- 更多网络例句与异体的体外性的相关的网络例句 [注:此内容来源于网络,仅供参考]
-
METHODS: From January 2000 to May 2002, 52 cases with various types of bone defect were treated with tissue engineered bone, which was constructed in vitro by allogeneous osteoblasts from periosteum 1 x 10(6/ml with bio-derived bone scaffold following 3 to 7 days co-culture. Among them, there were 7 cases of bone cyst, 22 cases of non-union or malunion of old fracture, 15 cases of fresh comminuted fracture of bone defect, 4 cases of spinal fracture and posterior route spinal fusion, 3 cases of bone implant of alveolar bone, 1 case of fusion of tarsotarsal joint.
2000年1月~ 2002年1月,用同种异体骨膜来源的成骨细胞 1×106 / ml与生物衍生骨支架材料构建的组织工程骨,经体外培养 3~ 7天后,植入修复52例各种类型的骨缺损,其中骨囊性病变7例,陈旧性骨折不愈合或畸形愈合 2 2例,新鲜粉碎性骨折伴骨缺损 15例,脊柱骨折后路植骨融合术4例,牙槽骨植骨 3例,足跗中关节植骨融合 1例。
-
Construct PLXRN-IL-1Ra and PLXRN-IL-10 vector, lapine synoviocytes were first transduced in culture by retroviral infection. The genetically modified synovial cells were then transplanted by intra-articular injection into the knee joints, assay of joint lavages confirmed that the gene expression was not lost after 14 days of transfer. Knees receiving the hIL-1Ra had significantly reduced cartilage breakdown. Delivery of the hIL-10 was less effective, When both genes were used together, there was a greater inhibition of cartilage breakdown and a considerable reduction of cartilage matrix degradation.
构建PLXRN-IL-1Ra、PLXRN-IL-10逆转录病毒载体,体外感染同种异体原代滑膜细胞,接着将转染了外源基因的滑膜细胞行关节腔注射入创伤性骨关节炎兔膝关节,通过对关节滑液的ELISA分析证明外源基因的表达在基因转移后14天还很稳定,只接受hIL-1Ra基因治疗的膝关节软骨损坏明显减轻,接受hIL-10基因治疗的膝关节治疗也有一定效果,当两种基因同时导入时,有非常明显的抑制软骨破坏和软骨基质降解的作用。