小管间的

基本解释 (translations)

intercanalicular

与小管间的相关的网络例句 [注：此内容来源于网络，仅供参考]

Between P14 and P21,CIAPIN1 immunoreaction in the brain,heart and liverbecame much lower. However,between P21 and P28,CIAPIN1 immunoreactionin the heart,brain,liver and skeletal muscle became much lower,while with thekidney development,CIAPIN1 immunoreaction in the kidney became higher. Invarious tissues from adult mouse,CIAPIN1 immunoreaction could be seen incardiac muscle cell,brain,hepatocyte,epithelium of renal tubule,skeletal muscle,lung tissue,gastric mucosa and gland,acinus lienalis.2. Distribution of CIAPIN1 in normal fetal and adult human tissuesTo reveal the possible physiological role of CIAPIN1,we examined theexpression and distribution of CIAPIN1 in fetal and adult human tissues usingimmunohistochemistry. We found that CIAPIN1 was ubiquitously distributed infetal and adult tissues,and was localized in both the cytoplasm and the nucleus.

然而，在3个月大的成年鼠中，CIAPIN1阳性反应物在心、脑、肝和肾小管中的表达强度要低于P28小鼠；但CIAPIN1阳性反应物在成年鼠骨骼肌中较P28小鼠高。2、CIAPIN1蛋白在人5个月胚胎及成人多器官组织内的表达在人5月胚胎多器官组织中，CIAPIN1阳性反应物见于心脏、胆囊单层柱状上皮和粘膜、结肠粘膜、小肠粘膜和绒毛、肝脏、直肠腺体、胃粘膜、肾上腺束状带、甲状腺滤泡、脾索、胸腺小叶间隔、皮肤真皮层和汗腺、睾丸白膜和间质、脑组织内神经元和神经胶质、肺小支气管和肺泡、骨骼肌、肾脏皮髓质和肾小管、子宫内膜、胰腺腺泡和胰岛、卵巢、输卵管粘膜等绝大多数组织细胞。

They were diagnosed as chronic tubulointerstitial nephropathy accompanied with renal tubular acidosis, renal glucosuria, hyposthenuria and different degree of chronic renal dysfunction.

结果：9例均为中老年患者，临床上均表现为慢性小管间质性肾病，均有肾小管酸中毒、肾性糖尿、低渗尿和不同程度的慢性肾功能减退。

Results: Expression of PAI-1, TIMP-1 and FN in kidney of diabetic rats began to increase in the second week of diabetes; PAI-1 and TIMP-1 mainly expressed in intracytoplasm of renal tubular epithelial cells, while FN mainly expressed in renal tubule matrix and glomerului; Their expression showed a tendency of increasing along with the progression of diabetes.

结果：PAI-1、TIMP-1及FN表达从糖尿病2周起较正常对照组明显增多(P.01)，PAI-1和TIMP-1阳性表达主要位于肾小管上皮细胞胞浆内，FN阳性表达主要位于肾小管间质和肾小球，且随着糖尿病进展有逐渐增加的趋势。

TGF-β1 was mainly expressed in renal tubular epithelial cells, and there was no differece between proximal tubule and distant tubule. The expression of TGF-β1 was also increased with the development of tubulointerstitial lesions.

TGF-β1的表达亦主要见于肾小管上皮细胞，在近曲小管和远曲小管之间无明显的差异，TGF-β1的表达量也随着肾小管间质损害程度的加重而增加。

Methods Dietary-induced hyperlipidemia were induced in female SD rats by given 4% cholesterol and 1% cholic acid diet for 16 weeks.

用含4%胆固醇和1%胆酸钠的高脂饲料饲喂大鼠建立高脂模型，观察大鼠血脂、24h尿蛋白、血肌酥和肾小管间质病理改变，免疫组化法检测肾小管上皮细胞巢蛋白和α-平滑肌肌动蛋白表达。

Theurinary IL-6 level positively correlated with density of glomerular matrix membrane, global sclerosis, fiber or fibrocellular crescents and interstitial fibrosis (p. 05). According to the degree of density of glomerular matrix membrane and interstitial fibrosis, urinary Col-IV level had better correlation than urinary TGF-betal and IL-6 levels.In IgAN, Col-IV showed increased expression in diseased renal tissue whereas the site of expression of TGF-betal was mainly localized within the cytoplasm of tubular epithelial cells. Interstial expressionwas also present but glomerular TGF-betal expression was found only in patients with heavy mesangial proliferation. There was a significant correlation between glomerular positivity for Col-IV and severity of histological damage. There was also a significant correlation between positivity for TGF-betal and Col-IV in the tubular epithelial and interstitial lesions. In contrast, there was no ralationship between glomerular positivity for TGF-betal and severity of histological damage.The urinary TGF-betal level paralleled tubular TGF-betal expression.

结果 ①IgAN患者尿TGF-β1、IL-6、Col-Ⅳ水平较健康人明显增高(P＜0.01)，该变化与血中的浓度无关(P＞0.05)；②尿TGF-β1水平与小管间质TGF-β1阳性表达呈正相关(P=0.000)，而与小球TGF-β1阳性表达无关(P＞0.05)，尿Col-Ⅳ水平与小球和小管间质Col-Ⅳ阳性表达均呈良好的相关性(P＜0.01)，还与小管间质TGF-β1阳性表达呈正相关(P＜0.05)：③小球Col-Ⅳ阳性表达与肾组织慢性病变密切相关(P＜0.05)，小管间质Col-Ⅳ和TGF-β1阳性表达均与肾小管间质病变呈良好的相关性(P＜0.01)，而小球TGF-β1阳性表达与肾组织损伤无关(P＞0.05)；④尿TGF-β1、Col-Ⅳ水平与肾小球基质基底膜面密度、小管间质病变呈正相关(P＜0.01)，与小球内细胞数呈负相关(P＜0.05)，该结果与其在组织中的表达一致；尿IL-6水平浙江大学硕士学位论文尿TGF一B一、IL一6和Col一IV在IgA肾病中的应用价值与基质基底膜面密度、球性硬化、纤维或细胞纤维新月体所占肾小球百分数及小管间质病变均有显著的相关性(F.05)；在轻度肾病理损伤时，尿'l'G卜pl、I卜6、Col一IV水平即升高，而尿Col一W在反映细胞外基质积聚和间质纤维化程度上比尿TGF一pl和IL一6有更好的相关性。

Intrarenal CRP level but not serum CRP is closely associated with TIF in chronic CsA nephrotoxicity.

本研究通过检测大鼠血CRP水平，探讨了其与慢性CsA肾毒性肾小管间质纤维化间的关系。

BSA can induce ACE up-regulation in proximal tubular cells, which may lead to the increased production of local AngⅡ and finally contributes to the intrarenal activation of renin angiotensin system.

BSA可显著增加HK-2细胞ACE表达，此作用可能是导致肾间质局部AngⅡ蓄积从而启动肾小管间质纤维化的重要机制之一。

Objective: To explore the effect and happening mechanism of hdrochloric acid kukoline for the treatment of renal interstitial fibrosis,to supply some according for clinic how to resist glomeruli and nephric tubule interstitial fibrosis.

目的：探讨盐酸青藤碱在治疗肾间质性纤维化中的作用及其发生机制，为临床如何阻止、防止肾小球和肾小管间质纤维硬化提供借鉴。

Histologically, the seminiferous tubules contained numerous Sertoli cells and more Sertoli-spermatozoa complexes, accompanied by the depletion of Leydig cells with deeply stained nuclei. Mature spermatozoa were stored up in the epididymis, but only a few in the efferent ducts. In the second place was testicular atrophy（32/120; 26.7%）. The seminiferous tubules showed moderate to severe inactivity of spermiogenesis with evidence of only spermatogonia, spermatocytes and Sertoli cells. The Leydig cells were obviously decreased in numbers associated with decrease of lipid droplets in their cytoplasms. Testicular hypoplasia was the third disorders（22/120; 18.3%）. Only a few spermatogonia and Sertoli cells appeared without any spermiogenesis. The associated changes was decreased in Leydig cells and fibrous hyperplasia in the interstitium.Epididymal stones were sometimes found（12/120; 10%）. Grossly, yellowish-white nodules with various sizes and firm in consistency were observed in the epididymis and the front efferent ducts. Microscopically, the epididymal ducts were dilated with voluminous spermatozoa storage, even showed calcification in severe cases. The deposited calcium salts were stained positively by Von Kossa and Alizarin red methods.Amyloidosis was also detected in 10 roosters（8.3%）. Eosinophilic, homogeneous, amyloid-like substances were deposited mainly in the testicular interstitium and the periphery of blood vessels. These substances showed positive reaction by Congo red staining. Five roosters（4.2%）had Marek's lesions in the testis, epididymis and peripheral nerves with infiltration of pleomorphic lymphocytes. Only one case showed epithelial necrosis of seminiferous tubules accompanied by fibrous proliferation in the interstitium.

结果发现，在总共搜集的120个病例中，其中因年老所导致的产精力不佳为最多，占38例（31.7%），於镜下可见大量精虫黏附於Sertoli cell的表面，并可见Sertoli cell数量明显增多而Leydig cell明显减少，且其细胞核呈现浓染的现象，而在其副睪中仍可见到成熟精虫蓄留於管腔中，但在其输精管内却只有少量精虫存在；其次为睪丸萎缩，占32例（26.7%），镜下可见中度至重度无造精作用，其生精小管中只见到精母细胞、精原细胞及Sertoli cell存在，但Leydig cell数量明显减少且其细胞质内的脂质也明显减少；睪丸发育不全，占22例（18.3%），於生精小管内只见到精母细胞及少量Sertoli cell存在，不见造精细胞分化，於生精小管间质可见Leydig cell减少并伴随结缔组织增生；副睪结石，占12例（10%），肉眼下可在副睪及输精管前段见到黄白色大小不一的结节，触感坚硬，於镜下可见副睪管扩张并有大量成熟精虫蓄积，严重时可见钙化现象，以Von Kossa及茜素红染色均呈阳性反应；类淀粉沉著症，占10例（8.3%），镜下在睪丸间质及血管周围可见粉红均质样的物质沉积，以刚果红染色成阳性反应；马立克病，占5例（4.2%），镜下可在睪丸、副睪实质及周边神经内均可见到嗜碱性大小不一的淋巴样细胞浸润；睪丸坏死，占1例（0.8%），镜下可见生精小管上皮细胞坏死脱落及间质结缔组织增生。

与小管间的相关的网络解释 [注：此内容来源于网络，仅供参考]

AIN：急性间质性肾炎

急性间质性肾炎(AIN)又称为急性肾小管-间质性肾炎,是一组以肾间质(炎细胞浸润)及小管(退行性变)急性病变为主要表现的疾玻临床表现一、全身过敏表现常见药疹、药物热及处周血嗜酸性粒细胞增多慢性间质性肾炎(CIN)又称慢性肾小管间质性肾炎是一组以肾小管萎缩和肾间质纤维化慢性病变为主要表现的疾玻早期以肾小管功能损害为主

Bloop tube：准星延伸管

从前瞄准具(准星)到后瞄准具(照门)间的距离 长度越长 瞄准时视觉误差的影响越小. 现代射击竞赛中常加装准星延伸管(bloop tube) 以增加瞄准基线长度.

centriole：中心粒

5.中心粒(centriole)这种细胞器的位置是固定的,具有极性的结构. 在间期细胞中,经固定、染色后所显示的中心粒仅仅是1或2个小颗粒. 而在电子显微镜下观察,中心粒是一个柱状体,长度约为0.3μm~0.5μm,直径约为0.15μm,它是由9组小管状的亚单位组成的,

interstitial nephritis：间质性肾炎

间质性肾炎(interstitial nephritis)是以组织学特点而命名的一组肾实质疾病,指由于多种病因引起的具有广泛肾间质炎性细胞浸润和不同程度的肾小管退行性病变而肾小球、肾血管基本正常为病理特征的肾实质疾病;因常伴有不同程度的肾小管病变和功能障碍,

tubular proteinuria：肾小管性蛋白尿

2.肾小管性蛋白尿(tubular proteinuria)是由于肾小管对滤出蛋白的回吸收障碍所致. 见于肾小管间质病变、肾盂肾炎、先天性肾小管病、低钾肾病等. 此类蛋白尿的特点为尿蛋白总量通常较少,一般<1g/d;且仅含少量白蛋白,

seminiferous tubules：生精小管

尤其有趣的是,该病毒还可以感染生精小管(seminiferous tubules)的上皮生殖细胞(epithelial germ cells)和间质的巨噬细胞,并导致精细胞的缺损和死亡(一种细胞程序性死亡,apoptosis),而大量的未成熟的精细胞便成了PRRSV的携带者;

stone canal：石管

环管于一间步带处向反口面伸出一石管(stone canal)(位于轴器内),管壁内有石灰质环,故较硬,管末端连于筛板,与外界相通. 筛板为一圆形小骨板,其上有许多辐射排列的小沟纹,沟底有许多小孔(约200个). 环管上间步带处各具一对帖德曼氏体(Tiedmann's body,

nephrosclerosis：肾硬化

肾硬化(nephrosclerosis)是高血压病患者肾脏活检或尸检标本典型的组织学表现. 就肾组织病理形态学而言,高血压造成的肾组织病变,无论是肾小球、小管-间质,还是球外的血管损伤并不具有显著的特征. 即无论是普通光镜,

trabeculae：连接小管

贯穿整个链体.节片成熟后,节片间的肌纤维会逐渐退化,导致孕节自链体脱落.肌层下的实质结构中有大量电子致密细胞称为核周体(perikarya).核周体通过若干连接小管(trabeculae)穿过表层肌和基膜通向皮层.核周体的细胞核具有双层膜,

Tularaemia unspecified：未特指的土拉菌病

输卵管或输精管绝育术后成形术 Tuboplasty or vasoplasty after previous ster... | 肾小管-间质肾炎,未特指急性或慢性 Tubulo-interstitial nephritis not spec as acute... | 未特指的土拉菌病 Tularaemia unspecified