合成酶

基本解释 (translations)

synthetase  ·  synase

与合成酶相关的网络例句 [注：此内容来源于网络，仅供参考]

Antifolate Alimta derived from pyrrolo[2,3-d]pyrimidine is a multitargeted antitumor agent, it can inhibit at least five major folate-dependent enzymes: thymidylate synthase, dihydrofolate reductase, glycinamide ribonucleo -tide formyltransferase, aminoimidazole ribonucleotide formyl transferase and C-1 tetrahydrofolate synthetase(C1-S).

吡咯并[2，3-d]嘧啶类叶酸拮抗剂Alimta是一种多靶向的抗癌药物，它能抑制至少五种叶酸依赖性酶：胸苷合成酶、二氢叶酸还原酶、叶酰多聚谷氨酸合成酶、甘氨酰胺核糖核苷酸转甲酰酶及C1-四氢叶酸合成酶(C1-S)。。

Four different catechin content cultivars were selected from our tea germplasm appraisal database to assay the gene expression level of the seven genes, flavonol synthase, dihydroflavonol-4-reductase, leucoanthocyanidin reductase, anthocyanidin synthase, etc, which were involved in the flavonoids biosynthesis. The result showed that, the DFR and LAR transcripts were expressed increased with the increasing of tea catechin contents. Nevertheless, the others did not show this tendency clearly.

利用半定量PCR技术检测总儿茶素含量不同的4个茶树品种中与类黄酮合成相关的黄酮醇合成酶、二氢黄酮醇－4-还原酶、无色花色素还原酶、花色素合成酶等7个基因的表达情况，结果表明DFR和LAR基因的表达量与茶树中总儿茶素含量呈一定的相关性，而其他基因则与其相关性不大。

However, the first one enzyme 1-deoxy-D-xylulose 5-phosphate synthase gene and the second one enzyme 1-deoxy-D-xylulose 5-phosphate reductoisomerase gene in MEP pathway had been reported and expressed in the latex of rubber tree, indicating that MEP pathway may be involved in rubber biosynthesis.4 - hydroxy -3 - methyl -2 -- butenyl -4 - phosphate reductaseis the last enzyme that catalytic 4 - hydroxy -3 - methyl -(2E)- butenyl -4 - phosphate to generate isopentenyl pyrophosphate.

然而已有报道MEP途径中第1个酶1-脱氧-D-木酮糖-5-磷酸合成酶（1-deoxy-D-xylulose 5-phosphate synthase，DXS）基因和第2个酶1-脱氧-D-木酮糖-5-磷酸还原酶（1-deoxy-D-xylulose 5-phosphate reductoisomerase ，DXR）基因在橡胶树胶乳中的表达，这表明MEP途径可能参与橡胶的生物合成。4-羟基-3-甲基-2--丁烯基-4-磷酸还原酶（4-hydroxy -3-methyl-2--butenyl-4-diphosphate reductase，HDR）是异戊烯基焦磷酸合成途径之一甲基赤藓糖磷酸（methylerythritol phosphate，MEP）途径中的最后一个酶，催化4-羟基-3-甲基-(2E)-丁烯基-4-磷酸生成异戊烯基焦磷酸。

The effects of situ hybirdization study show that the expression of NO-i increases evidently in the cytolymph of bone. It proves that GSL can obviously increase the content of NO-i and promote the synthesis of bone and secretion of iNOS.

组化及原位杂交研究结果显示，在软骨细胞的胞浆中，NO合成酶的表达显著增加，表明骨疏灵能明显增加NO合成酶的含量，并能促进成骨细胞合成和分泌NO合成酶。

In this review, the biosynthetic pathway of ginsenosides was introduced and the research progress on enzymes related to ginsenoside biosynthesis , such as 3-hydroxy-3-methyl-glutaryl-CoA reductase, geranyl pyrophosphate synthase, farnesyl pyrophosphate synthase, was summarized in detail.

本文综述了人参皂苷的生物合成途径，并介绍了3-羟基-3-甲基戊二酸CoA还原酶、牻牛儿基二磷酸合成酶、法尼基二磷酸合成酶等人参皂苷合成途径相关酶的研究进展。

Glioma is still one of refractory disease in the neurosurgical field; the development of new primary and adjuvant treatment is vital. Recently, the gene therapy of glioma is developed rapidly and there are many methods about the gene therapy that include: suicide gene therapy, immunologic gene therapy, drug resistangce gene therapy, angiostatin gene therapy and so on. The sucide gene therapy is the most potential approach of antitumer, these nonmammalian genes encode enzyme that convert nontoxic prodrugs into highly toxic metablites. Cells transfected with suicide genes are targeted for specific negative selection, witch can be induced by administrtion of the corresponding produg. Among the enzyme/produg combinations, two of the best characterized system are herpes simplex virus thymidine kinase /ganciclovir and Escherichia coli cytosine deaminase /5-flourocytosine (5-FC). The formor can convert the antiviral nucleoside analogs acyclovir , ganciclovir to their nucleoside monophosphate derivatives, the monophosphate forms are subsequently phosphorylated by endogenus cellular kinases to triphosphates, these molecules are potent inhibitors of DNA synthesis.

近年来脑胶质瘤的基因治疗发展迅速，应运而生的方法有自杀基因、免疫基因、多药耐药基因以及抗血管生成基因等，其中自杀基因被认为是最有前景的基因治疗方法，它又称病毒介导的酶／药物前体疗法，是利用转基因技术将哺乳动物细胞中所不含有的自杀基因转入到哺乳动物肿瘤细胞中，该基因表达的产物可将无毒的药物前体转化为毒性药物，从而选择性杀伤该肿瘤细胞，常用的自杀基因有单纯疱疹病毒-胸苷激酶基因和大肠杆菌胞嘧啶脱氨酶基因，前者催化无毒性抗病毒核苷类似物如丙氧鸟苷、无环鸟苷等成为单磷酸核苷衍生物，然后在内源性细胞激酶作用下转化为具有明显毒性的三磷酸核苷，作为DNA合成链的终止剂和DNA合成酶的抑制剂，干扰细胞DNA的合成；后者编码的胞嘧啶脱氨酶可催化5-氟胞嘧啶（5-FC）脱氨成为5-氟尿嘧啶（5-FU），然后代谢为有毒性的5-氟尿嘧啶-5′三磷酸（5-FUTP）和5-氟-2′脱氧尿嘧啶-5′磷酸（5-FdUTP），5-FUTP通过与UTP竞争性结合而抑制mRNA和tRNA的合成，5-FdUTP则作用于胸苷合成酶，导致TMP衰竭而阻止DNA的合成，最终诱导肿瘤细胞凋亡。

Escherichia coli and many other microoganism synthesize aromatic amino acids through the condensation reaction between phospho enolpyruvate and erythro.

ppsA和tktA是芳香族氨基酸生物合成中心途径的两个关键酶基因，在大肠杆菌中，ppsA基因编码磷酸烯醇式丙酮酸合成酶A ，该酶催化丙酮酸合成磷酸烯醇式丙酮酸；tktA基因编码转酮酶A ，该酶在磷酸戊糖途径中生成 4 磷酸赤藓糖起主要作用。

In plant,the enzymes of RFO,such as galactinol synthase,myo inositol-1-phosphate synthase, raffinose synthase and stachyose synthase,are linked with the RFO pathw.

寡糖代谢是一个复杂的调控体系，其中肌醇-1-磷酸合成酶、肌醇半乳糖苷合成酶、蔗糖合成酶、棉子糖合成酶、水苏糖合成酶和毛蕊花糖合成酶等参与了棉子糖系列寡糖的生物合成过程。

Pharmacology function】Huang An the AN oxygen Mi Ding be in the Huang An medicine to suppress the germ a very strong kind of the function to synthesize anti-virus medicine, because of it with for germ to synthesize folic acid demand of to ammonia Ji the benzene be sour to have likeness on the structure, exchange with PABA to contend for two hydrogen folic acids to synthesize Mao, bar the germ synthesize two hydrogen folic acids to synthesize Mao, bar the germ synthesize two hydrogen folic acids, end influence nucleic acid protein of synthesize, repress thus germ of growth breed, to variety E-and E+very strongly repress a function.

磺胺间甲氧嘧啶是磺胺类药物中抑菌作用极强的一种合成抗菌药物，因其与细菌合成叶酸时所需要的对氨基苯酸在结构上具有相似性，与PABA兑争二氢叶酸合成酶，阻碍细菌合成二氢叶酸合成酶，阻碍细菌合成二氢叶酸，最终影响核酸蛋白质的合成，从而抑制细菌的生长繁殖，对多种E-及E+有很强的抑制作用。

Huang-hua' pear fruit was a typical climacteric fruit after harvest, and the fruit senescence-related factors, such as LOX activity, 02" content, AOS activity, ACC synthase activity, ACC content, ACC oxidase activity and ethylene production, changed with peaks at 20 "C. The activities of LOX, AOS, ACC synthase, ACC oxidase and the accumulation of O2 ", ACC content and ethylene synthesis were inhibited when stored at 1癈. And the severity of flesh floss and fruit decay was lightened. Low temperature combined with polyethylene film bag packing (PEF1 and PEF2) could further decrease the rate of weight loss, flesh floss, and fruit decay and keep preferable freshness. When PEF1 and PEF2 packing fruits were transferred to shelf life at 20 "C after storage at 1癈. The activities of LOX, AOS, ACC synthase, ACC oxidase could be suppressed and the accumulation of 02 , ACC content and ethylene production were slowed down to a certain extent, especially during the shelf life after 60 d storage. PEF1 and PEF2 packing fruit could maintain higher firmness as well, and the effects became more distinct along with the storage period, there existed no significant difference between PEF1 and PEF2 treatments.

试验结果表明，在20℃下，LOX活性、O2-水平、AOS活性、ACC合成酶活性、ACC含量、ACC氧化酶活性及乙烯的生成，均呈峰形变化；1℃处理可抑制LOX、AOS、ACC合成酶、ACC氧化酶的活性和O2-、ACC的积累，抑制贮藏果实的乙烯合成，减轻果肉发绵和果实腐烂。1℃下贮藏的果实，若结合不同聚乙烯薄膜袋(PEF1和PEF2)小包装，可以进一步降低果肉发绵率和果实腐烂率，保持果实新鲜度；当果实经过一段时间贮藏后，转移到20℃下，在货架期间，PEF1和PEF2对果实成熟衰老各个相关因子均有不同程度的抑制效应，主要表现在贮藏60d后的货架期间，同时维持较高的果实硬度，对硬度的影响随着贮藏时间的延长愈加明显，PEF1和PEF2处理效果之间无显著差异。

与合成酶相关的网络解释 [注：此内容来源于网络，仅供参考]

antisynthetase autoantibody：抗合成酶自身抗体

31 antiretroviral therapy 抗逆转录病毒治疗 | 32 antisynthetase autoantibody 抗合成酶自身抗体 | 33 antisynthetase syndrome 抗合成酶综合征

endothelial nitric oxide synthase (eNOS) gene：醛固酮合成酶基因

蔗糖:sucrose | 醛固酮合成酶基因:endothelial nitric oxide synthase (eNOS) gene | 内皮型一氧化氮合酶基因:aldosterone synthase gene

Human Endothelial nitric oxide synthase,eNOS ELISA Kit：人内皮型一氧化氮合成酶(eNOS)ELISA试剂盒

人胱天蛋白酶9(Casp-9)ELISA试剂盒 Human Ca... | 人内皮型一氧化氮合成酶(eNOS)ELISA试剂盒 Human Endothelial nitric oxide synthase,eNOS ELISA Kit | 人诱导型一氧化氮合成酶(iNOS)ELISA试剂盒 Human inducible n...

glutamine synthetase：谷氨酰胺合成酶

酶促反应通式可表示为:此类反应多数不可逆. 反应式中的Pi或PPi分别代表无机磷酸与焦磷酸. 反应中必须有ATP(或GTP等)参与. 常见的合成酶如丙酮酸羧化酶(pyruvate carboxylase)、谷氨酰胺合成酶(glutamine synthetase)、谷胱甘肽合成酶(glutathione synthetase)等.

glutamine synthetase：谷氨酸盐合成酶

Methylation 甲基化 | Glutamine synthetase 谷氨酸盐合成酶 | allosteric enzyme 变构酶

Nos：一氧化氮合成酶

0 一氧化氮合成酶(nos)测试盒型(t-nos、inos、cnos)三型同时出结果 25t 江苏 433.00 乳酸(ld)测试盒 血清、组织等 50t 江苏 333.00 乳酸(ld)测试盒全血(紫外分光光度法) 50t 江苏 400.00 乳酸(ld)测试盒全血(可见光分光光度法) 50t 江苏 400.00 乳酸脱氢酶(ldh)测试盒 100t 江苏 400.00 乳酸脱氢酶(ldh)测试盒 50t 江苏 217

synthetase：合成酶

synthesizer 合成仪 | synthetase 合成酶 | synthetic antigen 合成抗原

Chalcone synthase：查尔酮合成酶基因

查尔酮:Chalcone | 查尔酮合成酶基因:Chalcone synthase | 查尔酮合成酶:Chalcone synthase

isoflavone synthase：异黄酮合成酶

糖原合成酶激醇:Glycogen Synthase Kinase | 异黄酮合成酶:isoflavone synthase | Chalcone synthase的例句:

nitrogen monoxide synthetase：一氧化氮合成酶

一氧化氮合酶:nitrous oxide synthetase | 一氧化氮合成酶:nitrogen monoxide synthetase | 蔗糖磷酸合成酶基因:sucrose phosphate synthase gene