同种抗原

基本解释 (translations)

isoantigen

与同种抗原相关的网络例句 [注：此内容来源于网络，仅供参考]

At the beginning, HLA class I/peptide complex teramer was prepared, including the most frequent alleles in Chinese, i.e., HLA-A2 and HLA-A24. Then the aAPCs were assembled by coating a cell-sized bead with pMHC and anti-CD28 antibody, which were able to provide the dual signals required for T cell activation, and used as stimulator to generate pMHC-specific CTL by co-culture with allogeneic peripheral blood lymphocyte.

首先制备包括我国人群基因频率最高的HLA-A2，HLA-A24的HLA/抗原肽四聚体，在此基础上，制备能够为T细胞提供第一、第二活化信号的aAPC，其表面包被的HLA/抗原肽复合物容易控制，用于诱导同种个体的T细胞产生同种CTL。

With the establishment of animal models of aortic homograft transplantation, using immunohistochemical staining, the difference of the expression of MHC Ⅰ antigen and MHC Ⅱ antigen was detected between fresh aortic homografts and cryopreserved ao rtic homografts.

建立大鼠同种异体主动脉移植模型，采用免疫组织化学实验研究新鲜主动脉和低温保存的主动脉同种异体移植后MHC Ⅰ类抗原和MHCⅡ类抗原表达的区别。

An isoantigen that on exposure to its corresponding isoantibody causes agglutination of the red blood cells to which it is attached.

同种凝集原；同族凝集原一个同种抗原，在接触它相应的同种抗体的会导致与其附在一起的红细胞发生凝集

The challenge of achieving improved monitoring of all transplant patients may allow tailoring of immunosupression in a proportion of recipients thereby increasing the opportunities for the induction of specific unresponsiveness to donor alloantigens in the future.

未来的挑战是，对移植患者的免疫系统进行良好的监测，应用个体化的免疫抑制方案，从而增加诱导针对供体同种抗原特异性免疫无反应性的机会。

Get high purity DCs by Cultured plastic-adherent monocytes isolated from healthy human peripheral blood with GM-CSF and IL-4 for 7 days. To observe the morphology of DCs by inverted phase contrast microscope ,electron microscope and laser confocal microscope. Analyse phenotype of DCs with flow cytometry. Investigate the endocytosis ability of DCs as a group by Horseradish peroxidase endocytosis assay. To appraise allogeneic mixed lymphocytes reaction of DCs by MTT reduction assay. Analyse the levels of IL-12 and TNF in liquids of cultured medium by ELISA and MTT reduction assay respectively. Soluble antigens of HCCs was obtained by 3 freeze-and-thaw cycles. Biological characteristics of HC soluble antigens pulsed DCs were monitored by flow cytometry. According to MTT reduction assay estimated the cell proliferation of self lymphocytes activated by HC antigens pulsed DCs. Get high purity BCG HSP 70 protein by SDS-PAGE electrophoresis and determined its biological activity with ELISA. Analyse phenotype of antigen pulsed DCs primed by BCG HSP70 with flow cytometry. By MTT reduction assay estimated the cell proliferation of self lymphocytes and the MLR of DC based vaccine. Analyse expression of HLA-DR molecule on surface of HCC lines. The IFN-γ mRNA in lymphocytes after actived by DC vaccine and the Fas-L expression on DC and DC vaccine primed lymphocytes were detected by in situ hybridization and flow cytometry respectively. Specific cytotoxity lysis of T lymphocytes and nonspecific inhibition of liquids in culture medium against HCC lines were also tested. Detect expression of hAFP on four HCC lines with Cell-ELISA. Induce apoptosis of HCCs with actinomycin-D. Interaction of DCs and apoptotic cells was observed under transmission electron microscope. Growth inhibition test of DC against HCC lines was also performed. Establish the nude mouse model bearing human HC xenografts and indentify the characteristic of tumour by histochemistry and immunohistochemistry techniques. Prevent and treat transplanted human HC on nude mouse with Freezing and anabiotic HC specific lymphocytes.

用GM-CSF和IL-4从健康人外周血诱导DC；分别用倒置相差显微镜、电子显微镜及激光共聚焦显微镜观察DC形态；流式细胞术检测DC表型；HRP吞噬实验测定DC的群体内吞能力；MTT法检测同种异体混合淋巴细胞反应；ELISA法和MTT法分别测定DC培养上清液中IL-12和TNF水平；冻融法制备肝癌细胞可溶性抗原；流式细胞术检测负载肝癌可溶性抗原后DC的生物学特性；MTT法检测DC负载肝癌抗原后对自身淋巴细胞增殖的影响；SDS-PAGE制备电泳纯化BCG HSP70并鉴定纯度，ELISA测定活性；流式细胞术检测负载抗原DC经BCGHSP 70活化后的表型；MTT法检测肝癌DC疫苗对自身淋巴细胞增殖的影响和混合淋巴细胞反应；流式细胞术检测肝癌细胞表面HLA-DR表达；MTT法检测肝癌DC疫苗对自身淋巴细胞的活化；原位杂交法检测肝癌DC疫苗活化后的淋巴细胞IFN-γmRNA表达；流式细胞术检测DC和肝癌DC疫苗活化后淋巴细胞表面Fas-L；MTT法分别检测肝癌DC疫苗活化的淋巴细胞和其培养上清对肝癌细胞的特异性杀伤和非特异性抑制作用；Cell-ELISA检测人肝癌细胞hAFP表达；MTT法检测负载AFP表位肽和凋亡肝癌细胞DC对自身淋巴细胞增殖的影响；ELISA法和MTT法分别测定活化后淋巴细胞培养上清中TNF和IL-12水平；肝癌细胞凋亡的诱导和检测；DC吞噬凋亡肝癌细胞后的电子显微镜观察；DC对肝癌细胞的生长抑制试验；人肝癌裸鼠皮下移植瘤动物模型的建立及其组织学和免疫组织化学鉴定；DC及肝癌特异性淋巴细胞预防和治疗人肝癌裸鼠皮下移植瘤；冻存和复苏后的肝癌特异性淋巴细胞预防和治疗人肝癌裸鼠皮下移植瘤。

But the positivity of CAg only occurs in using its same system.

而CAg仅在用同种抗原制成的抗体系统中被检出。

Pioneering work by Cohen and coworkers about T cell vaccination in the experimental autoimmune disease, has showed that the establishment of immune response against T cell vaccine, such as anti-idiotype T cells or anti -idiotype antibody, by the way of the upregulation of immune networks, and subsequently functional depression of autoimmune to self-antigen were made by vaccining mice or rate with the attenuated autoreactive T cells .

从研究TCV在防治自身免疫性疾病中的作用机制表明，人为的TCV免疫，建立了拮抗T细胞的免疫应答，使免疫网络产生上调作用，抑制了原有的或即将出现的相关T细胞的功能，由此推测，是否能够把同种反应性T细胞作为TCV，来建立抗同种免疫反应的内环境，诱导抗原特异性的同种免疫耐受或免疫低反应性。

The experiments may contribute not only to investigating the mechanism of interaction between ldiotype and anti -idiotype T cells by which immune network are up-regulated, but also to analysing the suppressive effect of anti -idiotypic T cell or antibodies against the antigens on the activated T cells in the allo-responsiveness.

本课题选用小鼠耳后心肌移植模型，用同种抗原特异的活化T淋巴细胞免疫同系小鼠的方法，诱导免疫小鼠同种心肌移植物存活时间的延长，以此探讨免疫网络中独特型-抗独特型相互作用机理，着重分析在同种抗原诱导的免疫应答中，抗独特型T细胞和抗活化T淋巴细胞抗原抗体对同种免疫反应的抑制作用。

Allogeneic and syngeneic fresh bone, autolyzed antigen-extracted bone, bone matrix gelatin, demineralized bone matrix were implanted into the muscle pouch of mice, at different times after implantation, the immunological, histological and alkaline phosphatase assay were conducted. The results revealed that all four kinds of allogeneic implants activated specific cellular and humoral immune responses, most notably in fresh bone group, the AAA, BMG and DBM inhibited the proliferation of the lymphocytes in vitro and BMG had the most powerful inhibiting action, allogeneic AAA, BMG and DBM might induce heterotopic osteogenesis in vivo, however, there were obvious difference in ALP and histomorphometry between allografts and isografts.

在小鼠肌肉内植入同种异体或同系新鲜骨、自消化抗原去除骨、骨基质明胶、脱钙骨基质，术后免疫学、碱性磷酸酶、组织学检查发现：4种同种异体植入物均可引发特异性细胞免疫反应和体液免疫反应，其中以新鲜骨移植引发的免疫反应最为显著；自消化抗原去除骨、骨基质明胶、脱钙骨基质在体外具有抑制淋巴细胞增殖的作用，骨基质明胶对淋巴细胞增殖的抑制作用最显著；同种异体与同系4种植入物在体内成骨活性有显著差异；自消化抗原去除骨、骨基质明胶、脱钙骨基质均有异位诱导成骨活性，其中骨基质明胶骨诱导活性最佳。

With the establishment of animal models of aortic homograft trans-plantation,using immunohistochemical staining,the differ-ence of the expression of MHCⅠantigen and MHCⅡanti-gen was detected between fresh aortic homografts and cryop-reserved aortic homografts.

建立大鼠同种异体主动脉移植模型，采用免疫组织化学实验研究新鲜主动脉和低温保存的主动脉同种异体移植后MHCⅠ类抗原和MHCⅡ类抗原表达的区别。

与同种抗原相关的网络解释 [注：此内容来源于网络，仅供参考]

concomitant immunity：伴随免疫[机体内存在某一抗原时对再侵入的同种抗原具有免疫力]

concerted feedback inhibition 协同反馈抑制 | concomitant immunity 伴随免疫[机体内存在某一抗原时对再侵入的同种抗原具有免疫力] | concurrent inhibition 并发抑制

concomitant immunity：伴随免疫[机体内存在某一抗原时对再侵渗入渗出的同种抗原具有免疫力]

cohesive end 粘端,粘性末端 | concomitant immunity 伴随免疫[机体内存在某一抗原时对再侵渗入渗出的同种抗原具有免疫力] | coating antigen 包被抗原

antigen, heterophile：异抗原

"群抗原","antigen, group" | "异抗原","antigen, heterophile" | "同种抗原","antigen, homologous"

isoantibody：同种抗体 同族抗体

isoanthricin 异峨参英 | isoantibody 同种抗体 同族抗体 | isoantigen 同种抗原 同族抗原

isoantigen：同种抗原

isoantibody 同种抗体 | isoantibody 同族抗体 | isoantigen 同种抗原

isoantigen：同种抗原 同族抗原

isoantibody 同种抗体 同族抗体 | isoantigen 同种抗原 同族抗原 | isoapiole 异芹菜脑

isoantigen; alloantigen：同种抗原

同种抗血清 alloantiserum; | 同种抗原 isoantigen; alloantigen; | 同种抗原抗血清 monoerg;

Allogenic antigen：同种异型抗原

3.同种异型抗原(allogenic antigen)指同一种属不同个体间所存在的抗原,亦称同种抗原或同种异体抗原. 常见的人类同种异型抗原有血型(红细胞)抗原和主要组织相容性抗原(人主要为HLA). 血型抗原有40余种抗原系统,主要有ABO系统和Rh系统.

Allogenic antigen：同种异型抗原,同种异体抗原

allodiplomonosome异源二倍单体 | allogenic antigen同种异型抗原,同种异体抗原 | allograft同种异体移植

isoimmunization; homologous immunization; alloimmunity：同种免疫

同种抗原抗血清 monoerg; | 同种免疫 isoimmunization; homologous immunization; alloimmunity; | 同种凝集 isoagglutination;