免疫发生

基本解释 (translations)

immunogenicity  ·  immunogenesis

与免疫发生相关的网络例句 [注：此内容来源于网络，仅供参考]

The immunoregulation activity of SPG-1 mainly existed in the part of sugar chain, but keeping its molecular structure intact had some effects on its immunoregulation activity; SPG sulphation had reducing effects on the immunoregulation of SPG-1, whereas, after medium and low acetification of SPG, the immunoregulation of SPG was enhanced. Conversely after high acetification, the immunoregulation of SPG-1 decreased, that is, after introducing sulfuric and acetic acid base in SPG-1, its immunoregulation changed. All of these indicated the structure of SPG-1 was closely connected with its immune activity.⑤.

甘薯糖蛋白SPG-1的免疫调节活性主要在其糖链部分，但保持分子结构的完整性对其免疫调节的活性有一定的作用；甘薯糖蛋白硫酸化对甘薯糖蛋白SPG-1的免疫调节有降低作用，而中、低度乙酰化后，可提高甘薯糖蛋白的免疫调节作用，高度乙酰化后则降低其免疫调节作用，即甘薯糖蛋白引入乙酰基和硫酸基团后，其免疫调节活性发生了改变，这些均表明了甘薯糖蛋白的结构与其免疫调节活性有密切的关系。

This study that observed the expression and distribution of 4 apoptotic factors, relation apoptotic factor with apoptosis, changes of T and B subgroup, and changes of molecular pathology in 14 cows suffering from enzootic bovine leucosis from several resides was detected by histochemistry, TUNEL technology, immune-fluorescent flow cytometry and so on. The aim of this experiment supplies theoretic basis for preventive and therapy of EBL, and consult dates for T lymphoid cell leucosis of human being .

本研究检查并剖检了14例临床与实验室诊断为EBL的病牛，观察分析了肿瘤发生的情况和特征，采用免疫组织化学ABC法、原位末端标记TUNEL技术和免疫荧光流式细胞检测法等技术，从EBL肿瘤细胞凋亡特性入手，围绕4种凋亡因子和几种免疫相关因子与EBL肿瘤发生的关系及其在诊治方面的应用进行了首次有价值的探索，其目的在于为防治EBL提供科学的理论依据，同时，也将为人类T细胞白血病Ⅰ。

It is characterized by malignant unusual hyperplasia and soading of cells in medulla ossium and other tissues, which can damage the normal hemopoiesis function and the mechanism of blood coagulation fibrinolysis and immunology.

机体的免疫功能与肿瘤的发生和发展有密切关系，当宿主免疫功能与肿瘤的发生和发展有密切关系，当宿主免疫功能低下或受抑制时，肿瘤发病率增高，而在肿瘤进行性生长时，患者的免疫功能进一步受到抑制。

RESULTS:After pinealectomized mice was irradiated WBI with 75 mGy X-rays,we found levels of plasma corticosterone increased obviously,and the effects of the proliferative reaction of splenocytes to ConA and spontaneous proliferation of thymocytes was found to be decrease. But injecting melatonin into pinealectomized mice or putting melatonin in the cultured cell,its immune functions might renew the enhancement.CONCLUSION:Melatonin of pineal gland might regulate the immunoenhancement induced by low dose radiation.MeSH Pineal body; Melatonin; Radiation; Corticosterone; Immunity,cellular

低剂量辐射(low dose radiation，LDR)全身照射(whole body irradiation，WBI)可引起免疫系统的兴奋效应，主要表现在以T淋巴细胞功能激活为主的细胞免疫和体液免疫功能的增强并可提高机体的抗瘤作用［4，5］，在LDR诱发免疫功能增强的同时伴有下丘脑-垂体-肾上腺皮质系统功能下调等神经内分泌功能的改变，神经内分泌对免疫系统的调节可能是LDR免疫兴奋效应发生的必要条件，松果腺MLT与辐射免疫兴奋效应的关系值得研究。

This subset is hyporesponsive and anergic to antigen stimulation. Recently, it has been demonstrated to participate in the immune deficiency in human immunodeficiency virus infection and has close relationship with the development of acquired immunodeficiency syndrome. Meanwhile, the CD4(superscript +)D25(superscript +)Treg is also infected when the human body is invaded by HIV. The CD4(superscript +)CD25(superscript +)Treg will finally be killed by the mechanism of antibody-dependent cell-mediated cytotoxicity. Because of the decrease of the CD4(superscript +)CD25(superscript +)Treg, it can't function as a immune suppressor as a result of the excess of activation of HIV and gradually exhausting of the T cell, which shows that the CD4(superscript +)CD25(superscript +)Treg plays a inhibitory role in the different stages of the development of the HIV as well as different effects in the pathogenesis of AIDS.

它能够抑制自身免疫病的发生和发展，参与肿瘤免疫的调节，同时在感染和移植免疫中也发挥着极其重要的作用。T细胞的这一亚群具有免疫调节和免疫抑制的特性，新近发现它亦与爱滋病的发生、发展关系密切HIV进入人体后，CD4D25调节性T细胞抑制了机体的免疫效应但它也同时被感染，最终由于细胞毒的作用而死亡由于调节性T细胞数量的减少不能有效的发挥其抑制作用，HIV持续的过度活化使得T细胞逐渐耗竭说明在HIV发生、发展的不同阶段Treg细胞可能都发挥了免疫抑制作用，但是却对HIV感染与爱滋病发病的进程产生了不同的效应。

As an immunomodulator NO may play a role like a double-edged sword since it expresses both in immuonchalleged and immunosspresed states. 2. After received external stimulus the morphology of ependyma of SFO could be changed and varied with time course, particularly its cellular apoptosis do occur and earlier than the ordinary areas of the brain. 3. Astrocytes in SFO could express cFos protein induced by LPS, suggesting the cells may maintain homeostasis in the brain in a longer period and modulate immune state of the brain. 4. As a CVO, SFO may sense changes of blood-bearing immunosignals earlier and instantly response to them, thus as one of windows of the brain SFO do take part in immunomodulation within the brain.

通过我们的实验结果我们可以得出这样一些初步的结论：1、一氧化氮作为免疫调质参与了机体免疫，它既能在免疫激发状态下又可在免疫抑制状态下进行表达提示，NO在脑内免疫调节中的作用可能是双向的。2、穹窿下器的室管膜形态在接受外界刺激后，随着时间的变化而不同，扫描电镜下的凋亡形态虽需进一步证实，但室管膜细胞确实发生了凋亡，并且穹窿下器发生的较早。3、穹窿下器内的星形胶质细胞在给予大肠杆菌后确实可以表达c-fos蛋白，并可能通过自身的激活来较长时间的维持体液的动态平衡，调节脑内免疫状态。4、穹窿下器作为感受性室周器官之一，能够较早的感受血携免疫信息的改变并及时作出反应，可能作为外周免疫信息进入脑内的窗口之一来参与脑的免疫调节。

Cellular immune response would occur later and would be weaker in xenogenic hepatocellular transplantation.

在异种肝细胞脾内移植中，细胞免疫发生的较迟和/或较弱。

PART Ⅱ IMMUNOPATHOLOGICAL EVIDANCE OF SIALIC ACID STRUCTURE IN CAMPYLOBACTER JEJUNI AS THE CRITICAL ANTIGEN TO INDUCE PERIPHERAL NEUROPATHY To demonstrate the critical role of NANA structure in the pathogenesis of allergic peripheral neuropathy induced by Campylobacter jejuni and provide immunopathological evidence to confirm the supposition of molecular mimicry and cross-immunity between CJ LPS and gangliosides in nerve.

LPS免疫后第2周实验豚鼠的免疫血清中，抗LPS IgG抗体滴度均明显增高，第3周达高峰，第5周仍维持在峰水平，野生株和突变株LPS免疫血清中的抗-野生株LPS IgG抗体滴度较各自免疫前分别增高8倍和4倍，抗-突变株LPS IgG抗体滴度则较各自免疫前分别增高6.5倍和15倍；(2)全身免疫后第3周和第5周，野生株LPS免疫血清中检测到较免疫前增高6倍的抗-GM1 IgG抗体，而NANA缺失的突变株LPS免疫血清中一直未检测到抗-GM1 IgG抗体；(3)野生株LPS免疫组中有17.3％的坐骨神经原纤维发生以轴索变性为主（占65％）的免疫性损伤，与突变株LPS免疫组和对照组比较均有显著性差异。

These data identify a complex role for MMPs and TIMPs in the immunopathogenesis of lung allograft rejection, and indicate their effects are not limited to matrix remodeling.

这些数据提示MMPs和TIMPs在肺移植排斥反应免疫发生机制中的复杂作用，提示其作用并不仅限于基质重塑。

According to correlative literatures, the diagnosis and treatment of bronchiolitis obliterans syndrome in three patients with hematological malignancies after allo-HSCT were analyzed. The function of haematopoiesis re-established successfully. The acute graft versus host disease did not occur in these patients except one patient occurred grade Ⅱ aGVHD, and the chronic graft versus host disease occurred in the 5th, 6th and 6th months after allo-HSCT respectively, but the cGVHD was recrudescent after treatment. The bronchiolitis obliterans syndrome occurred in the 9th, 7th and 11th months after allo-HSCT respectively, and they received the treatment of immunosuppressive, immune human serum globulin, azithromycin and to breathe in β2 receptor agonist and budesonide.

结合相关文献，对3例恶性血液病患者异基因造血干细胞移植后发生闭塞性细支气管炎综合征的临床特点和诊断治疗进行分析。3例患者移植后造血功能均顺利重建，2例未发生急性移植物抗宿主病，1例发生II度急性移植物抗宿主病；3例患者分别于移植后5，6，6个月发生广泛型慢性移植物抗宿主病，经治疗后病情仍有反复；3例患者分别于移植后9，7，11个月发生闭塞性细支气管炎综合征，给予免疫抑制剂、静脉免疫球蛋白、阿奇霉素及局部使用β2受体激动剂及布地奈德吸入治疗，2例在治疗4周后病情有所改善，另1例病情无改善。

与免疫发生相关的网络解释 [注：此内容来源于网络，仅供参考]

autoimmunity：自身免疫

自身免疫(autoimmunity)泛指机体免疫系统对自身抗原发生免疫应答,产生自身抗体和(或)自身致敏淋巴细胞的现象. 自身免疫反应并不一定导致自身免疫病,只有当自身免疫反应强度过高或持续较久,损伤了自身正常组织结构,并引起相应的临床症状时,

immunization：使免疫

蛋白质缺乏,会使犬体内蛋白质代谢失去平衡,引起食欲下降、体重减轻、生长缓慢、血液内蛋白质含量降低,使免疫(immunization)力降低. 公犬精液品质下降、精子数量减少. 母犬发情异常、不受孕,即使受孕,胎儿也常因发育不良而发生死胎或畸胎.

immunodeficiency diseases：免疫缺陷病

免疫缺陷病(immunodeficiency diseases)是一组由于免疫系统发育不全或遭受损害所致的免疫功能缺陷引起的疾病. 有二种类型:①原发性免疫缺陷病,又称先天性免疫缺陷病,与遗传有关,多发生在婴幼儿. ②继发性免疫缺陷病,又称获得性免疫缺陷病,可发生在任何年龄,

immunogen：免疫原

抗原( antigen, Ag ); 免疫原(immunogen):能刺激诱导机体发生免疫应答并能与相应抗体或T 淋巴细胞受体发生特异性免疫反应的大分子物质. 免疫原性(immunogenicity); 抗原性(antigenicity). 免疫反应性(immunoreactivity);

immunogenicity：免疫原性

抗原通常具有两种性能:①免疫原性 免疫原性(immunogenicity):系指抗原能够刺激 免疫原性 机体免疫系统发生免疫应答,产生抗体和/或致敏淋巴细胞的性能;②免疫反应 免疫反应 指抗原能与相应抗体和/或致性(immunoreactivity)或反应原性(reactivity): 敏淋巴细胞特异性结合,

immunogenicity：致免疫力 免疫发生 免疫原性

immunogenic 致免疫的 | immunogenicity 致免疫力 免疫发生 免疫原性 | immunoglobulin 免疫球蛋白 丙种球蛋白

premunition：带虫免疫

如疟疾的"带虫免疫"(premunition)和血吸虫诱导的"伴随免疫"(concomitant免疫应答(immune response)是指宿主对特异的寄生虫抗原产生的免疫反应过程,包括抗原的处理与呈递,T细胞的激活和淋巴因子的产生,以及发生体液免疫和细胞免疫效应.

Sneaking through：免疫逃逸

[摘要]免疫逃逸(sneaking through)是指躲避机体免疫监视作用的现象. HLA分子表型的下调、缺失或异常表达,目前被认为是肿瘤、母胎等发生免疫逃逸的主要原因. 其机制除由HLA-I、Ⅱ类分子表型下调和(或)缺失,而导致的对肿瘤的免疫监视作用下降是一方面外,

immunogenetic：免疫遗传的

immunogenesis 免疫发生 | immunogenetic 免疫遗传的 | immunogenetics 免疫遗传的

immunologically privileged site：免疫赦免区

免疫赦免区(immunologically privileged site )是 机体接受同种或异种移植后不发生或仅发生轻微排斥反应的部位. 这些特殊的解剖部位包括胸腺、...1. 免疫隔离部位抗原的释放:免疫隔离部位(immunologically privileged site)是指脑、睾丸、...