变异发生

基本解释 (translations)

mutagenesis

与变异发生相关的网络例句 [注：此内容来源于网络，仅供参考]

As showed above, we could draw the conclusion that H3 viruses could cause outbreaks or local epidemics in Shanghai for the immune of population to the new emerging antigenic drift was still unknown though there was strong immune barrier to the previous vaccine strain, H1 viruses also may caused epidemics as the population had a weak immune protection to the previous reference strains A/New Caledonia/20/99-like and part of the recent isolates were distingwishing from them and continued to evolute on the new reference strain, and H5N1 HPAI activities has expanded its geographical range thus increasing the size of the population at risk as the continuing emergence of human cases which give the virus an opportunity to evolve towards a fully transmissible pandemic strain. We should keep eyes on the human cases of avian influenza virus an its variation for the H5 isolates in Shanghai also has the possibility to infect human directly and the infection of H5, H9 viruses had previously occurred in the population especially in those contacting with animals.

综合上述分析结果，我们认为上海地区人群虽然对原有的H3亚型参考病毒株有较高的免疫保护，但H3亚型病毒HA已出现新的抗原漂移，人群现在对新变异株的保护水平尚未知，有可能在未来引起局限性暴发甚至地方性流行；人群对H1亚型流感病毒免疫保护水平低，同时H1亚型流感病毒株部分与原推荐疫苗株抗原性差别较大，并在现推荐疫苗株基础上继续变异，需警惕发生流行的可能性；H5N1亚型高致病性禽流感地域范围扩大，人间病例不断发生，存在演变成大流行株的威胁，上海市H5亚型禽流感病毒株存在跨宿主屏障感染人类的可能性，而且已发现人群尤其禽、畜类动物接触人群中存在H5、H9亚型流感病毒的既往感染，应警惕禽流感病毒的变异和人间病例的发生。

YMDD mutation: HBV YMDD mutation were developed in 12 lamivudine recipients, whereas the treated group had no incidence of HBV YMDD variation, there were significant difference between two groups (p=0.000). YMDD mutation resulted in increase of the mean HBVDNA levels (p=0.000), but no contribution to serum ALT diversification (p＞0.05). 2. Precore nt1896 mutation: Precore nt1896 mutation incidence had no difference between lamivudine recipients and objects who received combination therapy of Kidney-invigorating Granule and Marine Injection, and patients of HBeAg negative and HBeAg positive had a close incidence of precore mutation as well as. Precore nt1896 mutation had no influence on serum ALT level. The occurrence of precore nt1896 mutation contributed to serum HBVDNA load increased and worse response of HBVDNA extenuation. 3. HBV genotype: The baseline of serum HBVDNA gradually increase in turn of genotype B, genotype C and genotype B/C. Genotype B seemed to obtain higher rate of serum HBVDNA loss and HBeAg/anti-HBe seroconversion after combination therapy of Kidney-invigorating Granule and Marine Injection, differencing with lamivudine therapy.

疗效相关因素研究：1YMDD变异：对照组有12例检出YMDD变异，治疗组无1例检出，两组比较有显著性差异（P=0.000）；发生YMDD变异者血清HBVDNA和ALT水平均有所升高，HBVDNA平均水平高于非变异者（P=0.000）；血清ALT与非变异者无明显差异（P＞0.05）。2前C区nt1896变异：前C区nt1896变异发生率在治疗组和对照组以及HBeAg阴性和HBeAg阳性患者之间均无明显差异（P＞0.05）；1896c变异对血清ALT水平无明显影响；治疗组发生1896c变异者，其HBVDNA平均水平较之未变异者明显升高（P＜0.05），治疗后HBVDNA下降幅度明显低于未发生1896c变异者（P=0.000）。3HBV基因型：血清HBVDNA基础水平在B、C、B/C混合型间存在明显差异（P＜0.05），按B型、C型、B/C混合型依次升高；治疗组HBVDNA阴转率、HBeAg/抗-HBe血清转换率，B型似乎高于C型和B/C混合型，但无统计学意义（P＞0.05）；对照组HBVDNA阴转、HBeAg/抗-HBe改变在B、C、B/C混合型间无明显差异（P＞0.05）。

That is why we are interested in genetic variation.

这就是为什么我们对遗传变异发生兴趣。

The present thesis is intended to approach several aspects on the mechanism of plant somaclonal variation by cytological methods.

本论文拟从细胞学的角度探讨植物体细胞无性系变异发生机理方面的几个根本问题。

OBJECTIVE ①To compare the sequences of the ribosomal rDNA-ITS2, 28S-D3 and mitochondrial mtDNA-COII in the different origins of Anopheles minimus for detecting the intra-and inter-specific variation of the sibling species of the Minimus Complex;②To reconstruct phylogenetic trees of the Minimus Complex and Myzomyia Series for determining the position of An. minimus A and C;③To establish specific methods for differentiation of two sibling species, An. minimus A and An. minimus C, of the Minimus Complex.

中文题名微小按蚊种群变异与分子鉴别研究副题名外文题名论文作者周水森导师汤林华研究员学科专业分子流行病学研究领域\研究方向学位级别博士学位授予单位中国预防医学科学院学位授予日期2002 论文页码总数98页关键词蚊微小按蚊馆藏号BSLW /2003 /R384 /3 目的①比较微小按蚊核糖体rDNA-ITS2、28S-D3基因和线粒体mtDNA-COII基因的序列差异，阐明微小按蚊复合体亲缘种种间和种内变异；②根据基因变异重建微小按蚊复合体及迈蚊系成员的种系发生关系，以确立微小按蚊亲缘种变异的种系地位；③建立微小按蚊复合体亲缘种A和C的分子鉴别方法。

At the same time, the relationship between genera Machilus and Persea was also discussed. The result of chloroplast DNA analysis indicated that C. philippinense was closer to Machilus than to Cinnamomum. There was no difference between C. philippinense, Machilus thunbergii, M.

上述3个叶绿体DNA片段的定序结果显示菲律宾樟较靠近桢楠属，在3个片段多达31处变异处可供辨识的位置上菲律宾樟与桢楠属植物序列之间没有任何变异，而两者与樟树有15处发生序列变异或插入缺失，与酪梨亦有14处发生变异或缺失。

With the growth of age, the ulnar variance tends to change dynamically.

2随着年龄的增长，尺骨变异发生动态变化。

Objective: To investigate genotype and drug resistance in HIV/AIDS infectors in Henan Province.

目的：检测研究河南省艾滋病病毒基因型耐药变异发生的情况。

It was thought that these variations took place at the stage of forming flower organ subregions, and could not be interpreted by "ABC model" for flower organ development, nor by the advanced "ABCD model" and "ABCDE model".

分析认为：韭兰的花形变异发生在花亚区的形成期，不能用花器官发育的&ABC模型&以及由&ABC模型&为基础发展而来的&ABCD模型&和&ABCDE模型&解释。

The published Kentucky bluegrass transformation system has many disadvantages including the diffculty of regeneration, high frequency of somaclonal, long-time transformation period and low efficiency of transformation.

现有的草地早熟禾遗传转化体系存在着植株再生困难、体细胞无性系变异发生频率高以及转化周期长、效率低等缺点，严重制约了早熟禾基因工程育种研究的发展。

与变异发生相关的网络解释 [注：此内容来源于网络，仅供参考]

Antigenic drift：抗原漂移

vRNP 复合体滞留在细胞核内不能向胞内转运" 4猪流感病毒的变异诱发猪流感病毒发生变异的主要机理有$%1&抗原漂移 (antigenic drift)$基因组自发的点突变引起小幅度的变异!

gene mutation：基因突變 基因突变

笫二节 基因突变 基因突变(gene mutation)简称突变,是变异的一种,指生物细胞遗传物质 DNA 分子结 构突然发生了稳定的可遗传的变化.它是生物进化的一个重要因素.一,细菌变异的类型 细菌的变异可分为非遗传性变异和遗传性变异.前者基因无改变,

Mutate：变异

因为,要把这些参数储存到hashmap里会是非常危险的一件事.根据Map的定义,当这个Map里的key发生改动,Map是不知道的.所以,当你执行了一次这个method之后,相关信息添加进了Map,然后参数发生变异(mutate),第二次调用的时候,

relative frequency：相对频数

他首先就若干物种详细地列举了构造的许多方面的 变异情况,并用数字计算出变异的相对频数(relative frequency). 他举出了甚至在 同一枝条上发生变异的十二种以上的性状,这些变异有时是由于年龄和发育的情况,有 时则没有可以归因的理由.

secular trend：长期趋势

④ 病原体变异.长期变异在一个相当长的时间内(通常为几年或几十年),疾病的发病率、死亡率、感染类型等发生显著的趋势性变化,这种现象称为长期变异(secular change),或长期趋势(secular trend).(三)地区分布疾病的发生往往受不同地区的自然环境和社会条件影响.因此,

unstable：不稳定型

变异血红素分为稳定型(stable)与不稳定型(unstable)两大类,中国附医团队研究的重点─变异血红素E(HbE)发生於第11对染色体β血红蛋白链基因的一种不稳定型变异血红素.

autogeny：自然发生

autogenous variation 可遗传的变异 | autogeny 自然发生 | autograft 自体组织移植片

epigenetic：后生的

Mintz的试验到目前仍然是独特的,它表明至少有些癌是能够由外遗传、后生的(epigenetic)改变发生的. 但是,毫无疑问大多数是在DNA水平上发生改变引起的. 要想研究瘤细胞群体的变异和选择,显然必须先研究变异.

genotypic variation：基因型变异

细菌的变异现象有两种类型:一种是遗传性变异,是细菌基因组发生改变导致的性状改变,又称基因型变异(genotypic variation),变异的性状可以稳定遗传给子代.

gene polymorphisms：基因多态性

与眼病发生发展有关的基因其实属于遗传变异,也就是基因组DNA序列发生了变化,在DNA水平上表现为基因多态性(gene Polymorphisms). 如此DNA序列的不同可影响人类的很多特性,特别是对疾病的易感性. 近年来,在DNA水平上发现了大量的遗传变异,