sparteine ['spɑ:tii:n; -ti:in]
- sparteine的基本解释
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n.
[化]鹰爪豆碱, 金雀花碱
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A similar initiator, Et_2Zn/-Sparteine, yielded polys with threo-diisotactic -rich structure in the main chain, indicative of strongly asymmetric inducation in this system. In this case, no polymeric complexes in-site formed because of the intensive coordination between sparteine and Zn ions.The binary initiating system composed of Et_2Zn and n-BuLi combined the advantages of both metal alkyls, which gave the polymers with higher molecular weights and moderate optical activity ~(25_D =-97.1°~+24.3°.
Et_2Zn/n-BuLi二元引发体系综合了两种金属烷基化物的优点,得到了分子量相对较高(M_n=1.4x10~3~4.9×10~3)且含有手性超分子结构的光学活性聚合物;聚合物中锌含量的微小变化可引起聚合物光学活性明显改变,超分子手性与聚合物侧基的绝对构型存在关联。
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The polymerization characteristics have been examined in detail for the oxazoline-substituted N-phenylmaleimides with initiators including n-BuLi, Et_2Zn, Et_2Zn/-Sparteine, and Et_2Zn/n-BuLi.
发现:在n-BuLi引发下获得的光学活性聚合物最高比旋光度达到-60.0°~(25D,数均分子量为2×10~3~6×10~3;聚合物的比旋光度随着分子量的增大而线性增加,poly出现了旋光方向翻转现象,临界分子量为M_n=2700。
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Result: Eight compounds were isolated and identified as matrine,sophoridine,sophocarpine,sophoramine,oxymatrine,oxysophocarpine,aloperine and sparteine.
结果:分离鉴定出8个化合物:苦参碱、槐定碱(sophoridine,Ⅱ)、槐果碱(sophocarpine,Ⅲ)、槐胺碱(sophoramine,Ⅳ)、氧化苦参碱(oxymatrine,Ⅴ)、氧化槐果碱(oxysophocarpine,Ⅵ)、苦豆碱(aloperine,Ⅶ)和鹰爪豆碱(sparteine,Ⅷ)。
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sparteine:司巴丁
Evans 等报道:对降压药胍喹定(debrisoquine),抗心律失常药司巴丁(sparteine)氧化能力弱的个体是由于P450 基因多态性所致. 之后,Dayer 等进一步证实了各种各样药物的血中浓度与P450基因的多态性有关. 至此,遗传药理学完善了其理论基础,
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sparteine:鹰爪豆碱
分布较广的有苦参碱(matrine)(48-72)、野决明碱(thermopsine)(48-78)、金雀花碱(cytisine)(48-57)、鹰爪豆碱(sparteine)(48-79)等. 苦参碱及槐属的类似生物碱主要作用于中枢神经系统,产生呼吸抑制、运动失调和惊厥.
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sparteine:金雀花碱
对2D6酶(异喹胍(debrisoquine)羟化酶)的研究很多,它参与大量药物的代谢,如异喹胍、三环类抗抑郁药、选择性5-羟色胺再摄取抑制剂(除外fluvoxamine)、镇痛药(可待因、右美沙芬(dextromethorphan))、抗心律失常药(金雀花碱(sparteine)、恩卡尼encai
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sparteine:鹰爪豆碱/金雀花碱
Sorbitol 山梨醇 | Sparteine 鹰爪豆碱/金雀花碱 | Sparteine sulfate 硫酸金雀花碱
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Sparteine sulfate:硫酸金雀花碱
Sparteine 鹰爪豆碱/金雀花碱 | Sparteine sulfate 硫酸金雀花碱 | Spiraeoside 绣线菊甙
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