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When the Mosquito bites, it releases the sporozoites, which enter human liver cells through the bloodstream and reproduce asexually
蚊虫叮咬人的时候就释放出子孢子,它通过血流进入肝细胞,并且进行无性生殖。
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Following 72 h co-culture, desquamate, sporozoites, trophozoites, meronts, microgametocytes, macrogametocytes, zygote, thin-wall oocyst, and thick-wall oocyst appeared orderly. Between the 60th and 72th hour, many oocysts emerged. Inoculated by the C. parvum -infected cell culture supernatant at the 48th hour, the immunosuppressed mice became infected.
在感染后72 h内,隐孢子虫出现连续发育阶段,包括脱囊、子孢子、裂殖子、裂殖体、滋养体、配子体、合子、薄壁卵囊和厚壁卵囊,在60~72 h内形成卵囊;用感染48 h的细胞培养上清接种于免疫抑制小鼠, 10 d后有隐孢子虫卵囊排出。
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The author first reported the social phenomenon and synchronizing development incryptosporidia,the dynamic process of the sporozoites or merozoites aparted from theirparent substances and developed into trophozoites,the culture of C.baileyi in chickenembryo,and the excysting process without both the trypsin and the sodium taurocholatein 37℃ water.The high levels of excystation(60%)oceured at 37℃ water showedthat temprature was very important in cryptosporidia excysting process.
在国内首次观察和描述了薄壁型隐孢子虫卵囊;首次报道隐孢子虫具有群体寄生现象和同步发育特征;首次描述了隐孢子虫的裂殖子或子孢子离开母体和发育为滋养体的动态变化过程;首次应用粪便中纯化的C.baileyi卵囊感染鸡胚成功,并用37℃水脱囊,其脱囊率高达60%,表明温度对隐孢子虫的脱囊具有重要作用,无需胰酶和牛胆酸钠的参与。
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After a meiotic reduction in chromosome number sporozoites are formed within the oocyst.
在对染色体数目的减数分裂的减少以後子孢子在oocyst之内被形成。
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Eventually the oocyst ruptures and the sporozoites migrate to the salivary gland where they await transfer to the vertebrate host.
最终oocyst破裂和子孢子移居到他们等候调动到脊椎动物的主人的唾腺。
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