- 更多网络例句与哇巴因相关的网络例句 [注:此内容来源于网络,仅供参考]
-
Aim To observe the effects of ouabain and aconitine on APD and ion channels in isolated guinea pig and rat ventricular myocytes; to elucidate the action mechanisms of these two drugs and set up new arrhythmic models on cellular level.
目的 观察哇巴因和乌头碱对豚鼠和大鼠心肌单细胞离子通道的作用,确定两药诱发心律失常时离子靶点和最佳靶点,建立细胞水平的心律失常模型。
-
A large quantity of evidence has showed that higher EO might be one of the pathogenic factors of hypertension. EO also referred to endogenous sodium pump inhibitor, endogenous digitalis-like substance or endogenous digoxin-like factor before, is a recently identified sterone hormone that might be secreted from adrenal cortex.
内源性哇巴因(endogenous ouabain, EO)是新近发现主要由肾上腺皮质所分泌的一种类固醇激素,大量证据表明,体内EO含量升高可能是高血压的发病因素之一。
-
Methods Animals were randomly and equally divided into five groups: saline control group, positive drug control group, low-dose, medium-dose and high-dose crocetin group. Animals were anesthetized with urethane (1.2 g/kg), then followed by the perfusion of aconitine (10 μg/mL) through caudal vein in rats, or of ouabain (9 μg/mL) through external jugular vain in guinea pigs in a constant velocity of 0.1 mL/min, and the emergence time of ventricular fibrillation, ventricular extrasystole, ventricular tachycanlia and cardiac arrest were then detected and recorded. The recorded time was then translated to the cumulated amount of aconitine and ouabain. Experimental arrhythmia was induced by rapid injection of 4% CaCl2 (140 mg/kg), and the emergence time, persistence time, incidence and death of arrhythmia after the administration were observed.
将实验动物随机分为生理盐水组,阳性药物对照组,藏红花酸高、中、低剂量组,SD大鼠采用1.2 g/kg乌拉坦麻醉后,从尾静脉匀速(0.1 ml/min)灌注10μg/ml乌头碱溶液,豚鼠麻醉后从颈静脉匀速(0.1 ml/min)灌注9μg/ml哇巴因溶液,观察出现室性期前收缩、室性心动过速、室颤和心脏停搏的时间,然后换算成乌头碱和哇巴因的累积量;快速推注4%氯化钙(140 mg/kg)诱导大鼠心律失常,观察给药后心律失常出现时间、持续时间、心律失常发生数及死亡数。
-
These suggested that SOD and Se decreased the toxicity of the heart induced by Ouabain i...
本结果提示SOD和Se对离体心脏由哇巴因所诱发的心律失常有不同程度的对抗作用,推测自由基可能参与哇巴因致离体心脏的中毒过程。
-
This study was aimed to investigate the effects of ouabain at low concentrations on growth regulation in various leukemia cell lines and to determine the therapeutic potential of ouabain in leukemia.
本研究目的在于通过研究低浓度哇巴因对不同白血病细胞株生长的影响,探讨哇巴因用于白血病临床治疗的可行性。
-
Positive inotropic effects and safety margin of milrinone had been compared with ouabain on ailing heart model in cats and guinea-pigs.
在猫和豚鼠戊巴比妥钠心衰模型上比较了米利酮和哇巴因的强心作用、安全范围和心脏毒性。
-
According to the fact that EO has played an important role in the development of hypertension, we put forward a hypothesis that ouabain antibody might reduce blood pressure. It was confirmed the blood pressure was dropped down for 3 hours after 1k1c hypertensive rats was injected with ouabain polyclonal antibody for 3 hours.
EO在高血压的发生中起着较为重要的作用,由此我们提出了哇巴因抗体可能具有降压作用的假说,并在对1k1c高血压大鼠静脉注射哇巴因多克隆抗体后3小时的血压连续观察中证实了该假说。
-
Methods The experimental arrhythmia models were induced with barium chloride (BaCl2),uabaina and aconitine in rats and cobayaes.The incidence rate and mortality rate of arrhythmia,the emergence time and the duration of arrhythmia induced with BaCl2 were recorded in rats pretreated with CASI (in dosages of 25,50, and 100 mg·kg-1 sublingual vein injection).At the same time,the dosages of uabaina and aconitine were observed when the ventricular premature contraction,ventricular tachycardia,ventricular fibrillation and cardiac asystole were appeard in rats and cobayaes pretreated with CASI (in dosages of 25,50, and 100 mg·kg-1 sublingual vein injection).
制备氯化钡(BaCl2)、哇巴因及乌头碱诱导的大鼠及豚鼠实验性心律失常模型,CASI按25、50、100 mg·kg-1分为3个剂量组,舌下静脉给药1次,不给CASI作为对照组,记录大鼠给BaCl2后心律失常的发生率、出现时间、持续时间及动物的死亡率;观察豚鼠及大鼠出现室性早搏、室性心动过速、心室颤动及心脏停搏时哇巴因及乌头碱的用量。
-
Because ouabain polyclonal antibody made blood pressure reduced for shorter time and possessed slightly allergy, we aimed to prepare a new depressor, ScFv, with high specificness by advanced phage display technique. The heavy-chain and kappa light-chain variable region gene repertoir of immunoglobin were amplified individually with heavy chain and light chain primers of Pharmacia Corporation and assembled into ScFv by a linker with overlap extension PCR.
针对哇巴因多克隆抗体存在的降压时间持续较短及存在轻微的过敏反应等缺点,本研究利用先进的噬菌体抗体库技术,拟研制开发一种具有高度选择性的降压新药--哇巴因单链抗体。
-
RESULTS Ouabain-like immunoreactivities were observed abundantly in the inner zone of adrenal cortex, known as the zone reticularis of SD rats and Macaca mulattas; weakly in the posterior pituitary of SD rats, but nothing in the hypothalamus.
结果 在大鼠和恒河猴的肾上腺皮质内侧网状带细胞中可以观察到丰富的哇巴因免疫反应阳性物质,垂体后叶有较弱的哇巴因免疫反应阳性物质,而下丘脑并未发现有哇巴因免疫反应物质存在。
- 更多网络解释与哇巴因相关的网络解释 [注:此内容来源于网络,仅供参考]
-
ouabain:哇巴因
中文摘要 哇巴因(ouabain)是一种强心配醣体,研究指出强心配醣体在缺血性脑中风实验模式具有神经保护作用. 丹参是一种中药材,其水萃物主要成分酚酸B镁盐(MLB)被证实具有类似哇巴因的作用,且能减少脑中风动物之脑梗塞面积,
-
ouabain:abbr. oua; 观察哇巴因
-
G Ouabain:哇巴因, 乌巴因, 苦毒毛旋花子甙 毒毛花苷
奥芬那君杂质E Orphenadrine impurity E | 哇巴因, 乌巴因, 苦毒毛旋花子甙 毒毛花苷G Ouabain | 苯唑西林钠一水合物 Oxacillin sodium monohydrate
-
outer diameter:外直径
ouabain 哇巴因 | outer diameter 外直径 | outer flame 外焰
-
Oleandrin:夹竹桃苷
文章摘要:强心甾类固醇(cardiotonic steroids,CTS)是一类能与真核细胞膜钠泵(sodium pump,Na^+,K^+-ATPase)特异性结合的化学物质,种类繁多,包括植物来源的洋地黄类如地高辛(digoxin)、哇巴因(ouabain)、夹竹桃苷(oleandrin)、嚏根草苷(hel