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Methods The Streptococcus mitis isolated from patient's throat was shaking cultivated in Bact API 20 culture medium, the supernant fluid of which was precipitated with 20%、40%、60%、80%(NH4)2SO4, respectively. The fast protein liquid chromatography was used for final purification. The finally purified proteins were used to challenge rabbits suboutaneously and the responses of fever, diarrhea and reddening of the ears as well as mucous membranes were monitored.
将分离的缓症链球菌在Bact API 20培养基增菌培养后，所得上清液分别用20%、40%、60%、80%硫酸铵分段盐析，进一步快速蛋白液相色谱系统最终纯化，分别皮下注射新西兰兔观察有否体温升高、耳部及粘膜充血、腹泻等致热性表现。
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Results 20%(NH4)2SO4 precipitated protein of culture supernant fluid had a pyrogenic effect on rabbits.
结果 增菌培养上清液20%盐析段蛋白有致热性作用，可复制新西兰兔致热模型。
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Methods: The Yifuqing granula was given to rabbit with febrilis caused by the TAB vaccine. The effects of the Yifuqing granula on the ache threshold value of Jimpy mice caused by Hot plate, on auricle inflammatory swelling of Jimpy mice caused by dimethyl benzene, on the bacterium of Jimpy mice in vivo, and on CPE caused by virus were observed.
观察一服清颗粒对三联菌苗所致兔发热的影响；采用小鼠热板法观察一服清颗粒对小鼠痛阈的影响；观察一服清颗粒对二甲苯所致小鼠耳廓炎性肿胀的影响；采用小鼠体内抑菌实验观察一服清颗粒对金葡菌感染小鼠死亡率的影响；采用细胞病变法观察一服清颗粒对病毒致细胞病变作用的影响。
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tularemia：野兔热
并且长期在啮齿动物中流行.一旦当人或家栖鼠类进入疫源地,接触带菌动物或被疫蚤叮咬而发病,并通过鼠→蚤→鼠或鼠→蚤→人或人(菌血症时)→蚤→人的途径而传播,导致家栖鼠间和人间鼠疫的流行.野兔热(tularemia),兔粘液瘤(myxomatosis),
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tularaemia：土拉菌病 兔热病
tulaistle 图拉伊斯特尔纤维 | tularaemia 土拉菌病 兔热病 | tularemia 兔热病 野兔热