皮提取物,五味子提起物,绞股蓝提取物,当归提取物,红车轴草提取物,红景天提取物,土贝母总皂甙,黄春菊提取物,黑升麻提取物,贯叶连翘提取物,虎杖甙,染料木素,利血平,辛弗林,青藤碱,刺五加甙,薯蓣皂素,葛根素,脱皮激素,卡瓦提取物,叶黄素,番茄红素,南瓜籽提取物,甘草提取物,荨麻提取物,黄芩提取物,蛇床子,细辛,锯叶棕提取物,水皂角提取物,芦丁提取物,紫甘蓝提取物,益母草提取物,延胡索提取物,啤酒花提取物,厚朴提取物,黄杨木提取物,板兰根提取物,生姜提取物,蒲公英提取物,番泻叶提取物,芦荟提取物,党参提取物,金银花提取物,槲皮素,等等
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Aloin and Isobarbaloin are major activity for anthraquinone derivative in Aloe. It's hydrolysis to aloe-emodin-9-anthrone, and oxidant to aloe-emodin at intestine bacteria.
芦荟大黄苷及异芦荟大黄苷是芦荟之蒽醌类衍生物的主要有效成分,经肠内细菌作用,水解成芦荟大黄素-9-蒽酮,再氧化成芦荟大黄素,而产生泻下作用。
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aloin:芦荟素
低分子类 芦荟素(aloin) 健胃、缓泻 异芦荟素(homonataloin) 健胃、缓泻 芦荟大黄素(aloemodin) 缓泻 芦荟乌尔辛(aloeulcin) 抗溃疡 芦荟酊(aloecin) 抗菌、抗病毒、中和毒素 芦荟辛(aloesin) 抗菌、解毒、激活细胞 芦荟宁(alodnin) 健胃 芦荟米嗪(aloemicin) 抗肿瘤 芦荟甙类(saponin) 泻下、排毒、消炎、抗菌、利尿 芦荟
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anthranol:蒽酚
芦荟泻素蒽酚或芦荟泻素蒽酮,芦荟大黄素甙的异构体异芦荟大黄素甙(Isobarbaloin),高塔尔芦荟素(Homonataloin),大黄酚(Chrysophanol),大黄酚葡萄糖甙(Chrysophanolglucoside),蒽酚(Anthranol)等蒽类及其甙类,以及榭皮素(Quercetin),