受体

基本解释 (translations)

accepter  ·  receptor  ·  ceptor  ·  receptors

与受体相关的网络例句 [注：此内容来源于网络，仅供参考]

The holding potential was -70mV.(2) By whole-cell voltage-clamp technique, after slices were preincubated with glycine receptor competitive antagonist alone or with GABA〓 receptor competitive antagonist alone or with GABA〓 receptor incompetitive antagonist alone or with GABA〓 receptor and glycine receptor competitive antagonists collaterally or with GABA〓 receptor incompetitive antagonist and glycine receptor competitive antagonist collaterally, the effects of 100μM propofol on EPSCs of the CA1 neurons of the rat hippocampus were investigated. The holding potential was -70mV.

2应用全细胞膜片钳技术，观察100M丙泊酚对单纯用甘氨酸受体竞争性拮抗剂预孵、单纯用GABA〓受体竞争性拮抗剂预孵、单纯用GABA〓受体非竞争性拮抗剂预孵、合用GABA〓受体和甘氨酸受体竞争性拮抗剂预孵以及合用GABA〓受体非竞争性拮抗剂和甘氨酸受体竞争性拮抗剂预孵的大鼠海马脑片CA1区电刺激诱发的EPSC的影响。

Glycine receptor competitive antagonist partially reversed the effects of propofol. When slices were preincubated with GABA〓 receptor and glycine receptor competitive antagonists collaterally or preincubated with GABA〓 receptor incompetitive antagonist and glycine receptor competitive antagonist collaterally, 100μM propofol still decreased the amplitude of EPSCs.

2在膜钳制电压为-70mV条件下，100M丙泊酚明显降低合用GABA〓受体和甘氨酸受体竞争性拮抗剂预孵的大鼠海马脑片CA1区电刺激诱发的EPSC幅值，下降程度小于单纯甘氨酸受体竞争性拮抗剂预孵组，大于单纯GABA〓受体竞争性拮抗剂预孵组；而且，100M丙泊酚更是明显降低合用GABA〓受体非竞争性拮抗剂和甘氨酸受体竞争性拮抗剂预孵的大鼠海马脑片CA1区电刺激诱发的EPSC幅值，下降程度甚至大于单纯甘氨酸受体竞争性拮抗剂预孵组。

The affected chicks acquired the morphine conditioned place preference more quickly, and maintained it much longer. Experiment 3 showed that during E5-8, injecting delta receptor antagonist naltrindole reversed the learning and memory impairment caused by morphine while delta receptor agonist DPDPE impaired learning and partial memory function. On the other hand, mu opioid receptors had little effect. As for E17-20, given naloxonazine can reverse the increases of susceptibility to morphine, and the mu receptor agonist DAGO cause the increases of susceptibility to morphine. Delta receptors have no effect.

研究结果发现：经过对鸡胚发育不同时间段的吗啡给药，胚胎期发育E5-8阶段给予吗啡的小鸡学习记忆受损最为严重，表现为学习和记忆功能的严重下降；而E17-20时段吗啡给药的小鸡更容易获得吗啡CPP且保持时间更长。E5-8阶段给予delta受体拮抗剂natrindole能够翻转吗啡对学习和记忆的损害作用，并且给予delta受体激动剂DPDPE也损害学习和部分记忆功能，mu受体作用不大。E17-20阶段拮抗mu受体能够抑制成瘾易感性的增加，激动mu受体可以增加小鸡的成瘾易感性，delta受体没有明显作用。

In ovary, PNA receptors appeared in the oocyte cytoplasm of second phases of oogenesis; the positive granules gradually increased from third to forth phases, and they exhibit a maximum expression before vitellogennic stage in cytoplasm of oocyte; from vitellogennic stage to chorionation stage, the positive granules gradually reduced. Binding sites on follicle cells were changed with their morphological variation in every stage of oogenesis.The staged and specific expression of oncogene c-kit, the tyrosine-kinase receptor, is closely related with gametogenesis.

2在中华蚱蜢卵子发生的早期，PNA受体是由卵母细胞自身合成；在卵黄发生前的准备时期，卵母细胞质中的PNA受体一部分来源于自身合成，另一部分则来源于滤泡细胞，而糖复合物的大量出现可能直接与卵黄发生有关；卵黄发生期PNA受体的减少可能是在卵黄物质形成中部分发生了修饰；卵黄和卵壳的相继形成过程中，阳性反应的出现说明PNA受体参与了卵黄膜及卵壳的形成，而这些受体物质是由滤泡细胞分泌的。

Protease treatment of the plasma membranes could abolish the binding but NaIO_4 and glycosidase could not, indicating that nsLTP144 bound to plasma membranes protein without carbohydrate moiety. Using the homobifunctional cross-linking regent bissuberate (BS~3) and rice plasma membranes incubated with ~(125)I-Trx-nsLTP144, we identified, after SDS-polyacrylamide gel electrophoresis and autoradiography, a putative protein receptor on the rice plasma membranes with the molecular mass around 60 kDa. NsLTP144 can not trigger extracelluar alkalization in arabidopsis, but can abolish the extracellular alkalization effect of phytopathogen elicitor cryptogein, suggesting that cryptogein and nsLTP144 may bind to the same membrane protein. In vitro pull-down assay showed that nsLTP144 interacted with OsCaM1, a possible extracellular calmodulin, implying that nsLTP144 and OsCaM1 could function in the same signal transduction pathway. These results shed light on revealing the roles of nsLTP in vivo and make it promising to finally characterize the plasma membranes receptor of nsLTP.

发现~(125)I-Trx-nsLTP144、~(125)I-Trx-nsLTP110与水稻细胞质膜均具有特异性结合，而且结合是饱和性的、可被竞争的，符合配体-受体结合的典型特征，同时用于对照实验的蛋白质~(125)I-Thioredoxin没有此特性，表明水稻细胞质膜上存在nsLTP的受体；利用可氧化糖基的NaIO_4和水解糖基的N\'-糖苷酶F处理水稻细胞质膜，再进行结合实验，结合活性几乎不受影响；而利用胰蛋白酶处理细胞膜则使得结合能力几乎完全丧失，表明其受体为没有经过糖基化修饰的蛋白质；利用交联剂BS~3交联配体一受体后，再进行SDS-PAGE分离和放射自显影，结果显示水稻细胞质膜上的nsLTP受体中有一个60kDa的蛋白质可以与nsLTP144发生特异性的结合，可能是其受体；细胞外碱化实验表明，nsLTP144不能促使拟南芥原生质体细胞培养液的细胞外碱化反应，却能猝灭来自植物病原菌的激发子Cryptogein刺激拟南芥原生质体产生的细胞外碱化反应，表明nsLTP和Cryptogein结合细胞膜上相同的位点，保护了植物细胞免受Cryptogein导致的细胞程序性死亡，并诱导系统获得性抗性的产生；体外Pull-down实验表明，nsLTP144和水稻的OsCaM1具有相互作用，暗示了nsLTP144和OsCaM1可能同在一个信号通路上起作用。

We have identified 1452 GPCRs in the X.tropicalis genome.(2) Phylogenetic analyses classified these receptors into seven families, consisting of Glutamate,Rhodopsin,Adhesion,Frizzled,Secretin,Taste 2 and Vomeronasal 1.(3) X.tropicalis shares a more similar repertoire of GPCRs with mammals than it does with fish.

2严格的系统发生学分析将热带爪蟾G蛋白偶联受体分成了谷氨酸盐受体类，视紫红质类，粘着蛋白类，卷曲蛋白类，味觉2受体类，分泌素受体类和犁鼻骨1受体类这七个受体家族。

E. , ACTH antagonizes the analgesia mediated byμand δ opioid receptors, but notκreceptor;(2) The antagonizing effect of ACTH on opioid analgesia is proposed to be mediated by ACTH receptors, although the latter has not been characterized;(3) A contradictory interaction on intracellular cAMP content may constitute one of the postreceptor mechanisms underlying ACTH antagonism of opioid analgesia;(4) Another proposed mechanism of the anti-opioid effect of ACTH is that ACTH can modulate opioid-induced suppression of calcium influx;(5) ACTH has been shown to induce Fos protein expression in selected areas of the rat brain including the nuclei involved in pain regulation as well as the ependyma of the third ventricle and the aqueduct.

根据以上实验结果，本论文首次提出以下论点：（1）ACTH在脊髓水平对抗阿片镇痛具有受体选择性，即ACTH可对抗μ受体和δ受体介导的镇痛，不对抗κ受体所介导的镇痛；（2）由于ACTH与阿片μ受体的肽类配体的结合位点仅有很低的亲和力，与μ受体的非肽类配体的结合位点以及δ受体无亲和力，推测ACTH是通过中枢内的ACTH受体介导发挥抗阿片效应的；（3）ACTH抗阿片作用的受体后作用机制之一是在cAMP信使通路水平与阿片发生相互作用；（4）ACTH抗阿片作用的另一受体后机制是在〓水平影响阿片的效应；（5）通过Fos蛋白的诱导揭示：ACTH可以作用于脑内多个核团，其中包括许多与痛觉调制有关的核团，推测ACTH可能通过激活这些核团的神经元而发挥其中枢效应。

The extremities were titanic, and there was no response to touch stimulations.Our results suggested that Pentobarbital sodium inhibited neuronal firing through GABA_A receptors, therefore the local field potentials and neural firing rates were inhibited; Urethane acted on many kinds of receptors including inhibitory and excitory ones, so the local field potentials did not change significantly; however, because of the multiform receptors on the neurons, the changing of firing rates to different neurons were not the same; Ketamine mainly acted on the NMDA receptors, therefore the local field potentials and neural firing rates were enhanced, and most neural firing rates would be increased.

从这三种麻醉剂的底层作用机制来看，戊巴比妥钠通过作用于GABAA受体对神经细胞发挥抑制性作用，因此表现为场电位和神经元放电的降低；氨基甲酸乙酯同时作用于多种受体通道，既有兴奋性受体，也有抑制性受体，因此，对场电位的影响不大，但对单个神经元来说，每个神经细胞上的受体通道分布差异较大，因此，单个神经元的放电频率变化会有所不同；盐酸氯胺酮主要作用于兴奋性的NMDA受体，故整体场电位活性增加，多数神经元的放电频率也会有所升高。

The anatomical localizations indicate that Al receptor and Dl receptor coexist in strionigro-strioentopeduncular neurons, and A2a receptor and D2 receptor coexist in striopallidals neurons. The heteromeric complexes of Al/D1、A2a/D2 receptor provided the molecular basis for the functional interactions of Al/Di and A2a/D2 receptor.

腺苷A1受体和多巴胺D1受体以及腺苷A2a受体和多巴胺D2受体分别共存於基底神经节中纹状体向黑质和脚内核投射的神经元以及纹状体向苍白球投射的神经元内。A1/D1、A2a/D2受体形成受体异聚复合体构成了受体一受体之间相互作用的分子基础。

Erve growth factor can combine with its" receptor (one of tyrosine protein kinase receptor coded by proto - oncogene tyrosine kinase, TrkA), Causing the molecule of receptors to gather on the cell surface, and the tyrosine protein in cytoplasmic domain may be activated, three tyrosine base in the kinase domain of its" receptor and two tyrosine base at other domain be phosphated, thus, phosphated tyrosine receptor kinase became the bracket which absorb all kinds of connective proteins and kinases.

GF与其酪氨酸受体激酶受体(由原癌基因trk编码的一种酪氨酸蛋白激酶受体，TrkA)相结合，引起受体分子在细胞表面发生二聚体化，然后受体细胞内结构上酪氨酸活性被激活，使受体自身结构中位于激酶结构域的三个酪氨酸残基及在此结构域外的两个酪氨酸残基发生自身磷酸化，这样，磷酸化的酪氨酸受体激酶A便成为吸收各种连接蛋白质和酶的支架。

与受体相关的网络解释 [注：此内容来源于网络，仅供参考]

Histamine Receptors：组胺受体

3.胃酸分泌过多 盐酸是胃液的主要成分,由壁细胞分泌,受神经,体液调节,已知壁细胞膜含有3种受体,即组胺受体(histamine receptors),胆碱能受体(cholinergic receptors)和胃泌素受体(gastrin receptors),分别接受组胺,乙酰胆碱和胃泌素的激活,

opiate receptor：阿片受体

4.中枢内递质的受体 中枢递质种类复杂,因此相应的受体也多,除胆碱能N型和M型受体、肾上腺素能α和β受体外,还有多巴胺受体、5-羟色胺受体、兴奋性氨基酸受体、γ-氨基丁酸受体、甘氨酸受体,阿片受体(opiate receptor)等.

orphan receptor：孤独受体,孤儿受体[目前尚未找到配体的受体]

orotidine 乳清苷 | orphan receptor 孤独受体,孤儿受体[目前尚未找到配体的受体] | orphon 孤独基因[由成串重复序列衍生的单个分立基因]

receptor binding site：受体结合部位

receptor-associated molecule 受体相关分子 | receptor binding site 受体结合部位 | receptor clustering 受体群集,受体聚集,受体成簇

cholinergic receptor：胆碱受体

胆碱受体(cholinergic receptor)是能选择性地与ACh 结合的受体,又可分为M 胆碱受体和N 胆碱受体. ...

adrenoceptor agonists：肾上腺素受体激动药

肾上腺素受体激动药(adrenoceptor agonists)是一类能与肾上腺素受体结合并激动该受体,产生与肾上腺素能递质(去甲肾上腺素)作用相似的药物. 肾上腺素受体激动药的基本化学结构为β-苯乙胺,其中肾上腺素、去甲肾上腺素、异丙肾上腺素、多巴胺和多巴酚丁胺的化学结构含有儿茶酚,

cholinoceptor agonists：胆碱受体激动药

胆碱受体激动药(cholinoceptor agonists)可激动胆碱受体. 产生与乙酰胆碱类似的作用. 乙酰胆碱是中枢和外周神经系统的内源性神经递质,其主要释放部位在神经突触和神经效应器接头部位,主要作用为激动毒蕈碱型胆碱受体(M胆碱受体)和烟碱型胆碱受体(N胆碱受体). 前者医'学教育网搜集整理主要分布于副交感神经 ...

Muscarinic receptor：毒蕈碱受体

M-毒蕈碱受体(Muscarinic receptor)又称M型乙酰胆碱能受体,与β肾上腺能受体均为广泛分布于心肌组织的主要心肌受体. 被激活的受体偶联相应的G蛋白,通过改变心肌细胞内腺苷酸环化酶活性来发挥其生理作用. 在病理状态下,

Muscarinic receptor：毒蝇碱性受体,毒蕈碱性受体

muscarinic cholinergic receptor 毒蝇碱性胆碱能受体,毒蕈碱性胆碱能受体 | muscarinic receptor 毒蝇碱性受体,毒蕈碱性受体 | muscle fiber 肌纤维

muscarinic acetylcholine receptor：毒蝇碱性乙酰胆碱受体,毒蕈碱性乙酰胆碱受体

Muscarine 毒蝇碱,毒蕈碱 | muscarinic acetylcholine receptor 毒蝇碱性乙酰胆碱受体,毒蕈碱性乙酰胆碱受体 | muscarinic cholinergic receptor 毒蝇碱性胆碱能受体,毒蕈碱性胆碱能受体