polysomy
- polysomy的基本解释
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多体性, 多染色体
- 更多网络例句与polysomy相关的网络例句 [注:此内容来源于网络,仅供参考]
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Polysomy, which includes trisomy, is the condition in which one or more chromosomes are represented more than twice in the cell.
多染色体包括三染色体都是一条或多条染色体代替了正常细胞中的两条染色体形成的。
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Purpose: Polysomy 17 is frequently found in breast cancer and may complicate the interpretation of HER-2 testing results.
但是,17号染色体多体会对HER2状态检测结果解读造成很大的影响。
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And the one with both amplification of HER2 gene and polysomy of chromosome 17 was also moderately positive expression for the protein.
FISH技术可稳定地检测用IHC确定的HER2蛋白阳性乳腺癌中HER2基因的扩增状况,并用于临床赫赛汀分子靶向治疗病例的筛选。
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We investigated the impact of polysomy 17 on HER-2 testing and studied its clinicopathologic significance in relation to HER2 gene amplification.
该研究的FISH结果显示,44例患者的HER2绝对拷贝数达可疑阳性,但如果结合17号染色体多体因素(HER2/Chr17),这些患者均为HER2阴性。
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On its own, polysomy 17 was not associated with HER-2 overexpression on IHC or increased HER2 mRNA levels by RT-PCR. Moreover, and in contrast with HER2 gene amplification, polysomy 17 was not associated with high tumor grade, hormone receptor negativity, or reduced disease-free survival.Conclusion: Polysomy 17 affects HER-2 testing in breast cancer and is a major cause of equivocal results by FISH.
不过,在J Clin Oncol同期配发的一篇述评中,美国波士顿大学医学中心的罗森伯格指出,当务之急不是直接进行这样的研究,而是应该对已有研究的IHC、FISH和有效率数据进行回顾或再分析,以明确是否无HER2扩增的17号染色体多体肿瘤被归入不同类别(HER2阴性、阳性),并由此导致关于HER2靶向治疗疗效的结果不一致。
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- 更多网络解释与polysomy相关的网络解释 [注:此内容来源于网络,仅供参考]
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Polysomatic monstrosity; Polysomy:多体畸形
Polyscelous monster 多足畸胎; 多腿畸胎 | Polysomatic monstrosity; Polysomy 多体畸形 | Polystichy 多眉(畸形)
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polysomy:多体型
3、多体型(polysomy) 某号染色体增加了两条或两条以上. 主要见于性染色体异常,...
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polysomy:多体性
polysoap 聚皂 | polysomy 多体性 | polyspast 滑车组
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polysomy:多染色体
polysomia 多体 | polysomy 多染色体 | polyspermia 精液过多