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KPF can be dispersed amorphously with the KPF/EC ratio 1∶2 and 1∶3. The release profiles of the drug can be fitted the Higuchi model. By increasing the amount and viscosity of EC, and increasing the particle size of the solid dispersions from 200 600 μm, the release rate can ...
体外释放度试验结果表明,药物体外释药行为均符合Higuchi 方程;缓释效果与EC 量和固体分散体的粒径有主要关系,药物释放速率随EC 用量和粘度增加而减小;固体分散体粒径越小药物体外释放速率越快;在pH 6 。8 介质中的体外释放速率高于在pH1 。2 介质。
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The results showed that there was no significant difference in three structure approach of liquid layers among which B was relatively higher;and it was considered that one-step dilution was an effective preservation method in that survival capacity with frozen and melted embryos freshly split,and survival capacity of frozen and melted IVF embryos split by one-step dilution by application minimum capacity refrigerant method with specific canaliculus were obviously higher than B.
结果,3种不同液体层构成间胚胎的存活能力无显著差异,B法较高;应用特定细管最小容量冷却法在冷冻溶解的新鲜分割胚、体外受精分割胚及冷冻溶解的体外受精分割胚一步法稀释后的存活能力均显著高于B法。结果表明,特定细管最小容量冷却法是更有效的保存方法。
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Methods To investigate the ability of proliferation of the three lung cancer cell lines:the cell line L9981 of human high metastasis lung cancer,the cell line L9981-nm-H1 of transfected nm23-H1 gene,and the cell line L9981-pLXSN of transfected vector using MTT methods,and to examine the ability of extro-invasion of the three cell lines above using improved B...
方法应用放免法检测人高转移大细胞肺癌原代细胞株L9981,转基因细胞株L9981-nm23-H1和空载体转染细胞株L9981-pLXSN的PKA的活性,应用MTT法检测L9981,L9981-nm23-H1和L9981-pLXSN细胞株的体外增殖,改良的Boyden小实法检测L9981,L9981-pLXSN,L9981-nm23-H1这3个细胞株细胞体外侵袭力。
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By submerged liquid fermentation technology glycinin with macromolecular weight are broken down into peptides with smaller molecular weight, and by which a process of protein decomposition as well as peptide synthesis are achieved.
项目简介:该项目是利用现代生物技术,通过深度的液态发酵,将大分子的大豆球蛋白分解为小分子的肽,完成动物体外分解蛋白合成肽类物质的过程。
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Degradation test in vitro was carried out in phosphate buffer solution (0.1M, pH7. 4) at 37 ℃. The buffer solution was changed daily. Degradation test in vivo was implanted the sample to subdermal in adult ICH rat in the scapular area lateral to the dorsal midline. At suitable time the samples were recovered. Molecular weight changes in surface layer and bulk of polymer sample were measured by GPC and weight loss was determined gravimetrically. It was found that the degradation behavior can be regulated by changing the composition of copolymers. The critical compositions from surface to bulk degradation behavior for PGCA, PLCA, PLMCA, PLDCA systems were 15-20, 20-30, 30- 40, 40 of mol percent GA or LA unit in copolymers, respectively. The degradation behavior of PGCA, PLCA, PLMCA, PLDCA systems were compared and analysed. Some factors influencing the degradation character, such as copolymer composition, hydrophobicity, crystallinity and enzyme affect etc. played important role.
体外实验中材料降解环境为37℃,0.1M,pH7.4磷酸缓冲溶液,每天换液,定期取样;体内实验中将聚合物试样埋置于ICH小白鼠背部肩胛骨皮下部位,定期处死小鼠,取样,将体内体外样品进行重量损失及试样内外层分子量变化测定,分析各聚合物试样降解行为特性,实验结果证明,改变共聚物组成,可以调节各聚合体系降解行为特性,对PGCA,PLCA,PLMCA,PLDCA共聚体系,交酯摩尔百分含量15-20%,20-30%,30-40%,40%分别为各体系内降解行为特性由表面降解型向本体降解型过渡的临界转折点,交酯含量较低的聚合物不同程度地表现表面降解行为特性,论文对各共聚体系体内外降解行为作了分析对照,例如共聚物组成对材料降解速度与降解行为的影响;生物体内酶对降解行为的影响;材料亲疏水性,聚合物链段结晶行为及碳酸酯结构对材料降解行为的影响等,得出交酯/环碳酸酯共聚体系降解行为一些共性和规律。
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The main outcome measure was the ability of rpe cells to phagocytize the vesicle numbers of silicone oil in vitro.
测量人rpe细胞在体外吞噬硅油小滴的数量。
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The proliferative capacity of LEC from human had directly relevance to the age of donor(r=-0.996).Conclusions The formation of lens-like spherules is characteristics of LEC lines in the cultured cells.Under identical conditions,the proliferative rate of LEC from bovine and rabbit is fast than that of LEC from human,but dedifferentiation of LEC from bovine and rabbit is easier than that of LEC from human;LEC from the three species exhibit similar limited growth potential.The proliferative rate of LEC from human has a inversely proportion with age.
&晶状体小体&的形成可作为确定晶状体上皮细胞株的一项特征性依据,而体外培养的人、牛、兔晶状体上皮细胞具有相同的有限生长潜能,在相同的条件下,牛、兔晶状体上皮细胞的生长增殖速度比人晶状体上皮细胞快,但易于发生去分化;此外,人晶状体上皮细胞的生长增殖率与年龄密切相关,年龄越小,晶状体上皮细胞的生长增殖速度越快。
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MethodsThe minimal inhibitory concentration and time-killing rate of different sizes of polyethylanimine, alone and in combination with the drugs against two isolates of Candida albican were investigated.
通过体外实验测定不同分子质量聚乙烯亚胺单独及与三种不同类别的常规抗菌药物联合使用对两株白念珠菌的最小抑菌浓度和杀灭时间,确定PEI单独及联合使用的体外抗真菌活性。
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The result showed that the biodegradation rate of calcium phosphates powders decrease in the order: ACP>α-TCP≈α-TCP/HA>HA, ACP>α/β-TCP>α-TCP>β-TCP, This indicates that the biodgradation rates of calcium phosphates prepared in this thesis can be tailorable.
实验结果表明:这些粉末的生物体外降解速率由大到小的顺序为:ACP>α-TCP≈α-TCP/HA(1:1)>HA,ACP>α/β-TCP(1:1)>α-TCP>β-TCP;纳米结构化复相磷酸钙现示出降解速率可调性和独特性,如α/β-TCP(1:1)的生物体外降解速率大于α-TCP单相。
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Heating, ethanol precipitation, and ion-exchange chromatographies had been carried out to isolate the protein with specific stimulating activity from newborn calf liver, and [(3)H]thymidine deoxyribose/bromodeoxyuridine incorporation and carboxyfluorescein diacetate succinimidyl ester-based proliferation assay to determine the bioactivity in vitro and in vivo.
通过用加热、乙醇沉淀、离子交换层析等方法来分离新生小牛肝脏中含有特殊刺激活性的蛋白和用胸嘧啶脱氧核糖/溴脱氧尿苷联合羧基荧光素双乙酸钠琥珀酸酯为基础的扩增分析其体内和体外的生物活性。
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Berberine:小檗碱
1.2 小檗碱 小檗碱(berberine)为黄连(毛茛科植物)、黄柏等(芸香科植物)植物的一种生物碱,作为抗菌药已有悠久的历史. 初步研究表明它在体内、体外对多种肿瘤细胞具有较强的抑制和杀伤作用[2].
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excretion:排泄
(五)排泄 排泄(excretion)是药物及其代谢物排出体外的过程.药物的生物转化和排泄统称为 消除(elimination).药物排泄的主要途径为经肾脏随尿排出.游离的原型药物和代谢物 均可通过肾小球毛细血管壁小孔隙滤入原尿中, 也有少数弱酸,
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necropsy:尸体检查
绕开皮肤从体外用中空的针刺入体内各器官,以取得检查用材料的方法. 亦称活体检查,是解剖检查(antopsy)或尸体检查(necropsy)的对应词. 有吸取象骨髓那样液体组织的方法和用特殊的中空针采取象肾脏、肝脏、脾脏那样组织小片的方法.
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nephrostome:肾口
每一肾小管的一端以带有纤毛的漏斗形开口,即肾口(nephrostome),开口于体腔,另一端汇入原肾管,原肾管的后端通向体外. 体腔液中的代谢废物即由肾口汇入原肾管,最后排出体外. 这种理论上的最原始肾脏称为全肾或原肾. 在现代生存的动物中,
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Spawn Broodling:体外寄生(专对地面部队的必杀寄生虫),还会残留两只小虫
Plague:目标生命值下降至濒死. | Spawn Broodling:体外寄生(专对地面部队的必杀寄生虫),还会残留两只小虫. | power overwhelming:无敌;
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Spawn Broodling:体外寄生(专对于地面部队的必杀寄生虫),还会残留两只小虫
Plague:目标生命值下降至临近死亡. | Spawn Broodling:体外寄生(专对于地面部队的必杀寄生虫),还会残留两只小虫. | power overwhelming:无敌;
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tubular:管
人类的肾脏每天通过的水分大约有一百五十公斤,这些水分都须经过肾小球(Glomerulus是血液超微过滤的场所)和肾小管(Tubular)的过滤和筛检;真正以尿液的方式排出体外的部分,才只有一十五公升,约占百分之一,由此可知肾脏工作负担的沉重.
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extracorpuscular:小体外的
extracode 附加码 | extracorpuscular 小体外的 | extractableextractible 可引出.可拔取的
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extracorpuscular:小体外的 细胞外的
extracoronalretainer冠外固位体 | extracorpuscular小体外的 细胞外的 | extracranialencephalometer颅外测脑器
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extracorpuscular:小体外的,血球外的
细胞外的 extracellular | 小体外的,血球外的 extracorpuscular | 浸膏,萃取物,抽出物 extract