同种组织移植的

基本解释 (translations)

allogenic

与同种组织移植的相关的网络例句 [注：此内容来源于网络，仅供参考]

BACKGROUND: Currently, the materials used in clinical practice to repair cruciate ligament of knee joint contain auto-graft bone- mid 1/3 patella tendon-bone, auto-semitendinous muscle, gracilis muscle and allogenic tissue graft. All of them are limited to a certain degree in clinical application.

背景：目前临床上修复膝关节叉韧带断裂的材料有自体膑腱、自体半腱肌和股薄肌，以及同种异体组织移植等，但这些方法都存在一定的局限性。

With the establishment of animal models of aortic homograft transplantation, using immunohistochemical staining, the difference of the expression of MHC Ⅰ antigen and MHC Ⅱ antigen was detected between fresh aortic homografts and cryopreserved ao rtic homografts.

建立大鼠同种异体主动脉移植模型，采用免疫组织化学实验研究新鲜主动脉和低温保存的主动脉同种异体移植后MHC Ⅰ类抗原和MHCⅡ类抗原表达的区别。

Historically, isolated FCL injuries have been treated by direct repair,2 augmentation with a strip of the common biceps tendon,3,38 augmentation with a portion of the iliotibial band,3 imbrication and advancement with a bone block,7,13 or reconstruction using allograft tissue at nonanatomic attachment sites.4,6,24,29 However, to our knowledge no anatomic approach to reconstructing nonrepairable isolated FCL injuries has been published.

过去FCL离断伤通过直接修复[2]、股二头肌总腱增强[3，38]、部分髂胫束增强[3]、骨块重叠改良[7，13]或同种异体组织移植在非解剖重建治疗[4，6，24，29]。然而，就我们所知，尚未发现不可修复的FCL离断伤后解剖学重建的报道。

ObjectiveTo assess the relationship of the expression of bcl-2/bax and the acute rejection of small intestine transplantation ,And open up news pathway for diagnosising acute rejection of small intestine transplantation in earlier period-MethodsCreated 36 rat model of allogene small intestine transplantation by using inbred rat Wistar/A and F344/N.

目的 建立同种异基因大鼠小肠移植模型，检测术后移植小肠组织内凋亡基因Bcl-2和Bax的表达情况，探讨其与急性排斥反应之间的关系，为临床早期诊断急性排斥反应开辟新途径。方法选用近交系F_(344)／N和封闭群Wistar／A大鼠建立全小肠移植模型。

Get high purity DCs by Cultured plastic-adherent monocytes isolated from healthy human peripheral blood with GM-CSF and IL-4 for 7 days. To observe the morphology of DCs by inverted phase contrast microscope ,electron microscope and laser confocal microscope. Analyse phenotype of DCs with flow cytometry. Investigate the endocytosis ability of DCs as a group by Horseradish peroxidase endocytosis assay. To appraise allogeneic mixed lymphocytes reaction of DCs by MTT reduction assay. Analyse the levels of IL-12 and TNF in liquids of cultured medium by ELISA and MTT reduction assay respectively. Soluble antigens of HCCs was obtained by 3 freeze-and-thaw cycles. Biological characteristics of HC soluble antigens pulsed DCs were monitored by flow cytometry. According to MTT reduction assay estimated the cell proliferation of self lymphocytes activated by HC antigens pulsed DCs. Get high purity BCG HSP 70 protein by SDS-PAGE electrophoresis and determined its biological activity with ELISA. Analyse phenotype of antigen pulsed DCs primed by BCG HSP70 with flow cytometry. By MTT reduction assay estimated the cell proliferation of self lymphocytes and the MLR of DC based vaccine. Analyse expression of HLA-DR molecule on surface of HCC lines. The IFN-γ mRNA in lymphocytes after actived by DC vaccine and the Fas-L expression on DC and DC vaccine primed lymphocytes were detected by in situ hybridization and flow cytometry respectively. Specific cytotoxity lysis of T lymphocytes and nonspecific inhibition of liquids in culture medium against HCC lines were also tested. Detect expression of hAFP on four HCC lines with Cell-ELISA. Induce apoptosis of HCCs with actinomycin-D. Interaction of DCs and apoptotic cells was observed under transmission electron microscope. Growth inhibition test of DC against HCC lines was also performed. Establish the nude mouse model bearing human HC xenografts and indentify the characteristic of tumour by histochemistry and immunohistochemistry techniques. Prevent and treat transplanted human HC on nude mouse with Freezing and anabiotic HC specific lymphocytes.

用GM-CSF和IL-4从健康人外周血诱导DC；分别用倒置相差显微镜、电子显微镜及激光共聚焦显微镜观察DC形态；流式细胞术检测DC表型；HRP吞噬实验测定DC的群体内吞能力；MTT法检测同种异体混合淋巴细胞反应；ELISA法和MTT法分别测定DC培养上清液中IL-12和TNF水平；冻融法制备肝癌细胞可溶性抗原；流式细胞术检测负载肝癌可溶性抗原后DC的生物学特性；MTT法检测DC负载肝癌抗原后对自身淋巴细胞增殖的影响；SDS-PAGE制备电泳纯化BCG HSP70并鉴定纯度，ELISA测定活性；流式细胞术检测负载抗原DC经BCGHSP 70活化后的表型；MTT法检测肝癌DC疫苗对自身淋巴细胞增殖的影响和混合淋巴细胞反应；流式细胞术检测肝癌细胞表面HLA-DR表达；MTT法检测肝癌DC疫苗对自身淋巴细胞的活化；原位杂交法检测肝癌DC疫苗活化后的淋巴细胞IFN-γmRNA表达；流式细胞术检测DC和肝癌DC疫苗活化后淋巴细胞表面Fas-L；MTT法分别检测肝癌DC疫苗活化的淋巴细胞和其培养上清对肝癌细胞的特异性杀伤和非特异性抑制作用；Cell-ELISA检测人肝癌细胞hAFP表达；MTT法检测负载AFP表位肽和凋亡肝癌细胞DC对自身淋巴细胞增殖的影响；ELISA法和MTT法分别测定活化后淋巴细胞培养上清中TNF和IL-12水平；肝癌细胞凋亡的诱导和检测；DC吞噬凋亡肝癌细胞后的电子显微镜观察；DC对肝癌细胞的生长抑制试验；人肝癌裸鼠皮下移植瘤动物模型的建立及其组织学和免疫组织化学鉴定；DC及肝癌特异性淋巴细胞预防和治疗人肝癌裸鼠皮下移植瘤；冻存和复苏后的肝癌特异性淋巴细胞预防和治疗人肝癌裸鼠皮下移植瘤。

Results:pedunculated omentum majus-cirded trachea transplantation ensured an early re-establishment of blood circulation of transplanted trachea and maintenance of its normal animate states; allogeneoilc transplantation of trachea activated bodys immune mechanism. resulting in a chronic process of rejection and finally leading to progressive necrosis of transplanted trachea tissues: chondroregeneration occurred at every period under perichondrium after transplantation. and the degree of regeneration was related with favorable blood circulation; the emplogyment of a supporting tube in trachea,under the condition of favorable re-establishment of early blood circulation, could preventgranulation tissue hyperplasia and keep trachea cavity unobstructed.Postgraduate Ding XiaoQuan Directed by-Lin LeShen

结果 带蒂大网膜包绕移植段气管行腹腔移植，早期重建了移植段气管的血液循环，保证了移植气管的早期成活及维持其正常生机状态；同种异体气管移植所激发机体的免疫机制，引起一个慢性排斥反应过程，导致移植段气管组织进行性坏死；软骨再生存在于移植后各个时间段，其再生程度与良好的血液循环有关；气管内支撑管的应用可防止肉芽组织增生堵塞管腔，从而保证气管管腔通畅。

Allogeneic and syngeneic fresh bone, autolyzed antigen-extracted bone, bone matrix gelatin, demineralized bone matrix were implanted into the muscle pouch of mice, at different times after implantation, the immunological, histological and alkaline phosphatase assay were conducted. The results revealed that all four kinds of allogeneic implants activated specific cellular and humoral immune responses, most notably in fresh bone group, the AAA, BMG and DBM inhibited the proliferation of the lymphocytes in vitro and BMG had the most powerful inhibiting action, allogeneic AAA, BMG and DBM might induce heterotopic osteogenesis in vivo, however, there were obvious difference in ALP and histomorphometry between allografts and isografts.

在小鼠肌肉内植入同种异体或同系新鲜骨、自消化抗原去除骨、骨基质明胶、脱钙骨基质，术后免疫学、碱性磷酸酶、组织学检查发现：4种同种异体植入物均可引发特异性细胞免疫反应和体液免疫反应，其中以新鲜骨移植引发的免疫反应最为显著；自消化抗原去除骨、骨基质明胶、脱钙骨基质在体外具有抑制淋巴细胞增殖的作用，骨基质明胶对淋巴细胞增殖的抑制作用最显著；同种异体与同系4种植入物在体内成骨活性有显著差异；自消化抗原去除骨、骨基质明胶、脱钙骨基质均有异位诱导成骨活性，其中骨基质明胶骨诱导活性最佳。

With the establishment of animal models of aortic homograft trans-plantation,using immunohistochemical staining,the differ-ence of the expression of MHCⅠantigen and MHCⅡanti-gen was detected between fresh aortic homografts and cryop-reserved aortic homografts.

建立大鼠同种异体主动脉移植模型，采用免疫组织化学实验研究新鲜主动脉和低温保存的主动脉同种异体移植后MHCⅠ类抗原和MHCⅡ类抗原表达的区别。

How do we solve the alloimmunity caused by transfusion, one kind of tissue transplantation in essence, is the focal point for domestic and oversea scholars.

血液是结缔组织，输血的本质是一种非长期存活的组织移植。如何解决同种免疫排斥问题，各国学者作了大量工作。

In our research,Wistar rats and SD rats which were parathyroidectomized were used as donors and recepients respectively.The parathyroid gland of the Wistar rat were allografted into the cerebroventricle and other different sites of the brains in SD rat s tereotaxically. Using methods of testing serum Ca~(2+) concentration,histological examination,histochemical and immunocytochemical methods and electron microscopic observation,we investigated the survival of the grafting tissue,its revascularization, infiltrating of monocytes, changes of microglia and astrocytes, the relationship of the CNS with the immune system, and the mechanism of rejection were investigated.The results as following: I .Effects on PTG after allografting into cerebroventricle and cerebral parenchyma of the brain: Testing serum Ca~(2+) conc.

本研究以Wistar大鼠作为供体，切除甲状旁腺的SD大鼠作为受体，在立体定位下将同种异体的PTG移植到大脑的不同部位，设计了侧脑室-内分泌系统移植的代替途径，比较了侧脑室内移植和脑实质内移植的异同，通过测定血清Ca~(2+)的浓度、组织学检查、组织化学和免疫细胞化学以及电镜观察对移植后PTG组织的存活、血管的再生、单核细胞的浸润、CNS内胶质细胞的变化、对免疫系统的影响及免疫排斥的机制进行了研究，结果如下：一、同种异体PTG侧脑室内移植与脑实质内移植的比较：血清Ca~(2+)的检查发现，PTG侧脑室内移植后第7天，血清Ca~(2+)的浓度恢复到8mg％以上，一直持续到移植后第8-12周；移植后第12周仍有60％移植PTG的动物血清Ca~(2+)维持在正常水平。

与同种组织移植的相关的网络解释 [注：此内容来源于网络，仅供参考]

hyperacute rejection：超急排斥

超急排斥(hyperacute rejection)反应一般在移植后24小时发生. 目前认为,此种排斥主要由于ABO血型抗体或抗Ⅰ类主要组织相容性抗原的抗体引起的. 受者反复多次接受输血,妊娠或既往曾做过某种同种移植,其体内就有可能存在这类抗体. 在肾移植中,

Allograft：异体移植物

同种异体移植物(allograft)移植后常发生免疫排斥反应,引起这种排斥反应的抗原称为移植抗原或组织相容性抗原. 动物和人具有多种组织相容性抗原,根据引起排斥反应的移植抗原的强度将组织相容性抗原分为:(1)主要组织相容性抗原系统,

Allograft：同种异体移植物

同种异体移植物(allograft)移植后常发生免疫排斥反应,引起这种排斥反应的抗原称为移植抗原或组织相容性抗原. 动物和人具有多种组织相容性抗原,根据引起排斥反应的移植抗原的强度将组织相容性抗原分为:(1)主要组织相容性抗原系统,