- 更多网络例句与双胍相关的网络例句 [注:此内容来源于网络,仅供参考]
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Dr Gregg Fonarow, Eliot Corday Professor of Cardiovascular Medicine at UCLA and coauthor of this study, noted, Experimental studies suggest that metformin improves myocardial function via activation of a signaling mechanism (AMP-activated protein kinase) independent of antihyperglycemic effects.
另两位合作研究者,加州大学洛杉矶分校心血管内科教授Gregg Fonarow博士和Eliot Corday博士还提到:"实验室研究提示,二甲双胍改善心肌功能是通过激活了一种不同于降糖作用的信号机制(AMP-活化的蛋白激酶)"这些研究结果共同提示,二甲双胍可能具有心脏保护作用,这一作用是通过在分子水平增强心脏功能来实现的。
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FPG,FINS,TG,TC,LDL-C of Model group were increased,ISI were decreased . The expression of PAI-1mRNA of adipose tissues was increased significantly (.2)Compairing with model group,the berberine and taurine group and combine group could significantly increase insulin sensitivity, decrease the expression of PAI-1mRNA in epiploon adipose tissue. The parameters mentioned above in combine group was better than other groups.
与正常组比较,模型组体重增加,血清 FPG、FINS、TG、TC 、LDL-C 升高,ISI 降低,血清中 FFA 浓度增加,内脏脂肪细胞肥大,脂肪组织中 PAI-1 mRNA 表达显著增加;(2)与模型组比,联合组、黄连素组、牛磺酸组、二甲双胍组均出现 ISI 升高和 PAI-1mRNA 表达减少,二者的协同作用优于单独作用,并优于二甲双胍组。
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Design, Setting, and Participants Case-control study of 21 patients with type 2 diabetes (studied 2003-2005) compared with 21 age- and sex-matched controls (studied in 2001) in Montpellier, France.
研究设计及方法:将新近诊断的,或曾经使用过口服降糖药,现仅有饮食及锻炼治疗的2型糖尿病成年病人随机分组,并接受二甲双胍缓释片或速效二甲双胍双盲治疗24周。
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Postprandial contribution to glycemic instability was assessed by determining the postprandial increment of glucose leel aboe preprandial alues (mean postprandial incremental area under the cure ).
相反,使用2,000-mg二甲双胍缓释片的治疗组糖化血红蛋白水平有显著下降(–1.06%), 2,000mg二甲双胍缓释片治疗组与速效二甲双胍片治疗组比,糖化血红蛋白水平平均值相差–0.36% [98.4% CI –0.65 to –0.06]。
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(1)This three schemes mentioned above are effective for weight reduction, among them, the effect is best by using sibutramine and metformin together, which is second-best by using sibutramine simply and tertius by metformin.
①三种治疗方案对减肥均有疗效,其中西布曲明和二甲双胍联合治疗疗效最佳,单用西布曲明疗效次之,而单用二甲双胍疗效最差。
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Methods: Glipizide gliclazide glyburide glimepiride gliquidone repaglinide nateglinide pioglitazone rosiglitazone metformin phenformin and tolbutamide added in the blank ground samples were extracted with 80% methanol and were separated from an ACQUITY UPLC DBH C18 column with a gradient mobile phase of acetonitrile - 0.2 % formic acid water solution. A tandem quadrupole mass spectrometer equipped with electrospray ionization source was used in positive ion mode multiple reaction monitoring was performed to quantify above mentioned compounds.
被添加在中成药制剂及其包装物中的二甲双胍、苯乙双胍、罗格列酮、吡格列酮、格列吡嗫娶瑞格列奈、甲苯磺丁脲、格列齐特、格列苯脲、那格列奈、格列美脲、格列喹酮等西药成分用80%甲醇提取,以乙腈- 0.2%甲酸水溶液为流动相梯度洗脱,在ACQUITY UPLC DBH C18色谱柱上分离,串联四级杆质谱检测,MRM方式采集并定量。
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Box warning has been removed there is still some caution with heart failure but in reality all of the contraindications are based on a theoretical lactic acidemia which we have not really proven exists with metformin and so metformin remains the first line.
而实际上这些禁忌症都是基于理论上的乳酸性酸血症,而后者还没被证实确实是二甲双胍的不良反应。因此二甲双胍仍然是糖尿病治疗的一线药物。
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As soon as this research indicates metabolism syndrome patient to pass through the diagnosis namely to carry on pharmacological treatments and so on life style intervention and two armor biguanide, the life style intervention and adds the clothing two armor biguanides to have more explicit intervention effect.
研究表明代谢综合征病人应该一经诊断即进行生活方式干预和二甲双胍等药物治疗,生活方式干预并加服二甲双胍有更明确的干预效果。
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Results The highest drug use frequency was biguanide. There was 50.9% in the oral antidiabetic drug combination. Leading the first 3 places on the list of drug combination were sulfonylureas in combination with biguanide, sulfonylureas in combination with α-Glycosidace inhibitor, biguanide in combination with α-Glycosidace inhibitor, while there was 16.1% in 3 kinds combination. When oral antidiabetic drugs were combined with other drugs, combination with antihypertensives drugs led the fist, while with antihypertensives drugs led the second.
结果 二甲双胍使用频率最高,口服降糖药联合用药的比例高达50.9%,居前3位的依次是磺脲类+双胍类、磺脲类+α-葡萄糖苷酶抑制剂和双胍类+α-葡萄糖苷酶抑制剂,而3种以上口服降糖药联合用药的比例也达16.1%;口服降糖药与其他药物联合使用情况看,配合使用抗高血压药的频率最高,其次是降脂药。
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Results:Osteoblasts has the ability of transmembrane transport of metformin. The transport of metformin could be saturable with time and drug concentration adding;a certain range of temperature and pH can promote the transport of metformin;The transport of metformin was inhibited by cimetidine and phenformin,but promoted by verapamil;Oct1 but no Oct2 was expressed extensively in cell membrane and cytoplasm of osteoblasts;The protein level of Oct1 can be up-regulated by metformin with different drug concentrations and times,but no obvious differentces from each group.
结果:二甲双胍能够在成骨细胞上进行跨膜转运,且随着转运时间和药物浓度的增加而增加,并可达到饱和;一定范围内提高温度和pH值可以促进二甲双胍的转运;西米替丁和苯乙双胍对二甲双胍转运有明显抑制作用,而维拉帕米则对转运有明显的促进作用;Oct1广泛表达在成骨细胞的胞膜及胞浆中,而Oct2无表达;二甲双胍在不同浓度及不同给药时间均能够上调Oct1的表达,但各组间无明显差别。
- 更多网络解释与双胍相关的网络解释 [注:此内容来源于网络,仅供参考]
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biguanide:双胍
苯乙双胍(Biguanide)可引起母体酮血症或乳酸中毒,并使子代智商降低. 而胰鸟素不通过胎盘,对胎儿生长发育无影响,目前仍作为GDM首选药物. 长效及中效胰鸟素在GDM孕妇不宜采用,因其血糖变化难于调整剂量. 因此通常选用普通胰鸟素.
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biguanide:双胍 缩二胍(降血糖药)
bigtimer | 达到第一流水平的人 | biguanide | 双胍 缩二胍(降血糖药) | bigwig | 要人, 有重大影响的人
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Polyaminopropyl Biguanide:双胍,防腐剂
polyaminopropyl biguanide, 双胍,防腐剂 | panthenol, 维他命b5 | niacinamide, 维他命b3
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Polyaminopropyl Biguanide:聚氨丙基双胍
Acetyl Glucosamine 乙酰葡糖胺 | Polyaminopropyl Biguanide 聚氨丙基双胍 | Propylene Glycol Dicaprate 丙二醇二癸酸酯
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polyhexamethyl biguanide,PHMB:聚六甲基双胍
(1)阳离子防腐剂:体外试验表明阳离子防腐剂有很强的杀灭棘阿米巴滋养体及其包囊的作用,其作用机制是干扰了膜的功能. 临床上无论是作为首选用药,还是在其他药物治疗失败的情况下,都显示了良好的疗效. 目前常用的是0.02%的氯已定(chlorhexidine)和0.02%的聚六甲基双胍(polyhexamethyl biguanide PHMB),对角膜上皮没有明显的毒
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o-TOLYL BIGUANIDE o:甲苯基双胍
TOLUENE SULFONIC ACID 甲苯磺酸 | o-TOLYL BIGUANIDE o-甲苯基双胍 | TOPAZ 黄玉
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diformin:甘油二甲酸酯/二甲双胍
difmedol /地夫美多/ | diformin /甘油二甲酸酯/二甲双胍/ | difunctional /双作用/
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diformin:二甲双胍
difmedol 地夫美多 | diformin 二甲双胍 | diformin 甘油二甲酸酯
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diformin tablet:二甲双胍片
Difolotan 敌菌丹 | diformin tablet 二甲双胍片 | Diftoran 氟鼠烷
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Phenformin:苯乙双胍
[星岛网讯]加拿大卫生部警告消费者不要服用中成药 消糖宁 胶囊(Shortclean),因为该产品含有的处方药物成分"优降糖"(Glyburide)和"苯乙双胍"(Phenformin)可能对低血糖或糖尿病患者产生严重的健康危害.